Journal name: Journal of chromatography / Subject term: derivatization / Text availability: Citation in PubAg

1. Simplified method for determination of polycarbamate fungicide in water samples by liquid chromatography with tandem mass spectrometry following derivatization with dimethyl sulfate

Author:: Hayama, T.; Yada, K.; Onimaru, S.; Yoshida, H.; Todoroki, K.; Nohta, H.; Yamaguchi, M.
Source:: Journal of chromatography 2007 v.1141 no.2 pp. 251-258
ISSN:: 0021-9673
Subject:: carbamate pesticides; pesticide residues; water pollution; solid phase extraction; chemical reactions; dimethyl sulfate; mass spectrometry; liquid chromatography; water analysis
DOI:: 10.1016/j.chroma.2006.12.038
: https://doi.org/10.1016/j.chroma.2006.12.038

2. A denuder-impinger system with in situ derivatization followed by gas chromatography-mass spectrometry for the determination of gaseous iodine-containing halogen species

Author:: Huang, Ru-Jin; Hoffmann, Thorsten
Source:: Journal of chromatography 2008 v.1210 no.2 pp. 135-141
ISSN:: 0021-9673
Subject:: derivatization; methanol; relative humidity; atmospheric chemistry; ozone depletion; troposphere; carbon tetrachloride; iodine; gas chromatography-mass spectrometry
Abstract:: ... Reactive iodine species have been suggested to play an important role in the atmosphere (e.g. tropospheric ozone depletion, coastal new particle formation). However, there still exist major uncertainties about their atmospheric chemistry, mostly due to the lack of analytical approaches for the accurate speciation of certain key compounds. In this study, 1,3,5-trimethoxybenzene (1,3,5-TMB)-coated d ...
DOI:: 10.1016/j.chroma.2008.08.003
: https://doi.org/10.1016/j.chroma.2008.08.003

3. A novel derivatization approach for simultaneous determination of glyoxal, methylglyoxal, and 3-deoxyglucosone in plasma by gas chromatography-mass spectrometry

Author:: Wu, Meng-Yan; Chen, Bud-Gen; Chang, Chiung Dan; Huang, Mei-Han; Wu, Tai-Guang; Chang, Daw-Ming; Lee, Yau-Jiunn; Wang, Hsiang Ching; Lee, Chu-I; Chern, Chi-Liang; Liu, Ray H.
Source:: Journal of chromatography 2008 v.1204 no.1 pp. 81-86
ISSN:: 0021-9673
Subject:: glycation; carbonyl compounds; derivatization; acetonitrile; patients; toxicity; gas chromatography-mass spectrometry
Abstract:: ... A two-step derivatization approach has been developed to enable the simultaneous analysis of glyoxal, methylglyoxal, and 3-deoxyglucosone by the most efficient and widely applied GC-MS methodology. These three analytes are reactive carbonyl compounds associated with the formation of advanced glycation and lipoxidation end products, a process thought to contribute to uremic toxicity and referred to ...
DOI:: 10.1016/j.chroma.2008.07.040
: https://doi.org/10.1016/j.chroma.2008.07.040

4. Active single-drop microextraction for the determination of gaseous diisocyanates

Author:: Batlle, Ramón; López, Patricia; Nerín, Cristina; Crescenzi, Carlo
Source:: Journal of chromatography 2008 v.1185 no.2 pp. 155-160
ISSN:: 0021-9673
Subject:: biphenyl; chromatography; derivatization; detection limit; models; screening; solid phase microextraction; solvents
Abstract:: ... This paper presents a novel application of active single-drop microextraction (SDME) for the determination of mixtures of four gaseous diisocyanates: 2,4- and 2,6-toluene diisocyanate (TDI), hexamethylene diisocyanate (HDI) and methylene diphenyl diisocyanate (MDI). The optimised simultaneous extraction, preconcentration and derivatization method utilizes a 2.3-μL Milli-Q water drop containing dib ...
DOI:: 10.1016/j.chroma.2008.01.053
: https://doi.org/10.1016/j.chroma.2008.01.053

5. Analysis of formaldehyde formation in wastewater using on-fiber derivatization-solid-phase microextraction-gas chromatography-mass spectrometry

Author:: Trenholm, Rebecca A.; Rosario-Ortiz, Fernando L.; Snyder, Shane A.
Source:: Journal of chromatography 2008 v.1210 no.1 pp. 25-29
ISSN:: 0021-9673
Subject:: derivatization; detection limit; organic matter; hydrogen peroxide; solid phase microextraction; oxidation; wastewater; formaldehyde; gas chromatography-mass spectrometry
Abstract:: ... A method has been developed for the quantification of the formation of formaldehyde during the advanced oxidation treatment (AOT) of wastewater destined for reuse. This method uses solid-phase microextraction (SPME) with on-fiber derivatization followed by gas chromatography-mass spectrometry (GC-MS) analysis. Based on calculated method detection limits (MDL) and ambient background levels, the met ...
DOI:: 10.1016/j.chroma.2008.09.044
: https://doi.org/10.1016/j.chroma.2008.09.044

6. Application of acetate derivatives for gas chromatography-mass spectrometry: Novel approaches on carbohydrates, lipids and amino acids analysis

Author:: Sassaki, Guilherme L.; Souza, Lauro M.; Serrato, Rodrigo V.; Cipriani, Thales R.; Gorin, Philip A.J.; Iacomini, Marcello
Source:: Journal of chromatography 2008 v.1208 no.1-2 pp. 215-222
ISSN:: 0021-9673
Subject:: derivatization; acetates; ions; glycoconjugates; lipids; amino acids; acetylation; uronic acids; gas chromatography-mass spectrometry
Abstract:: ... The structure of glycoconjugates has been determined by several chromatographic methods, however gas chromatography-mass spectrometry (GC-MS) has been widely used to identify and quantify the volatile trimethylsilyl and fluoroacyl derivatives. Adapting the reduction/acetylation strategies, we had performed the derivatization of all monosaccharide class, as well as amino acids and OH-fatty acids as ...
DOI:: 10.1016/j.chroma.2008.08.083
: https://doi.org/10.1016/j.chroma.2008.08.083

7. Automated on-line in-tube solid-phase microextraction-assisted derivatization coupled to liquid chromatography for quantifying residual dimethylamine in cationic polymers

Author:: Prieto-Blanco, M.C.; Cháfer-Pericás, C.; López-Mahía, P.; Campíns-Falcó, P.
Source:: Journal of chromatography 2008 v.1188 no.2 pp. 118-123
ISSN:: 0021-9673
Subject:: cationic surfactants; cost effectiveness; derivatization; desorption; detection limit; dimethylamine; flocculants; high performance liquid chromatography; polymers; solid phase microextraction; water treatment
Abstract:: ... A method for the analysis of dimethylamine (DMA) by automated in-tube solid-phase microextraction (IT-SPME)-supported chemical derivatization coupled with high-performance liquid chromatography was developed. Extraction, derivatization and desorption were studied by using a capillary coated with 95% polydimethylsiloxane and 5% polydiphenylsiloxane. Solution derivatization and automated IT-SPME der ...
DOI:: 10.1016/j.chroma.2008.02.056
: https://doi.org/10.1016/j.chroma.2008.02.056

8. Capillary electrochromatographic separation of racemates on a norvancomycin-bonded monolithic column under reversed-phase conditions

Author:: Ding, Guo-Sheng; Tang, An-Na
Source:: Journal of chromatography 2008 v.1208 no.1-2 pp. 232-238
ISSN:: 0021-9673
Subject:: antibiotics; chromatography; derivatization; enantiomers; glycopeptides; pH; silica; sol-gel processing; warfarin
Abstract:: ... Following a modified sol-gel process, a silica backbone was prepared in a fused-silica capillary, and it was then chemically modified with a glycopeptide antibiotic, norvancomycin (NVC), by a one-step in situ derivatization process. Several selected neutral and basic racemates were assessed on this column under reversed-phase conditions. The influences of pH and composition of mobile phase on enan ...
DOI:: 10.1016/j.chroma.2008.08.075
: https://doi.org/10.1016/j.chroma.2008.08.075

9. Capillary electrophoresis of aminoglycosides with argon-ion laser-induced fluorescence detection

Author:: Lin, Yi-Fang; Wang, Yung-Chi; Chang, Sarah Y.
Source:: Journal of chromatography 2008 v.1188 no.2 pp. 331-333
ISSN:: 0021-9673
Subject:: aqueous solutions; capillary electrophoresis; chromatography; derivatization; detection limit; fluorescence; humans; pH; sodium borate; tobramycin
Abstract:: ... A new analytical method for aminoglycosides (kanamycin, bekanamycin, paromomycin and tobramycin) based on capillary electrophoretic separation and argon-ion laser-induced fluorescence detection has been developed. 6-Carboxyfluorescein succinimidyl ester (CFSE) was used for precolumn derivatization of the non-fluorescent aminoglycosides. Optimal separation and detection were obtained with an electr ...
DOI:: 10.1016/j.chroma.2008.01.088
: https://doi.org/10.1016/j.chroma.2008.01.088

10. Comparison of four extraction/methylation analytical methods to measure fatty acid composition by gas chromatography in meat

Author:: Juárez, M.; Polvillo, O.; Contò, M.; Ficco, A.; Ballico, S.; Failla, S.
Source:: Journal of chromatography 2008 v.1190 no.1-2 pp. 327-332
ISSN:: 0021-9673
Subject:: meat composition; food analysis; fatty acid composition; methylation; saponification; beef; extraction; polyunsaturated fatty acids
Abstract:: ... Four different extraction-derivatization methods commonly used for fatty acid analysis in meat (in situ or one-step method, saponification method, classic method and a combination of classic extraction and saponification derivatization) were tested. The in situ method had low recovery and variation. The saponification method showed the best balance between recovery, precision, repeatability and re ...
DOI:: 10.1016/j.chroma.2008.03.004
: https://doi.org/10.1016/j.chroma.2008.03.004

11. Design and synthesis of a novel fluorescent reagent, 6-oxy-(ethylpiperazine)-9-(2'-methoxycarbonyl) fluorescein, for carboxylic acids and its application in food samples using high-performance liquid chromatography

Author:: Du, Xiao-Lan; Zhang, Hua-Shan; Deng, Ying-Hua; Wang, Hong
Source:: Journal of chromatography 2008 v.1178 no.1-2 pp. 92-100
ISSN:: 0021-9673
Subject:: fatty acids; food analysis; soybean oil; chemical reactions; fluorescence; high performance liquid chromatography; fluorescein
Abstract:: ... A novel derivatization reagent for carboxylic acids, 6-oxy-(ethylpiperazine)-9-(2'-methoxycarbonyl)fluorescein (EPMF) has been well designed and synthesized. It was used to label 13 fatty acids, n-butyric acid (C4), n-valeric acid (C5), n-hexanoic acid (C6), n-heptanoic acid (C7), n-octanoic acid (C8), n-nonanoic acid (C9), n-decanoic acid (C10), lauric acid (C12), myristic acid (C14), palmitic ac ...
DOI:: 10.1016/j.chroma.2007.11.047
: https://doi.org/10.1016/j.chroma.2007.11.047

12. Determination of C₈₀ tetra-acid content in calcium naphthenate deposits

Author:: Simon, Sébastien; Nordgård, Erland; Bruheim, Per; Sjöblom, Johan
Source:: Journal of chromatography 2008 v.1200 no.2 pp. 136-143
ISSN:: 0021-9673
Subject:: calcium; derivatization; esters; naphthenates; oil fields; reversed-phase high performance liquid chromatography; solid phase extraction; toluene
Abstract:: ... A method is described which allows to determine the content of the so-called C₈₀ tetra-acid molecules (TA) in calcium naphthenate deposits. The method consists of four steps. Molecules present in the deposit are dissolved in a mixture of toluene and 2-butanol after an acidic treatment. All acid molecules are then selectively extracted and concentrated by a solid-phase extraction (SPE) method. Afte ...
DOI:: 10.1016/j.chroma.2008.05.091
: https://doi.org/10.1016/j.chroma.2008.05.091

13. Determination of basic degradation products of chemical warfare agents in water using hollow fibre-protected liquid-phase microextraction with in-situ derivatisation followed by gas chromatography-mass spectrometry

Author:: Lee, Hoi Sim Nancy; Sng, Mui Tiang; Basheer, Chanbasha; Lee, Hian Kee
Source:: Journal of chromatography 2008 v.1196-1197 pp. 125-132
ISSN:: 0021-9673
Subject:: derivatization; detection limit; mixing; nerve tissue; liquid-phase microextraction; pH; hydrophobicity; salt concentration; solid phase microextraction; solvents; gas chromatography-mass spectrometry
Abstract:: ... Hollow fibre-protected liquid-phase microextraction (HF-LPME) together with gas chromatography-mass spectrometry was, for the first time, investigated for the in-situ derivatisation and analysis of basic degradation products of chemical warfare agents in water samples. The degradation products studied were those of nerve and blister agents, and a psychotomimetic agent. Extractions with in-situ der ...
DOI:: 10.1016/j.chroma.2008.04.027
: https://doi.org/10.1016/j.chroma.2008.04.027

14. Determination of fatty alcohol ethoxylates by derivatisation with maleic anhydride followed by liquid chromatography with UV-vis detection

Author:: Micó-Tormos, A.; Collado-Soriano, C.; Torres-Lapasió, J.R.; Simó-Alfonso, E.; Ramis-Ramos, G.
Source:: Journal of chromatography 2008 v.1180 no.1-2 pp. 32-41
ISSN:: 0021-9673
Subject:: acetic acid; acetonitrile; algorithms; anhydrides; carbon; cleaning agents; derivatization; esterification; ethylene oxide; fatty alcohols; liquid chromatography; melting; rivers; seawater; solid phase extraction; temperature; urea
Abstract:: ... The esterification of fatty alcohol ethoxylates (FAEs) by melting with maleic anhydride has been studied in the presence of urea. The reaction rate and yield of non-ethoxylated and ethoxylated alcohols increase largely when grinded urea is suspended in the reaction medium, a 100% yield being achieved at 80°C in 15min. The procedure is tolerant to the presence of large amounts of water. The UV-vis ...
DOI:: 10.1016/j.chroma.2007.11.105
: https://doi.org/10.1016/j.chroma.2007.11.105

