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You searched for: Journal name Journal of chromatography Remove constraint Journal name: Journal of chromatography Subject term ethyl ether Remove constraint Subject term: ethyl ether
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1. A method to assess glyphosate, glufosinate and aminomethylphosphonic acid in soil and earthworms

Author:
Olivier Delhomme; Anaïs Rodrigues; Ana Hernandez; Supansa Chimjarn; Colette Bertrand; Marjolaine Bourdat-Deschamps; Clémentine Fritsch; Céline Pelosi; Sylvie Nélieu; Maurice Millet
Source:
Journal of chromatography 2021 v.1651 pp. 462339
ISSN:
0021-9673
Subject:
Allolobophora chlorotica; borates; ethyl ether; formic acid; glufosinate; glyphosate; liquid chromatography; liquid-liquid extraction; methanol; purification methods; soil; solid phase extraction; tandem mass spectrometry
Abstract:
... A new sensitive and selective analytical methodology to quantify glyphosate (GLY), aminomethylphosphonic acid (AMPA), and glufosinate (GLU) in both soil and earthworms (Allolobophora chlorotica) was developed. The extraction and purification methods were optimized. The samples were extracted with various aqueous solutions (HNO₃, H₂O, KOH and borate buffer) and derivatized with 9-Fluorenylmethyl ch ...
DOI:
10.1016/j.chroma.2021.462339

2. A modified approach for isolation of essential oil from fruit of Amorpha fruticosa Linn using microwave-assisted hydrodistillation concatenated liquid-liquid extraction

Author:
Fengli Chen; Jia Jia; Qiang Zhang; Huiyan Gu; Lei Yang
Source:
Journal of chromatography 2017 v.1524 pp. 254-265
ISSN:
0021-9673
Subject:
Amorpha fruticosa; distillates; essential oils; ethyl ether; gas chromatography-mass spectrometry; herbs; hydrodistillation; liquid-liquid extraction; microwave radiation; microwave treatment; solvents; volatile compounds
Abstract:
... In this work, a modified technique was developed to separate essential oil from the fruit of Amorpha fruticosa using microwave-assisted hydrodistillation concatenated liquid-liquid extraction (MHD-LLE). The new apparatus consists of two series-wound separation columns for separating essential oil, one is the conventional oil-water separation column, and the other is the extraction column of compon ...
DOI:
10.1016/j.chroma.2017.10.008

3. A sensitive LC–MS/MS method for determination of levamisole in human plasma: Application to pharmacokinetic study

Author:
Liping Tong; Likun Ding; Yan Li; Zhirui Wang; Jingwen Wang; Yu Liu; Lin Yang; Aidong Wen
Source:
Journal of chromatography 2011 v.879 no.5-6 pp. 299-303
ISSN:
1570-0232
Subject:
acetonitrile; ammonium acetate; blood plasma; ethyl ether; humans; ionization; levamisole; liquid chromatography; mebendazole; pharmacokinetics; tandem mass spectrometry
Abstract:
... A sensitive and rapid LC–MS/MS method was developed and validated for the determination of levamisole in human plasma. The assay was based on liquid–liquid extraction of analytes from human plasma with ethyl ether. Chromatographic separation was carried on an Agilent HC-C₈ column (150mm×4.6mm, 5μm) at 40°C, with a mobile phase consisting of acetonitrile—10mM ammonium acetate (70:30, v/v), a flow r ...
DOI:
10.1016/j.jchromb.2010.11.015
PubMed:
21256094

4. A simple, cheap and reliable method for control of 4-ethylphenol and 4-ethylguaiacol in red wines. Screening of fining agents for reducing volatile phenols levels in red wines

Author:
Juliana Milheiro; Luís Filipe-Ribeiro; Fernanda Cosme; Fernando M. Nunes
Source:
Journal of chromatography 2017 v.1041-1042 pp. 183-190
ISSN:
1570-0232
Subject:
Dekkera; activated carbon; carboxymethylcellulose; chitosan; control methods; coumaric acids; egg albumen; ethyl ether; gas chromatography-mass spectrometry; headspace analysis; liquid-liquid extraction; odors; pentane; phenols; physicochemical properties; quality control; red wines; reducing agents; screening; uncertainty
Abstract:
... Brettanomyces/Dekkera produces 4-ethylphenol (4-EP) and 4-ethylguaiacol (4-EG) from hydroxycinnamic acids that affect the wine aroma and overall quality. A simple, cheap, fast and reliable quantitation method is needed for routine quality control of wines. In this work a simple method based on one simple liquid–liquid extraction with pentane/diethyl ether (2:1) and analysis by GC–MS allow to obtai ...
DOI:
10.1016/j.jchromb.2016.10.036

5. A simple, rapid and stability indicating validated method for quantification of lamotrigine in human plasma and dry plasma spot using LC-ESI–MS/MS: Application in clinical study

