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- Wu, Yunzhou; He, Jinjiao; An, Ying; Wang, Xi; Liu, Yunye; Yan, Shijun; Ye, Xianlong; Qi, Jianying; Zhu, Shenglong; Yu, Qingzhong; Yin, Jiechao; Li, Deshan; Wang, Wenfei
- Journal of Pharmacological Sciences 2016 v.132 no.1 pp. 24-30
- Newcastle disease virus; antineoplastic activity; clinical trials; hepatoma; humans; immune response; immunologic memory; immunostimulants; immunostimulation (physiological); in vivo studies; interleukin-2; laboratory animals; lymphocytes; mice; microbial growth; neoplasm cells; therapeutics; vaccines; viruses
- ... Newcastle disease virus (NDV) have shown oncolytic therapeutic efficacy in preclinical study and are currently approved for clinical trials. NDV Anhinga strain which is a mesogenic strain should be classified as lytic strain and has a therapeutic efficacy in hepatocellular cancer. In this study, we evaluated the capacity of NDV Anhinga strain to elicit immune reaction in vivo and the possibility f ...