15. Determination of fatty alcohol ethoxylates by derivatization with phthalic anhydride followed by liquid chromatography with UV-vis detection

Author:: Micó-Tormos, A.; Simó-Alfonso, E.F.; Ramis-Ramos, G.
Source:: Journal of chromatography 2008 v.1203 no.1 pp. 47-53
ISSN:: 0021-9673
Subject:: acetic acid; acetonitrile; alcohols; cleaning agents; derivatization; esterification; ethylene oxide; liquid chromatography; phthalic anhydride; prediction; rivers; seawater; solid phase extraction; temperature; urea
Abstract:: ... The esterification of fatty alcohol ethoxylates (FAEs) with phthalic anhydride in 1,4-dioxane was studied. At 110°C and in the presence of urea, which increased the reaction rate, esterification was completed in 60min. The reaction yield did not decrease when the sample contained up to 50% water. For the non-ethoxylated alcohols, the UV-vis response factors of the derivatives were not significantl ...
DOI:: 10.1016/j.chroma.2008.07.017
: https://doi.org/10.1016/j.chroma.2008.07.017

16. Determination of galactose and mannose residues in natural galactomannans using a fast and efficient high-performance liquid chromatography/UV detection

Author:: Tapie, N.; Malhiac, C.; Hucher, N.; Grisel, M.
Source:: Journal of chromatography 2008 v.1181 no.1-2 pp. 45-50
ISSN:: 0021-9673
Subject:: acid hydrolysis; derivatization; galactomannans; galactose; mannose; quantitative analysis; reversed-phase high performance liquid chromatography
Abstract:: ... The present work describes the validation of an easy, fast and efficient precolumn derivatization method for the quantification of oligosides, mannose and galactose obtained by degradation of galactomannans. This work combines an acid hydrolysis and an enzymatic degradation of natural galactomannans with the quantification of released residues by reversed-phase HPLC-UV, the most usual HPLC system ...
DOI:: 10.1016/j.chroma.2007.12.027
PubMed:: 18177885
: https://doi.org/10.1016/j.chroma.2007.12.027

17. Determination of phenols and chlorophenols as trimethylsilyl derivatives using gas chromatography-mass spectrometry

Author:: Kovács, Ágnes; Kende, Anikó; Mörtl, Mária; Volk, Gábor; Rikker, Tamás; Torkos, Kornél
Source:: Journal of chromatography 2008 v.1194 no.1 pp. 139-142
ISSN:: 0021-9673
Subject:: derivatization; detection limit; pentachlorophenol; p-cresol; phenol; isomers; chlorophenols; catechol; temperature; resorcinol; solid phase extraction; gas chromatography-mass spectrometry
Abstract:: ... A rapid and simple method is described for the simultaneous determination of 6 phenols (phenol, o-, m-, p-cresol, catechol and resorcinol) and 19 chlorophenols (all mono-, di-, tri-, and tetrachlorophenol isomers and pentachlorophenol) present in aqueous samples. The method is based on derivatization with trimethylsilyl-N,N-dimethylcarbamate (TMSDMC). In contrast to other derivatization agents, TM ...
DOI:: 10.1016/j.chroma.2008.04.043
: https://doi.org/10.1016/j.chroma.2008.04.043

18. Determination of the carbon isotopic composition of whole/intact biological specimens using at-line direct thermal desorption to effect thermally assisted hydrolysis/methylation

Author:: Akoto, Lawrence; Vreuls, René J.J.; Irth, Hubertus; Floris, Virgilio; Hoogveld, Hans; Pel, Roel
Source:: Journal of chromatography 2008 v.1186 no.1-2 pp. 372-379
ISSN:: 0021-9673
Subject:: automation; carbon; chromatography; derivatization; desorption; evaporation; fatty acid methyl esters; fatty acids; flow cytometry; glyphosate-trimesium; hydrolysis; mass spectrometry; methylation; microalgae; phytoplankton; pyrolysis; solvents; zooplankton
Abstract:: ... In this paper, we discuss the use of a direct thermal desorption (DTD) interface as an alternative to Curie-point flash pyrolysis system as an inlet technique in gas chromatography-combustion isotope-ratio mass spectrometry (GC/C-IRMS) analysis of whole/intact phytoplankton and zooplankton specimens. The DTD in combination with a combipal auto-injector is programmed to perform the injection, evapo ...
DOI:: 10.1016/j.chroma.2007.08.082
: https://doi.org/10.1016/j.chroma.2007.08.082

19. Determination of γ-hydroxybutyric acid in clinical samples using capillary electrophoresis with contactless conductivity detection

Author:: Gong, Xiao Yang; Kubáň, Pavel; Scholer, André; Hauser, Peter C.
Source:: Journal of chromatography 2008 v.1213 no.1 pp. 100-104
ISSN:: 0021-9673
Subject:: 3-hydroxybutyric acid; arginine; blood serum; capillary electrophoresis; cetyltrimethylammonium bromide; chromatography; derivatization; detection limit; maleic acid; urine; vancomycin
Abstract:: ... A method for the determination of γ-hydroxybutyric acid (GHB) in urine and serum samples with capillary electrophoresis using capacitively coupled contactless conductivity detection (CE-C⁴D) was developed. The optimized separation buffer consisting of 20mM of arginine, 10mM of maleic acid and 30μM of cetyltrimethylammonium bromide (CTAB) contained 5mM vancomycin to facilitate the separation of γ-h ...
DOI:: 10.1016/j.chroma.2008.10.015
: https://doi.org/10.1016/j.chroma.2008.10.015

20. Development of C₁₈-functionalized magnetic silica nanoparticles as sample preparation technique for the determination of ergosterol in cigarettes by microwave-assisted derivatization and gas chromatography/mass spectrometry

Author:: Sha, Yunfei; Deng, Chunhui; Liu, Baizhan
Source:: Journal of chromatography 2008 v.1198-1199 pp. 27-33
ISSN:: 0021-9673
Subject:: aromatic hydrocarbons; cigarettes; derivatization; detection limit; ergosterol; fungi; gas chromatography; magnetism; mass spectrometry; microwave treatment; nanoparticles; silica; surface area; temperature
Abstract:: ... Ergosterol is one of the important precursors of tumorigenic polynuclear aromatic hydrocarbons. A large amount of ergosterol is present in mildewy cigarettes, which derives from fungal contaminations. In this paper, a novel approach based on C₁₈-functionalized magnetic silica nanoparticles (C₁₈-f-MS NPs) coupled with microwave-assisted derivatization and gas chromatography/mass spectrometry (GC/MS ...
DOI:: 10.1016/j.chroma.2008.05.049
: https://doi.org/10.1016/j.chroma.2008.05.049

21. Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids

Author:: Yamashita, Kouwa; Okuyama, Mitsunobu; Nakagawa, Risa; Honma, Seijiro; Satoh, Fumitoshi; Morimoto, Ryo; Ito, Sadayoshi; Takahashi, Madoka; Numazawa, Mitsuteru
Source:: Journal of chromatography 2008 v.1200 no.2 pp. 114-121
ISSN:: 0021-9673
Subject:: aldosterone; blood serum; chromatography; corticosterone; derivatization; esterification; ionization; monitoring; picolinic acid; tandem mass spectrometry
Abstract:: ... A highly sensitive quantification method of aldosterone by liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) was investigated in a positive mode using recently developed picolinyl derivatization. Aldosterone was smoothly and quantitatively converted to the ethyl ether-picolinyl derivative by treatment with HCl-ethanol followed by the esterification with picolini ...
DOI:: 10.1016/j.chroma.2008.05.034
: https://doi.org/10.1016/j.chroma.2008.05.034

22. Direct quantification of steroid glucuronides in human urine by liquid chromatography-electrospray tandem mass spectrometry

Author:: Pozo, Oscar J.; Van Eenoo, Peter; Van Thuyne, Wim; Deventer, Koen; Delbeke, Frans T.
Source:: Journal of chromatography 2008 v.1183 no.1-2 pp. 108-118
ISSN:: 0021-9673
Subject:: correlation; derivatization; detection limit; urine; androsterone; humans; ionization; liquid-liquid extraction; tandem mass spectrometry; filtration; hydrolysis; ethyl acetate; liquid chromatography; testosterone; gas chromatography-mass spectrometry
Abstract:: ... A method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the direct quantification of glucuronides of testosterone (TG), epitestosterone (EPG), androsterone (AG) and etiocholanolone (ETG) has been developed. The method allowed for the direct determination of these analytes avoiding hydrolysis and derivatization, which are usual steps in commonly used methods based on gas chr ...
DOI:: 10.1016/j.chroma.2008.01.045
: https://doi.org/10.1016/j.chroma.2008.01.045

23. Dynamic ultrasound-assisted extraction coupled on-line with solid support derivatization and high-performance liquid chromatography for the determination of formaldehyde in textiles

Author:: Chen, Ligang; Jin, Haiyan; Wang, Liguang; Sun, Lei; Xu, Haoyan; Ding, Lan; Yu, Aimin; Zhang, Hanqi
Source:: Journal of chromatography 2008 v.1192 no.1 pp. 89-94
ISSN:: 0021-9673
Subject:: cation exchange; derivatization; detection limit; fabrics; formaldehyde; high performance liquid chromatography; spectroscopy; ultrasonics; water flow; China
Abstract:: ... An on-line method was developed for the extraction, derivatization and determination of formaldehyde in textile samples. Formaldehyde was first extracted with water by ultrasound assisted, and directly introduced into a derivatization column which was packed with a moderately sulfonated cation-exchange resin. The resin used as solid support for the derivatization was charged with 2,4-dinitrophenyl ...
DOI:: 10.1016/j.chroma.2008.03.037
: https://doi.org/10.1016/j.chroma.2008.03.037

24. Enantioselective gas chromatographic analysis of aqueous samples by on-line derivatisation

Author:: Mommers, John H.M.; de Wildeman, Stefaan M.A.; Koolen, Wilma A.F.; Duchateau, Alexander L.L.
Source:: Journal of chromatography 2008 v.1182 no.2 pp. 215-218
ISSN:: 0021-9673
Subject:: alcohol dehydrogenase; alcohols; derivatization; enzymatic reactions; gas chromatography
Abstract:: ... A new gas chromatography (GC) method is presented for analysing both the conversion and the enantiomeric excess (e.e.) of samples from alcohol dehydrogenase reactions. The chiral compounds studied were a series of saturated, straight chain alcohols, ranging from 2-butanol to 2-heptanol. The alcohols were converted to the corresponding trifluoroacetylated derivatives by injecting trifluoroacetic an ...
DOI:: 10.1016/j.chroma.2007.12.069
: https://doi.org/10.1016/j.chroma.2007.12.069

25. Enhancing sensitivity of liquid chromatographic/ion-trap tandem mass spectrometric determination of estrogens by on-line pre-column derivatization

Author:: Matějíček, David; Kubáň, Vlastimil
Source:: Journal of chromatography 2008 v.1192 no.2 pp. 248-253
ISSN:: 0021-9673
Subject:: chromatography; derivatization; detection limit; estriol; estrone; mass spectrometry; river water; solid phase extraction
Abstract:: ... A rapid and sensitive liquid chromatographic/ion-trap mass spectrometric method has been developed for the simultaneous determination of estriol, α-, β-estradiol, 17α-ethynylestradiol and estrone. The substances were extracted from river water samples (typically 250ml) and cleaned-up using two-stage solid-phase extraction (SPE). 12-(Difluoro-1,3,5-triazinyl)-benz[f]isoindolo-[1,2b][1,3]benzothiazo ...
DOI:: 10.1016/j.chroma.2008.03.061
: https://doi.org/10.1016/j.chroma.2008.03.061

26. Evaluation of solid-phase microextraction methods for determination of trace concentration aldehydes in aqueous solution

Author:: Beránek, Josef; Kubátová, Alena
Source:: Journal of chromatography 2008 v.1209 no.1-2 pp. 44-54
ISSN:: 0021-9673
Subject:: United States Environmental Protection Agency; aqueous solutions; chromatography; derivatization; detection limit; formaldehyde; headspace analysis; particulates; solid phase microextraction; temperature; United States
Abstract:: ... A method for trace analysis of a wide range of aldehydes (saturated/unsaturated aliphatic, aromatic aldehydes, including hydroxylated species, and dialdehydes) in an aqueous solution was optimized. An evaluation of three solid-phase microextraction (SPME) techniques (headspace, liquid-phase, and on-fiber derivatization) with o-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA) aldehy ...
DOI:: 10.1016/j.chroma.2008.09.013
: https://doi.org/10.1016/j.chroma.2008.09.013

27. Evaluation of various derivatization approaches for gas chromatography-mass spectrometry analysis of buprenorphine and norbuprenorphine

Author:: Wu, Chih-Hung; Yang, Shu-Ching; Wang, Yu-Shan; Chen, Bud-Gen; Lin, Ching-Chiang; Liu, Ray H.
Source:: Journal of chromatography 2008 v.1182 no.1 pp. 93-112
ISSN:: 0021-9673
Subject:: derivatization; ions; ionization; metabolites; acylation; buprenorphine; alkylation; gas chromatography-mass spectrometry
Abstract:: ... Various chemical derivatization approaches have been adapted for the analysis of buprenorphine and its major metabolite (norbuprenorphine) by GC-MS based methodologies. These approaches included alkylation, acylation, and silylation resulting in the formation of methyl, acetyl, trifluoroacetyl, pentafluoropropionyl, heptafluorobutyryl, and trimethylsilyl derivatives. This study conducted a compreh ...
DOI:: 10.1016/j.chroma.2007.11.063
: https://doi.org/10.1016/j.chroma.2007.11.063