Author:
Kuldeep Kumar Namdev; Jaya Dwivedi; Deepak Chandra Chilkoti; Swapnil Sharma
Source:
Journal of chromatography 2018 v.1072 pp. 362-369
ISSN:
1570-0232
Subject:
acetone; humans; monitoring; ionization; spectrometers; liquid-liquid extraction; therapeutics; liquid chromatography; statistical analysis; blood; ethyl ether; epilepsy
Abstract:
... Lamotrigine (LTZ) is a phenyltriazine derivative which belongs to anti-epileptic drugs (AEDs) class and prescribed as mono- or adjunctive-therapy in treatment of epilepsy. Therapeutic drug monitoring (TDM) of AEDs provides a valid clinical tool in optimization of overall therapy. However, TDM is challenging due to the high biological samples (plasma/blood) storage/shipment costs and the limited av ...
DOI:
10.1016/j.jchromb.2017.11.040

6. A validated LC-MS/MS assay for the quantification of phosphodiesterase-5 inhibitors in human plasma

Author:
Camilla Regina de Souza Madeira; Mariana Millan Fachi; Victor Concentino; Alexandre de Fátima Cobre; Angela Cristina Leal Badaró Trindade; Alan Guilherme Gonçalves; Roberto Pontarolo
Source:
Journal of chromatography 2021 v.1179 pp. 122829
ISSN:
1570-0232
Subject:
acetonitrile; ammonium; ethyl ether; formates; formic acid; humans; markets; pharmacokinetics; sulfaquinoxaline; therapeutics
Abstract:
... Phosphodiesterase inhibitors (PDE5i) are considered the first line therapy for erectile dysfunction. All PDE5i available on the market are structurally related; their main differences relate to their pharmacokinetic parameters. For these treatments to be effective and safe, it is necessary that these drugs are in the appropriate doses and that they reach adequate concentrations in the plasma. For ...
DOI:
10.1016/j.jchromb.2021.122829

7. A validated UPLC–MS/MS method for the analysis of linezolid and a novel oxazolidinone derivative (PH027) in plasma and its application to tissue distribution study in rabbits

Author:
Mohsen A. Hedaya; Vidhya Thomas; Mohamed E. Abdel-Hamid; Elijah O. Kehinde; Oludotun A. Phillips
Source:
Journal of chromatography 2017 v.1040 pp. 89-96
ISSN:
1570-0232
Subject:
acetonitrile; ammonium acetate; antibacterial properties; antibiotics; chromatography; ethyl ether; evaporation; intravenous injection; linezolid; monitoring; pharmacokinetics; quality control; quantitative analysis; rabbits; tissue distribution; tissues
Abstract:
... Linezolid is the first approved oxazolidinone antibacterial agent, whereas PH027 is a novel compound of the same class that exhibits good in vitro antibacterial activity. The objective of this study was to develop an UPLC–MS/MS assay for the analysis of linezolid and PH027 in plasma and to apply the method for comparative pharmacokinetic and tissue distribution studies of both compounds.Plasma sam ...
DOI:
10.1016/j.jchromb.2016.11.034

8. An improved LC–MS/MS method for the simultaneous determination of pyrazinamide, pyrazinoic acid and 5-hydroxy pyrazinoic acid in human plasma for a pharmacokinetic study

Author:
Priyanka A. Shah; Primal Sharma; Jaivik V. Shah; Mallika Sanyal; Pranav S. Shrivastav
Source:
Journal of chromatography 2016 v.1017-1018 pp. 52-61
ISSN:
1570-0232
Subject:
acetic acid; bioavailability; chromatography; ethyl ether; humans; ionization; liquid-liquid extraction; metabolites; methanol; monitoring; pharmacokinetics; spectrometers; storage conditions
Abstract:
... In the present work the plasma levels of PZA and its two active metabolites, pyrazinoic acid (PA) and 5-hydroxy pyrazinoic acid (5-OH PA) were determined by a sensitive and rapid LC–MS/MS method. The analytes and their labeled internal standards were extracted from 200μL plasma samples by liquid-liquid extraction with methyl tert-butyl ether: diethyl ether (90:10, v/v) under acidic conditions. The ...
DOI:
10.1016/j.jchromb.2016.02.036

9. Chlorpromazine quantification in human plasma by UPLC–electrospray ionization tandem mass spectrometry. Application to a comparative pharmacokinetic study

Author:
Ney Carter Borges; Vinicius Marcondes Rezende; Jose Marcos Santana; Ricardo Pereira Moreira; Roberto Fernandes Moreira; Patrícia Moreno; Diego Carter Borges; José Luiz Donato; Ronilson Agnaldo Moreno
Source:
Journal of chromatography 2011 v.879 no.31 pp. 3728-3734
ISSN:
1570-0232
Subject:
absorption; acetonitrile; bioavailability; chlorpromazine; cross-over studies; ethyl ether; formic acid; humans; ionization; liquid-liquid extraction; methylene chloride; pharmacokinetics; spectrometers; tandem mass spectrometry; ultra-performance liquid chromatography
Abstract:
... In the present study a method to quantify chlorpromazine in human plasma using cyclobenzaprine as the internal standard (IS) is described. The analyte and the IS were extracted from human plasma by a liquid–liquid extraction with diethyl ether/dichloromethane (70/30, v/v) and analyzed by an ultra performance liquid chromatography (UPLC) coupled to an electrospray tandem triple quadrupole mass spec ...
DOI:
10.1016/j.jchromb.2011.10.020

