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- Author:
- Moraes-Souza, Rafaianne Queiroz; Soares, Thaigra Sousa; Carmo, Nágilla Orleanne Lima; Damasceno, Débora Cristina; Campos, Kleber Eduardo; Volpato, Gustavo Tadeu
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 328-333
- ISSN:
- 0378-8741
- Subject:
- Croton urucurana; adverse effects; blood; body weight; cholesterol; enzyme activity; fetal development; food intake; heart; humans; latex; liver; plant extracts; pregnancy; progeny; protein content; rats; risk; tissues; toxicity; traditional medicine; women
- Abstract:
- ... Croton urucurana presents several beneficial pharmacological properties. In Brazil, women who intend to interrupt the pregnancy indiscriminately use extracts of this plant as an abortifacient agent.To evaluated the effect of aqueous extract of Croton urucurana latex on the maternal-fetal repercussions in rats.Pregnant rats were randomly distributed into four experimental groups: Control=treated wi ...
- DOI:
- 10.1016/j.jep.2016.10.061
-
https://dx.doi.org/10.1016/j.jep.2016.10.061
- Author:
- Abotsi, Wonder Kofi Mensah; Lamptey, Stanley Benjamin; Boakye-Gyasi, Eric; Woode, Eric
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 183-193
- ISSN:
- 0378-8741
- Subject:
- Albizia zygia; acetaminophen; analgesic effect; animal models; antagonists; atropine; diclofenac; fever; formalin test; morphine; naloxone; pain; rats; roots; somatosensory disorders; theophylline; traditional medicine
- Abstract:
- ... The root extract of Albizia zygia (DC.) J.F. Macbr. (Leguminosae-Mimosoideae) is traditionally used in the management of pain and fever. However, little scientific data exists in literature to support its use.The present study evaluated the anti-nociceptive and antipyretic properties of the hydroethanolic extract of the roots of Albizia zygia in animal models.The analgesic effects were investigate ...
- DOI:
- 10.1016/j.jep.2017.02.007
-
https://dx.doi.org/10.1016/j.jep.2017.02.007
- Author:
- Jiao, Yukun; Wang, Xueqian; Jiang, Xiang; Kong, Fansheng; Wang, Shumei; Yan, Chunyan
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 119-127
- ISSN:
- 0378-8741
- Subject:
- Morus alba; Oriental traditional medicine; Western blotting; alanine transaminase; animal disease models; bark; blood glucose; blood lipids; blood proteins; blood serum; fasting; glucose tolerance tests; glucose transporters; glycemic effect; high density lipoprotein cholesterol; high fat diet; histopathology; homeostasis; human health; insulin; kidneys; leaves; lipemic effect; lipid composition; liver; mulberries; noninsulin-dependent diabetes mellitus; pancreas; polyphenols; polysaccharides; rats; roots; signal transduction; sleep disorders; streptozotocin; triacylglycerols
- Abstract:
- ... Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are k ...
- DOI:
- 10.1016/j.jep.2017.02.003
-
https://dx.doi.org/10.1016/j.jep.2017.02.003
- Author:
- Kostić, Milica; Kitić, Dušanka; Petrović, Milica B.; Jevtović-Stoimenov, Tatjana; Jović, Marko; Petrović, Aleksandar; Živanović, Slavoljub
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 52-59
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Escherichia coli; Salvia sclarea; anti-inflammatory activity; antioxidant activity; body weight; fibroblasts; gingiva; gingivitis; high performance liquid chromatography; histopathology; inflammation; interleukin-1beta; interleukin-6; lipopolysaccharides; necrosis; periodontitis; rats; reactive oxygen species; resorption; rosmarinic acid; traditional medicine; tumor necrosis factor-alpha
- Abstract:
- ... Salvia sclarea L., clary, is an aromatic plant traditionally used in folk medicine for the treatment of various diseases and conditions. Although it has been primarily used as a stomachic, there are data on traditional use of S. sclarea as an agent against gingivitis, stomatitis and aphthae.The aim of the study was to examine the effect of the S. sclarea ethanolic extract on the lipopolysaccharide ...
- DOI:
- 10.1016/j.jep.2017.01.020
-
https://dx.doi.org/10.1016/j.jep.2017.01.020
- Author:
- Chithambo, Bertha; Noundou, Xavier Siwe; Krause, Rui W.M.
