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- Le Roch, Karine G., et al. Show all 12 Authors
- Journal of Proteome Research 2016 v.15 no.8 pp. 2787-2801
- DNA replication; Plasmodium falciparum; cell cycle; chromatin; epigenetics; gene expression; histones; malaria; mass spectrometry; monitoring; parasites; proteome; transcription (genetics); virulence
- ... A major obstacle in understanding the complex biology of the malaria parasite remains to discover how gene transcription is controlled during its life cycle. Accumulating evidence indicates that the parasite’s epigenetic state plays a fundamental role in gene expression and virulence. Using a comprehensive and quantitative mass spectrometry approach, we determined the global and dynamic abundance ...
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