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You searched for: Author "Song, Fengrui" Remove constraint Author: "Song, Fengrui" Journal Journal of chromatography Remove constraint Journal: Journal of chromatography
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1. Comprehensive investigation of in-vivo ingredients and action mechanism of iridoid extract from Gardeniae Fructus by liquid chromatography combined with mass spectrometry, microdialysis sampling and network pharmacology

Author:
Song, Fengrui,   et al.   ; Zhang, Xueju; Pi, Zifeng; Zheng, Zhong; Liu, Zhiqiang;     Show all 5 Authors
Source:
Journal of chromatography 2018 v.1076 pp. 70-76
ISSN:
1570-0232
Subject:
Oriental traditional medicine; alpha-glucosidase; binding capacity; fruits; ingredients; liquid chromatography; liquids; mass spectrometry; mechanism of action; metabolites; microdialysis; oral administration; pharmacology; proteins; prototypes; rats
Abstract:
... Gardeniae Fructus is a widely used Traditional Chinese Medicines in treating various diseases. However, the absorbed components and metabolites of its main bioactive iridoid ingredients from iridoid extract of the fruits of Gardeniae Fructus in rat plasma need further study. In this study, a systematic method based on ultra-performance liquid chromatography-quadrupole-time-of-flight/mass spectrome ...
DOI:
10.1016/j.jchromb.2018.01.023

2. Simultaneous quantification method for comparative pharmacokinetics studies of two major metabolites from geniposide and genipin by online mircrodialysis-UPLC–MS/MS B Analytical technologies in the biomedical and life sciences

Author:
Song, Fengrui,   et al.   ; Zhang, Xueju; Liu, Shu; Pi, Zifeng; Liu, Zhiqiang;     Show all 5 Authors
Source:
Journal of chromatography 2017 v.1041-1042 pp. 11-18
ISSN:
1570-0232
Subject:
animal disease models; blood; diabetes; herbal medicines; liquid chromatography; mass spectrometry; metabolites; microdialysis; pharmacokinetics; quantitative analysis; rats; toxicity
Abstract:
... Genipin-1-o-glucuronic acid and genipin-monosulfate are two major metabolites from geniposide and genipin. Based on diabetic rat model, we developed a simultaneous quantification method to investigate their comparative pharmacokinetics by online mircrodialysis-ultra performance liquid chromatography–mass spectrometry (MD-UPLC–MS/MS) without their standard compounds. Online microdialysis sampling c ...
DOI:
10.1016/j.jchromb.2016.12.010

3. Online monitoring of astragaloside II metabolism using a homemade cultural device coupled with microdialysis and ultra-performance liquid chromatography–mass spectrometry B Analytical technologies in the biomedical and life sciences

Author:
Song, Fengrui,   et al.   ; Li, Xue; Pi, Zifeng; Liu, Shu; Wang, Wei; Liu, Zhiqiang;     Show all 6 Authors
Source:
Journal of chromatography 2017 v.1063 pp. 141-148
ISSN:
1570-0232
Subject:
bacteria; biotransformation; equipment; fermentation; intestinal microorganisms; mass spectrometry; microbial communities; microdialysis; monitoring; ultra-performance liquid chromatography
Abstract:
... A new system was described for the online monitoring of astragaloside II (AII) metabolism in intestinal microbial community. The system was based on a homemade cultural device coupled with microdialysis (MD) and ultra-performance liquid chromatography–mass spectrometry (UPLC–MS). Main improvements include a simplified anaerobic incubator enabling the experiment to be conducted in ambient atmospher ...
DOI:
10.1016/j.jchromb.2017.08.012

4. A non-target urinary and serum metabolomics strategy reveals therapeutical mechanism of Radix Astragali on adjuvant-induced arthritis rats B Analytical technologies in the biomedical and life sciences

