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You searched for: Journal name Journal of ethnopharmacology Remove constraint Journal name: Journal of ethnopharmacology Publication year rev 7978-2022 Remove constraint Publication year rev: 7978-2022 Source 2022 v.283 Remove constraint Source: 2022 v.283
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1. Anti-depressive effects of Jiao-Tai-Wan on CORT-induced depression in mice by inhibiting inflammation and microglia activation

Author:
Guiqin Bai; Yiqi Qiao; Po-Chieh Lo; Lei Song; Yuna Yang; Lining Duan; Sufen Wei; Min Li; Shuiqing Huang; Beiping Zhang; Qi Wang; Cong Yang
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114717
ISSN:
0378-8741
Subject:
Oriental traditional medicine; RNA; anxiety; bioactive compounds; blood serum; corticosterone; forced swimming test; genes; high performance liquid chromatography; inflammation; interleukin-6; lipopolysaccharides; macrophages; mice; neuroglia; neurons; neurotransmitters; sequence analysis; sleep disorders; therapeutics; transcriptome; transcriptomics
Abstract:
... Jiao-Tai-Wan (JTW) is a very famous traditional Chinese medicine formula for the treatment of psychiatric disorders, especially in anxiety, insomnia and depression. However, its molecular mechanism of treatment remains indistinct.We aimed to reveal the action mechanism of JTW on anti-depression via inhibiting microglia activation and pro-inflammatory response both in vivo and in vitro.The corticos ...
DOI:
10.1016/j.jep.2021.114717

2. Anti-nociceptive effects of ECa 233 a standardized extract of Centella asiatica (L.) Urban on chronic neuropathic orofacial pain in mice

Author:
Ananya Buapratoom; Aree Wanasuntronwong; Onrawee Khongsombat; Mayuree H. Tantisira
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114737
ISSN:
0378-8741
Subject:
Centella asiatica; Parkinson disease; analgesic effect; calcitonin; clinical trials; cognition; ganglia; locomotion; mechanism of action; nerve tissue; pain; pharmacokinetics; sedatives; somatosensory disorders; synergism; toxicity; traditional medicine
Abstract:
... ECa 233 is a standardized extract of Centella asiatica (L.) Urban, a herb traditionally used to treat a number of diseases including neurological disorders. Accordingly, ECa 233 showed benefits on animal models of cognitive deficits, chronic stress and Parkinson's disease. Analgesic activity of ECa 233 was shown in Tail's flick test in rodent and relieving aphthous ulcer pain in man. Moreover, acu ...
DOI:
10.1016/j.jep.2021.114737

3. Combination of Compound Kushen Injection and cisplatin shows synergistic antitumor activity in p53-R273H/P309S mutant colorectal cancer cells through inducing apoptosis

Author:
Xingkang Wu; Yufang Lu; Xuemei Qin
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114690
ISSN:
0378-8741
Subject:
Oriental traditional medicine; Western blotting; adjuvants; antineoplastic activity; apoptosis; cisplatin; colorectal neoplasms; drug therapy; fluorouracil; genes; genetic variation; mutants; necroptosis; prognosis; transcription (genetics); transcriptomics
Abstract:
... Colorectal cancer (CRC) is one type of worldwide popular and refractory tumors. Compound Kushen Injection (CKI) is a frequently applied traditional Chinese medicine formula as an adjuvant drug for the chemotherapy of CRC. P53 is the most commonly mutated gene in CRC, accounting for the development, malignant and prognosis progression of CRC. However, effect of CKI on the therapeutic efficacy of p5 ...
DOI:
10.1016/j.jep.2021.114690

4. Comparative evaluation of anti-inflammatory activity between n-butanol fraction, leaf and stem methanolic extract obtained from Olaxpsittacorum