28. Extending the molecular application range of gas chromatography

Author:: Kaal, Erwin; Janssen, Hans-Gerd
Source:: Journal of chromatography 2008 v.1184 no.1-2 pp. 43-60
ISSN:: 0021-9673
Subject:: derivatization; gas chromatography; mass spectrometry; metabolomics; pyrolysis; quantitative analysis
Abstract:: ... Gas chromatography is an important analytical technique for qualitative and quantitative analysis in a wide range of application areas. It is fast, provides a high peak capacity, is sensitive and allows combination with a wide range of selective detection methods including mass spectrometry. However, the application area of GC is limited because the molecules to be analysed have to be thermally st ...
DOI:: 10.1016/j.chroma.2007.11.114
: https://doi.org/10.1016/j.chroma.2007.11.114

29. Field analysis of acetaldehyde in mainstream tobacco smoke using solid-phase microextraction and a portable gas chromatograph

Author:: Lin, Huaqing; Ye, Qing; Deng, Chunhui; Zhang, Xiangmin
Source:: Journal of chromatography 2008 v.1198-1199 pp. 34-37
ISSN:: 0021-9673
Subject:: acetaldehyde; additives; animals; carbohydrates; carcinogens; cytotoxicity; derivatization; detection limit; gas chromatography; headspace analysis; mixing; oximes; paper; pyrolysis; rapid methods; smoking (habit); solid phase microextraction; tobacco
Abstract:: ... Acetaldehyde is generated in the mainstream tobacco smoke mainly from the pyrolysis (and oxidative pyrolysis) of carbohydrates that are present in tobacco plant, cigarette paper, and also used as additives in tobacco. Acetaldehyde has been classified as an animal carcinogen, and may be cytotoxic or genetoxic. Owing to its high volatility and reactivity, it is difficult to accurately measure it, es ...
DOI:: 10.1016/j.chroma.2008.05.050
: https://doi.org/10.1016/j.chroma.2008.05.050

30. Fluoroalkyl chloroformates in treating amino acids for gas chromatographic analysis

Author:: Hušek, Petr; Šimek, Petr; Hartvich, Petr; Zahradníčková, Helena
Source:: Journal of chromatography 2008 v.1186 no.1-2 pp. 391-400
ISSN:: 0021-9673
Subject:: carbon; catalysts; derivatization; detection limit; flame ionization; glutamic acid; histidine; hydrophobicity; ions; iso-octanes; mass spectrometry; proline; pyridines
Abstract:: ... Novel fluoroalkyl chloroformates with three and four carbon atoms were investigated for the immediate conversion of amino acids into hydrophobic derivatives in water-containing media. Derivatization conditions were extensively studied and optimized sample preparation protocols elaborated. More than 30 amino acids were treated with the particular reagent in isooctane by simply vortexing the reactiv ...
DOI:: 10.1016/j.chroma.2007.11.117
: https://doi.org/10.1016/j.chroma.2007.11.117

31. Gas chromatography-mass spectrometry of the trimethylsilyl (oxime) ether/ester derivatives of cholic acids: Their presence in the aquatic environment

Author:: Sebők, Á.; Sezer, K.; Vasanits-Zsigrai, A.; Helenkár, A.; Záray, Gy.; Molnár-Perl, I.
Source:: Journal of chromatography 2008 v.1211 no.1-2 pp. 104-112
ISSN:: 0021-9673
Subject:: derivatization; rivers; ions; cholic acid; aquatic environment; pollutants; hydrochloric acid; pH; temperature; wastewater; solid phase extraction; gas chromatography-mass spectrometry
Abstract:: ... This paper presents a derivatization, mass fragmentation study relating to the most common six cholic acids, such as cholic, lithocholic, chenodeoxycholic, ursodeoxycholic, 3-hydroxy,7-ketocholanic and dehydrocholic acids, identified and quantified as pollutants in the aquatic environment at the first time. Derivatizations have been performed with the two-step process (1: oximation, 2: silylation) ...
DOI:: 10.1016/j.chroma.2008.09.079
: https://doi.org/10.1016/j.chroma.2008.09.079

32. Gradient elution isotachophoresis with direct ultraviolet absorption detection for sensitive amino acid analysis

Author:: Mamunooru, Manasa; Jenkins, Ronald J.; Davis, Nejea I.; Shackman, Jonathan G.
Source:: Journal of chromatography 2008 v.1202 no.2 pp. 203-211
ISSN:: 0021-9673
Subject:: absorbance; absorption; amino acid composition; cerebrospinal fluid; chromatography; derivatization; detection limit; electric field; electrolytes; electrophoresis; fluorescence; monitoring; tryptophan; tyrosine
Abstract:: ... This work demonstrates coupling of the newly described electrophoretic enrichment technique of gradient elution isotachophoresis (GEITP) to a low-cost, conventional ultraviolet absorbance detector to realize sensitive measurements with a universal detector, eliminating the need for fluorescent analytes or derivatization. The effects of various parameters on enrichment were studied, including curre ...
DOI:: 10.1016/j.chroma.2008.07.005
: https://doi.org/10.1016/j.chroma.2008.07.005

33. Highly sensitive detection of pharmaceutical compounds in biological fluids using capillary electrophoresis coupled with laser-induced native fluorescence

Author:: Schappler, Julie; Staub, Aline; Veuthey, Jean-Luc; Rudaz, Serge
Source:: Journal of chromatography 2008 v.1204 no.2 pp. 183-190
ISSN:: 0021-9673
Subject:: biochemical compounds; capillary electrophoresis; chromatography; derivatization; drugs; experimental design; fluorescence; forensic sciences; propranolol; rapid methods
Abstract:: ... Due to its selectivity and sensitivity, capillary electrophoresis coupled to laser-induced fluorescence has evolved as a useful analytical tool for determining drugs in biological samples. This paper describes a simple, sensitive, efficient, and rapid method for analyzing propranolol without derivatization in plasma by CE-LIF using a diode solid-state laser at 266nm. An experimental design methodo ...
DOI:: 10.1016/j.chroma.2008.04.044
: https://doi.org/10.1016/j.chroma.2008.04.044

34. Hydroxyproline quantification for the estimation of collagen in tissue using multiple reaction monitoring mass spectrometry

Author:: Colgrave, Michelle L.; Allingham, Peter G.; Jones, Alun
Source:: Journal of chromatography 2008 v.1212 no.1-2 pp. 150-153
ISSN:: 0021-9673
Subject:: chromatography; collagen; derivatization; hydroxyproline; mammals; mass spectrometry; monitoring; muscles
Abstract:: ... Collagens are highly abundant mammalian proteins that contain a high content of hydroxylated amino acids such as hydroxyproline. We have exploited the high hydroxyproline content of collagen and developed a method for hydroxyproline quantification as a measure of collagen content in muscle samples. The novel method utilizes a highly selective and sensitive method of multiple reaction monitoring (M ...
DOI:: 10.1016/j.chroma.2008.10.011
: https://doi.org/10.1016/j.chroma.2008.10.011

35. In-capillary derivatization and analysis of ephedrine and pseudoephedrine by micellar electrokinetic chromatography with laser-induced fluorescence detection

Author:: Zhou, Lei; Zhou, Ximin; Luo, Zhi; Wang, Weiping; Yan, Na; Hu, Zhide
Source:: Journal of chromatography 2008 v.1190 no.1-2 pp. 383-389
ISSN:: 0021-9673
Subject:: alkaloids; derivatization; detection limit; ephedrine; fluorescence; micellar electrokinetic capillary chromatography; mixing; pseudoephedrine
Abstract:: ... This paper describes an automatic rapid approach for in-capillary derivatization of ephedrine (E) and pseudoephedrine (PE) and subsequent sensitive determination of the derivatives by micellar electrokinetic chromatography (MEKC) with laser-induced fluorescence (LIF) detection using 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) as fluorescent reagent. The unique feature of this method is the capil ...
DOI:: 10.1016/j.chroma.2008.03.024
: https://doi.org/10.1016/j.chroma.2008.03.024

36. In-capillary derivatization and capillary electrophoresis separation of amino acid neurotransmitters from brain microdialysis samples

Author:: Denoroy, Luc; Parrot, Sandrine; Renaud, Louis; Renaud, Bernard; Zimmer, Luc
Source:: Journal of chromatography 2008 v.1205 no.1-2 pp. 144-149
ISSN:: 0021-9673
Subject:: amino acid composition; amino acids; brain; capillary electrophoresis; chromatography; derivatization; fluorescence; microdialysis; mixing; neurotransmitters; rats
Abstract:: ... A new in-capillary derivatization method with naphtalene-2,3-dicarboxyaldehyde (NDA)/CN⁻ has been developed for capillary electrophoresis with laser-induced fluorescence detection of brain microdialysate amino acids. Samples are sandwiched between two plugs of reagent mixture at the capillary inlet and subsequently separated. Highest derivatization yields are obtained by using a reagent to sample ...
DOI:: 10.1016/j.chroma.2008.07.043
: https://doi.org/10.1016/j.chroma.2008.07.043

37. Indirect enantioseparation of α-amino acids by reversed-phase liquid chromatography using new chiral derivatizing reagents synthesized from s-triazine chloride

Author:: Bhushan, Ravi; Kumar, Virender
Source:: Journal of chromatography 2008 v.1201 no.1 pp. 35-42
ISSN:: 0021-9673
Subject:: acetonitrile; acids; amides; amino acids; chlorine; derivatization; detection limit; diastereomers; pH; reversed-phase liquid chromatography; temperature
Abstract:: ... Ten chiral dichloro- and monochloro-s-triazines were prepared by the nucleophilic displacement of chlorine atom(s) in s-triazine chloride and its 6-methoxy derivative with different amino acid amides. Dichloro-s-triazines (DCTs) were used as CDRs for derivatization of α-amino acids under basic conditions at room temperature (30°C) while derivatization with monochloro-s-traizine (MCT) reagents was ...
DOI:: 10.1016/j.chroma.2008.05.087
: https://doi.org/10.1016/j.chroma.2008.05.087

38. Ion-pair single-drop microextraction versus phase-transfer catalytic extraction for the gas chromatographic determination of phenols as tosylated derivatives

Author:: Fiamegos, Yiannis C.; Kefala, Ageliki-Panayota; Stalikas, Constantine D.
Source:: Journal of chromatography 2008 v.1190 no.1-2 pp. 44-51
ISSN:: 0021-9673
Subject:: derivatization; detection limit; environmental fate; gas chromatography; liquid-liquid extraction; mass spectrometry; microextraction; monitoring; phenols; physicochemical properties; solvents; temperature; toxicity
Abstract:: ... The environmental fate of phenols represents a diachronic scientific consideration mainly due to their high toxicity and diverse physicochemical properties rendering them difficult to be analyzed as unity. Ion-pair-assisted extraction and microextraction techniques in association with a dedicated derivatization reaction are possible to lead to enhanced selectivity and sensitivity in gas chromatogr ...
DOI:: 10.1016/j.chroma.2008.03.010
: https://doi.org/10.1016/j.chroma.2008.03.010

39. Liquid chromatographic resolution of vigabatrin and its analogue γ-amino acids on chiral stationary phases based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid

Author:: Lee, Su Jin; Cho, Hwan Sun; Choi, Hee Jung; Hyun, Myung Ho
Source:: Journal of chromatography 2008 v.1188 no.2 pp. 318-321
ISSN:: 0021-9673
Subject:: acids; anticonvulsants; chromatography; derivatization; epilepsy
Abstract:: ... Racemic vigabatrin, an anticonvulsant drug used for the treatment of epilepsy, and its analogue γ-amino acids were resolved without derivatization on liquid chromatographic chiral stationary phases (CSPs) based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid. Between the two CSPs which contain 3 methylene-unit or 11 methylene-unit spacer group, the latter was found to be greater than the former ...
DOI:: 10.1016/j.chroma.2008.02.102
: https://doi.org/10.1016/j.chroma.2008.02.102

40. Mercury speciation and analysis in drinking water by stir bar sorptive extraction with in situ propyl derivatization and thermal desorption-gas chromatography-mass spectrometry

Author:: Ito, Rie; Kawaguchi, Migaku; Sakui, Norihiro; Honda, Hidehiro; Okanouchi, Noriya; Saito, Koichi; Nakazawa, Hiroyuki
Source:: Journal of chromatography 2008 v.1209 no.1-2 pp. 267-270
ISSN:: 0021-9673
Subject:: bottled water; chromatography; correlation; derivatization; desorption; detection limit; mass spectrometry; mercury; methylmercury compounds; pH; tap water
Abstract:: ... A method for mercury analysis and speciation in drinking water was developed, which involved stir bar sorptive extraction (SBSE) with in situ propyl derivatization and thermal desorption (TD)-GC-MS. Ten millilitre of tap water or bottled water was used. After a stir bar, pH adjustment agent and derivatization reagent were added, SBSE was performed. Then, the stir bar was subjected to TD-GC-MS. The ...
DOI:: 10.1016/j.chroma.2008.09.037
: https://doi.org/10.1016/j.chroma.2008.09.037

41. Multivariate optimization approach for the analysis of butyltin compounds in mussel tissues by gas chromatography-mass spectrometry

Author:: Magi, Emanuele; Liscio, Camilla; Di Carro, Marina
Source:: Journal of chromatography 2008 v.1210 no.1 pp. 99-107
ISSN:: 0021-9673
Subject:: derivatization; acetates; mussels; tributyltin; pH; gills; Mytilus galloprovincialis; solid phase extraction; tissues; gas chromatography-mass spectrometry
Abstract:: ... The derivatization with NaBEt₄ for the determination of butyltin compounds in mussel tissues (Mytilus galloprovincialis) by GC-MS was optimized using a central composite design. The effects of NaBEt₄ concentration, pH and acetate buffer concentration on the derivatization efficiency were considered. Solid-phase extraction with Florisil cartridges was performed, demonstrating that the clean-up dras ...
DOI:: 10.1016/j.chroma.2008.09.045
: https://doi.org/10.1016/j.chroma.2008.09.045

42. Multivariate optimization of a derivatisation procedure for the simultaneous determination of nine anabolic steroids by gas chromatography coupled with mass spectrometry