10. Ciprofibrate quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry for pharmacokinetic studies

Author:
Fabiana D. Mendes; Lu Shi Chen; André Borges; Tainah Babadópulos; Jaime O. Ilha; Khalid M. Alkharfy; Gustavo D. Mendes; Gilberto De Nucci
Source:
Journal of chromatography 2011 v.879 no.24 pp. 2361-2368
ISSN:
1570-0232
Subject:
Food and Drug Administration; absorption; acetic acid; acetonitrile; confidence interval; energy; ethyl ether; formic acid; high performance liquid chromatography; humans; liquid-liquid extraction; methylene chloride; pharmacokinetics; solvents; tandem mass spectrometry; volunteers; United States
Abstract:
... A rapid, sensitive and specific method for quantifying ciprofibrate in human plasma using bezafibrate as the internal standard (IS) is described. The sample was acidified prior extraction with formic acid (88%). The analyte and the IS were extracted from plasma by liquid–liquid extraction using an organic solvent (diethyl ether/dichloromethane 70/30 (v/v)). The extracts were analyzed by high perfo ...
DOI:
10.1016/j.jchromb.2011.05.055

11. Detection of dexmedetomidine in human breast milk using liquid chromatography–tandem mass spectrometry: Application to a study of drug safety in breastfeeding after Cesarean section

Author:
Rika Nakanishi; Manabu Yoshimura; Manabu Suno; Kento Yamamoto; Haruka Ito; Yohei Uchimine; Takashi Toriumi; Atsushi Kurosawa; Ami Sugawara; Takayuki Kunisawa
Source:
Journal of chromatography 2017 v.1040 pp. 208-213
ISSN:
1570-0232
Subject:
acetonitrile; breast feeding; breast milk; cesarean section; dexmedetomidine; ethyl ether; formic acid; high performance liquid chromatography; humans; ionization; liquid-liquid extraction; patients; spectrometers; tandem mass spectrometry
Abstract:
... Several analytical methods for dexmedetomidine (DEX) in human plasma have been published, but quantification of DEX in human breast milk has not been described. In this article, we describe a high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) method suitable for quantification of DEX in human breast milk. DEX and an internal standard were extracted in a single liquid–liqu ...
DOI:
10.1016/j.jchromb.2016.11.015

12. Determination of 3-methyl-2,4-nonanedione in red wines using methanol chemical ionization ion trap mass spectrometry

Author:
Alexandre Pons; Valérie Lavigne; Philippe Darriet; Denis Dubourdieu
Source:
Journal of chromatography 2011 v.1218 no.39 pp. 7023-7030
ISSN:
0021-9673
Subject:
acetone; acetonitrile; chromatography; derivatization; detection limit; ethyl acetate; ethyl ether; flavor; heptane; ionization; mass spectrometry; methanol; pentane; red wines
Abstract:
... A compound associated with oxidized flavor in red wines was recently-identified as 3-methyl-2,4-nonanedione (MND). In order to quantify it, positive chemical ionization (PCI) in an ion trap was studied using conventional liquid reagents such as methanol, acetonitrile, and acetone, as well as non-conventional liquid reagents such as ethyl acetate, diethyl ether, pentane, isohexane, and heptane. Und ...
DOI:
10.1016/j.chroma.2011.08.017

13. Determination of brusatol in plasma and tissues by LC–MS method and its application to a pharmacokinetic and distribution study in mice

Author:
Nan Guo; Xiaoran Zhang; Fanlong Bu; Lei Wang; Zhanqi Cao; Chunmei Geng; Ruichen Guo; Dongmei Ren; Qing Wen
Source:
Journal of chromatography 2017 v.1053 pp. 20-26
ISSN:
1570-0232
Subject:
Brucea javanica; antineoplastic activity; caudal vein; ethyl ether; liquid chromatography; mass spectrometry; methanol; mice; monitoring; nitrogen; pharmacokinetics; quality control; statistical analysis
Abstract:
... The quassinoid brusatol, which can be isolated from Brucea javanica (L.) Merr., becomes popularly studied because of its anti-tumor activity. In order to further investigate brusatol and extend its applications, a sensitive analytical method for determination of brusatol in biological samples is essential. However, few methods had been reported until now. In this study, a highly sensitive and repr ...
DOI:
10.1016/j.jchromb.2017.04.012

14. Determination of irinotecan and its metabolite SN-38 in rabbit plasma and tumors using a validated method of tandem mass spectrometry coupled with liquid chromatography

