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You searched for: Journal Journal of applied microbiology Remove constraint Journal: Journal of applied microbiology Publication Year 2019 Remove constraint Publication Year: 2019 Source 2019 v.126 no.2 Remove constraint Source: 2019 v.126 no.2 Subject minimum inhibitory concentration Remove constraint Subject: minimum inhibitory concentration Subject adenosine triphosphate Remove constraint Subject: adenosine triphosphate Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Natural products show diverse mechanisms of action against Clostridium difficile

Author:
Roshan, N.; Riley, T.V.; Knight, D.R.; Steer, J.H.; Hammer, K.A.
Source:
Journal of applied microbiology 2019 v.126 no.2 pp. 468-479
ISSN:
1364-5072
Subject:
Clostridium difficile; Escherichia coli; Leptospermum scoparium; absorbance; adenosine triphosphate; allicin; antibacterial properties; antibiotic resistance; bulbs; cell membranes; cell suspension culture; cinnamon; garlic; mechanism of action; menthol; minimum inhibitory concentration; peppermint oil; propidium; protein synthesis
Abstract:
... AIMS: To investigate the mechanisms of action of natural products with bactericidal (cinnamon root powder, peppermint oil, trans‐cinnamaldehyde, menthol and zingerone) or bacteriostatic (fresh garlic bulb extract, garlic clove powder, Leptospermum honey and allicin) activity against two Clostridium difficile strains. METHODS AND RESULTS: Bactericidal products significantly reduced intracellular AT ...
DOI:
10.1111/jam.14152