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 91-96
- ISSN:
- 0378-8741
- Subject:
- Fourier transform infrared spectroscopy; Morinda lucida; Plasmodium falciparum; Yellow fever virus; active ingredients; adenocarcinoma; antimalarials; bark; beta-sitosterol; campesterol; cell viability; cervix; children; cytotoxicity; humans; inhibitory concentration 50; lactate dehydrogenase; leaves; malaria; mass spectrometry; methanol; methylene chloride; nuclear magnetic resonance spectroscopy; parasites; roots; secondary metabolites; stigmasterol; thin layer chromatography; traditional medicine; trypanosomiasis; Africa
- Abstract:
- ... The roots, stem and leaves of Morinda lucida are used in some African countries as treatment against different types of fevers including yellow fever, malaria, trypanosomiasis and feverish conditions during child birth.To determine the in vitro cell toxicity and anti-malarial activity of the extracts of stem bark of M. lucida and to identify the secondary metabolites in the extract that may be res ...
- DOI:
- 10.1016/j.jep.2017.01.051
-
https://dx.doi.org/10.1016/j.jep.2017.01.051
- Author:
- Desai, Sharad; Babaria, Parth; Nakarani, Madhavi; Shah, Kunal; Paranjape, Archana
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 1-8
- ISSN:
- 0378-8741
- Subject:
- Hemidesmus indicus; acid phosphatase; acid tolerance; adverse effects; alkaline phosphatase; blood serum; body weight; bone resorption; bone strength; calcium; cholesterol; ethanol; females; femur; herbal medicines; histopathology; hydroxyproline; hypertrophy; mineralization; osteoporosis; ovariectomy; phosphorus; postmenopause; rats; tibia; traditional medicine; triacylglycerols; urine; uterus; vagina; vertebrae; India
- Abstract:
- ... Root of Hemidesmus indicus (L). R. Br., an herbal drug of India is traditionally used to prevent or treat female hormonal disturbance related disorders and assuaging symptoms of menopausal conditions.Lack of scientific data for potential use in bone loss, the present study was undertaken to investigate the effects of ethanol extract of Hemidesmus indicus root for osteoporosis in ovariectomised rat ...
- DOI:
- 10.1016/j.jep.2017.01.031
-
https://dx.doi.org/10.1016/j.jep.2017.01.031
- Author:
- Yang, Yi; Wang, Shuai; Bao, Yong-rui; Li, Tian-jiao; Yang, Guan-lin; Chang, Xin; Meng, Xian-sheng
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 175-182
- ISSN:
- 0378-8741
- Subject:
- Glycyrrhiza glabra; Glycyrrhiza uralensis; Oriental traditional medicine; RNA; amino acid metabolism; anti-ulcer activity; arachidonic acid; drugs; gene expression; genes; high performance liquid chromatography; histamine; inflammation; mass spectrometry; mechanism of action; metabolites; metabolomics; rats; reverse transcriptase polymerase chain reaction; rhizomes; statistical analysis; stomach; stomach ulcers; tissues; tryptophan; China
- Abstract:
- ... Glycyrrhiza is the dry root and rhizome of the leguminous plant, Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L., which was firstly cited in Shennong's Herbal Classic in Han dynasty and was officially listed in the Chinese Pharmacopoeia, has been widely used in China during the past millennia. Licoflavone is the major component of Glycyrrhiza with anti-ulcer activit ...
- DOI:
- 10.1016/j.jep.2017.01.053
-
https://dx.doi.org/10.1016/j.jep.2017.01.053
- Author:
- Zhou, Beixian; Yang, Zifeng; Feng, Qitong; Liang, Xiaoli; Li, Jing; Zanin, Mark; Jiang, Zhihong; Zhong, Nanshan
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 60-67
- ISSN:
- 0378-8741
- Subject:
- Influenza A virus; Influenza B virus; Strobilanthes; Western blotting; acetates; active ingredients; anti-inflammatory activity; antioxidants; antiviral properties; birds; chemokine CCL5; cytopathogenicity; dogs; epithelium; gene expression; genes; influenza; interleukin-6; interleukin-8; kidneys; luciferase; messenger RNA; plasmids; quantitative polymerase chain reaction; ribonucleoproteins; signal transduction; traditional medicine; transcription (genetics); transcription factor NF-kappa B; tumor necrosis factor-alpha; viral load; viruses
- Abstract:
- ... Baphicacanthus cusia root also names “Nan Ban Lan Gen” has been traditionally used to prevent and treat influenza A virus infections. Here, we identified a peptide derivative, aurantiamide acetate (compound E17), as an active compound in extracts of B. cusia root. Although studies have shown that aurantiamide acetate possesses antioxidant and anti-inflammatory properties, the effects and mechanism ...