Author:
Dae J. Park; Jun H. Won; A.R. Cho; Hye J. Yun; Jeong H. Heo; Tae H. Hwhang; Dae H. Lee; Woo M. Kim
Source:
Journal of chromatography 2014 v.962 pp. 147-152
ISSN:
1570-0232
Subject:
alkalinization; ethyl acetate; ethyl ether; formates; formic acid; ionization; liquid chromatography; metabolites; neoplasms; pH; pharmacokinetics; rabbits; tandem mass spectrometry
Abstract:
... New tandem mass spectrometric method coupled with liquid chromatography (LC–MS/MS) has been developed to determine the total concentration of camptothecin derivatives (irinotecan and SN-38) regardless of inter-conversion phenomenon between carboxylate and lactone forms. At first, all sample solutions were acidified for 1h in order to completely convert CPT derivatives into their lactone forms and ...
DOI:
10.1016/j.jchromb.2014.05.042

15. Determination of quinalphos in human whole blood samples by high-performance thin-layer chromatography for forensic applications

Author:
Praveen U Sanganalmath; Purigali M Nagaraju; Kuruba Sreeramulu
Source:
Journal of chromatography 2019 v.1594 pp. 181-189
ISSN:
0021-9673
Subject:
absorbance; blood; blood sampling; densitometry; ethyl ether; forensic sciences; humans; liquid-liquid extraction; pH; poisoning; quinalphos; regression analysis; silica gel; solvents; storage conditions; thin layer chromatography
Abstract:
... A simple and rapid procedure for the determination of quinalphos in human whole blood using liquid-liquid extraction and high-performance thin-layer chromatography was developed and validated. Seven different organic solvents were tested for optimum extraction of quinalphos from spiked blood samples. The effect of pH on the extraction yield of quinalphos was also examined. An average recovery of 9 ...
DOI:
10.1016/j.chroma.2019.02.003

16. Determination of sterols using liquid chromatography with off-line surface-assisted laser desorption/ionization mass spectrometry

Author:
Blanka Vrbková; Vendula Roblová; Edward S. Yeung; Jan Preisler
Source:
Journal of chromatography 2014 v.1358 pp. 102-109
ISSN:
0021-9673
Subject:
beta-sitosterol; campesterol; cationization; cholesterol; desorption; detection limit; ethyl ether; gas chromatography-mass spectrometry; linseed oil; nanosilver; non-polar compounds; olive oil; reversed-phase liquid chromatography; saponification; silver; stigmasterol; sunflower oil
Abstract:
... A new method, reversed phase liquid chromatography with off-line surface-assisted laser desorption/ionization mass spectrometry (RPLC–SALDI MS) for the determination of brassicasterol (BR), cholesterol (CH), stigmasterol (ST), campesterol (CA) and β-sitosterol (SI) in oil samples has been developed. The sample preparation consisted of alkaline saponification followed by extraction of the unsaponif ...
DOI:
10.1016/j.chroma.2014.06.077

17. Development and validation of LC–MS/MS assays for the quantification of E7080 and metabolites in various human biological matrices

Author:
A.C. Dubbelman; H. Rosing; B. Thijssen; A. Gebretensae; L. Lucas; H. Chen; R. Shumaker; J.H.M. Schellens; J.H. Beijnen
Source:
Journal of chromatography 2012 v.887-888 no. pp. 25-34
ISSN:
1570-0232
Subject:
acetonitrile; antineoplastic agents; blood; ethyl ether; feces; formic acid; humans; liquid chromatography; metabolites; pharmacokinetics; spectrometers; tandem mass spectrometry; urine
Abstract:
... To support clinical pharmacokinetic studies with the anticancer agent E7080 (lenvatinib), liquid chromatography tandem mass spectrometry (LC–MS/MS) methods were developed for the quantification of E7080 and four of its metabolites in human plasma, urine and faeces and of E7080 in whole blood. Cross-analyte interferences between metabolites and parent compound were expected and therefore accounted ...
DOI:
10.1016/j.jchromb.2012.01.004

18. Development and validation of a GC-FID method for the analysis of short chain fatty acids in rat and human faeces and in fermentation fluids

Author:
Serena Scortichini; Maria Chiara Boarelli; Stefania Silvi; Dennis Fiorini
Source:
Journal of chromatography 2020 v.1143 pp. 121972
ISSN:
1570-0232
Subject:
acetic acid; acidification; chemical species; derivatization; ethyl ether; feces; fermentation; flame ionization; hexanoic acid; humans; intestinal microorganisms; metabolites; mice; polyethylene glycol; propionic acid; quantitative analysis; rats
Abstract:
... Short-chain fatty acids (SCFAs) are gut microbiota metabolites recognized for their beneficial effects on the host organism. In this study, a simple and rapid sample preparation method combined to SCFAs analysis by direct injection and gas chromatography coupled with flame ionization detection (GC-FID), for the determination and quantification of eight SCFAs (acetic, propionic, i-butyric, butyric, ...
DOI:
10.1016/j.jchromb.2020.121972

19. Development and validation of a liquid chromatography–tandem mass spectrometry method for the quantitative determination of gamithromycin in animal plasma, lung tissue and pulmonary epithelial lining fluid

