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Journal of ethnopharmacology
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2016
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2016 v.187
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- Author:
- Geck, Matthias S.; Reyes García, Alberto J.; Casu, Laura; Leonti, Marco
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 146-159
- ISSN:
- 0378-8741
- Subject:
- acculturation; children; data collection; digestive system diseases; ethnobotany; flora; health services; medicinal plants; modernization; musculoskeletal system; respiratory tract diseases; rural areas; traditional medicine; women; Mexico
- Abstract:
- ... In rural areas of Mexico the impact of modernization has changed healthcare and health seeking behaviour to varying degrees. This has rarely been accounted for when discussing and comparing medicinal floras. The ethnomedical system of the Zoque has never before been systematically studied.The objective of this study was to document medical practices and medicinal plant knowledge of the Zoque of Ch ...
- DOI:
- 10.1016/j.jep.2016.04.036
- https://dx.doi.org/10.1016/j.jep.2016.04.036
- Author:
- Fan, Peng-Cheng; Ma, Hui-Ping; Hao, Ying; He, Xi-Rui; Sun, Ai-Jun; Jiang, Wei; Li, Mao-Xing; Jing, Lin-Lin; He, Lei; Ma, Jun; Jia, Zheng-Ping
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 232-238
- ISSN:
- 0378-8741
- Subject:
- blood platelets; prothrombin; u-plasminogen activator; traditional medicine; blood coagulation; lysine; hemostasis; models; coagulants; mice; kidneys; thrombin; thromboplastin; adverse effects; intravenous injection; fibrinogen; hemorrhage; fibrinolysis; iridoid glycosides; active ingredients
- Abstract:
- ... Fibrinolysis prevents blood clots from growing and becoming problematic. Antifibrinolytics are used as inhibitors of fibrinolysis. Aprotinin was doubted after identification of major side effects, especially on kidney. Lysine analogues has their own defects and whether they are adequate substitutes for aprotinin is still under doubt. Lamiophlomis rotata (Benth.) Kudo. was previous found to have he ...
- DOI:
- 10.1016/j.jep.2016.04.016
- https://dx.doi.org/10.1016/j.jep.2016.04.016
- Author:
- Lin, Yu-En; Lin, Shih-Hang; Chen, Wei-Cheng; Ho, Chi-Tang; Lai, Yi-Syuan; Panyod, Suraphan; Sheen, Lee-Yan
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 57-65
- ISSN:
- 0378-8741
- Subject:
- Gastrodia elata; Western blotting; abnormal behavior; amine oxidase (flavin-containing); animal models; blood serum; body weight; corticosterone; dopamine; forced swimming test; herbal medicines; nervous system diseases; neurotransmitters; oral administration; protein synthesis; rats; serotonin; sucrose; traditional medicine; tyrosine 3-monooxygenase
- Abstract:
- ... Gastrodia elata Blume (GE) is a traditional herbal medicine belonging to the Orchidaceae family, and has been used to manage neurological disorders for centuries. We have previously reported that its water extract (WGE) could improve the depressive-like behaviours in the forced swimming test (FST), an animal model of depression.To investigate the antidepressant-like effects of WGE in rats exposed ...
- DOI:
- 10.1016/j.jep.2016.04.032
- https://dx.doi.org/10.1016/j.jep.2016.04.032
- Author:
- Boakye, Yaw Duah; Agyare, Christian; Abotsi, Wonder Kofi Mensah; Ayande, Patrick George; Ossei, Paul Poku Sampene
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 17-27
- ISSN:
- 0378-8741
- Subject:
- Euphorbiaceae; Phyllanthus; adjuvants; anti-inflammatory activity; arthritis; edema; ethnobotany; hindlimbs; histology; inflammation; leaf extracts; models; pain; radiography; rats; shrubs; traditional medicine; Western Africa
- Abstract:
- ... Phyllanthus muellerianus (Kuntze) Exell. which belongs to the Family Euphorbiaceae is a shrub widely distributed in West Africa. It is used traditionally to manage wounds and wound infections, menstrual disorders, fevers, pain and inflammation. Hence to confirm its ethnobotanical uses in managing inflammation, we investigated the anti-inflammatory properties of aqueous leaf extract of P. muelleria ...
