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- Kontturi, Leena-Stiina; Yliperttula, Marjo; Toivanen, Pyry; Määttä, Antti; Määttä, Ann-Marie; Urtti, Arto
- Journal of controlled release 2011 v.152 no.3 pp. 376-381
- cell viability; epithelial cells; in vivo studies; microencapsulation; prices; proteins; vascular endothelial growth factor receptor-1
- ... Microencapsulated and genetically engineered cells may be used for prolonged delivery of therapeutically active proteins. The objective of this study was to develop a simple, inexpensive and flexible laboratory-scale device for the production of cell microcapsules, especially capsules of small diameter (<300μm). Many microencapsulation devices are expensive, difficult to assemble and to use, and o ...
- Dash, Biraja C.; Mahor, Sunil; Carroll, Oliver; Mathew, Asha; Wang, Wenxin; Woodhouse, Kimberly A.; Pandit, Abhay
- Journal of controlled release 2011 v.152 no.3 pp. 382-392
- biocompatibility; cell viability; crosslinking; elastase; genes; luciferase; nanomaterials; plasmids; polypeptides; protein-glutamine gamma-glutamyltransferase
- ... Self-assembly driven processes can be utilized to produce a variety of nanostructures useful for various in vitro and in vivo applications. Characteristics such as size, stability, biocompatibility, high therapeutic loading and controlled delivery of these nanostructures are particularly crucial in relation to in vivo applications. In this study, we report the fabrication of tunable monodispersed ...