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- Li, Shuyi, et al. Show all 8 Authors
- Journal of agricultural and food chemistry 2017 v.65 no.9 pp. 1893-1899
- Litchi; absorption; bioavailability; biochemical pathways; gastrointestinal system; ingestion; metabolites; pericarp; pharmacokinetics; polymerization; procyanidins; quantitative structure-activity relationships; rats; shikimic acid
- ... The bioavailability of A-type procyanidins in vivo has been rarely investigated; as such, this study discusses the effect of A-type linkage and degree of polymerization on the metabolism of procyanidins extracted from litchi pericarp (LPOPC). Sprague–Dawley rats were gavaged with (−)-epicatechin (EC) and LPOPC and sacrificed at different time points after ingestion. A-type linkage procyanidin olig ...
- Li, Shuyi, et al. Show all 6 Authors
- Journal of agricultural and food chemistry 2019 v.67 no.12 pp. 3354-3362
- Litchi; adenocarcinoma; bioavailability; confocal laser scanning microscopy; electrical resistance; high performance liquid chromatography; human cell lines; humans; mass spectrometry; models; pH; pericarp; permeability; procyanidins; stomach; toxicity testing
- ... It has been proven that A-type procyanidins, containing an additional ether bond, compared to B-type procyanidins are also bioavailable in vitro and in vivo. However, their bioavailability and absorption in the gastrointestinal tract remain uncertain. In this study, a model of the human adenocarcinoma stomach cell line (MKN-28) was established to explore the cellular transport of flavanolic monome ...