Author:
Siegrid De Baere; Mathias Devreese; Anneleen Watteyn; Heidi Wyns; Elke Plessers; Patrick De Backer; Siska Croubels
Source:
Journal of chromatography 2015 v.1398 pp. 73-82
ISSN:
0021-9673
Subject:
acetonitrile; ammonium acetate; blood plasma; calibration; calves; chickens; detection limit; electrospray ionization mass spectrometry; epithelium; ethyl ether; gamithromycin; graphs; ionization; liquid chromatography; liquid-liquid extraction; lungs; monitoring; pH; pharmacokinetics; phospholipids; poults; quantitative analysis; statistical analysis; swine; tandem mass spectrometry; turkeys
Abstract:
... A sensitive and specific method for the quantitative determination of gamithromycin in animal plasma, lung tissue and pulmonary epithelial lining fluid (PELF) using liquid chromatography combined with heated electrospray ionization tandem mass spectrometry (LC–MS/MS) was developed. The sample preparation was rapid, straightforward and consisted of a deproteinization and phospholipid removal step u ...
DOI:
10.1016/j.chroma.2015.04.022

20. Development of a high-throughput screening analysis for 288 drugs and poisons in human blood using Orbitrap technology with gas chromatography-high resolution accurate mass spectrometry

Author:
Meiru Pan; Ping Xiang; Zhiguo Yu; Yunli Zhao; Hui Yan
Source:
Journal of chromatography 2019 v.1587 pp. 209-226
ISSN:
0021-9673
Subject:
acaricides; amphetamines; antidepressants; blood; blood sampling; cannabinoids; cardiovascular agents; centrifugation; chromatography; cocaine; detection limit; energy; ethyl ether; forensic sciences; fungicides; illicit drugs; insecticides; ionization; ions; mass spectrometry; molecular weight; nematicides; nonsteroidal anti-inflammatory agents; poisoning; screening; toxicity testing
Abstract:
... The screening analysis for drugs and poisons always symbolizes the capabilities of a forensic laboratory. Due to the rapid emergence of new compounds in clinical and forensic intoxication cases, sensitive and specific methods are necessary for the screening of wide range of target compounds. A novel high-throughput screening method has been developed for the toxicological analysis of 288 drugs and ...
DOI:
10.1016/j.chroma.2018.12.022

21. Development of a novel methodology for determination of dialkyl phosphates in human urine using liquid chromatography-tandem mass spectrometry

Author:
Sandra F. Fernández; Agustín Pastor; Vicent Yusà; Lidia Montesinos; Olga Pardo
Source:
Journal of chromatography 2019 pp. -
ISSN:
1570-0232
Subject:
electrospray ionization mass spectrometry; ethyl acetate; ethyl ether; experimental design; humans; lactating women; lactation; liquid chromatography; liquid-liquid extraction; magnesium sulfate; pesticide residues; phosphates; quantitative analysis; tandem mass spectrometry; urinalysis; urine
Abstract:
... In this study a fast and sensitive method was developed for the quantitative determination of six dialkyl phosphates (DAPs) in human urine using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The proposed methodology was based on liquid-liquid extraction (LLE) with diethyl ether and ethyl acetate using MgSO4 and NaCl, followed by liquid chromatography and mass spectrometry detection in ...
DOI:
10.1016/j.jchromb.2019.121810

22. Electrospun nanofibers as a new solid phase microextraction coating for determination of volatile organic impurities in biological products

Author:
Sara Zali; Ali Es-haghi; Mojtaba Shamsipur; Fahimeh Jalali
Source:
Journal of chromatography 2020 v.1153 pp. 122279
ISSN:
1570-0232
Subject:
agitation; chloroform; coatings; desorption; detection limit; energy-dispersive X-ray analysis; ethyl ether; foot-and-mouth disease; gas chromatography-mass spectrometry; ionic strength; nanofibers; polydimethylsiloxane; polystyrenes; scanning electron microscopy; solid phase microextraction; solvents; stainless steel; temperature; thermal stability; toluene; vaccines; viscosity; volatile organic compounds
Abstract:
... In this study, preparation of a solid-phase microextraction fiber of polydimethylsiloxane (PDMS) polymer in its blends with polystyrene (PS) via electrospinning process, on a stainless steel wire has been reported. The electrospining enhancement of PDMS solutions in the presence of PS is found due to the increase in the viscosity of the mixed solutions. Characteristics of the fibers were inspected ...
DOI:
10.1016/j.jchromb.2020.122279

23. Evaluation of triproline and tri-α-methylproline chiral stationary phases : Retention and enantioseparation associated with hydrogen bonding

Author:
Lao, Wenjian; Gan, Jay
Source:
Journal of chromatography 2009 v.1216 no.25 pp. 5020-5029
ISSN:
0021-9673
Subject:
acetonitrile; chromatography; enantiomers; ethyl acetate; ethyl ether; heptane; hexane; hydrogen; hydrogen bonding; proline; solvents
Abstract:
... In this study, to demonstrate preparation strategy and improve understanding of chiral recognition mechanisms, triproline chiral stationary phases (CSPs) were evaluated with a series of analytes classified as having none, one, two or three H-bond donors. The average retention factors and mobile phase strength generally followed none
DOI:
10.1016/j.chroma.2009.04.063