- DOI:
- 10.1016/j.jep.2016.04.020
- https://dx.doi.org/10.1016/j.jep.2016.04.020
5. Anti-inflammatory and anti-arthritic effects of taraxasterol on adjuvant-induced arthritis in rats
- Author:
- Wang, Shasha; Wang, Ying; Liu, Xinyu; Guan, Lizeng; Yu, Longzheng; Zhang, Xuemei
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 42-48
- ISSN:
- 0378-8741
- Subject:
- Taraxacum; adjuvants; arthritis; blood serum; body weight changes; cartilage; enzyme-linked immunosorbent assay; eosin; histopathology; hyperplasia; immunization; interleukin-1beta; medicinal plants; protective effect; rats; spleen; thymus gland; traditional medicine; tumor necrosis factor-alpha
- Abstract:
- ... Taraxasterol was isolated from the traditional Chinese medicinal herb Taraxacum which has been frequently used as a remedy for inflammatory diseases. In the present study, we determined the in vivo anti-arthritic effect of taraxasterol on arthritis induced by Freund's complete adjuvant (FCA) in rats.Rats were immunized with FCA by intradermal injection into the right hind metatarsal footpad, and w ...
- DOI:
- 10.1016/j.jep.2016.04.031
- https://dx.doi.org/10.1016/j.jep.2016.04.031
- Author:
- Gutiérrez-Rebolledo, Gabriel Alfonso; Garduño-Siciliano, Leticia; García-Rodríguez, Rosa Virginia; Pérez-González, Mariana Zuleima; Chávez, María Isabel; Bah, Moustapha; Siordia-Reyes, Georgina Alicia; Chamorro-Cevallos, Germán Alberto; Jiménez-Arellanes, María Adelina
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 269-280
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; adverse effects; aerial parts; anti-inflammatory activity; antioxidant activity; antioxidants; carrageenan; chemical constituents of plants; death; diarrhea; females; histology; influenza; inhibitory concentration 50; lethal dose 50; males; medicinal plants; metabolites; mice; models; nuclear magnetic resonance spectroscopy; subacute toxicity; thin layer chromatography; traditional medicine; ursolic acid; verbascoside
- Abstract:
- ... Moussonia deppeana, known as Tlachichinole, is a Mexican medicinal plant used for treatment of inflammatory diseases, influenza, diarrhea, gastrointestinal disorders and arthritis.In this paper the antioxidant and anti-inflammatory activities as well as the acute and sub-acute toxicological effects were evaluated for the ethanolic extract from aerial parts of M. deppeana, also its phytochemical an ...
- DOI:
- 10.1016/j.jep.2016.04.033
- https://dx.doi.org/10.1016/j.jep.2016.04.033
- Author:
- Cao, Yuan; Wang, Jing; Su, Guozhu; Wu, Yan; Bai, Ruifeng; Zhang, Qian; Gao, Xiaoli; Li, Chun; Chen, Suyile; Tu, Pengfei; Chai, Xingyun
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 259-268
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Syringa; Western blotting; aspirin; blood serum; cardiac output; collagen; coronary vessels; creatine kinase; dose response; echocardiography; ethanol; fluorescent antibody technique; heart; high performance liquid chromatography; infarction; lactate dehydrogenase; males; mice; models; myocardial ischemia; prostaglandin synthase; protective effect; tissues; China
- Abstract:
- ... The peeled stem of Syringa pinnatifolia Hemsl. (SP) is a traditional medicine in Inner Mongolia, China. The powder form of SP has been widely used for hundreds of years to relieve “He-Yi” related myocardial ischemia independently or in a traditional Chinese medicine preparation.SP was extracted with 95% and 80% ethanol. Chemical profiling was performed using HPLC-DAD and IT-TOF-ESI-MS analyses. My ...