Author:
Raja Majumder; Moonmun Dhara; Lopamudra Adhikari; Amitav Panigrahi
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114697
ISSN:
0378-8741
Subject:
albino; anemia; anti-inflammatory activity; antineoplastic activity; body weight; butanol; chloroform; constipation; diabetes; diclofenac; diosgenin; drug development; edema; fractionation; gallic acid; inflammation; leaf extracts; leaves; microscopes; models; pain; palmitic acid; psoriasis; quercetin; silica; tannins; traditional medicine
Abstract:
... Olax psittacorum (Lam.) Vahl. traditionally used by the tribal communities of ‘INDIA’ to heal conditions such as pain, psoriasis, mouthulcer, anemia, constipation as well as diabetes followed by scientific evidences like antipyretic, anti-inflammatory, antimicrobial, anti-viral, and anti-cancer property too.Solvent fractionation process by using chloroform, distilled water and n-butanol has been d ...
DOI:
10.1016/j.jep.2021.114697

5. Compound Tongluo Decoction inhibits endoplasmic reticulum stress-induced ferroptosis and promoted angiogenesis by activating the Sonic Hedgehog pathway in cerebral infarction

Author:
Zhen Hui; Sulei Wang; Jianxiang Li; Jingqing Wang; Zhennian Zhang
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114634
ISSN:
0378-8741
Subject:
Oriental traditional medicine; Western blotting; angiogenesis; animal models; antagonists; brain; butyric acid; endoplasmic reticulum; endoplasmic reticulum stress; ferroptosis; fluorescent antibody technique; immunohistochemistry; infarction; malondialdehyde; reactive oxygen species; superoxide dismutase
Abstract:
... Cerebral infarction is one of the most common types of cerebrovascular diseases that threaten people's health. Compound Tongluo Decoction (CTLD), a traditional Chinese medicine formula, has various pharmacological activities, including the alleviation of cerebral infarction symptoms.Aim of the study: This study aims to explore the potential mechanism by which CTLD alleviates cerebral infarction.Mi ...
DOI:
10.1016/j.jep.2021.114634

6. Crosstalk of LncRNA HOTAIR and SP1-mediated repression of PDK1 contributes to β-Elemene-inhibited proliferation of hepatocellular carcinoma cells

Author:
JingJing Wu; XiaoJuan Tang; Yao Shi; ChangJu Ma; Hongyu Zhang; Junhong Zhang; Yue Lu; Jianan Wei; Li Li; Ling Han
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114456
ISSN:
0378-8741
Subject:
Curcuma; cell growth; cell proliferation; flow cytometry; hepatoma; liver; plasmids; prognosis; traditional medicine; transfection
Abstract:
... Hepatocellular carcinoma (HCC) is a liver malignancy which lacks effective treatment and has a poor prognosis. β-Elemene refers to a natural Curcuma wenyujin-derived single molecular entity, which exhibits various biological activities, and is especially well-known for it's antitumor properties.LncRNA HOTAIR, SP1, and PDK1 have displayed oncogenic roles in many tumors, participating in the initiat ...
DOI:
10.1016/j.jep.2021.114456

7. Daphnes Cortex and its licorice-processed products suppress inflammation via the TLR4/NF-κB/NLRP3 signaling pathway and regulation of the metabolic profile in the treatment of rheumatoid arthritis

Author:
Xianglong Meng; Xiaoyan Zhang; Xiaojuan Su; Xiaoqin Liu; Kele Ren; Chenxu Ning; Qi Zhang; ShuoSheng Zhang
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114657
ISSN:
0378-8741
Subject:
Daphne; Oriental traditional medicine; animal models; blood serum; cortex; cytokines; inflammation; lipopolysaccharides; macrophages; mass spectrometry; metabolites; metabolomics; metalloproteinases; rats; rheumatoid arthritis; skin irritation; therapeutics; vascular endothelial growth factors; China
Abstract:
... Daphnes Cortex (Daphne Giraldii Nitsche, DGN) is a popular traditional Chinese herbal medicine for traumatic injuries and rheumatoid arthritis (RA) in the Shaanxi and Gansu provinces of China. Due to skin irritation caused by raw DGN (RDGN), licorice-processed DGN products are usually used in clinical practice. However, the efficacy and mechanisms of action between DGN and its licorice-processed D ...
DOI:
10.1016/j.jep.2021.114657