Author:: Hadef, Y.; Kaloustian, J.; Portugal, H.; Nicolay, A.
Source:: Journal of chromatography 2008 v.1190 no.1-2 pp. 278-285
ISSN:: 0021-9673
Subject:: androsterone; beta-mercaptoethanol; derivatization; estradiol; gas chromatography; iodides; mass spectrometry; models; nandrolone; propionic acid; response surface methodology; temperature; testosterone
Abstract:: ... The medical commission of the International Olympic Committee forbids the use of anabolic androgenic steroids to improve sporting performances. Nine anabolic steroids (androsterone (A), nandrolone, estradiol, testosterone propionate, nandrolone-17 propionate, dydrogesterone, testosterone, epitestosterone, boldenone) and α-cholestane as internal standard were studied by gas chromatography coupled w ...
DOI:: 10.1016/j.chroma.2008.02.100
: https://doi.org/10.1016/j.chroma.2008.02.100

43. On-column electrochemical redox derivatization for enhancement of separation selectivity of liquid chromatography

Author:: Saitoh, Kazunori; Koichi, Kohta; Yabiku, Fumiko; Noda, Yumiko; Porter, Marc D.; Shibukawa, Masami
Source:: Journal of chromatography 2008 v.1180 no.1-2 pp. 66-72
ISSN:: 0021-9673
Subject:: benzoquinones; catechol; derivatization; electrochemistry; electrodes; graphene; high performance liquid chromatography; hydroquinone; packaging materials; porous media; redox reactions
Abstract:: ... An on-column electrochemical redox derivatization for enhancement of high-performance liquid chromatography (HPLC) separation selectivity is presented using electrochemically modulated liquid chromatography (EMLC) and porous graphitic carbon (PGC) as the packing material. PGC therefore serves two purposes: it acts both as a chromatographic stationary phase and as a working electrode. The capabilit ...
DOI:: 10.1016/j.chroma.2007.12.003
: https://doi.org/10.1016/j.chroma.2007.12.003

44. Purge-assisted headspace solid-phase microextraction combined with gas chromatography-mass spectrometry for determination of chlorophenols in aqueous samples

Author:: Ho, Hsin-Pin; Lee, Ren-Jye; Lee, Maw-Rong
Source:: Journal of chromatography 2008 v.1213 no.2 pp. 245-248
ISSN:: 0021-9673
Subject:: derivatization; detection limit; pentachlorophenol; headspace analysis; landfill leachates; 2,4-dichlorophenol; solid phase microextraction; vapor pressure; temperature; gas chromatography-mass spectrometry
Abstract:: ... A simple, economical and very effective method is demonstrated for simultaneous determination of 2,4-dichlorophenol, 2,4,6-trichlorophenol, 2,3,4,6-tetrachlorophenol and pentachlorophenol, in aqueous samples, by using purge-assisted headspace solid-phase microextraction (PA/HS-SPME) coupled to gas chromatography-mass spectrometry (GC-MS). In the new method, purging the sample enhances the removal ...
DOI:: 10.1016/j.chroma.2008.10.056
: https://doi.org/10.1016/j.chroma.2008.10.056

45. Quantification of N-acetyl- and N-glycolylneuraminic acids by a stable isotope dilution assay using high-performance liquid chromatography-tandem mass spectrometry

Author:: Allevi, Pietro; Femia, Eti Alessandra; Costa, Maria Letizia; Cazzola, Roberta; Anastasia, Mario
Source:: Journal of chromatography 2008 v.1212 no.1-2 pp. 98-105
ISSN:: 0021-9673
Subject:: correlation; derivatization; fetuins; glycoproteins; isotope dilution technique; liquid chromatography; models; quantitative analysis; sialic acids; stable isotopes; tandem mass spectrometry
Abstract:: ... The present report describes a method for the quantification of N-acetyl- and N-glycolylneuraminic acids without any derivatization, using their ¹³C₃-isotopologues as internal standards and a C₁₈ reversed-phase column modified by decylboronic acid which allows for the first time a complete chromatographic separation between the two analytes. The method is based on high-performance liquid chromatog ...
DOI:: 10.1016/j.chroma.2008.10.039
: https://doi.org/10.1016/j.chroma.2008.10.039

46. Rapid screening of methamphetamines in human serum by headspace solid-phase microextraction using a dodecylsulfate-doped polypyrrole film coupled to ion mobility spectrometry

Author:: Alizadeh, Naader; Mohammadi, Abdorreza; Tabrizchi, Mahmoud
Source:: Journal of chromatography 2008 v.1183 no.1-2 pp. 21-28
ISSN:: 0021-9673
Subject:: blood serum; chromatography; coatings; derivatization; desorption; detection limit; electrochemistry; headspace analysis; humans; ionic strength; pH; platinum; rapid methods; screening; solid phase microextraction; spectroscopy; temperature
Abstract:: ... A simple, rapid and highly sensitive method for simultaneous analysis of methamphetamine (MA) and 3,4-methylenedioxy methamphetamine (MDMA) in human serum was developed using the solid-phase microextraction (SPME) combined with ion mobility spectrometry (IMS). A dodecylsulfate-doped polypyrrole (PPy-DS) was applied as a new fiber for SPME. Electrochemically polymerized PPy is formed on the surface ...
DOI:: 10.1016/j.chroma.2008.01.020
: https://doi.org/10.1016/j.chroma.2008.01.020

47. Relative efficiency of free fatty acid butyl esterification

Author:: Hallmann, Christian; van Aarssen, Ben G.K.; Grice, Kliti
Source:: Journal of chromatography 2008 v.1198-1199 pp. 14-20
ISSN:: 0021-9673
Subject:: boron; carboxylic acids; catalysts; chromatography; derivatization; esterification; esters; free fatty acids; quantitative analysis; sulfuric acid; temperature
Abstract:: ... The conversion efficiency of alkanoic, alkenoic, branched, alicyclic, aromatic, keto-substituted, and dioic carboxylic acids to their corresponding butyl esters was compared under different reaction conditions (time, temperature, catalyst). We show that boron trifluoride is generally a more efficient catalyst than sulphuric acid. However, optimum derivatisation conditions vary strongly for differe ...
DOI:: 10.1016/j.chroma.2008.05.030
: https://doi.org/10.1016/j.chroma.2008.05.030

48. Separation of amino acid enantiomers VIA chiral derivatization and non-chiral gas chromatography

Author:: Bertrand, Marylène; Chabin, Annie; Brack, André; Westall, Frances
Source:: Journal of chromatography 2008 v.1180 no.1-2 pp. 131-137
ISSN:: 0021-9673
Subject:: amino acids; capillary gas chromatography; derivatization; diastereomers; enantiomers; separation
Abstract:: ... Two GC-MS methods for the enantioselective separation of the 20 proteinogenic amino acids are compared. Ethyl chloroformate and 2-chloropropanol were used to derivatize amino acid enantiomers. The diastereomers formed were separated on a non-chiral column by capillary gas chromatography. The separation performances were compared to those obtained when using non-chiral derivatization on a chiral co ...
DOI:: 10.1016/j.chroma.2007.12.004
: https://doi.org/10.1016/j.chroma.2007.12.004

49. Simultaneous analysis of benzophenone sunscreen compounds in water sample by stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography-mass spectrometry

Author:: Kawaguchi, Migaku; Ito, Rie; Honda, Hidehiro; Endo, Naoyuki; Okanouchi, Noriya; Saito, Koichi; Seto, Yasuo; Nakazawa, Hiroyuki
Source:: Journal of chromatography 2008 v.1200 no.2 pp. 260-263
ISSN:: 0021-9673
Subject:: benzophenones; correlation; derivatization; detection limit; river water; mass spectrometry; gas chromatography; desorption
Abstract:: ... A method for the simultaneous measurement of benzophenone (BP) sunscreen compounds, its derivatives 2,4-dihydroxybenzophenone (BP-1), 2-hydroxy-4-methoxybenzophenone (BP-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone (BP-10), 2-hydroxybenzophenone (2OH-BP), 3-hydroxybenzophenone (3OH-BP) and 4-hydroxybenzophenone (4OH-BP), in water samples was developed using stir bar sorptive extraction (SBSE) wit ...
DOI:: 10.1016/j.chroma.2008.05.084
: https://doi.org/10.1016/j.chroma.2008.05.084

50. Simultaneous derivatization and extraction of amphetamine and methylenedioxyamphetamine in urine with headspace liquid-phase microextraction followed by gas chromatography-mass spectrometry

Author:: Chiang, Jing-Shan; Huang, Shang-Da
Source:: Journal of chromatography 2008 v.1185 no.1 pp. 19-22
ISSN:: 0021-9673
Subject:: derivatization; urine; humans; monitoring; headspace analysis; amphetamine; liquid-phase microextraction; solvents; gas chromatography-mass spectrometry
Abstract:: ... A new method is reported for the simultaneous extraction and derivatization of amphetamine (AM) and methylenedioxyamphetamine (MDA) using headspace hollow fiber protected liquid-phase microextraction (HS-HF-LPME); quantitation is by gas chromatograph-mass spectrometry in the selected ion monitoring (SIM) mode. The derivatizing reagent, pentafluorobenzaldehyde (PFBAY), was added to the extraction s ...
DOI:: 10.1016/j.chroma.2008.01.038
: https://doi.org/10.1016/j.chroma.2008.01.038

51. Simultaneous determination of derivatized light aldehydes by microchip electrophoresis with electrochemical detection

Author:: Dossi, Nicolò; Susmel, Sabina; Toniolo, Rosanna; Pizzariello, Andrea; Bontempelli, Gino
Source:: Journal of chromatography 2008 v.1207 no.1-2 pp. 169-174
ISSN:: 0021-9673
Subject:: acetaldehyde; acetonitrile; carbon; chromatography; derivatization; detection limit; electrochemistry; electrodes; electrophoresis; pH; sodium dodecyl sulfate; vegetable oil
Abstract:: ... A method, based on microchip electrophoresis with electrochemical detection, has been developed for the simultaneous determination of light aliphatic aldehydes (acetaldehyde, propionaldehyde, butyraldehyde and hexylaldehyde) derivatized with 2,4-dinitrophenylhydrazine (DNPH). Optimal conditions for the derivatization reaction, providing recoveries of 70±1.8% for all analytes, were identified by ap ...
DOI:: 10.1016/j.chroma.2008.08.016
: https://doi.org/10.1016/j.chroma.2008.08.016

52. Simultaneous liquid-liquid microextraction/methylation for the determination of haloacetic acids in drinking waters by headspace gas chromatography

Author:: Cardador, M.J.; Serrano, A.; Gallego, M.
Source:: Journal of chromatography 2008 v.1209 no.1-2 pp. 61-69
ISSN:: 0021-9673
Subject:: temperature; mass transfer; derivatization; detection limit; drinking; United States Environmental Protection Agency; methylation; headspace analysis; models; decarboxylation; catalysts; swimming; liquid-phase microextraction; esters; haloacetic acids; drinking water; gas chromatography-mass spectrometry; United States
Abstract:: ... A novel analytical method that combines simultaneous liquid-liquid microextraction/methylation and headspace gas chromatography-mass spectrometry for the determination of nine haloacetic acids (HAAs) in water was reported. A mechanistic model on the basis of mass transfer with chemical reaction in which methylation of HAAs was accomplished in n-pentane-water (150μl-10ml) two-phase system with a te ...
DOI:: 10.1016/j.chroma.2008.09.033
: https://doi.org/10.1016/j.chroma.2008.09.033

53. Simultaneous speciation of methylmercury and butyltin species in environmental samples by headspace-stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry

Author:: Prieto, A.; Zuloaga, O.; Usobiaga, A.; Etxebarria, N.; Fernández, L.A.; Marcic, C.; de Diego, A.
Source:: Journal of chromatography 2008 v.1185 no.1 pp. 130-138
ISSN:: 0021-9673
Subject:: sediments; derivatization; potassium hydroxide; methanol; experimental design; mercury; headspace analysis; hydrochloric acid; salting; methylmercury compounds; coasts; sodium chloride; temperature; surface water; desorption; gas chromatography-mass spectrometry
Abstract:: ... In this work, making use of experimental designs, headspace-stir bar sorptive extraction (HS-SBSE) followed by thermal desorption (TD) coupled to a gas chromatography-mass spectrometry (GC-MS) for the simultaneous determination of mercury and tin organometallic compounds present in surface water, sediment and biological tissue was optimized. All solid samples require a previous extraction typicall ...
DOI:: 10.1016/j.chroma.2008.01.046
: https://doi.org/10.1016/j.chroma.2008.01.046

54. Solid-phase analytical derivatization of alkylphenols in fish bile for gas chromatography-mass spectrometry analysis

Author:: Jonsson, Grete; Cavcic, Admira; Stokke, Tone U.; Beyer, Jonny; Sundt, Rolf C.; Brede, Cato
Source:: Journal of chromatography 2008 v.1183 no.1-2 pp. 6-14
ISSN:: 0021-9673
Subject:: derivatization; detection limit; ionization; Gadus morhua; arylsulfatase; industry; oils; bile; pollution; cod (fish); beta-glucuronidase; alkylation; gas chromatography-mass spectrometry
Abstract:: ... Solid-phase analytical derivatization (SPAD) with bis(trimethylsilyl)trifluoroacetamide (BSTFA) has successfully been used as a sample preparation method for determination of (APs) in fish bile treated with β-glucuronidase and sulfatase. Derivatized APs were analysed by gas chromatography-mass spectrometry in the electron ionization mode (GC-EI-MS). Overall limits of detection (LODs) ranged from 5 ...
DOI:: 10.1016/j.chroma.2007.12.047
: https://doi.org/10.1016/j.chroma.2007.12.047

55. Speciation of butyl and phenyltin compounds using dispersive liquid-liquid microextraction and gas chromatography-flame photometric detection