- DOI:
- 10.1016/j.jep.2016.04.039
- https://dx.doi.org/10.1016/j.jep.2016.04.039
- Author:
- Wandji, Bibiane Aimée; Tatsinkou Bomba, Francis Desire; Awouafack, Maurice Ducret; Nkeng-Efouet, Pepin Alango; Kamanyi, Albert; Nguelefack, Télesphore Benoît
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 224-231
- ISSN:
- 0378-8741
- Subject:
- Artemia salina; Pittosporum; acetic acid; analgesic effect; antagonists; atropine; capsaicin; chemical constituents of plants; cytotoxicity; formalin; larvae; leaves; lethal concentration 50; liquid chromatography; maceration; mass spectrometry; mechanism of action; methanol; mice; naloxone; narcotics; oral administration; pain; receptors; traditional medicine; yohimbine; Africa
- Abstract:
- ... Pittosporum mannii (Pittosporaceae) is used in Africa traditional medicine to treat various ailments including pain and inflammation.The present work was undertaken to evaluate the antinociceptive effects of the aqueous (AEPM) and methanol (MEPM) extracts from the leaves of Pittosporum mannii.High performance liquid chromatography coupled with mass spectrometry (LCMS) was used for the phytochemica ...
- DOI:
- 10.1016/j.jep.2016.04.041
- https://dx.doi.org/10.1016/j.jep.2016.04.041
- Author:
- Barboza, Lorena Neris; Lívero, Francislaine Aparecida dos Reis; Prando, Thiago Bruno Lima; Ribeiro, Rita de Cassia Lima; Lourenço, Emerson Luiz Botelho; Budel, Jane Manfron; de Souza, Lauro Mera; Acco, Alexandra; Dalsenter, Paulo Roberto; Gasparotto, Arquimedes
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 134-145
- ISSN:
- 0378-8741
- Subject:
- Cuphea carthagenensis; New Zealand White rabbit; animal feeding; antioxidant activity; antioxidants; aorta; atherogenesis; atherosclerosis; blood lipids; blood serum; body weight; catalase; cholesterol; diet; ethanol; euthanasia; glutathione; hyperlipidemia; lipid peroxidation; models; nitrites; oral administration; oxidative stress; rabbits; superoxide dismutase; traditional medicine; triacylglycerols; New Zealand
- Abstract:
- ... Although Cuphea carthagenensis (Jacq.) J. F. Macbr. is used in Brazilian folk medicine in the treatment of atherosclerosis and circulatory disorders, no study evaluating these effects has been conducted. The aim of this study was to evaluate the possible hypolipemiant and antiatherogenic activity of the ethanol soluble fraction obtained from C. carthagenensis (ES-CC) in an experimental atheroscler ...
- DOI:
- 10.1016/j.jep.2016.04.027
- https://dx.doi.org/10.1016/j.jep.2016.04.027
- Author:
- Lumpert, Mateja; Kreft, Samo
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 1-8
- ISSN:
- 0378-8741
- Subject:
- Amanita muscaria; Diptera; farmers; farms; heat; high performance liquid chromatography; hills; hygiene; interviews; milk; mushrooms; pesticides; recipes; soaking; solvents; traditional medicine; villages; Slovenia
- Abstract:
- ... Fly control is necessary for maintaining good hygiene on farms. Because organic farmers are skeptical about chemical pesticides, alternative fly control remedies are being considered. Amanita muscaria is a widespread fungus that contains ibotenic acid and muscimol. This fungus has been used to catch flies for centuries, but traditional recipes are poorly described, documented and characterized.The ...