8. Diaphragma juglandis extracts modifies the gut microbiota during prevention of type 2 diabetes in rats

Author:
Feng Zhang; Dan Chen; Liming Zhang; Qingyujing Zhao; Yage Ma; Xi Zhang; Shenglan Zhao; Chaoyin Chen
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114484
ISSN:
0378-8741
Subject:
Juglans regia; Klebsiella; Lactobacillaceae; Rikenella; alanine transaminase; aspartate transaminase; blood glucose; blood proteins; blood serum; catalase; cholesterol; feces; genes; glucose tolerance tests; glycosylation; high density lipoprotein; high fat diet; inflammation; insulin; insulin resistance; intestinal microorganisms; lipid metabolism; lipopolysaccharides; liver; low density lipoprotein; malondialdehyde; necrosis; neoplasms; nitric oxide; noninsulin-dependent diabetes mellitus; oxidative stress; pancreas; protective effect; rats; superoxide dismutase; traditional medicine; walnuts; wood
Abstract:
... The diaphragma juglandis (DJ) comes from the wooden septum in the core of Juglans regia L, also known as the walnut septum. In Iranian traditional medicine, walnut distraction wood was widely used in the treatment of diabetes. However, there is a lack of research data on the mechanism of DJ against diabetes.Aim of the study: To explore the protective effect of diaphragma juglandis extract (DJE) on ...
DOI:
10.1016/j.jep.2021.114484

9. Effect of a combination of Korean red ginseng extract and probiotics on the prevention of atopic dermatitis in a murine model

Author:
Se Hoon Lee; Jeesuk Yu; Sang Hyun Cho
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114687
ISSN:
0378-8741
Subject:
Panax ginseng; animal models; anti-allergic agents; atopic dermatitis; blood serum; cyclosporine; ears; gene expression; immunoglobulin E; immunohistochemistry; interleukin-4; probiotics; traditional medicine; Korean Peninsula
Abstract:
... Panax ginseng C.A.Mey. (Korea red ginseng) has been used in Asia to treat inflammatory skin diseases. Recently, Korea red ginseng (KRG) is emerging as a good candidate for treating atopic dermatitis (AD) because of its anti-allergic and anti-inflammatory effects.Despite much effort, no systemic prevention strategy has been established for AD currently. Therefore, the aim of this study was to deter ...
DOI:
10.1016/j.jep.2021.114687

10. Effects of the Tibetan medicine Byur dMar Nyer lNga Ril Bu on Alzheimer's disease in mice models

Author:
Jokyab Tsering; Qianqian Chen; Honghong Li; Yanan Han; Jinpeng Wu; Huijuan Yin; Jiashen Hu; Siying Su; Xiafei Shi; Xianda Hu; Bochen Che
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114724
ISSN:
0378-8741
Subject:
Alzheimer disease; Oriental traditional medicine; bacteria; cognition; fatty acids; genetically modified organisms; glutamine; hippocampus; intestinal microorganisms; memory; neuroglia; oral administration; oxidative phosphorylation; peroxisome proliferator-activated receptors; phagocytosis; protein synthesis; proteomics
Abstract:
... Byur dMar Nyer lNga Ril Bu (BdNlRB) is a classic Tibetan medicine prescription for treating " white vein disease". Alzheimer's disease (AD) is a chronic degenerative disease of the central nervous system, characterized by distinct "white vein disease". In the absence of effective drugs for AD, BdNlRB may be a possible treatment for AD.To verify the therapeutic effect and possible mechanism of the ...
DOI:
10.1016/j.jep.2021.114724