Author:: Birjandi, Afsoon Pajand; Bidari, Araz; Rezaei, Fatemeh; Hosseini, Mohammad Reza Milani; Assadi, Yaghoub
Source:: Journal of chromatography 2008 v.1193 no.1-2 pp. 19-25
ISSN:: 0021-9673
Subject:: derivatization; detection limit; gas chromatography; liquid-phase microextraction; pH; river water; seawater; sodium; solvents; tin
Abstract:: ... Dispersive liquid-liquid microextraction and gas chromatography-flame photometric detection (DLLME-GC-FPD) were performed for the speciation of butyl and phenyltin compounds in water samples after derivatization with sodium tetraethylborate (NaBEt₄). Some important parameters, such as pH, amount of NaBEt₄, derivatization time, kind and volume of extraction and disperser solvents, extraction time a ...
DOI:: 10.1016/j.chroma.2008.04.003
: https://doi.org/10.1016/j.chroma.2008.04.003

56. Speciation of butyltin compounds in environmental and biological samples using headspace single drop microextraction coupled with gas chromatography-inductively coupled plasma mass spectrometry

Author:: Xiao, Qin; Hu, Bin; He, Man
Source:: Journal of chromatography 2008 v.1211 no.1-2 pp. 135-141
ISSN:: 0021-9673
Subject:: biological speciation; chromatography; cost effectiveness; derivatization; detection limit; headspace analysis; ionic strength; mass spectrometry; microextraction; mixing; pH; seawater; sediments; shellfish; sodium; solvents; temperature
Abstract:: ... A method based on headspace single drop microextraction (HS-SDME) in combination with gas chromatography-inductively coupled plasma mass spectrometry (GC-ICP-MS) was proposed for the speciation analysis of butyltin compounds in environmental and biological samples. The sodium tetraethylborate (NaBEt₄) and sodium tetrahydroborate (NaBH₄) were used as the derivatizing reagent for in situ derivatizat ...
DOI:: 10.1016/j.chroma.2008.09.089
: https://doi.org/10.1016/j.chroma.2008.09.089

57. Steroid hormone determination in water using an environmentally friendly membrane based extraction technique

Author:: Zorita, Saioa; Hallgren, Pär; Mathiasson, Lennart
Source:: Journal of chromatography 2008 v.1192 no.1 pp. 1-8
ISSN:: 0021-9673
Subject:: correlation; derivatization; detection limit; wastewater; liquid-liquid extraction; humic acids; estrone; pH; solvents; steroid hormones; estradiol; gas chromatography-mass spectrometry; Sweden
Abstract:: ... In this study, a method was developed for determination of steroid hormones (17β-estradiol, estrone, 17α-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid i ...
DOI:: 10.1016/j.chroma.2008.03.030
: https://doi.org/10.1016/j.chroma.2008.03.030

58. Study of some UV filters stability in chlorinated water and identification of halogenated by-products by gas chromatography-mass spectrometry

Author:: Negreira, N.; Canosa, P.; Rodríguez, I.; Ramil, M.; Rubí, E.; Cela, R.
Source:: Journal of chromatography 2008 v.1178 no.1-2 pp. 206-214
ISSN:: 0021-9673
Subject:: byproducts; chlorination; chlorine; derivatization; filters; gas chromatography; half life; hydrogen; mass spectrometry; metabolites; pH; solid phase extraction; ultraviolet radiation; water
Abstract:: ... This work studies the stability of three UV filters: 2-ethylhexyl salicylate (ES), 2-ethylhexyl 4-(dimethylamino) benzoate (EHPABA) and 2-hydroxy-4-methoxybenzophenone (BP-3), in water samples containing low concentrations of free chlorine. Moreover, 2,4-dihydroxybenzophenone (2,4-DHBP), a metabolite of BP-3, was also included in some of the performed assays. Experiments were carried out consideri ...
DOI:: 10.1016/j.chroma.2007.11.057
: https://doi.org/10.1016/j.chroma.2007.11.057

59. Synthesis of chiral hydrazine reagents and their application for liquid chromatographic separation of carbonyl compounds via diastereomer formation

Author:: Bhushan, Ravi; Kumar, Virender
Source:: Journal of chromatography 2008 v.1190 no.1-2 pp. 86-94
ISSN:: 0021-9673
Subject:: absorbance; amides; amino acids; carbonyl compounds; derivatization; detection limit; diastereomers; fluorine; high performance liquid chromatography; hydrazine; ketones; solvents
Abstract:: ... Five new chiral derivatizing reagents 5-hydrazino-2,4-dinitrophenyl-l-alaninamide (HDNP-l-Ala-NH₂), 5-hydrazino-2,4-dinitrophenyl-l-phenylalaninamide (HDNP-l-Phe-NH₂), 5-hydrazino-2,4-dinitrophenyl-l-valinamide (HDNP-l-Val-NH₂), 5-hydrazino-2,4-dinitrophenyl-l-leucinamide (HDNP-l-Leu-NH₂) and 5-hydrazino-2,4-dinitrophenyl-l-phenylglycinamide (HDNP-d-Phg-NH₂) were synthesized by straightforward two ...
DOI:: 10.1016/j.chroma.2008.02.084
: https://doi.org/10.1016/j.chroma.2008.02.084

60. Ultra-performance liquid chromatographic analysis of amino acids in protein hydrolysates using an automated pre-column derivatisation method

Author:: Boogers, Ilco; Plugge, Wim; Stokkermans, Yair Q.; Duchateau, Alexander L.L.
Source:: Journal of chromatography 2008 v.1189 no.1-2 pp. 406-409
ISSN:: 0021-9673
Subject:: amino acids; blood serum; casein; cattle; derivatization; high performance liquid chromatography; hydrolysates; models; protein hydrolysates
Abstract:: ... In the present study, the changeover from the Pico·Tag HPLC method to the AccQ·Tagultra UPLC method for the analysis of amino acids in casein and bovine serum albumine hydrolysates is described. The total chromatographic run time of the AccQ·Tagultra UPLC method was only 40% of the time required for the Pico·Tag HPLC method. Quantitative results of both methods for casein and bovine serum albumine ...
DOI:: 10.1016/j.chroma.2007.11.052
: https://doi.org/10.1016/j.chroma.2007.11.052

61. Utilisation of pH stacking in conjunction with a highly absorbing chromophore, 5-aminofluorescein, to improve the sensitivity of capillary electrophoresis for carbohydrate analysis

Author:: Kazarian, Artaches A.; Hilder, Emily F.; Breadmore, Michael C.
Source:: Journal of chromatography 2008 v.1200 no.1 pp. 84-91
ISSN:: 0021-9673
Subject:: absorption; acetic acid; capillary electrophoresis; chromatography; computer simulation; derivatization; detection limit; deuterium; formic acid; glucose; lactose; maltotriose; pH
Abstract:: ... This study explores the use of pH stacking in conjunction with 5-aminofluorescein as a derivatization agent for the sensitive analysis of simple sugars such as glucose, lactose and maltotriose by capillary electrophoresis (CE). The derivatization agent was selected on the basis of its extremely high molar absorptivity, its compatibility with a 488nm light-emitting diode (LED) and the fact that it ...
DOI:: 10.1016/j.chroma.2008.04.022
: https://doi.org/10.1016/j.chroma.2008.04.022

62. A fast derivatization procedure for gas chromatographic analysis of perfluorinated organic acids

Author:: Dufková, Veronika; Čabala, Radomír; Maradová, Doubravka; Štícha, Martin
Source:: Journal of chromatography 2009 v.1216 no.49 pp. 8659-8664
ISSN:: 0021-9673
Subject:: acetonitrile; catalytic activity; derivatization; esters; gas chromatography; high performance liquid chromatography; ionization; mass spectrometry; organic acids and salts; pH; pyridines; river water
Abstract:: ... A rapid and simple derivatization procedure has been developed for gas chromatographic determination of perfluorinated organic acids (PFCAs, C₆-C₁₂), using isobutyl chloroformate (IBCF) to convert the acids into the more volatile isobutyl esters, under catalysis by pyridine. The procedure was optimized in an acetonitrile medium and applied to GC techniques with electron-capture detection (GC-ECD) ...
DOI:: 10.1016/j.chroma.2009.10.042
: https://doi.org/10.1016/j.chroma.2009.10.042

63. A novel headspace solid-phase microextraction method using in situ derivatization and a diethoxydiphenylsilane fibre for the gas chromatography-mass spectrometry determination of urinary hydroxy polycyclic aromatic hydrocarbons

Author:: Mattarozzi, M.; Musci, M.; Careri, M.; Mangia, A.; Fustinoni, S.; Campo, L.; Bianchi, F.
Source:: Journal of chromatography 2009 v.1216 no.30 pp. 5634-5639
ISSN:: 0021-9673
Subject:: derivatization; urine; humans; experimental design; polycyclic aromatic hydrocarbons; headspace analysis; regression analysis; urinalysis; enzymatic hydrolysis; solid phase microextraction; sodium chloride; temperature; metabolites; gas chromatography-mass spectrometry
Abstract:: ... An innovative and simple headspace solid-phase microextraction method using a novel diethoxydiphenylsilane fibre based on in situ derivatization with acetic anhydride was optimized and validated for the gas chromatography-mass spectrometry determination of some monohydroxy metabolites of polycyclic aromatic hydrocarbons, namely 1-hydroxynaphthalene, 2-hydroxynaphtalene, 9-hydroxyfluorene, 2-hydrox ...
DOI:: 10.1016/j.chroma.2009.05.072
: https://doi.org/10.1016/j.chroma.2009.05.072

64. A sensitive post-column photochemical derivatization/fluorimetric detection system for HPLC determination of bisphosphonates

Author:: Pérez-Ruiz, Tomás; Martínez-Lozano, Carmen; García-Martínez, María Dolores
Source:: Journal of chromatography 2009 v.1216 no.9 pp. 1312-1318
ISSN:: 0021-9673
Subject:: EDTA (chelating agent); acetonitrile; calcium chloride; calcium phosphates; derivatization; detection limit; ethylene; fluorescence; fluorometry; high performance liquid chromatography; humans; molybdates; orthophosphates; oxidation; pH; photolysis; thiamin; urine
Abstract:: ... A new reversed-phase ion-pair high-performance liquid chromatographic (HPLC) method has been developed for the determination of the following bisphosphonic acids: alendronic acid (ALEN), etidronic acid (ETID), ibandronic acid (IBAN) and risedronic acid (RISE). Separation was achieved on a C₁₈ column using a mixture of 50mmolL⁻¹ borate buffer pH 9.0 containing 0.25mmolL⁻¹ tetrabutylammonium chlorid ...
DOI:: 10.1016/j.chroma.2008.12.051
: https://doi.org/10.1016/j.chroma.2008.12.051

65. Amino acid analysis by high-performance liquid chromatography after derivatization with 9-fluorenylmethyloxycarbonyl chloride : Literature overview and further study

Author:: Jámbor, A.; Molnár-Perl, I.
Source:: Journal of chromatography 2009 v.1216 no.15 pp. 3064-3077
ISSN:: 0021-9673
Subject:: acetonitrile; acids; amino acid composition; cystine; derivatization; fluorescence; high performance liquid chromatography; histidine; pH; serine; solvents; tryptophan; tyrosine; valine
Abstract:: ... A literature overview is given of HPLC methods currently in use to determine amino acids as their 9-fluorenylmethyloxycarbonyl (FMOC) derivatives. On the basis of the detailed literature overview an exhaustive derivatization study was performed with 22 amino acids, applying photodiode array (DAD) and fluorescence (FL) detection simultaneously, in order to clear up the controversial points of FMOC ...
DOI:: 10.1016/j.chroma.2009.01.068
: https://doi.org/10.1016/j.chroma.2009.01.068

66. Aminoglycoside antibiotics may interfere with microbial amino sugar analysis

Author:: Liang, Chao; Pedersen, Joel A.; Balser, Teri C.
Source:: Journal of chromatography 2009 v.1216 no.27 pp. 5296-5301
ISSN:: 0021-9673
Subject:: acetates; amikacin; biomarkers; chromatography; derivatization; fungi; galactosamine; glucosamine; mass spectrometry; muramic acid; soil; streptomycin; tobramycin
Abstract:: ... The amino sugars (e.g., glucosamine, galactosamine, mannosamine, muramic acid) in soils are frequently employed as biomarkers of microbial residues. The analysis of amino sugars in environmental matrices, however, is expected to be more complicated than their determination in isolated microbial cells. In this study, we employed a widely used protocol for amino sugar analysis, and found that some a ...
DOI:: 10.1016/j.chroma.2009.05.010
: https://doi.org/10.1016/j.chroma.2009.05.010

67. An evaluation of microwave-assisted derivatization procedures using hyphenated mass spectrometric techniques

Author:: Damm, Markus; Rechberger, Gerald; Kollroser, Manfred; Kappe, C. Oliver
Source:: Journal of chromatography 2009 v.1216 no.31 pp. 5875-5881
ISSN:: 0021-9673
Subject:: acetylation; codeine; derivatization; dielectric heating; equipment; gas chromatography; heat transfer; liquid chromatography; mass spectrometry; microwave radiation; microwave treatment; morphine; standard operating procedures; temperature
Abstract:: ... The potential of microwave-assisted derivatization techniques in systematic toxicological analysis using gas chromatography coupled with mass spectrometry (GC-MS) was evaluated. Special emphasis was placed on the use of dedicated microwave reactors incorporating online temperature and pressure control. The use of such equipment allowed a detailed analysis of several microwave-assisted derivatizati ...
DOI:: 10.1016/j.chroma.2009.06.035
: https://doi.org/10.1016/j.chroma.2009.06.035

68. Analysis of formose sugar and formaldehyde by high-performance liquid chromatography

Author:: Iqbal, Md. Zafar; Novalin, Senad
Source:: Journal of chromatography 2009 v.1216 no.26 pp. 5116-5121
ISSN:: 0021-9673
Subject:: derivatization; formaldehyde; high performance liquid chromatography; reducing sugars; ultraviolet radiation; wavelengths
Abstract:: ... Formose sugar and formaldehyde (HCHO) were analyzed using high-performance liquid chromatography (HPLC) utilizing a CarboPac PA1 column (Dionex) and pulsed amperometric detection. This HPLC system was unsuitable for the analysis of formose sugar and HCHO and thus reducing sugars and unconverted HCHO were determined by endowing them with charges through a derivatization method using 2,4-dinitrophen ...
DOI:: 10.1016/j.chroma.2009.04.065
: https://doi.org/10.1016/j.chroma.2009.04.065