24. Gas chromatographic–mass spectrometric investigation of volatile and extractable compounds of crude royal jelly

Author:
V.A. Isidorov; S. Bakier; I. Grzech
Source:
Journal of chromatography 2012 v.885-886 no. pp. 109-116
ISSN:
1570-0232
Subject:
2-heptanone; ambient temperature; butyric acid; ethyl ether; free amino acids; fructose; gas chromatography-mass spectrometry; glucose; headspace analysis; methanol; octanoic acid; phenol; royal jelly; solid phase microextraction; sucrose; volatile compounds
Abstract:
... Using headspace solid-phase microextraction (HS-SPME) followed by diethyl ether and methanol extraction, it was possible to isolate as many as 185 organic compounds out of 17 samples of crude royal jelly (RJ). Of the above compound number, 169 compounds were positively identified by means of gas chromatography–mass spectrometry. The volatile fraction of RJ consists of 25 different compounds where ...
DOI:
10.1016/j.jchromb.2011.12.025

25. High-performance thin-layer chromatographic methods for the determination of febuxostat and febuxostat/diclofenac combination in human plasma

Author:
Fawzi A. El-Yazbi; Omayma A. Amin; Eman I. El-Kimary; Essam F. Khamis; Sameh E. Younis
Source:
Journal of chromatography 2018 v.1086 pp. 89-96
ISSN:
1570-0232
Subject:
bioavailability; densitometry; diclofenac; drug formulations; ethyl ether; humans; liquid-liquid extraction; males; metabolites; oral administration; petroleum; pharmacokinetics; thin layer chromatography
Abstract:
... Two simple, sensitive and specific high-performance thin-layer chromatographic (HPTLC) methods were developed for the determination of febuxostat (FEB) individually, and simultaneously with diclofenac (DIC) in human plasma. Method A presents the first HPTLC-ultraviolet attempt for FEB determination in human plasma. FEB was separated from endogenous plasma components (at hRF = 70) with ethyl acetat ...
DOI:
10.1016/j.jchromb.2018.04.020

26. Isolation and estimation of the ‘aromatic’ naphthenic acid content of an oil sands process-affected water extract

Author:
David Jones; Charles E. West; Alan G. Scarlett; Richard A. Frank; Steven J. Rowland
Source:
Journal of chromatography 2012 v.1247 no. pp. 171-175
ISSN:
0021-9673
Subject:
lipid content; oil sands; solid phase extraction; toxic substances; esters; naphthenates; hexane; ethyl ether; gas chromatography-mass spectrometry
Abstract:
... The naphthenic acids of oil sands process-affected water (OSPW) are said to be important toxicants. The major acids are stated to have alicyclic structures and recently, numerous of these have been identified, but some evidence suggests ‘aromatic’ acids are also present. The proportions of such acids have not been reported because they exist in so-called supercomplex mixtures with the alicyclic sp ...
DOI:
10.1016/j.chroma.2012.05.073

27. LC-MS/MS method for the simultaneous quantification of luteolin, wedelolactone and apigenin in mice plasma using hansen solubility parameters for liquid-liquid extraction: Application to pharmacokinetics of Eclipta alba chloroform fraction

Author:
Hanumanth Srikanth Cheruvu; Navneet K. Yadav; Guru R. Valicherla; Rakesh K. Arya; Zakir Hussain; Chetan Sharma; Kamal R. Arya; Rama K. Singh; Dipak Datta; Jiaur R. Gayen
Source:
Journal of chromatography 2018 v.1081-1082 pp. 76-86
ISSN:
1570-0232
Subject:
Ayurvedic medicine; Eclipta prostrata; acetonitrile; ammonium; apigenin; chloroform; correlation; ethyl ether; formates; formic acid; liquid chromatography; liquid-liquid extraction; luteolin; methanol; mice; oral administration; pharmacokinetics; phytopharmaceuticals; quercetin; solubility; solvents; tandem mass spectrometry
Abstract:
... Eclipta alba (Bhringraj) in ayurveda has been widely used as a traditional medicine for its multi-therapeutic properties for ages. Luteolin (LTL), wedelolactone (WDL) and apigenin (APG) are the three main bioactive phytochemicals present in Eclipta alba extract. However there was a lack of sensitive bioanalytical method for the pharmacokinetics of these free compounds in plasma which majorly contr ...
DOI:
10.1016/j.jchromb.2018.01.035

28. Monoliths from poly(ethylene glycol) diacrylate and dimethacrylate for capillary hydrophobic interaction chromatography of proteins

Author:
Li, Yuanyuan; Dennis Tolley, H.; Lee, Milton L.
Source:
Journal of chromatography 2010 v.1217 no.30 pp. 4934-4945
ISSN:
0021-9673
Subject:
biocompatibility; crosslinking; ethyl ether; ethylene glycol; hydrophobic interaction chromatography; methanol; permeability; polymerization; proteins; solvents; temperature
Abstract:
... Rigid monoliths were synthesized solely from poly(ethylene glycol) diacrylates (PEGDA) or poly(ethylene glycol) dimethacrylates (PEGDMA) containing different ethylene glycol chain lengths by one-step UV-initiated polymerization. Methanol/ethyl ether and cyclohexanol/decanol were used as bi-porogen mixtures for the PEGDA and PEGDMA monoliths, respectively. Effects of PEG chain length, bi-porogen ra ...
DOI:
10.1016/j.chroma.2010.05.048

