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- Durack, Juliana; Burke, Thomas P.; Portnoy, Daniel A.
- Journal of bacteriology 2015 v.197 no.5 pp. 932-942
- Listeria monocytogenes, etc ; Gram-positive bacteria; adenosine triphosphate; adenosinetriphosphatase; bacterial motility; bacterial proteins; gametolysin; humans; hydrolysis; lysozyme; mice; mutants; operon; pathogenesis; pathogens; point mutation; protein secretion; sequence analysis; tissue culture; virulence; Show all 20 Subjects
- ... The bulk of bacterial protein secretion occurs through the conserved SecY translocation channel that is powered by SecA-dependent ATP hydrolysis. Many Gram-positive bacteria, including the human pathogen Listeria monocytogenes , possess an additional nonessential specialized ATPase, SecA2. SecA2-dependent secretion is required for normal cell morphology and virulence in L. monocytogenes ; however, ...
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- Zébréé, Arthur Constant; Akééé, Francine Moussan; Ventroux, Magali; Koffi-Nevry, Rose; Noirot-Gros, Marie-Francoise; Deutscher, Josef; Milohanic, Eliane
- Journal of bacteriology 2015 v.197 no.9 pp. 1559-1572
- Listeria monocytogenes, etc ; Listeria innocua; alleles; dephosphorylation; foodborne illness; gene expression; glucose; histidine; humans; listeriosis; mannose; mutants; operon; pathogens; phosphorylation; transcription (genetics); transcription factors; two hybrid system techniques; virulence; Show all 19 Subjects
- ... Listeriae take up glucose and mannose predominantly through a mannose class phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS ᴹᵃⁿ), whose three components are encoded by the manLMN genes. The expression of these genes is controlled by ManR, a LevR-type transcription activator containing two PTS regulation domains (PRDs) and two PTS-like domains (enzyme IIA ᴹᵃⁿ [EIIA ᴹᵃⁿ]- and EIIB ᴳᵃ ...
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