- DOI:
- 10.1016/j.jep.2016.04.009
- https://dx.doi.org/10.1016/j.jep.2016.04.009
- Author:
- Meng, Qiong; Yau, Lee-Fong; Lu, Jing-Guang; Wu, Zhen-Zhen; Zhang, Bao-Xian; Wang, Jing-Rong; Jiang, Zhi-Hong
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 74-82
- ISSN:
- 0378-8741
- Subject:
- antineoplastic activity; bufadienolides; cytotoxicity; neoplasms; quality control; toad venoms; toads; toxicity testing; traditional medicine
- Abstract:
- ... Toad venom and toad skin have been widely used for treating various cancers in China. Bufadienolides are regarded as the main anticancer components of toad venom, but the difference on composition and anticancer activities of bufadienolides between toad venom and toad skin remains unclear.Fractions enriched with free and conjugated bufadienolides were prepared from toad venom and toad skin. Bufadi ...
- DOI:
- 10.1016/j.jep.2016.03.062
- https://dx.doi.org/10.1016/j.jep.2016.03.062
- Author:
- Drobnik, Jacek
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 293-301
- ISSN:
- 0378-8741
- Subject:
- Acacia catechu; Achyranthes japonica; Akebia quinata; Angelica dahurica; Aquilaria sinensis; Aralia cordata; Aristolochia; Clematis vitalba; Coix lacryma-jobi; Commiphora myrrha; Cydonia oblonga; Daemonorops; Dictamnus dasycarpus; Dryobalanops aromatica; Europeans; Forsythia suspensa; Glycyrrhiza uralensis; Ligusticum; Lonicera confusa; Lonicera japonica; Oriental traditional medicine; Piper kadsura; Pseudocydonia sinensis; Pterocarpus officinalis; Saposhnikovia divaricata; Sassafras; Smilax china; Stephania tetrandra; Styphnolobium japonicum; Trichosanthes kirilowii; arsenic; homeopathic drugs; medicinal plants; mercury; plant anatomy; sexually transmitted diseases; surveys; China
- Abstract:
- ... Historical medical sources can be still queried for forgotten cures and remedies. Traditional Chinese medicine has dealt with lues venerea (syphilis) since the Five Dynasties period (10th century). Chinese indigenous materia medica and remedies recorded, studied or imported by the Europeans can reveal known or quite unknown medicinal plants. The studied Jean Astruc's work is a published ethnopharm ...
- DOI:
- 10.1016/j.jep.2016.04.055
- https://dx.doi.org/10.1016/j.jep.2016.04.055
- Author:
- Gu, Junfei; Chen, Juan; Yang, Nan; Hou, Xuefeng; Wang, Jing; Tan, Xiaobin; Feng, Liang; Jia, Xiaobin
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 313-324
- ISSN:
- 0378-8741
- Subject:
- 2,3,5-triphenyltetrazolium chloride; Ligusticum sinense; Western blotting; analytical kits; apoptosis; blood serum; blood-brain barrier; brain; catalase; endoplasmic reticulum; enzyme-linked immunosorbent assay; gene expression; gene expression regulation; glucose; glutathione peroxidase; immunohistochemistry; infarction; ischemia; messenger RNA; neurons; plasminogen activator; plasminogen activator inhibitors; protective effect; protein synthesis; quantitative polymerase chain reaction; rats; receptors; reverse transcriptase polymerase chain reaction; signal transduction; staining; superoxide dismutase; tissues; traditional medicine; vascular endothelial growth factors
- Abstract:
- ... Combination of Ligusticum chuanxiong and Radix Paeoniae (XS) is highly effective in the treatment for focal cerebral ischemic, but the underlying mechanism is not clear. This study was conducted to evaluate the combinative effects of XS on MCAO rats and explore the underlying mechanisms.MCAO rats were used to evaluate the protective effect of Ligusticum chuanxiong (CX), Radix Paeoniae Rubra (CS) a ...
- DOI:
- 10.1016/j.jep.2016.04.024
- https://dx.doi.org/10.1016/j.jep.2016.04.024
- Author:
- Ali-Shtayeh, Mohammed S.; Jamous, Rana M.; Salameh, Nihaya M.Y.; Jamous, Rania M.; Hamadeh, Amneh M.A.