11. Efficacy and safety of Duhuo Jisheng Decoction add-on bisphosphonate medications in patients with osteoporosis: A meta-analysis of randomized controlled trials

Author:
Chung-Yu Huang; Ciao-Jhih Cheng; Wen-Fei Chiou; Wei-Chiao Chang; Yi-No Kang; Mei-Hsien Lee
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114732
ISSN:
0378-8741
Subject:
bone density; experimental design; meta-analysis; osteoporosis; pain; relative risk; statistical models; systematic review; traditional medicine
Abstract:
... Duhuo Jisheng Decoction (DHJSD) is the most frequently prescribed herbal formula for the treatment of osteoporosis. However, efficacy and safety of DHJSD add-on bisphosphonate medications remain unclear.The purpose of this study was to reveal efficacy and safety of DHJSD add-on bisphosphonate medications in patients with osteoporosis through a systematic review with meta-analysis of randomized con ...
DOI:
10.1016/j.jep.2021.114732

12. Elucidating the estrogen-like effects and biocompatibility of the herbal components in the Qing' E formula

Author:
Jing-lin Xiong; Xin-yin Cai; Zi-jia Zhang; Qi Li; Qiang Zhou; Zheng-tao Wang
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114735
ISSN:
0378-8741
Subject:
Eucommia ulmoides; Juglans regia; Oriental traditional medicine; Psoralea; anorexia; antioxidant activity; aromatase; atrophy; biocompatibility; blood serum; climacteric fruits; cortex; estrogens; garlic; immunohistochemistry; kidneys; lipid metabolism; luciferase; malondialdehyde; muscles; neurotransmitters; osteoporosis; ovariectomy; pharmacodynamics; plant estrogens; quantitative polymerase chain reaction; reporter genes; rhizomes; superoxide dismutase; toxicity; uterus; weight gain
Abstract:
... The Qing' E Formula (QEF) is a compound preparation that was originally recorded in the ‘Prescriptions of the Bureau of Taiping People's Welfare Pharmacy’ during the Song Dynasty (10th century CE). It consists of four Chinese medicinal herbs, Eucommiae Cortex (Eucommia ulmoides), Psoraleae Fructus (Psoralea corylifolium), Juglandis Semen (Juglans regia), and Garlic Rhizoma. According to traditiona ...
DOI:
10.1016/j.jep.2021.114735

13. Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. – A critically endangered medicinal plant of the western Himalaya

Author:
Shalika Rathore; Yog Raj; Pritam Debnath; Manish Kumar; Rakesh Kumar
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114613
ISSN:
0378-8741
Subject:
Inula racemosa; antipyretics; antiseptics; aphrodisiacs; chest; essential oils; ethnobotany; genomics; glycosides; health services; issues and policy; liver; medicinal plants; metabolites; pain; parasympatholytics; phytosterols; respiratory system; respiratory tract diseases; stomach ulcers; surveys; toxicity; traditional medicine; Himalayan region
Abstract:
... Inula racemosa Hook. f., is a critically endangered perennial herb distributed throughout the Himalaya; commercially useful in pharmaceutical products mainly because of its expectorant, antispasmodic, hypotensive, anti-inflammatory, carminative, thermogenic, digestive, cardiotonic, acrid, alexipharmic, anodyne, aphrodisiac, febrifuge, and antiseptic properties. The roots including rhizomes of the ...
DOI:
10.1016/j.jep.2021.114613

14. Genotoxicity, nitric oxide level modulation and cardio-protective potential of Kalanchoe Integra Var. Crenata (Andr.) Cuf Leaves in murine models

