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- Currier, Jenna M.; Douillet, Christelle; Drobná, Zuzana; Stýblo, Miroslav
- Journal of environmental sciences (China) 2016 v.49 pp. 104-112
- adipose tissue; adverse effects; arsenic; arsenites; blood; brain; drinking water; heart; intestinal microorganisms; intestines; kidneys; liver; lungs; males; metabolites; methylation; methyltransferases; mice; oxidation; pancreas; toxicity
- ... Arsenic methyltransferase (As3mt) catalyzes the conversion of inorganic arsenic (iAs) to its methylated metabolites, including toxic methylarsonite (MAsᴵᴵᴵ) and dimethylarsinite (DMAsᴵᴵᴵ). Knockout (KO) of As3mt was shown to reduce the capacity to methylate iAs in mice. However, no data are available on the oxidation states of As species in tissues of these mice. Here, we compare the oxidation sta ...
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