69. Analysis of hydroxylated polycyclic aromatic hydrocarbons in urine using comprehensive two-dimensional gas chromatography with a flame ionization detector

Author:: Amorim, Leiliane Coelho André; Dimandja, Jean-Marie; Cardeal, Zenilda de Lourdes
Source:: Journal of chromatography 2009 v.1216 no.14 pp. 2900-2904
ISSN:: 0021-9673
Subject:: carcinogens; comprehensive two-dimensional gas chromatography; derivatization; flame ionization; humans; ionization; liquid-liquid extraction; metabolites; microwave treatment; polycyclic aromatic hydrocarbons; urinalysis; urine; variance
Abstract:: ... The determination of polycyclic aromatic hydrocarbon (PAH) metabolites in human urine is the method of choice for assessing exposure to carcinogenic compounds. The objective of this study was the development of a comprehensive two-dimensional gas chromatography (GCxGC) method using a flame ionisation detector (FID) to simultaneously determine 10 hydroxylated PAH. The method was based on enzymatic ...
DOI:: 10.1016/j.chroma.2008.11.012
: https://doi.org/10.1016/j.chroma.2008.11.012

70. Analysis of trace levels of domoic acid in seawater and plankton by liquid chromatography without derivatization, using UV or mass spectrometry detection

Author:: Mafra, Luiz L.; Léger, Claude; Bates, Stephen S.; Quilliam, Michael A.
Source:: Journal of chromatography 2009 v.1216 no.32 pp. 6003-6011
ISSN:: 0021-9673
Subject:: derivatization; detection limit; domoic acid; fluorescence; liquid chromatography; mass spectrometry; plankton; seawater; solid phase extraction
Abstract:: ... Quantitation of trace levels of domoic acid (DA) in seawater samples usually requires labour-intensive protocols involving chemical derivatization with 9-fluorenylmethylchloroformate and liquid chromatography with fluorescence detection (FMOC-LC-FLD). Procedures based on LC-MS have been published, but time-consuming and costly solid-phase extraction pre-concentration steps are required to achieve ...
DOI:: 10.1016/j.chroma.2009.06.050
: https://doi.org/10.1016/j.chroma.2009.06.050

71. Analysis of β-agonists and β-blockers in urine using hollow fibre-protected liquid-phase microextraction with in situ derivatization followed by gas chromatography/mass spectrometry

Author:: Liu, Wei; Zhang, Lan; Wei, Zhenyi; Chen, Shengping; Chen, Guonan
Source:: Journal of chromatography 2009 v.1216 no.28 pp. 5340-5346
ISSN:: 0021-9673
Subject:: beta-adrenergic agonists; beta-adrenergic antagonists; clenbuterol; derivatization; detection limit; gas chromatography; humans; liquid-phase microextraction; mass spectrometry; mixing; monitoring; pH; propranolol; sodium chloride; solvents; sports; urine
Abstract:: ... A method using hollow fibre-protected liquid-phase microextraction (HF-LPME) with in situ derivatization followed by gas chromatography/mass spectrometry (GC/MS) was established for the analysis of β-agonists and β-blockers in urine. Because it can simultaneously extract and derivatize compounds of interest by methylbenzol and N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) in HF-LPME, the ...
DOI:: 10.1016/j.chroma.2009.05.040
: https://doi.org/10.1016/j.chroma.2009.05.040

72. Application of dynamic liquid-phase microextraction and injection port derivatization combined with gas chromatography-mass spectrometry to the determination of acidic pharmaceutically active compounds in water samples

Author:: Zhang, Jie; Lee, Hian Kee
Source:: Journal of chromatography 2009 v.1216 no.44 pp. 7527-7532
ISSN:: 0021-9673
Subject:: derivatization; detection limit; agitation; monitoring; ketoprofen; tap water; liquid-phase microextraction; ibuprofen; solvents; wastewater; clofibric acid; gas chromatography-mass spectrometry
Abstract:: ... A method has been established for the determination of four pharmaceutically active compounds (ibuprofen, ketoprofen, naproxen and clofibric acid) in water samples using dynamic hollow fiber liquid-phase microextraction (HF/LPME) followed by gas chromatography (GC) injection port derivatization and GC-mass spectrometric (MS) determination. Dynamic HF/LPME is a novel approach to microextraction tha ...
DOI:: 10.1016/j.chroma.2009.03.051
: https://doi.org/10.1016/j.chroma.2009.03.051

73. Chemical reactions in liquid-phase microextraction

Author:: Xu, Li; Basheer, Chanbasha; Lee, Hian Kee
Source:: Journal of chromatography 2009 v.1216 no.4 pp. 701-707
ISSN:: 0021-9673
Subject:: catalytic activity; chromatography; derivatization; forensic sciences; liquid-phase microextraction; solvents
Abstract:: ... In recent years, liquid-phase microextraction (LPME), a microscale implementation of liquid-liquid extraction, has become a very popular sample pretreatment technique because it combines extraction and enrichment, and is inexpensive, easy to operate and nearly solvent-free. Especially so in hollow fiber-protected LPME, sample cleanup is also effected. Essentially, owing to its high sample-to-extra ...
DOI:: 10.1016/j.chroma.2008.10.005
: https://doi.org/10.1016/j.chroma.2008.10.005

74. Combination of solid phase extraction and in vial solid phase derivatization using a strong anion exchange disk for the determination of nerve agent markers

Author:: Subramaniam, Raja; Åstot, Crister; Nilsson, Calle; Östin, Anders
Source:: Journal of chromatography 2009 v.1216 no.48 pp. 8452-8459
ISSN:: 0021-9673
Subject:: acids; anion exchange; cross contamination; derivatization; experimental design; forensic sciences; gas chromatography; mass spectrometry; multivariate analysis; nerve tissue; quantitative analysis; risk; solid phase extraction
Abstract:: ... Alkylphosphonic acids (APAs) are degradation products and chemical markers of organophosphorous (OP) nerve agents (chemical warfare agents). Anion exchange disk-based solid phase extraction (SPE) has been combined with in vial solid phase derivatization (SPD) and GC-MS analysis for the determination of APAs in aqueous samples. The optimization of critical method parameters, such as the SPD reactio ...
DOI:: 10.1016/j.chroma.2009.10.017
: https://doi.org/10.1016/j.chroma.2009.10.017

75. Combination of ¹H nuclear magnetic resonance spectroscopy and mass spectrometry as tools for investigation of the thermolytic and solvolytic effects : Case of carbamates analysis

Author:: Przybylski, Cédric; Bonnet, Véronique
Source:: Journal of chromatography 2009 v.1216 no.23 pp. 4787-4797
ISSN:: 0021-9673
Subject:: acetic acid; acetonitrile; carbaryl; carbofuran; chlorpropham; derivatization; extensibility; gas chromatography; mass spectrometry; nuclear magnetic resonance spectroscopy; solvents; temperature; toluene
Abstract:: ... The carbamate pesticides are a well known thermo-sensible compound class. Under unfavourable conditions, these compounds are highly prone to degradation via fragmentation and/or rearrangement mechanisms. Their transformation processes are observed in consequence of two factors: structure with fragile bonds on the one hand and a stressing environment on the other hand leading to a difficult direct ...
DOI:: 10.1016/j.chroma.2009.04.016
: https://doi.org/10.1016/j.chroma.2009.04.016

76. Comparative application of microwave, ultrasonication, ultracentrifugation and conventional heating for preparation of sample as dinitrophenyl derivative for direct enantioseparation of certain amino alcohols and 1-amino-2-propanol from vitamin B₁₂ hydrolysate on α₁-acid glycoprotein and β-cyclodextrin columns

Author:: Bhushan, Ravi; Kumar, Rajender
Source:: Journal of chromatography 2009 v.1216 no.45 pp. 7941-7945
ISSN:: 0021-9673
Subject:: amino acids; amino alcohols; beta-cyclodextrin; chromatography; derivatization; detection limit; glycoproteins; heat; hydrolysates; microwave radiation; ultracentrifugation; ultrasonic treatment; vitamin B12
Abstract:: ... Taking into account the structural similarities of amino alcohols with amino acids and in order to reduce time for derivatization unconventional approaches viz. microwave irradiation, ultrasonication and ultra centrifugation were applied for synthesis of dinitrophenyl derivatives of nine amino alcohols and to work out a method of choice for sample preparation for direct enantioseparation. The enan ...
DOI:: 10.1016/j.chroma.2009.09.049
: https://doi.org/10.1016/j.chroma.2009.09.049

77. Comparison of several sorbents for continuous in situ derivatization and preconcentration of low-molecular mass aldehydes prior to liquid chromatography-tandem mass spectrometric determination in water samples

Author:: Baños, Clara Eugenia; Silva, Manuel
Source:: Journal of chromatography 2009 v.1216 no.38 pp. 6554-6559
ISSN:: 0021-9673
Subject:: fullerene; silica; derivatization; detection limit; carbon nanotubes; cost analysis; adsorbents; mass spectrometry; liquid chromatography; aldehydes
Abstract:: ... A comparative study of six SPE conventional and non-conventional sorbent materials (silica RP-C₁₈, LiChrolut EN, Amberlite XAD-2, C₆₀ fullerene, multiwall carbon nanotubes and graphitized carbon black) was carried out for the in situ derivatization/preconcentration of eight aldehydes with 2,4-dinitrophenylhydrazine. Although two of the sorbents, LiChrolut EN and RP-C₁₈, turned out to be the most s ...
DOI:: 10.1016/j.chroma.2009.08.004
: https://doi.org/10.1016/j.chroma.2009.08.004

78. Constant pressure-assisted head-column field-amplified sample injection in combination with in-capillary derivatization for enhancing the sensitivity of capillary electrophoresis

Author:: Yan, Na; Zhou, Lei; Zhu, Zaifang; Zhang, Huige; Zhou, Ximin; Chen, Xingguo
Source:: Journal of chromatography 2009 v.1216 no.20 pp. 4517-4523
ISSN:: 0021-9673
Subject:: capillary electrophoresis; chromatography; derivatization; detection limit; electrolytes; glufosinate; mixing; temperature
Abstract:: ... In this work, a novel method combining constant pressure-assisted head-column field-amplified sample injection (PA-HC-FASI) with in-capillary derivatization was developed for enhancing the sensitivity of capillary electrophoresis. PA-HC-FASI uses an appropriate positive pressure to counterbalance the electroosmotic flow in the capillary column during electrokinetic injection, while taking advantag ...
DOI:: 10.1016/j.chroma.2009.03.042
: https://doi.org/10.1016/j.chroma.2009.03.042

79. Densitometric determination of (+)-catechin and (-)-epicatechin by 4-dimethylaminocinnamaldehyde reagent

Author:: Glavnik, Vesna; Simonovska, Breda; Vovk, Irena
Source:: Journal of chromatography 2009 v.1216 no.20 pp. 4485-4491
ISSN:: 0021-9673
Subject:: cellulose; color; densitometry; derivatization; detection limit; flavanols; hydrochloric acid; thin layer chromatography; vanillin
Abstract:: ... We report the optimization of a sensitive, selective and robust derivatization method using 4-dimethylaminocinnamaldehyde (DMACA) for densitometric determination of (+)-catechin and (-)-epicatechin. The separation of these compounds was achieved by thin-layer chromatography (TLC) on cellulose plates developed with water. With DMACA in HCl, both compounds gave blue bands, while under the same condi ...
DOI:: 10.1016/j.chroma.2009.03.026
: https://doi.org/10.1016/j.chroma.2009.03.026

80. Determination of arylamines and aminopyridines in pharmaceutical products using in-situ derivatization and liquid chromatography-mass spectrometry

Author:: Vanhoenacker, Gerd; Dumont, Emmie; David, Frank; Baker, Andrew; Sandra, Pat
Source:: Journal of chromatography 2009 v.1216 no.16 pp. 3563-3570
ISSN:: 0021-9673
Subject:: derivatization; drugs; genotoxicity; ingredients; liquid chromatography; mass spectrometry; molecular weight; monitoring; solutes
Abstract:: ... Arylamines and aminopyridines form a class of potentially genotoxic impurities (PGIs) that can be present at trace levels in active pharmaceutical ingredients (APIs). A generic method was developed that allows the analysis of a selected set of these solutes at sub-ppm level relative to the drug substance. A highly concentrated solution of the pharmaceutical compound is analyzed by LC-MS using a si ...
DOI:: 10.1016/j.chroma.2008.08.102
: https://doi.org/10.1016/j.chroma.2008.08.102

81. Determination of carbonyl compounds in beer by derivatisation and headspace solid-phase microextraction in combination with gas chromatography and mass spectrometry

Author:: Saison, Daan; De Schutter, David P.; Delvaux, Filip; Delvaux, Freddy R.
Source:: Journal of chromatography 2009 v.1216 no.26 pp. 5061-5068
ISSN:: 0021-9673
Subject:: beers; carbonyl compounds; food analysis; chemical reactions; headspace analysis; microextraction; solid phase extraction; gas chromatography; mass spectrometry
Abstract:: ... Headspace solid-phase microextraction (SPME) followed by gas chromatography and mass spectrometry was applied for quantification of 41 chemically diverse carbonyl compounds in beer. Therefore, in-solution derivatisation with o-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine (PFBHA) combined with SPME was optimised for fibre selection, PFBHA concentration, extraction temperature and time and ionic stren ...
DOI:: 10.1016/j.chroma.2009.04.077
PubMed:: 19450805
: https://doi.org/10.1016/j.chroma.2009.04.077

82. Determination of endocrine-disrupting chemicals in the liquid and solid phases of activated sludge by solid phase extraction and gas chromatography-mass spectrometry