29. Novel use of PDMS tubing for in-soil capture of plant natural products

Author:
J. Vuts; D.M. Magalhães; A.L. Soares; A.A.W. Ratnayaka; J.C. Caulfield; M.A. Birkett
Source:
Journal of chromatography 2020 v.1161 pp. 122451
ISSN:
1570-0232
Subject:
Diabrotica; chemical ecology; chemical species; corn; electrophysiology; ethyl ether; lipophilicity; methanol; polydimethylsiloxane; rhizosphere; sand; semiochemicals; silicon; soil; solvents; vapors; water content
Abstract:
... The extraction of small lipophilic molecules (SLMs) in the soil-root interface that play a role in belowground ecological interactions between plants and insect herbivores was investigated. Polydimethylsiloxane (PDMS) microtubing has been shown to absorb root SLMs selectively in low-disturbance setups, where analytes were extracted from the polymer with methanol. This technique was adapted to isol ...
DOI:
10.1016/j.jchromb.2020.122451

30. On-line derivatization with on-line coupled normal phase liquid chromatography–gas chromatography using the through oven transfer adsorption desorption interface: Application to the analysis of total sterols in edible oils

Author:
Rosa M. Toledano; Jose M. Cortés; Juan C. Andini; Ana Vázquez; Jesús Villén
Source:
Journal of chromatography 2012 v.1256 no. pp. 191-196
ISSN:
0021-9673
Subject:
adsorbents; adsorption; cooking fats and oils; derivatization; desorption; detection limit; ethyl ether; potassium hydroxide; sterols; thin layer chromatography
Abstract:
... In the present work on-line derivatization is combined with on-line normal phase liquid chromatography–gas chromatography (NPLC–GC) to analyze total sterols in edible oils. The method uses the TOTAD interface with an additional LC injection valve to automatically introduce the derivatization reagent. The derivatization reaction takes place in the adsorbent material located inside the liner of the ...
DOI:
10.1016/j.chroma.2012.07.057

31. Optimization and validation of direct gas chromatography-mass spectrometry method for simultaneous quantification of ten short-chain fatty acids in rat feces

Author:
Jin-Hao Zhu; Qian Mao; Si-Yu Wang; Hui Liu; Shan-Shan Zhou; Wei Zhang; Ming Kong; He Zhu; Song-Lin Li
Source:
Journal of chromatography 2022 v.1669 pp. 462958
ISSN:
0021-9673
Subject:
acidification; derivatization; ethyl ether; feces; formic acid; gas chromatography-mass spectrometry; rats; temperature; toxicity
Abstract:
... Short-chain fatty acids (SCFAs) play key roles in maintaining health and treating disease. Quantification of important fecal SCFAs is necessary to facilitate the clarification of their biological roles. However, the existing quantifying methods mainly depend on complicated precolumn derivatization, and/or are unable to determine formic acid, a SCFA commonly associated with toxicity. In this study, ...
DOI:
10.1016/j.chroma.2022.462958

32. Problem in the molecular area of polar probe molecules used in inverse gas chromatography

Author:
Baoli Shi
Source:
Journal of chromatography 2019 v.1601 pp. 385-387
ISSN:
0021-9673
Subject:
acetone; benzene; ethanol; ethyl acetate; ethyl ether; gas chromatography; methylene chloride; solvents; tetrahydrofuran; van der Waals forces
Abstract:
... Although the inverse gas chromatography technique has been used to measure the surface acid-base properties for almost 50 years, several basic problems still hinder its further development and application. One of the problems is that for the polar probe molecules of dichloromethane, acetone, ethyl acetate, tetrahydrofuran, and ethanol, the molecular area of each probe has different values in liter ...
DOI:
10.1016/j.chroma.2019.05.027

33. Production of all trans-beta-carotene by using impinging flow of supercritical carbon dioxide anti-solvent pulverization

Author:
Yi-Chen Shen; Lee-Muei Chng; Yuan-Chuen Wang; Chwen-Jen Shieh; Kuo-Li Lin; Shih-Lan Hsu; Hong-Nong Chou; Chieh-Ming J. Chang
Source:
Journal of chromatography 2012 v.1270 no. pp. 1-8
ISSN:
0021-9673
Subject:
Dunaliella salina; beta-carotene; carbon dioxide; chromatography; ethanol; ethyl ether; microalgae; particle size; particulates; temperature; tetrahydrofuran
Abstract:
... This work investigated column elution chromatography coupled with supercritical anti-solvent precipitation to produce carotenoid rich microsized particulates from microalgal Dunaliella salina species. The extract contained carotenoids ranging from 61.3mg/gₛₐₗᵢₙₐ to 72.5mg/gₛₐₗᵢₙₐ using ultrasonic stirred ethyl ether or tetrahydrofuran (THF) extraction. When 10L of ethyl alcohol was employed to elu ...
DOI:
10.1016/j.chroma.2012.10.036