- DOI:
- 10.1016/j.jep.2017.01.038
-
https://dx.doi.org/10.1016/j.jep.2017.01.038
- Author:
- Mohammadhosseini, Majid; Sarker, Satyajit D.; Akbarzadeh, Abolfazl
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 257-315
- ISSN:
- 0378-8741
- Subject:
- Achillea; chemical composition; databases; essential oils; ethnobotany; gastrointestinal system; hay fever; inflammation; medicinal properties; menstruation; phytopharmaceuticals; sedatives; tissue repair; traditional medicine; women
- Abstract:
- ... The Asteraceae (alt. Compositae) family incorporates a large number of flowering plants, which have been classified under ca. 1600 genera covering more than 23,000 species. The genus Achillea is one of the best-known genera of this family. The Achillea species are important for their uses in the chemical and pharmaceutical purposes, and traditional and folk medicines. From ethnobotanical point of ...
- DOI:
- 10.1016/j.jep.2017.02.010
-
https://dx.doi.org/10.1016/j.jep.2017.02.010
- Author:
- Hung, Kuo-Feng; Hsu, Ching-Ping; Chiang, Jen-Huai; Lin, Hung-Jen; Kuo, Yi-Ting; Sun, Mao-Feng; Yen, Hung-Rong
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 168-174
- ISSN:
- 0378-8741
- Subject:
- clinical trials; comorbidity; databases; drug therapy; herbal medicines; mortality; patients; radiotherapy; regression analysis; risk; stomach neoplasms; surgery; traditional medicine; Taiwan
- Abstract:
- ... Many patients with gastric cancer seek traditional medicine consultations in Asian countries. This study aimed to investigate the prescription of Chinese herbal medicine (CHM) and its benefits for the patients with gastric cancer in Taiwan.From the Registry for Catastrophic Illness Patients Database, we included all patients with gastric cancer whose age at diagnosis was ≥18 from 1997 to 2010 in T ...
- DOI:
- 10.1016/j.jep.2017.02.004
-
https://dx.doi.org/10.1016/j.jep.2017.02.004
- Author:
- Lin, Huang Q.; Gong, Amy G.W.; Wang, Huai Y.; Duan, Ran; Dong, Tina T.X.; Zhao, Kui J.; Tsim, Karl W.K.
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 205-210
- ISSN:
- 0378-8741
- Subject:
- Angelica sinensis; Oriental traditional medicine; herbs; human health; mechanism of action; menopause; proteomics; quality control; women
- Abstract:
- ... Traditional Chinese medicine (TCM) has contributed greatly to human health in past several thousand years. Today, the development of TCM is facing two obstacles: (i) quality control of herbal extract; and (ii) action mechanisms not known.Among thousands of complex TCM formulations, Danggui Buxue Tang (DBT) is the simplest one. DBT is used to treat ailments in women and contains only two herbs, Ast ...
- DOI:
- 10.1016/j.jep.2017.01.044
-
https://dx.doi.org/10.1016/j.jep.2017.01.044
- Author:
- Odoma, Saidi; Umar Zezi, Abdulkadir; Mohammed Danjuma, Nuhu; Ahmed, Abubakar; Garba Magaji, Muhammed
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 323-327
- ISSN:
- 0378-8741
- Subject:
- Yellow fever virus; acetic acid; analgesic effect; animals; arginine; butanol; fractionation; glibenclamide; leaf extracts; leaves; morphine; naloxone; neoplasms; oral administration; pain tests; propranolol; traditional medicine; yohimbine
- Abstract:
- ... Preparations of Olax subscorpioidea have been used traditionally for the management of pains, inflammatory diseases, yellow fever, cancer and rheumatism. Previously, the analgesic activity of its leaf extract have been reported. Furthermore, an analgesic assay guided fractionation showed that the butanol soluble fraction is the most active. However, the mechanism of this activity remains to be elu ...
