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- Kulkarni, Raghavendra V.; Boppana, Rashmi; Krishna Mohan, G.; Mutalik, Srinivas; Kalyane, Navanath V.
- Journal of colloid and interface science 2012 v.367 no.1 pp. 509-517
- Fourier transform infrared spectroscopy; X-ray diffraction; acrylamides; alkaline hydrolysis; crosslinking; differential scanning calorimetry; gastric mucosa; gelation; hemorrhage; histopathology; hydrocolloids; in vivo studies; intestines; kappa carrageenan; ketoprofen; nitrogen; pH; polyacrylamide; polymerization; rats; scanning electron microscopy; sodium alginate; thermogravimetry
- ... In the present work, we synthesized pH-responsive interpenetrating network (IPN) hydrogel beads of polyacrylamide grafted κ-carrageenan (PAAm-g-CG) and sodium alginate (SA) for targeting ketoprofen to the intestine. The PAAm-g-CG was synthesized by free radical polymerization followed by alkaline hydrolysis under nitrogen gas. The PAAm-g-CG was characterized by elemental analysis, FTIR spectroscop ...