34. Simultaneous microemulsion liquid chromatographic analysis of fat-soluble vitamins in pharmaceutical formulations: Optimization using genetic algorithm

Author:
Momenbeik, Fariborz; Roosta, Mostafa; Nikoukar, Ali Akbar
Source:
Journal of chromatography 2010 v.1217 no.24 pp. 3770-3773
ISSN:
0021-9673
Subject:
algorithms; computer software; detection limit; drug formulations; ethyl ether; fat soluble vitamins; fish oils; liquid chromatography; pH; sodium dodecyl sulfate; solvents; surfactants; syrups; temperature
Abstract:
... An environmentally benign and simple method has been proposed for separation and determination of fat-soluble vitamins using isocratic microemulsion liquid chromatography. Optimization of parameters affecting the separation selectivity and efficiency including surfactant concentration, percent of cosurfactant (1-butanol), and percent of organic oily solvent (diethyl ether), temperature and pH were ...
DOI:
10.1016/j.chroma.2010.04.012

35. Solvent-assisted stir bar sorptive extraction by using swollen polydimethylsiloxane for enhanced recovery of polar solutes in aqueous samples: Application to aroma compounds in beer and pesticides in wine

Author:
Nobuo Ochiai; Kikuo Sasamoto; Frank David; Pat Sandra
Source:
Journal of chromatography 2016 v.1455 pp. 45-56
ISSN:
0021-9673
Subject:
beers; cyclohexanes; desorption; ethyl ether; gas chromatography; mass spectrometry; methylene chloride; mixing; odor compounds; pesticides; solutes; solvents; toluene; wines
Abstract:
... A novel solvent-assisted stir bar sorptive extraction (SA-SBSE) technique was developed for enhanced recovery of polar solutes in aqueous samples. A conventional PDMS stir bar was swollen in several solvents with log Kow ranging from 1.0 to 3.5 while stirring for 30min prior to extraction. After extraction, thermal desorption – gas chromatography – (tandem) mass spectrometry (TD-GC-(MS/)MS) or liq ...
DOI:
10.1016/j.chroma.2016.05.085

36. Study of the temperature effect on the surface area of model organic molecules, the dispersive surface energy and the surface properties of solids by inverse gas chromatography

Author:
Tayssir Hamieh
Source:
Journal of chromatography 2020 v.1627 pp. 461372
ISSN:
0021-9673
Subject:
alkanes; carbon; chloroform; contact angle; energy; equations; ethyl ether; gas chromatography; methylene chloride; polytetrafluoroethylene; surface area; temperature; thermal expansion; toluene
Abstract:
... This paper demonstrated the non-validity of Schultz et al. method by proving that the surface areas of n-alkanes and polar molecules strongly depend of the temperature. Consequently, the results of surface properties obtained by this method are inaccurate. Inverse gas chromatography (IGC) at infinite dilution and the dynamic contact angle (DCA) technique were used on the polytetrafluoroethylene (P ...
DOI:
10.1016/j.chroma.2020.461372

37. Thin-layer chromatography with eutectic mobile phases—preliminary results

Author:
Danuta Raj
Source:
Journal of chromatography 2020 v.1621 pp. 461044
ISSN:
0021-9673
Subject:
Chelidonium; acetone; berberine; chloroform; ethyl ether; menthol; methanol; phenol; sanguinarine; silica gel; solvents; thin layer chromatography; ultraviolet radiation
Abstract:
... The presented paper is the first to show thin layer chromatography (TLC) analysis based on eutectic mobile phases (Deep Eutectic Solvents – DES). During the experiment 25 eutectic mixtures were investigated for their chromatographic properties. Most of them belong to the natural deep eutectic solvents (NADES) group. Also, new eutectic liquids based on phenolics and terpenes, not previously employe ...
DOI:
10.1016/j.chroma.2020.461044

38. Ultra-performance liquid chromatography tandem mass-spectrometry (UPLC–MS/MS) for the rapid, simultaneous analysis of thiamin, riboflavin, flavin adenine dinucleotide, nicotinamide and pyridoxal in human milk

Author:
Daniela Hampel; Emily R. York; Lindsay H. Allen
Source:
Journal of chromatography 2012 v.903 no. pp. 7-13
ISSN:
1570-0232
Subject:
acetonitrile; breast milk; ethyl ether; flavin-adenine dinucleotide; monitoring; nicotinamide; pyridoxal; stable isotopes; tandem mass spectrometry; thiamin; trichloroacetic acid; ultra-performance liquid chromatography
Abstract:
... A novel, rapid and sensitive ultra-performance liquid-chromatography tandem mass spectrometry (UPLC–MS/MS) method for the simultaneous determination of several B-vitamins in human milk was developed. Resolution by retention time or multiple reaction monitoring (MRM) for thiamin, riboflavin, flavin adenine dinucleotide (FAD), nicotinamide and pyridoxal (PL) has been optimized within 2min using a gr ...
DOI:
10.1016/j.jchromb.2012.06.024