Author:
Isaac Julius Asiedu-Gyekye; Emmanuel Arhin; Stella Amaaba Arthur; Benoit Banga N'guessan; Seth Kwabena Amponsah
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114640
ISSN:
0378-8741
Subject:
Kalanchoe deficiens; air drying; alanine transaminase; alkaline phosphatase; aspartate transaminase; blood; blood pressure; cancer therapy; cardiotoxicity; catalase; comet assay; creatine kinase; doxorubicin; ethanol; females; genotoxicity; glutathione; heart failure; high performance liquid chromatography; histology; histopathology; lactate dehydrogenase; leaf extracts; mice; mutagens; nitric oxide; superoxide dismutase; traditional medicine; vitamin E
Abstract:
... Advancement in cancer therapy has improved survival among patients. However, use of anticancer drugs like anthracyclines (e.g., doxorubicin) is not without adverse effects. Notable among adverse effects of doxorubicin (DOX) is cardiotoxicity, which ranges from mild transient blood pressure changes to potentially serious heart failure. Anecdotal reports suggest that Kalanchoe integra (KI) may have ...
DOI:
10.1016/j.jep.2021.114640

15. Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome

Author:
Guo-Qing Zhou; Gang Chen; Juan Yang; Wen-yi Qin; Jia Ping
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114707
ISSN:
0378-8741
Subject:
DNA; Oriental traditional medicine; Western blotting; arthritis; aspartic acid; caspase-1; chemotaxis; enzyme-linked immunosorbent assay; inflammasomes; inflammation; interleukin-6; monocytes; neutrophils; oligomerization; peritonitis; precipitin tests
Abstract:
... Guizhi-Shaoyao-Zhimu decoction (GSZD), a classical traditional Chinese medicine (TCM) prescription, is used empirically to treat various types of arthritis in TCM clinical practice. However, the underlying mechanisms of GSZD on gouty inflammation are not totally elucidated.The purpose of this study is to investigate the effects of GSZD on peritoneal recruitment of neutrophils, production of proinf ...
DOI:
10.1016/j.jep.2021.114707

16. In-vitro anti-Helicobacter pylori activity and preliminary mechanism of action of Canarium album Raeusch. fruit extracts

Author:
Jiahui Yan; Chang Peng; Pengting Chen; Weijia Zhang; Cheng Jiang; Shuyi Sang; Weixing Zhu; Yuemei Yuan; Yanjun Hong; Meicun Yao
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114578
ISSN:
0378-8741
Subject:
Canarium album; Helicobacter pylori; Oriental traditional medicine; antibacterial properties; antibiotic resistance; colorimetry; cough; crabs; electron microscopy; ethyl acetate; fish; fruits; heat; high performance liquid chromatography; liquid-liquid extraction; mechanism of action; pharyngitis; phytochemicals; ultrasonics; urease; virulence
Abstract:
... Canarium album Raeusch. belongs to the Burseraceae family. Its ripe fruits, known as Qing Guo (QG) in Traditional Chinese Medicine (TCM), are used to treat sore throat, cough, and fish or crab poisoning. QG was reported to have antibacterial activity, and it exerted excellent anti-Helicobacter pylori (H. pylori) activity in our screening of abundant TCM. However, few studies have reported its anti ...
DOI:
10.1016/j.jep.2021.114578

17. Inhibition of enzymatic activities of Bothrops asper snake venom and docking analysis of compounds from plants used in Central America to treat snakebite envenoming

Author:
Patricia Saravia-Otten; Rosario Hernández; Nereida Marroquín; Jaime A. Pereañez; Lina M. Preciado; Allan Vásquez; Gabriela García; Federico Nave; Lorena Rochac; Vicente Genovez; Max Mérida; Sully M. Cruz; Nohemí Orozco; Armando Cáceres; José M. Gutiérrez
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114710
ISSN:
0378-8741
Subject:
Bothrops; Eryngium foetidum; Pimenta dioica; acetone; active sites; coagulants; coumarins; ethyl acetate; flavonoids; hydrophobicity; metalloproteinases; phospholipases; proteolysis; public health; saponins; secondary metabolites; sesquiterpenoid lactones; snake bites; snake venoms; snakes; toxicity; toxicology; traditional medicine; Costa Rica; Guatemala; Nicaragua
Abstract:
... Snakebite envenoming is a public health problem of high impact in Central America. Bothrops asper, known as barba amarilla, terciopelo, and equis, is the snake species responsible for most snakebites in Central America. In this region, there is a long-standing tradition on the use of plants in the management of snakebites, especially in indigenous communities. Ethnomedical use of Eryngium foetidum ...
DOI:
10.1016/j.jep.2021.114710