Author:: Nie, Yafeng; Qiang, Zhimin; Zhang, Heqing; Adams, Craig
Source:: Journal of chromatography 2009 v.1216 no.42 pp. 7071-7080
ISSN:: 0021-9673
Subject:: activated sludge; endocrine-disrupting chemicals; derivatization; bisphenol A; sewage treatment; sewage sludge; estrone; estriol; estradiol; solid phase extraction; gas chromatography-mass spectrometry; China
Abstract:: ... The highly complex matrix of activated sludge in sewage treatment plants (STPs) makes it difficult to detect endocrine-disrupting chemicals (EDCs) which are usually present at low concentration levels. To date, no literature has reported the concentrations of steroid estrogens in activated sludge in China and very limited data are available worldwide. In this work, a highly selective and sensitive ...
DOI:: 10.1016/j.chroma.2009.08.064
: https://doi.org/10.1016/j.chroma.2009.08.064

83. Determination of fatty alcohol ethoxylates with diphenic anhydride derivatization and liquid chromatography with spectrophotometric detection : A comparative study with other anhydrides

Author:: Micó-Tormos, A.; Bianchi, F.; Simó-Alfonso, E.F.; Ramis-Ramos, G.
Source:: Journal of chromatography 2009 v.1216 no.15 pp. 3023-3030
ISSN:: 0021-9673
Subject:: acetic acid; acetonitrile; alcohols; anhydrides; derivatization; detection limit; ethylene oxide; maleates; phthalates; reversed-phase high performance liquid chromatography; seawater; urea; wastewater treatment; wavelengths
Abstract:: ... A method for the determination of fatty alcohol ethoxylates (FAEs) using diphenic anhydride as derivatization reagent and RP-HPLC separation with UV-vis detection is presented and compared to derivatization with maleic, phthalic, and other cyclic anhydrides. With these anhydrides, the reaction rates increased when urea was added to the reaction medium, and the yields did not decrease when the samp ...
DOI:: 10.1016/j.chroma.2009.01.100
: https://doi.org/10.1016/j.chroma.2009.01.100

84. Determination of fecal sterols by gas chromatography-mass spectrometry with solid-phase extraction and injection-port derivatization

Author:: Wu, Jingming; Hu, Ruikang; Yue, Junqi; Yang, Zhaoguang; Zhang, Lifeng
Source:: Journal of chromatography 2009 v.1216 no.7 pp. 1053-1058
ISSN:: 0021-9673
Subject:: coprostanol; derivatization; detection limit; cholesterol; solvents; temperature; solid phase extraction; gas chromatography-mass spectrometry
Abstract:: ... Injection-port derivatization combined with solid-phase extraction (SPE) was developed and applied for the first time to determine five types of fecal sterols (coprostanol, cholestanol, epicholestanol, epicoprostanol and cholesterol) with gas chromatography-mass spectrometry (GC-MS). In this method, silylation of fecal sterols was performed with N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) at ...
DOI:: 10.1016/j.chroma.2008.12.054
: https://doi.org/10.1016/j.chroma.2008.12.054

85. Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in human hair by gas chromatography-negative chemical ionization mass spectrometry

Author:: Schummer, Claude; Appenzeller, Brice M.R.; Millet, Maurice; Wennig, Robert
Source:: Journal of chromatography 2009 v.1216 no.32 pp. 6012-6019
ISSN:: 0021-9673
Subject:: derivatization; detection limit; sodium hydroxide; decontamination; humans; phenanthrenes; ionization; methylene chloride; chromatography; enzymatic treatment; urinalysis; washing; hydrolysis; volunteers; mass spectrometry; beta-glucuronidase; metabolites; chronic exposure
Abstract:: ... The study describes the determination of mono-hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs), metabolites of PAHs, in human hair. Twelve selected OH-PAHs from two to four rings, generally determined in urine analysis, were investigated as markers of human exposure to PAHs. Following hydrolysis of hair specimens of 50-300mg with 1M NaOH, OH-PAHs were extracted using dichloromethane and sub ...
DOI:: 10.1016/j.chroma.2009.05.068
: https://doi.org/10.1016/j.chroma.2009.05.068

86. Determination of linear aliphatic aldehydes in heavy metal containing waters by high-performance liquid chromatography using 2,4-dinitrophenylhydrazine derivatization

Author:: Lin, Yi-Liang; Wang, Po-Yen; Hsieh, Ling-Ling; Ku, Kuan-Hsuan; Yeh, Yun-Tai; Wu, Chien-Hou
Source:: Journal of chromatography 2009 v.1216 no.36 pp. 6377-6381
ISSN:: 0021-9673
Subject:: EDTA (chelating agent); adsorption; copper; derivatization; detection limit; formaldehyde; heavy metals; high performance liquid chromatography; metal ions; oxidants; pH
Abstract:: ... A simple and sensitive method is described for the determination of picomolar amounts of C₁-C₉ linear aliphatic aldehydes in waters containing heavy metal ions. In this method, aldehydes were first derivatized with 2,4-dinitrophenylhydrazine (DNPH) at optimized pH 1.8 for 30min and analyzed by HPLC with UV detector at 365nm. Factors affecting the derivatization reaction of aldehydes and DNPH were ...
DOI:: 10.1016/j.chroma.2009.07.018
: https://doi.org/10.1016/j.chroma.2009.07.018

87. Determination of phenylalanine in blood by high-performance anion-exchange chromatography-pulsed amperometric detection to diagnose phenylketonuria

Author:: Jeong, Ji-Seon; Sim, Hee-Jung; Lee, Yong-Moon; Yoon, Hye-Ran; Lee, Dong Hwan; Hong, Seon-Pyo
Source:: Journal of chromatography 2009 v.1216 no.30 pp. 5709-5714
ISSN:: 0021-9673
Subject:: anion exchange; anion exchange chromatography; blood; derivatization; detection limit; monitoring; phenylalanine; phenylketonuria; rapid methods; screening
Abstract:: ... We have developed a high-performance anion-exchange chromatography with pulsed amperometric detection method for the detection of phenylalanine (Phe) and diagnosis of phenylketonuria (PKU). Sample pretreatment steps were simplified without derivatization. The analyte was separated within 5min. The detection limit (S/N=3) for Phe was 50pg. Linear dynamic range was 1.23-14.43mg/dL (r ² =0.9999) for ...
DOI:: 10.1016/j.chroma.2009.06.004
: https://doi.org/10.1016/j.chroma.2009.06.004

88. Dispersive liquid-liquid microextraction applied to the simultaneous derivatization and concentration of triclosan and methyltriclosan in water samples

Author:: Montes, R.; Rodríguez, I.; Rubí, E.; Cela, R.
Source:: Journal of chromatography 2009 v.1216 no.2 pp. 205-210
ISSN:: 0021-9673
Subject:: aquatic environment; centrifugation; derivatization; gas chromatography; glass; liquid-phase microextraction; methanol; tandem mass spectrometry; wastewater; working conditions
Abstract:: ... A fast and novel sample preparation procedure for the determination of triclosan (TCS) and methyltriclosan (MTCS) in water samples is presented. Dispersive liquid-liquid microextraction, using a ternary mixture consisting of a disperser, an extractant and N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide (MTBSTFA) as derivatization reagent, was used for the simultaneous derivatization, case o ...
DOI:: 10.1016/j.chroma.2008.11.068
: https://doi.org/10.1016/j.chroma.2008.11.068

89. Enhanced detectability of fluorinated derivatives of N,N-dialkylamino alcohols and precursors of nitrogen mustards by gas chromatography coupled to Fourier transform infrared spectroscopy analysis for verification of chemical weapons convention

Author:: Garg, Prabhat; Purohit, Ajay; Tak, Vijay K.; Dubey, D.K.
Source:: Journal of chromatography 2009 v.1216 no.45 pp. 7906-7914
ISSN:: 0021-9673
Subject:: Fourier transform infrared spectroscopy; absorbance; alcohols; chemical analysis; derivatization; detection limit; gas chromatography; mass spectrometry; nerve tissue; nitrogen
Abstract:: ... N,N-Dialkylamino alcohols, N-methyldiethanolamine, N-ethyldiethanolamine and triethanolamine are the precursors of VX type nerve agents and three different nitrogen mustards respectively. Their detection and identification is of paramount importance for verification analysis of chemical weapons convention. GC-FTIR is used as complimentary technique to GC-MS analysis for identification of these ana ...
DOI:: 10.1016/j.chroma.2009.09.032
: https://doi.org/10.1016/j.chroma.2009.09.032

90. Fast, sensitive and highly discriminant gas chromatography-mass spectrometry method for profiling analysis of fatty acids in serum

Author:: Sánchez-Ávila, N.; Mata-Granados, J.M.; Ruiz-Jiménez, J.; Luque de Castro, M.D.
Source:: Journal of chromatography 2009 v.1216 no.40 pp. 6864-6872
ISSN:: 0021-9673
Subject:: epidemiological studies; derivatization; essential fatty acids; blood serum; humans; cis-trans isomers; free fatty acids; ultrasonics; esterification; gas chromatography-mass spectrometry
Abstract:: ... A method for the determination of fatty acids in serum based on GC-MS (micro-SIS detection mode) has been developed and the separation and cis/trans isomers have been identified. A prior two-step extraction/derivatization procedure accelerated by ultrasound allows individual determination of esterified (EFAs) and non-esterified fatty acids (NEFAs), and shortening of the derivatization steps to 5mi ...
DOI:: 10.1016/j.chroma.2009.08.045
: https://doi.org/10.1016/j.chroma.2009.08.045

91. Fluorogenic derivatization of aryl halides based on the formation of biphenyl by Suzuki coupling reaction with phenylboronic acid

Author:: Kishikawa, Naoya; Kubo, Kimiko; Hammad, Sherin Farouk; Mabrouk, Mokhtar Mohamed; Habib, Ahmed; Elfatatry, Hamed; Ohyama, Kaname; Nakashima, Kenichiro; Kuroda, Naotaka
Source:: Journal of chromatography 2009 v.1216 no.40 pp. 6873-6876
ISSN:: 0021-9673
Subject:: acetates; biphenyl; bromides; catalysts; chromatography; derivatization; detection limit; fluorescence; palladium; wavelengths
Abstract:: ... The fluorogenic derivatization method for aryl halide was developed for the first time. This method was based on the formation of fluorescent biphenyl structure by Suzuki coupling reaction between aryl halides and non-fluorescent phenylboronic acid (PBA). We measured the fluorescence spectra of the products obtained by the reaction of p-substituted aryl bromides (i.e., 4-bromobenzonitrile, 4-bromo ...
DOI:: 10.1016/j.chroma.2009.08.040
: https://doi.org/10.1016/j.chroma.2009.08.040

92. Gas chromatography-mass spectrometry analysis of pheomelanin degradation products

Author:: Nezirević Dernroth, Dženeta; Rundström, Annica; Kågedal, Bertil
Source:: Journal of chromatography 2009 v.1216 no.30 pp. 5730-5739
ISSN:: 0021-9673
Subject:: risk; derivatization; urine; melanoma; melanin; Whites; esters; patients; acid hydrolysis; chloroform; gas chromatography-mass spectrometry
Abstract:: ... Melanoma is most rapidly increasing in the white population and people with pheomelanin skin type are at high risk to develop melanoma. However, little is known about the pheomelanin structure and function, and further elucidation of this melanin is therefore an important task. A GC/MS method was developed based on hydriodic acid hydrolysis of pheomelanin in the urine. Derivatization was performed ...
DOI:: 10.1016/j.chroma.2009.05.063
: https://doi.org/10.1016/j.chroma.2009.05.063

93. Gas chromatography-mass spectrometry resolution of sugar acid enantiomers on a permethylated β-cyclodextrin stationary phase

Author:: Cooper, George; Sant, Minakshi; Asiyo, Cynthia
Source:: Journal of chromatography 2009 v.1216 no.40 pp. 6838-6843
ISSN:: 0021-9673
Subject:: derivatization; enantiomers; ions; monosaccharides; beta-cyclodextrin; aldonic acids; gas chromatography-mass spectrometry
Abstract:: ... Analysis of compounds in meteorites revealed a need to simultaneously characterize multiple enantiomers of sugar acids (aldonic acids) present in trace amounts. Analyses by gas chromatography-mass spectrometry demonstrated that all but two of the three-carbon through six-carbon straight-chained sugar acid enantiomer pairs could be resolved using a single derivatization procedure and one set of GC ...
DOI:: 10.1016/j.chroma.2009.07.073
: https://doi.org/10.1016/j.chroma.2009.07.073

94. Gas chromatography-mass spectrometry screening methods for select UV filters, synthetic musks, alkylphenols, an antimicrobial agent, and an insect repellent in fish

Author:: Mottaleb, Mohammad A.; Usenko, Sascha; O'Donnell, John G.; Ramirez, Alejandro J.; Brooks, Bryan W.; Chambliss, C. Kevin
Source:: Journal of chromatography 2009 v.1216 no.5 pp. 815-823
ISSN:: 0021-9673
Subject:: derivatization; personal care products; anthropogenic activities; fish; acetone; benzophenones; detection limit; insect repellents; screening; tissues; gas chromatography-mass spectrometry; monitoring; surfactants; filters; lipid content; anti-infective agents; physicochemical properties; streams; tandem mass spectrometry; solvents; fish fillets; Texas
Abstract:: ... Two screening methods have been developed for simultaneous determination of ten extensively used personal care products (PCPs) and two alkylphenol surfactants in fish. The methods consisted of extraction, clean-up, derivatization and analysis by gas chromatography-mass spectrometry with selected ion monitoring (GC-SIM-MS) or gas chromatography-tandem mass spectrometry (GC-MS/MS) techniques. Among ...
DOI:: 10.1016/j.chroma.2008.11.072
: https://doi.org/10.1016/j.chroma.2008.11.072

95. Improved determination of milk oligosaccharides using a single derivatization with anthranilic acid and separation by reversed-phase high-performance liquid chromatography

Author:: Leo, Fiame; Asakuma, Sadaki; Nakamura, Tadashi; Fukuda, Kenji; Senda, Akitsugu; Urashima, Tadasu
Source:: Journal of chromatography 2009 v.1216 no.9 pp. 1520-1523
ISSN:: 0021-9673
Subject:: ammonium acetate; anthranilic acid; breast milk; citrates; derivatization; detection limit; fluorescence; gel chromatography; isomers; milk; oligosaccharides; pH; reversed-phase high performance liquid chromatography; wavelengths; Samoa
Abstract:: ... An improved analytical scheme for human milk neutral oligosaccharides determination was developed, in which, the oligosaccharides were pooled in two fractions (pools 1 and 2) after gel filtration, and then were quantitatively derivatized with a single fluorescent reagent, 2-anthranilic acid. Separation was by reversed-phase HPLC on an ODS-100Z column with a mobile phase of 50mM ammonium acetate pH ...
DOI:: 10.1016/j.chroma.2009.01.015
: https://doi.org/10.1016/j.chroma.2009.01.015