- DOI:
- 10.1016/j.jep.2016.12.052
-
https://dx.doi.org/10.1016/j.jep.2016.12.052
- Author:
- Sadat-Hosseini, Mohammad; Farajpour, Mostafa; Boroomand, Naser; Solaimani-Sardou, Farshad
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 194-204
- ISSN:
- 0378-8741
- Subject:
- Apiaceae; Asteraceae; Calotropis procera; Genista tinctoria; Lamiaceae; Prunus eburnea; Prunus mahaleb; aerial parts; fever; indigenous peoples; leaves; medicinal plants; quantitative analysis; traditional medicine; Iran
- Abstract:
- ... The aim of this study was to collect and document information concerning the medicinal plants used by indigenous people and traditional healers in the south of Kerman Province, Iran.Overall, 64 informants between the ages of 30 and 89 were interviewed about the modes of application and consumption of medicinal plants in the region. Quantitative analysis was conducted that included informant consen ...
- DOI:
- 10.1016/j.jep.2017.02.006
-
https://dx.doi.org/10.1016/j.jep.2017.02.006
- Author:
- Uday, Priyanka; Maheshwari, M.; Sharanappa, P.; Nafeesa, Zohara; Kameshwar, Vivek Hamse; Priya, B.S.; Nanjunda Swamy, S.
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 316-322
- ISSN:
- 0378-8741
- Subject:
- Tabernaemontana; animal models; casein; coagulants; cysteine proteinases; edema; fibrin; fibrinogen; hemorrhage; hemostasis; histopathology; humans; hydrolysis; latex; mice; polymers; proteolysis; skin diseases; tissue repair; traditional medicine
- Abstract:
- ... The latex of Ervatamia heyneana (Wall.) T. Cooke plant has been used for wound healing and various skin diseases by Indian tribes and folklore.To validate the scientific basis of heynein – a key protease of Ervatamia heyneana, in hemostasis and wound healing process.The latex from E. heyneana was processed and subjected to two step purification. The purified heynein was assayed for proteolytic act ...
- DOI:
- 10.1016/j.jep.2016.12.047
-
https://dx.doi.org/10.1016/j.jep.2016.12.047
- Author:
- Zeng, Liuting; Yang, Kailin
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 68-85
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; active ingredients; bioavailability; breast neoplasms; drugs; genes; mechanism of action; permeability; pharmacology; prediction
- Abstract:
- ... Certain Chinese medicine formulae from traditional Chinese Medicine (TCM) are effective for treating and preventing diseases in clinical practice. Yanghe Decoction (YHD) is a Chinese medicine formula that is used to treat breast cancer, especially HER-positive breast cancer; however, the active compounds, potential targets, and pharmacological and molecular mechanism of its action against cancer r ...
- DOI:
- 10.1016/j.jep.2017.01.045
-
https://dx.doi.org/10.1016/j.jep.2017.01.045
- Author:
- Tao, Yi; Chen, Xi; Li, Weidong; Cai, Baochang; Di, Liuqing; Shi, Liyun; Hu, Lihong
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 20-29
- ISSN:
- 0378-8741
- Subject:
- Dipsacus; Oriental traditional medicine; amino acid metabolism; biomarkers; biomechanics; biosynthesis; blood serum; carbohydrate metabolism; chemistry; data collection; discriminant analysis; energy metabolism; estradiol; females; galactose; gas chromatography-mass spectrometry; genes; isoleucine; kidneys; least squares; leucine; liver; metabolites; metabolomics; methane; model validation; models; oral administration; osteoporosis; phenylalanine; principal component analysis; protective effect; rats; serine; sodium chloride; threonine; tryptophan; tyrosine; valine
- Abstract:
- ... Dipsacus asper Wall. ex C.B. Clarke (DA) is an effectively traditional Chinese medicine for treating osteoporosis and bone fracture. Until now, studies on pharmacological mechanism of DA mostly centered on cell and gene level, little is known about its metabolic signatures. The aim of this study is to investigate the anti-osteoporosis effects of crude and wine-processed DA by global and untargeted ...