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 104-122
- ISSN:
- 0378-8741
- Subject:
- Arum palaestinum; Ephedra; alternative medicine; antineoplastic agents; chronic diseases; databases; drug interactions; drug therapy; health care workers; herbal medicines; herbs; neoplasm cells; neoplasms; patients; pharmacokinetics; questionnaires; surveys; toxicity; traditional medicine; villages; Palestine
- Abstract:
- ... The use of CAM including herbal medicine as the most preferred CAM modality, among cancer patients who are taking prescription medications has shown to be highly prevalent worldwide as well as in several Middle Eastern countries, with a high percentage of the patients do not disclose their CAM use to treating physician.The current study aimed to evaluate the patterns of CAM use among two cohorts o ...
- DOI:
- 10.1016/j.jep.2016.04.038
- https://dx.doi.org/10.1016/j.jep.2016.04.038
- Author:
- Foo, Jhi Biau; Saiful Yazan, Latifah; Tor, Yin Sim; Wibowo, Agustono; Ismail, Norsharina; Armania, Nurdin; Cheah, Yoke Kqueen; Abdullah, Rasedee
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 195-204
- ISSN:
- 0378-8741
- Subject:
- Dillenia suffruticosa; Western blotting; alpha-tocopherol; antioxidants; apoptosis; ascorbic acid; betulinic acid; breast neoplasms; cell cycle checkpoints; cytotoxicity; flow cytometry; genes; light microscopes; medicinal plants; methylene chloride; mitochondria; mitogen-activated protein kinase; neoplasm cells; oxidative stress; proteins; signal transduction; solvents; traditional medicine; Malaysia
- Abstract:
- ... Dillenia suffruticosa is traditionally used for treatment of cancerous growth including breast cancer in Malaysia.Dillenia suffruticosa is a well-known medicinal plant in Malaysia for the treatment of cancer. Nevertheless, no study has been reported the cytotoxicity of this plant towards MDA-MB-231 triple-negative breast cancer cells. The present study was designed to investigate the mode of cell ...
- DOI:
- 10.1016/j.jep.2016.04.048
- https://dx.doi.org/10.1016/j.jep.2016.04.048
- Author:
- Sung, Yoon-Young; Lee, A Yeong; Kim, Ho Kyoung
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 49-56
- ISSN:
- 0378-8741
- Subject:
- interferon-gamma; high performance liquid chromatography; Dermatophagoides farinae; skin lesions; ears; methylene chloride; gene expression; traditional medicine; messenger RNA; blood serum; anti-allergic agents; mites; mice; immunoglobulin E; topical application; histamine; fruits; Forsythia suspensa; fruit extracts; inflammation; animal models; atopic dermatitis; mast cells; interleukin-4; matairesinol
- Abstract:
- ... Forsythia suspensa is used in traditional medicine to treat inflammation. To clarify the anti-inflammatory and anti-allergic effects of F. suspensa fruits, we determined the therapeutic effects of crude extract, fractions, and a constituent from F. suspensa fruits on a murine atopic dermatitis (AD) model.We investigated the inhibitory effects of F. suspensa extract (FSE), extract fractions, and th ...
- DOI:
- 10.1016/j.jep.2016.04.015
- https://dx.doi.org/10.1016/j.jep.2016.04.015
- Author:
- Sun, Jiahong; Ren, Xuefang; Qi, Wen; Yuan, Dan; Simpkins, James W.
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 249-258
- ISSN:
- 0378-8741
- Subject:
- NADP (coenzyme); Western blotting; adenosine triphosphate; cell lines; cell viability; cytotoxicity; energy; energy metabolism; glycolysis; hippocampus; methyl ethers; mitochondria; neurons; oxidative toxicity; protein content; reducing agents; staining; traditional medicine
- Abstract:
- ... The rate of production of reactive oxygen species (ROS) is determined by mitochondrial metabolic rate. In turn, excessive ROS damage mitochondrial function, which is linked to aging and neurodegenerative conditions. One possible path to prevent oxidative stress could be achieved by reducing mitochondrial respiration in favor of less efficient ATP production via glycolysis. Such a shift in energy m ...
