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- Lagemann, Annika; Dunkel, Andreas; Hofmann, Thomas
- Journal of agricultural and food chemistry 2012 v.60 no.29 pp. 7211-7217
- Lactuca sativa; aldosterone; angiotensin I; angiotensin II; antihypertensive agents; blood pressure; fractionation; functional foods; glycosidases; glycosides; hydrochloric acid; hydrolysis; inhibitory concentration 50; ion exchange chromatography; lettuce; nuclear magnetic resonance spectroscopy; peptidyl-dipeptidase A; phytochemicals; renin; saliva; stomach
- ... Angiotensin-converting enzyme (ACE), playing a crucial role in the renin angiotensin aldosterone system, is well-known to catalyze the conversion of the decapeptide angiotensin I into the physiologically active octapeptide angiotensin II, triggering blood pressure increasing mechanisms. To meet the demand for natural phytochemicals as antihypertensive agents in functional food development, extract ...