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- Chowdhury, Pallabita; Nagesh, Prashanth K.B.; Hatami, Elham; Wagh, Santosh; Dan, Nirnoy; Tripathi, Manish K.; Khan, Sheema; Hafeez, Bilal B.; Meibohm, Bernd; Chauhan, Subhash C.; Jaggi, Meena; Yallapu, Murali M.
- Journal of colloid and interface science 2019 v.535 pp. 133-148
- Fourier transform infrared spectroscopy; P-glycoproteins; Western blotting; X-ray diffraction; adverse effects; antineoplastic activity; bioassays; breast neoplasms; chemosensitization; drug therapy; drugs; encapsulation; liquid chromatography; lung neoplasms; microarray technology; nanoparticles; neoplasm cells; paclitaxel; pharmacokinetics; screening; tandem mass spectrometry; tannins; thermogravimetry; tubulin; zeta potential
- ... Paclitaxel (PTX) is a gold standard chemotherapeutic agent for breast, ovarian, pancreatic and non-small cell lung carcinoma. However, in clinical use PTX can have adverse side effects or inadequate pharmacodynamic parameters, limiting its use. Nanotechnology is often employed to reduce the therapeutic dosage required for effective therapy, while also minimizing the systemic side effects of chemot ...
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