- DOI:
- 10.1016/j.jep.2016.04.034
- PubMed:
- 27114061
- PubMed Central:
- PMC4887292
- https://dx.doi.org/10.1016/j.jep.2016.04.034
- Author:
- Lin, Xing; Wei, Jinbin; Chen, Yongxin; He, Ping; Lin, Jun; Tan, Shimei; Nie, Jinlan; Lu, Shengjuan; He, Min; Lu, Zhongpeng; Huang, Quanfang
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 187-194
- ISSN:
- 0378-8741
- Subject:
- Gypsophila elegans; active ingredients; antineoplastic activity; apoptosis; caspase-3; cell cycle checkpoints; cyclin-dependent kinase; cyclins; cytochrome c; cytosol; cytotoxicity; dose response; ethanol; flavonoids; genes; glycosides; herbal medicines; human cell lines; interphase; lactate dehydrogenase; liver neoplasms; membrane potential; mitochondrial membrane; neoplasm cells; proteolysis; reactive oxygen species; screening; traditional medicine; viability; China
- Abstract:
- ... Gypsophila elegans has been used as a traditional herbal medicine for treating immune disorders and chronic liver diseases in China. The aim of this study is to isolate an active ingredient from this herb and investigate its anti-tumor activity.An active ingredient was isolated from the ethanol extract using bioassay-guided screening. And its anti-tumor activity was analyzed by testing the cytotox ...
- DOI:
- 10.1016/j.jep.2016.04.050
- https://dx.doi.org/10.1016/j.jep.2016.04.050
- Author:
- He, Xirui; Bai, Yajun; Zhao, Zefeng; Wang, Xiaoxiao; Fang, Jiacheng; Huang, Linhong; Zeng, Min; Zhang, Qiang; Zhang, Yajun; Zheng, Xiaohui
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 160-182
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Styphnolobium japonicum; active ingredients; alkaloids; amino acids; antioxidants; branches; buds; databases; dysentery; flowers; fruits; glycemic effect; headache; hematuria; hemorrhage; hypertension; intestines; isoflavonoids; leaves; new drugs; pharmacology; polysaccharides; pyoderma; quality control; therapeutics; toxicity; toxicology; trees; triterpenoids; China; Japan; Korean Peninsula; Vietnam
- Abstract:
- ... Sophora japonica (Fabaceae), also known as Huai (Chinese: 槐), is a medium-sized deciduous tree commonly found in China, Japan, Korea, Vietnam, and other countries. The use of this plant has been recorded in classical medicinal treatises of ancient China, and it is currently recorded in both the Chinese Pharmacopoeia and European Pharmacopoeia. The flower buds and fruits of S. japonica, also known ...
- DOI:
- 10.1016/j.jep.2016.04.014
- https://dx.doi.org/10.1016/j.jep.2016.04.014
- Author:
- Pereira, Lívia de P.; Mota, Mario R.L.; Brizeno, Luiz A.C.; Nogueira, Francisca C.; Ferreira, Elda G.M.; Pereira, Maria G.; Assreuy, Ana M.S.
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 213-223
- ISSN:
- 0378-8741
- Subject:
- Caesalpinia ferrea; analgesics; analysis of variance; angiogenesis; collagen; enterocolitis; epithelium; granulation tissue; immunohistochemistry; interleukin-1beta; leukocytes; models; nitric oxide; permeability; protein content; rats; rheumatoid arthritis; tissue repair; traditional medicine; transforming growth factor beta; tumor necrosis factor-alpha
- Abstract:
- ... In folk medicine stem barks of Caesalpinia ferrea (Caesalpinioideae) are used to treat enterocolitis, rheumatism and wounds and in experimental procedures, its aqueous extracts demonstrated antiulcer, anti-inflammatory, analgesic, and healing effects.The healing mechanism of the polyssacharide-rich extract of C. ferrea stem barks (TPL-Cf) was investigated in a model of excisional cutaneous wound i ...
- DOI:
- 10.1016/j.jep.2016.04.043
- https://dx.doi.org/10.1016/j.jep.2016.04.043