96. In situ derivatization reaction and determination of ibuprofen in water samples using headspace generation-programmed temperature vaporization-gas chromatography-mass spectrometry

Author:: Pérez Pavón, José Luis; Casas Ferreira, Ana María; Fernández Laespada, María Esther; Moreno Cordero, Bernardo
Source:: Journal of chromatography 2009 v.1216 no.39 pp. 6728-6734
ISSN:: 0021-9673
Subject:: derivatization; detection limit; mixing; headspace analysis; ibuprofen; solvents; temperature; wastewater; gas chromatography-mass spectrometry
Abstract:: ... The aim of the present work is to propose a method for the determination of ibuprofen, as a typical representative of pharmaceutical compounds, in aqueous samples. To do so, an in situ derivatization reaction in aqueous medium was employed in the vial of a headspace sampler (HS), after which instrumental measurements were made with gas chromatography-mass spectrometry (GC-MS). As the injection sys ...
DOI:: 10.1016/j.chroma.2009.08.011
: https://doi.org/10.1016/j.chroma.2009.08.011

97. Liquid chromatographic determination of polythiols based on pre-column excimer fluorescence derivatization and its application to α-lipoic acid analysis

Author:: Inoue, Takashi; Sudo, Maki; Yoshida, Hideyuki; Todoroki, Kenichiro; Nohta, Hitoshi; Yamaguchi, Masatoshi
Source:: Journal of chromatography 2009 v.1216 no.44 pp. 7564-7569
ISSN:: 0021-9673
Subject:: chromatography; derivatization; detection limit; dietary supplements; dithiothreitol; fluorescence; fluorometry; humans; lipoic acid; urine
Abstract:: ... We developed an LC method for the sensitive and selective fluorometric determination of polythiols. This method employs pre-column intramolecular excimer-forming fluorescence derivatization with N-(1-pyrene)iodoacetamide followed by LC separation. Polythiols were converted to the corresponding dipyrene-labeled derivatives, and the derivatives afforded intramolecular excimer fluorescence (440-540nm ...
DOI:: 10.1016/j.chroma.2009.02.035
: https://doi.org/10.1016/j.chroma.2009.02.035

98. Mass transfer kinetic mechanism in monolithic columns and application to the characterization of new research monolithic samples with different average pore sizes

Author:: Gritti, Fabrice; Guiochon, Georges
Source:: Journal of chromatography 2009 v.1216 no.23 pp. 4752-4767
ISSN:: 0021-9673
Subject:: adsorption; chromatography; derivatization; diffusivity; energy; equations; insulin; mass transfer; molecular weight; phenol; toluene
Abstract:: ... A general reduced HETP (height equivalent to a theoretical plate) equation is proposed that accounts for the mass transfer of a wide range of molecular weight compounds in monolithic columns. The detailed derivatization of each one of the individual and independent mass transfer contributions (longitudinal diffusion, eddy dispersion, film mass transfer resistance, and trans-skeleton mass transfer ...
DOI:: 10.1016/j.chroma.2009.04.034
: https://doi.org/10.1016/j.chroma.2009.04.034

99. Multiresidue analysis of pollutants as their trimethylsilyl derivatives, by gas chromatography-mass spectrometry

Author:: Sebők, Á.; Vasanits-Zsigrai, A.; Helenkár, A.; Záray, Gy.; Molnár-Perl, I.
Source:: Journal of chromatography 2009 v.1216 no.12 pp. 2288-2301
ISSN:: 0021-9673
Subject:: derivatization; ions; 2,5-dihydroxybenzoic acid; pollutants; cholesterol; phthalates; pH; dicarboxylic acids; multiresidue analysis; acetaminophen; saturated fatty acids; benzoic acid; wastewater; solid phase extraction; gas chromatography-mass spectrometry; Danube River
Abstract:: ... This paper reports a multiresidue analysis procedure which permits the identification and quantification of sixty-three water-soluble pollutants. Subsequent to their solid-phase extraction (SPE) enrichment, analyses of species have been carried out from one solution, by a single injection, as their trimethylsilyl-oxime ether/ester derivatives, by gas chromatography-mass spectrometry, within 31min. ...
DOI:: 10.1016/j.chroma.2009.01.056
: https://doi.org/10.1016/j.chroma.2009.01.056

100. New gas chromatographic method for the enantioseparation of β-amino acids by a rapid double derivatization technique

Author:: Forró, Enikő
Source:: Journal of chromatography 2009 v.1216 no.6 pp. 1025-1029
ISSN:: 0021-9673
Subject:: acids; chromatography; derivatization; esterification
Abstract:: ... A novel gas chromatographic method was developed for the enantioseparation of valuable acyclic and carbocyclic cis- and trans-β-amino acids, including cispentacin and a number of its analogues and homologues. Excellent (in most cases baseline) separation was achieved for the racemates of these β-amino acids on CP-Chirasil-Dex CB or CP-Chirasil L-Val columns after a simple and rapid double derivati ...
DOI:: 10.1016/j.chroma.2008.12.040
: https://doi.org/10.1016/j.chroma.2008.12.040

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1. Simplified method for determination of polycarbamate fungicide in water samples by liquid chromatography with tandem mass spectrometry following derivatization with dimethyl sulfate

2. A denuder-impinger system with in situ derivatization followed by gas chromatography-mass spectrometry for the determination of gaseous iodine-containing halogen species

3. A novel derivatization approach for simultaneous determination of glyoxal, methylglyoxal, and 3-deoxyglucosone in plasma by gas chromatography-mass spectrometry

4. Active single-drop microextraction for the determination of gaseous diisocyanates

5. Analysis of formaldehyde formation in wastewater using on-fiber derivatization-solid-phase microextraction-gas chromatography-mass spectrometry

6. Application of acetate derivatives for gas chromatography-mass spectrometry: Novel approaches on carbohydrates, lipids and amino acids analysis

7. Automated on-line in-tube solid-phase microextraction-assisted derivatization coupled to liquid chromatography for quantifying residual dimethylamine in cationic polymers

8. Capillary electrochromatographic separation of racemates on a norvancomycin-bonded monolithic column under reversed-phase conditions

9. Capillary electrophoresis of aminoglycosides with argon-ion laser-induced fluorescence detection

10. Comparison of four extraction/methylation analytical methods to measure fatty acid composition by gas chromatography in meat

11. Design and synthesis of a novel fluorescent reagent, 6-oxy-(ethylpiperazine)-9-(2'-methoxycarbonyl) fluorescein, for carboxylic acids and its application in food samples using high-performance liquid chromatography

12. Determination of C₈₀ tetra-acid content in calcium naphthenate deposits

13. Determination of basic degradation products of chemical warfare agents in water using hollow fibre-protected liquid-phase microextraction with in-situ derivatisation followed by gas chromatography-mass spectrometry

14. Determination of fatty alcohol ethoxylates by derivatisation with maleic anhydride followed by liquid chromatography with UV-vis detection

15. Determination of fatty alcohol ethoxylates by derivatization with phthalic anhydride followed by liquid chromatography with UV-vis detection

16. Determination of galactose and mannose residues in natural galactomannans using a fast and efficient high-performance liquid chromatography/UV detection

17. Determination of phenols and chlorophenols as trimethylsilyl derivatives using gas chromatography-mass spectrometry

18. Determination of the carbon isotopic composition of whole/intact biological specimens using at-line direct thermal desorption to effect thermally assisted hydrolysis/methylation

19. Determination of γ-hydroxybutyric acid in clinical samples using capillary electrophoresis with contactless conductivity detection

20. Development of C₁₈-functionalized magnetic silica nanoparticles as sample preparation technique for the determination of ergosterol in cigarettes by microwave-assisted derivatization and gas chromatography/mass spectrometry

21. Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids

22. Direct quantification of steroid glucuronides in human urine by liquid chromatography-electrospray tandem mass spectrometry

23. Dynamic ultrasound-assisted extraction coupled on-line with solid support derivatization and high-performance liquid chromatography for the determination of formaldehyde in textiles

24. Enantioselective gas chromatographic analysis of aqueous samples by on-line derivatisation

25. Enhancing sensitivity of liquid chromatographic/ion-trap tandem mass spectrometric determination of estrogens by on-line pre-column derivatization

26. Evaluation of solid-phase microextraction methods for determination of trace concentration aldehydes in aqueous solution

27. Evaluation of various derivatization approaches for gas chromatography-mass spectrometry analysis of buprenorphine and norbuprenorphine

28. Extending the molecular application range of gas chromatography

29. Field analysis of acetaldehyde in mainstream tobacco smoke using solid-phase microextraction and a portable gas chromatograph

30. Fluoroalkyl chloroformates in treating amino acids for gas chromatographic analysis

31. Gas chromatography-mass spectrometry of the trimethylsilyl (oxime) ether/ester derivatives of cholic acids: Their presence in the aquatic environment

32. Gradient elution isotachophoresis with direct ultraviolet absorption detection for sensitive amino acid analysis

33. Highly sensitive detection of pharmaceutical compounds in biological fluids using capillary electrophoresis coupled with laser-induced native fluorescence

34. Hydroxyproline quantification for the estimation of collagen in tissue using multiple reaction monitoring mass spectrometry

35. In-capillary derivatization and analysis of ephedrine and pseudoephedrine by micellar electrokinetic chromatography with laser-induced fluorescence detection

36. In-capillary derivatization and capillary electrophoresis separation of amino acid neurotransmitters from brain microdialysis samples

37. Indirect enantioseparation of α-amino acids by reversed-phase liquid chromatography using new chiral derivatizing reagents synthesized from s-triazine chloride

38. Ion-pair single-drop microextraction versus phase-transfer catalytic extraction for the gas chromatographic determination of phenols as tosylated derivatives

39. Liquid chromatographic resolution of vigabatrin and its analogue γ-amino acids on chiral stationary phases based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid

40. Mercury speciation and analysis in drinking water by stir bar sorptive extraction with in situ propyl derivatization and thermal desorption-gas chromatography-mass spectrometry

41. Multivariate optimization approach for the analysis of butyltin compounds in mussel tissues by gas chromatography-mass spectrometry

42. Multivariate optimization of a derivatisation procedure for the simultaneous determination of nine anabolic steroids by gas chromatography coupled with mass spectrometry

43. On-column electrochemical redox derivatization for enhancement of separation selectivity of liquid chromatography

44. Purge-assisted headspace solid-phase microextraction combined with gas chromatography-mass spectrometry for determination of chlorophenols in aqueous samples

45. Quantification of N-acetyl- and N-glycolylneuraminic acids by a stable isotope dilution assay using high-performance liquid chromatography-tandem mass spectrometry

46. Rapid screening of methamphetamines in human serum by headspace solid-phase microextraction using a dodecylsulfate-doped polypyrrole film coupled to ion mobility spectrometry

47. Relative efficiency of free fatty acid butyl esterification

48. Separation of amino acid enantiomers VIA chiral derivatization and non-chiral gas chromatography

49. Simultaneous analysis of benzophenone sunscreen compounds in water sample by stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography-mass spectrometry

50. Simultaneous derivatization and extraction of amphetamine and methylenedioxyamphetamine in urine with headspace liquid-phase microextraction followed by gas chromatography-mass spectrometry

51. Simultaneous determination of derivatized light aldehydes by microchip electrophoresis with electrochemical detection

52. Simultaneous liquid-liquid microextraction/methylation for the determination of haloacetic acids in drinking waters by headspace gas chromatography

53. Simultaneous speciation of methylmercury and butyltin species in environmental samples by headspace-stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry

54. Solid-phase analytical derivatization of alkylphenols in fish bile for gas chromatography-mass spectrometry analysis

55. Speciation of butyl and phenyltin compounds using dispersive liquid-liquid microextraction and gas chromatography-flame photometric detection

56. Speciation of butyltin compounds in environmental and biological samples using headspace single drop microextraction coupled with gas chromatography-inductively coupled plasma mass spectrometry

57. Steroid hormone determination in water using an environmentally friendly membrane based extraction technique

58. Study of some UV filters stability in chlorinated water and identification of halogenated by-products by gas chromatography-mass spectrometry

59. Synthesis of chiral hydrazine reagents and their application for liquid chromatographic separation of carbonyl compounds via diastereomer formation

60. Ultra-performance liquid chromatographic analysis of amino acids in protein hydrolysates using an automated pre-column derivatisation method

61. Utilisation of pH stacking in conjunction with a highly absorbing chromophore, 5-aminofluorescein, to improve the sensitivity of capillary electrophoresis for carbohydrate analysis

62. A fast derivatization procedure for gas chromatographic analysis of perfluorinated organic acids

63. A novel headspace solid-phase microextraction method using in situ derivatization and a diethoxydiphenylsilane fibre for the gas chromatography-mass spectrometry determination of urinary hydroxy polycyclic aromatic hydrocarbons

64. A sensitive post-column photochemical derivatization/fluorimetric detection system for HPLC determination of bisphosphonates

65. Amino acid analysis by high-performance liquid chromatography after derivatization with 9-fluorenylmethyloxycarbonyl chloride : Literature overview and further study

66. Aminoglycoside antibiotics may interfere with microbial amino sugar analysis

67. An evaluation of microwave-assisted derivatization procedures using hyphenated mass spectrometric techniques

68. Analysis of formose sugar and formaldehyde by high-performance liquid chromatography

69. Analysis of hydroxylated polycyclic aromatic hydrocarbons in urine using comprehensive two-dimensional gas chromatography with a flame ionization detector

70. Analysis of trace levels of domoic acid in seawater and plankton by liquid chromatography without derivatization, using UV or mass spectrometry detection