- DOI:
- 10.1016/j.jep.2017.01.050
-
https://dx.doi.org/10.1016/j.jep.2017.01.050
- Author:
- Giovannini, Peter; Howes, Melanie-Jayne R.
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 240-256
- ISSN:
- 0378-8741
- Subject:
- Aristolochia; Cissampelos; Hamelia patens; Ipomoea; Passiflora; Peperomia; Piper; Sansevieria; Scoparia dulcis; Strychnos; anxiety; databases; medicinal plants; pain; people; rural areas; snake bites; traditional medicine; Belize; Costa Rica; El Salvador; Guatemala; Honduras; Nicaragua
- Abstract:
- ... Every year between 1.2 and 5.5 million people worldwide are victims of snakebites, with about 400,000 left permanently injured. In Central America an estimated 5500 snakebite cases are reported by health centres, but this is likely to be an underestimate due to unreported cases in rural regions. The aim of this study is to review the medicinal plants used traditionally to treat snakebites in seven ...
- DOI:
- 10.1016/j.jep.2017.02.011
-
https://dx.doi.org/10.1016/j.jep.2017.02.011
- Author:
- Li, Qing; Qu, Fa-Lin; Gao, Yue; Jiang, Yi-Ping; Rahman, Khalid; Lee, Kuo-Hsiung; Han, Ting; Qin, Lu-Ping
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 9-19
- ISSN:
- 0378-8741
- Subject:
- Piper; blood serum; corticosterone; ethyl acetate; herbal medicines; hippocampus; locomotion; mechanism of action; mice; mitogen-activated protein kinase; models; phosphorylation; protein synthesis; quantitative polymerase chain reaction; rats; reverse transcriptase polymerase chain reaction; signal transduction; sucrose; swimming; tail suspension test; traditional medicine
- Abstract:
- ... There are many plants of genus Piper which have been reported to induce antidepressant-like effects, Piper sarmentosum (PS) is one of them. PS is a Chinese herbal medicine and a traditional edible vegetable.In the present study, the antidepressant-like effects of PS extracts and the ethyl acetate fraction of PS extracts (PSY) were assessed using the open field test (OFT), forced swimming test (FST ...
- DOI:
- 10.1016/j.jep.2017.01.037
-
https://dx.doi.org/10.1016/j.jep.2017.01.037
- Author:
- Rahmati, Batool; Beik, Ahmad
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 39-51
- ISSN:
- 0378-8741
- Subject:
- Nepeta; blood; males; methadone; mice; morphine; naloxone; nitric oxide; pain; traditional medicine
- Abstract:
- ... Repeated administration of morphine for chronic pain leads to dependence and tolerance that limits clinical usage. Nepeta menthoides is commonly known as Iranian Ustukhuddoos and are administered in traditional medicine for gastrodynia, bone pain, blood depurative and restlessness.To investigate the effects of Nepeta menthoides on expression and acquisition of morphine dependence and tolerance in ...
- DOI:
- 10.1016/j.jep.2017.01.032
-
https://dx.doi.org/10.1016/j.jep.2017.01.032
- Author:
- Joseph, Litty; Aranjani, Jesil Mathew; Pai, K. Sreedhara Ranganath; Srinivasan, K.K.
- Source:
- Journal of ethnopharmacology 2017 v.199 pp. 231-239
- ISSN:
- 0378-8741
- Subject:
- Artemia; Justicia; angiogenesis; animal models; antineoplastic activity; bronchitis; chemical structure; cytotoxicity; growth retardation; in vitro studies; in vivo studies; inflammation; liquid chromatography; mass spectrometry; metastasis; mice; neoplasms; nuclear magnetic resonance spectroscopy; petroleum; prognosis; traditional medicine; vascular endothelial growth factors; India
- Abstract:
- ... Justicia simplex D. Don. belonging to the family of Acanthaceae has been traditionally used for treatment of rheumatism, inflammation and bronchitis. The plant is traditionally considered as an anticancer medicine and is used by healers of Karnataka to treat various types of cancers.The present study aims at the elucidation of anticancer activity of various extracts of J. simplex, isolation of its ...
- DOI:
- 10.1016/j.jep.2017.01.046
-
https://dx.doi.org/10.1016/j.jep.2017.01.046