18. Integrated lipidomics, transcriptomics and network pharmacology analysis to reveal the mechanisms of Danggui Buxue Decoction in the treatment of diabetic nephropathy in type 2 diabetes mellitus

Author:
Lili Sun; Zhigang Yang; Wei Zhao; Qin Chen; Haiying Bai; Shanshan Wang; Li Yang; Chunmei Bi; Yanbin Shi; Yingqian Liu
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114699
ISSN:
0378-8741
Subject:
Angelica sinensis; astragalosides; biomarkers; diabetic nephropathy; ferulic acid; forage; formononetin; inflammation; insulin resistance; kaempferol; kidneys; lipidomics; medicinal properties; metabolites; mice; noninsulin-dependent diabetes mellitus; phosphatidylcholines; phosphatidylethanolamines; phosphorylation; quantitative analysis; sphingolipids; statistical analysis; streptozotocin; therapeutics; transcriptomics
Abstract:
... Danggui Buxue Decoction (DBT) is classical prescriptions, which contains two Traditional Chinese Medicines of Angelicae sinensis radix and Astragali radix. According to the preliminary work of our laboratory and numerous studies, it has been found that DBT has a therapeutic effect on diabetic nephropathy (DN). However, the mechanisms underlying its action remain unclear.The aim of this study was t ...
DOI:
10.1016/j.jep.2021.114699

19. Invasive alien plants and weeds in South Africa: A review of their applications in traditional medicine and potential pharmaceutical properties

Author:
L.J. McGaw; A.G. Omokhua-Uyi; J.F. Finnie; J. Van Staden
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114564
ISSN:
0378-8741
Subject:
Asteraceae; Fabaceae; Solanaceae; bioactive properties; commercialization; ecosystems; ethnobotany; invasive species; phytochemicals; secondary metabolites; traditional medicine; South Africa
Abstract:
... Traditional pharmacopoeias are constantly evolving and adapting, hence the assimilation of alien plants and weeds into traditional systems of healing. Invasive plants are detrimental to the ecosystem, however they are also potential sources of secondary metabolites with useful biological activities.The aim of this review was to investigate published reports of traditional use and biological activi ...
DOI:
10.1016/j.jep.2021.114564

20. Isatidis Radix and Isatidis Folium: A systematic review on ethnopharmacology, phytochemistry and pharmacology

Author:
Jiao Chen; Zongping Zhu; Tianhui Gao; Yi Chen; Qingsong Yang; Chaomei Fu; Yaning Zhu; Fang Wang; Wan Liao
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114648
ISSN:
0378-8741
Subject:
Internet; Oriental traditional medicine; Orthomyxoviridae; Respiratory syncytial virus; adenosine; antioxidants; cough; databases; erucic acid; fever; heart; herpes simplex; immunity; immunomodulators; influenza; lignans; lungs; pharyngitis; phytochemicals; reproduction; stomach; systematic review; taste; therapeutics; toxicity; viruses
Abstract:
... Isatidis Radix (called Banlangen, BLG in Chinese) and Isatidis Folium (called Daqingye, DQY in Chinese) are common traditional edible-medicinal herbs in detoxifying for thousands of years, have been traditionally applied in traditional Chinese medicine for centuries. Both of them are bitter in taste, coolness in nature, acting on the heart and stomach channels. They are often used to treat influen ...
DOI:
10.1016/j.jep.2021.114648