Author:
Song, Fengrui,   et al.   ; Xu, Tengfei; Feng, Guifang; Zhao, Bing; Zhao, Jiadi; Pi, Zifeng; Liu, Shu; Liu, Zhiqiang;     Show all 8 Authors
Source:
Journal of chromatography 2017 v.1048 pp. 94-101
ISSN:
1570-0232
Subject:
biomarkers; blood serum; chromatography; citrates; fatty acid metabolism; herbal medicines; inflammation; interleukin-1beta; metabolomics; multivariate analysis; oxidative stress; phenylalanine; pyridoxine; rats; rheumatoid arthritis; superoxide dismutase; therapeutics; tryptophan; tumor necrosis factor-alpha; urine; China
Abstract:
... Radix Astragali has been used traditionally in China to treat rheumatoid arthritis (RA) in formulas. In this paper, we conducted a holistic evaluation of Radix Astragali acted on adjuvant-induced arthritis (AIA) rats by urinary and serum metabolomic studies. Histological results and hind paw swelling were used to assess the joint damage, while the levels of IL-1β, TNF-α, SOD and MDA in serum were ...
DOI:
10.1016/j.jchromb.2017.01.040

5. Bioactive heterocyclic alkaloids with diterpene structure isolated from traditional Chinese medicines B Analytical technologies in the biomedical and life sciences

Author:
Song, Fengrui,   et al.   ; Xu, Tengfei; Liu, Shu; Meng, Lulu; Pi, Zifeng; Liu, Zhiqiang;     Show all 6 Authors
Source:
Journal of chromatography 2016 v.1026 pp. 56-66
ISSN:
1570-0232
Subject:
Aconitum; Consolida; Delphinium; Oriental traditional medicine; analgesics; bioactive compounds; biotransformation; chromatography; diterpenoid alkaloids; herbal medicines; medicinal properties; metabolism
Abstract:
... The diterpenoid alkaloids as one type of heterocyclic alkaloids have been found in many traditional herbal medicines, such as genus Consolida, Aconitum, and Delphinium (Ranunculaceae). Pharmacological researches have indicated that many diterpenoid alkaloids are the main bioactive components which have analgesic, anti-inflammatory, anti-microbial, anti-tumor, cardiotonic, and anti-arrhythmic activ ...
DOI:
10.1016/j.jchromb.2015.09.023

6. A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectrometry

Author:
Song, Fengrui,   et al.   ; Wang, Lu; Liu, Shu; Zhang, Xueju; Xing, Junpeng; Liu, Zhiqiang;     Show all 6 Authors
Source:
Journal of chromatography 2016 v.1452 pp. 47-57
ISSN:
0021-9673
Subject:
Gardenia jasminoides; carotenoids; electrospray ionization mass spectrometry; flavonoids; fruits; herbal medicines; high performance liquid chromatography; iridoids; isomers; monoterpenoids; phenolic acids; porous media; reversed-phase liquid chromatography; tandem mass spectrometry; triterpenoids
Abstract:
... In this paper, an analysis strategy integrating macroporous resin (AB-8) column chromatography and high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) combined with ion mobility spectrometry (IMS) was proposed and applied for identification and structural characterization of compounds from the fruits of Gardenia jasminoides. The extracts of G. j ...
DOI:
10.1016/j.chroma.2016.05.026

7. Multi-residue method for fast determination of pesticide residues in plants used in traditional chinese medicine by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry

Author:
Song, Fengrui,   et al.   ; Chen, Lina; Liu, Zhiqiang; Zheng, Zhong; Xing, Junpeng; Liu, Shuying;     Show all 6 Authors
Source:
Journal of chromatography 2012 v.1225 pp. 132-140
ISSN:
0021-9673
Subject:
Oriental traditional medicine; cleaning; guidelines; herbal medicines; monitoring; pesticide residues; pesticides; quality control; tandem mass spectrometry; ultra-performance liquid chromatography
Abstract:
... An ultra-high-performance liquid chromatographic–tandem mass spectrometry (UHPLC–MS/MS) method for the simultaneous quantification and identification of 116 pesticide residues which were most widely used in plants used in Traditional Chinese Medicine (TCM) in 15min has been developed and validated. Samples were extracted and cleaned up with modified QuEChERS method and detected by UHPLC–MS/MS unde ...
DOI:
10.1016/j.chroma.2011.12.071