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- Yan, Xu; Wu, Hongjin; Ren, Jianxun; Liu, Yuna; Wang, Shengqi; Yang, Jiyuan; Qin, Shuyan; Wu, Delin
- Journal of ethnopharmacology 2018 v.227 pp. 105-112
- rats, etc ; Aconitum carmichaelii; Oriental traditional medicine; Panax ginseng; Western blotting; animal models; apoptosis; blood sampling; blood serum; brain; cardiac output; cardiomyocytes; caspase-3; coronary vessels; echocardiography; heart failure; microRNA; natriuretic peptides; proteins; surgery; Show all 20 Subjects
- ... Shenfu decoction consists of the water extract from the dried root or rootstalk of Panax ginseng C. A. Mey (Asian ginseng) and the lateral root of Aconitum carmichaeli Debx (Fuzi, Heishunpian in Chinese). Shenfu Formula has been used as a folk Chinese medicine for thousands of years. Recent studies have shown that Shenfu injection can enhance cardiac function and regulate arrhythmia.Shenfu Formula ...
- Cao, Di; Xu, Chuncao; Xue, Yuanyuan; Ruan, Qingfeng; Yang, Bao; Liu, Zhongqiu; Cui, Hui; Zhang, Lei; Zhao, Zhongxiang; Jin, Jing
- Journal of ethnopharmacology 2018 v.227 pp. 18-28
- rats, etc ; Ilex pubescens; arachidonic acid; aspirin; bile acids; biochemical pathways; biomarkers; biosynthesis; blood serum; blood stasis; cardiovascular diseases; discriminant analysis; endothelial nitric oxide synthase; fibrinogen; high performance liquid chromatography; mass spectrometry; mechanism of action; metabolites; metabolomics; models; multivariate analysis; normal values; phospholipids; principal component analysis; prothrombin; therapeutics; thrombin; thromboplastin; thromboxanes; traditional medicine; ultra-performance liquid chromatography; Show all 31 Subjects
- ... Ilex pubescens Hook. et Arn (MDQ), a traditional Chinese herb, is used in the treatment of cardiovascular diseases. However, the mechanisms underlying the preventive effect of MDQ on blood stasis remain unclear.In this study, serum metabolomics integrated with a biochemical assay strategy were established to evaluate the preventive effect and mechanism of action of MDQ on rats with acute blood sta ...