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You searched for: Journal Journal of agricultural and food chemistry Remove constraint Journal: Journal of agricultural and food chemistry Source 2017 v.65 no.1 Remove constraint Source: 2017 v.65 no.1 Subject rats Remove constraint Subject: rats
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1. Blueberry Anthocyanin-Enriched Extracts Attenuate Fine Particulate Matter (PM2.5)-Induced Cardiovascular Dysfunction

Author:
Wang, Ziyu; Pang, Wei; He, Congcong; Li, Yibo; Jiang, Yugang; Guo, Changjiang
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 87-94
ISSN:
1520-5118
Subject:
angiotensin II; apoptosis; biomarkers; blueberries; electrocardiography; endothelins; heart; heart rate; histopathology; inflammation; interleukin-10; interleukin-6; malondialdehyde; oxidative stress; particulates; protein synthesis; rats; superoxide dismutase
Abstract:
... Blueberry anthocyanin-enriched extracts (BAE) at three doses (0.5, 1.0, and 2.0 g/kg) were administered by oral gavage to rats exposed to 10 mg/kg fine particulate matter (PM₂.₅) three times a week. A positive control group was exposed to PM₂.₅ without BAE treatment. We analyzed heart rate (HR), electrocardiogram (ECG), and histopathology, and biomarkers of cardiovascular system injuries, systemic ...
DOI:
10.1021/acs.jafc.6b04603

2. Comprehensive Analysis of Tiamulin Metabolites in Various Species of Farm Animals Using Ultra-High-Performance Liquid Chromatography Coupled to Quadrupole/Time-of-Flight

Author:
Sun, Feifei; Yang, Shupeng; Zhang, Huiyan; Zhou, Jinhui; Li, Yi; Zhang, Jinzhen; Jin, Yue; Wang, Zhanhui; Li, Yanshen; Shen, Jianzhong; Zhang, Suxia; Cao, Xingyuan
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 199-207
ISSN:
1520-5118
Subject:
biochemical pathways; biotransformation; chickens; cows; dysentery; goats; hydroxylation; metabolism; metabolites; pneumonia; rats; swine; tiamulin; ultra-performance liquid chromatography; veterinary clinics
Abstract:
... Tiamulin is an antimicrobial widely used in veterinary practice to treat dysentery and pneumonia in pigs and poultry. However, knowledge about the metabolism of tiamulin is very limited in farm animals. To better understand the biotransformation of tiamulin, in the present study, in vitro and in vivo metabolites of tiamulin in rats, chickens, swine, goats, and cows were identified and elucidated u ...
DOI:
10.1021/acs.jafc.6b04377