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- Yen, G.C.; Yeh, C.T.; Chen, Y.J.
- Journal of agricultural and food chemistry 2004 v.52 no.13 pp. 4121-4127
- hepatotoxicity; caffeic acid; oxidative stress; glutathione-disulfide reductase; hepatotoxins; Lamiaceae; lipid peroxidation; medicinal plants; plant extracts; enzyme activity; glutathione peroxidase; rats; antioxidant activity; oral administration; antioxidants; herbal medicines; hepatoprotective effect
- ... The protective effect of Hsian-tsao (Mesona procumbens Hemsl.) and its active compounds on liver damage was evaluated using the model of tert-butyl hydroperoxide (t-BHP)-induced acute hepatic damage in rats. Male Sprague-Dawley rats (200 ± 10 g) were orally pretreated with a water extract of Hsian-tsao (WEHT) (0.1, 0.5, and 1.0 g/kg) or caffeic acid (0.1 g/kg of body weight) for 13 days before a s ...