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- Ganguli, Nirmalya, et al. Show all 4 Authors
- Journal of biotechnology 2015 v.198 pp. 53-59
- buffaloes; recombinant DNA; epithelial cells; biopharmaceuticals; milk; epithelium; promoter regions; genetically modified organisms; bioreactors; gene expression; remediation; buffalo milk; mammary glands; patients; introns; females; humans; transcription (genetics); mice; transfection; exons; green fluorescent protein; beta-casein; lactation; microorganisms; body fluids; milk production; cost effectiveness
- ... Therapeutic proteins are produced in microbes, mammalian cell lines, and body fluids by applying recombinant DNA technology. They are required for compensating the deficiency of essential proteins in patients. Animal bioreactors producing such valuable bio-pharmaceuticals in body fluids have lately emerged as efficient and cost-effective expression systems. Promoters, along with other regulatory e ...