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- Choi, Jung-Hye, et al. Show all 5 Authors
- Journal of agricultural and food chemistry 2017 v.65 no.36 pp. 7893-7899
- Syzygium aromaticum; antineoplastic activity; apoptosis; buds; caspase-3; chemokine CCL5; cloves; cytotoxicity; flavonoids; herbal medicines; humans; interleukin-10; macrophages; neoplasm cells; ovarian neoplasms; propidium; staining; vascular endothelial growth factors
- ... The flower bud of Syzygium aromaticum (clove) has been used for centuries as a spice and herbal medicine. The biological activities of kumatakenin, a flavonoid that has recently been isolated from cloves, are poorly characterized. In the present study, the anticancer effects of kumatakenin in human ovarian cancer cells and tumor-associated macrophages (TAMs) were investigated. We found that kumata ...
- Choi, Jung-Hye, et al. Show all 6 Authors
- Journal of agricultural and food chemistry 2016 v.64 no.3 pp. 570-578
- Ecklonia; animal models; blood serum; dietary supplements; health foods; inducible nitric oxide synthase; ingredients; interleukin-6; kidneys; liver; macrophages; mice; nitric oxide; phenol; protective effect; septic shock; small interfering RNA; survival rate; toxicity; transcription factor NF-kappa B; tumor necrosis factor-alpha; Japan; Korean Peninsula
- ... Brown algae have been recognized as a food ingredient and health food supplement in Japan and Korea, and phlorotannins are unique marine phenol compounds produced exclusively by brown algae. Sepsis is a whole-body inflammatory condition with a mortality rate of 30–40%. Here, we investigated the effects of a phlorotannin-rich extract of the edible brown alga Ecklonia cava against hyper-inflammatory ...