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- Choi, Jung-Hye, et al. Show all 5 Authors
- Journal of agricultural and food chemistry 2017 v.65 no.36 pp. 7893-7899
- Syzygium aromaticum; antineoplastic activity; apoptosis; buds; caspase-3; chemokine CCL5; cloves; cytotoxicity; flavonoids; herbal medicines; humans; interleukin-10; macrophages; neoplasm cells; ovarian neoplasms; propidium; staining; vascular endothelial growth factors
- ... The flower bud of Syzygium aromaticum (clove) has been used for centuries as a spice and herbal medicine. The biological activities of kumatakenin, a flavonoid that has recently been isolated from cloves, are poorly characterized. In the present study, the anticancer effects of kumatakenin in human ovarian cancer cells and tumor-associated macrophages (TAMs) were investigated. We found that kumata ...
- Choi, Jung-Hye, et al. Show all 8 Authors
- Journal of agricultural and food chemistry 2016 v.64 no.15 pp. 3048-3053
- Syzygium aromaticum; animal ovaries; buds; chemical structure; chromatography; cytotoxicity; ethanol; flavonols; humans; inhibitory concentration 50; neoplasm cells; nuclear magnetic resonance spectroscopy; ovarian neoplasms; spectral analysis
- ... Repeated chromatography of the EtOAc-soluble fraction from the 70% EtOH extract of the flower buds of Syzygium aromaticum (clove) led to the isolation and characterization of four new flavonol glucuronides, rhamnetin-3-O-β-d-glucuronide (1), rhamnazin-3-O-β-d-glucuronide (2), rhamnazin-3-O-β-d-glucuronide-6″-methyl ester (3), and rhamnocitrin-3-O-β-d-glucuronide-6″-methyl ester (4), together with ...