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- Author:
- Kiraithe, Micheni N.; Nguta, Joseph M.; Mbaria, James M.; Kiama, Stephen G.
- Source:
- Journal of ethnopharmacology 2016 v.178 pp. 266-271
- ISSN:
- 0378-8741
- Subject:
- laboratory animals, etc ; Artemia; Ocimum gratissimum var. gratissimum; Plasmodium berghei; Plectranthus barbatus; Zanthoxylum; acute oral toxicity; albino; bioactive compounds; chloroform; chloroquine; death; fractionation; leaves; malaria; medicinal properties; methanol; mice; traditional medicine; Show all 19 Subjects
- Abstract:
- ... Crude extracts from the leaves of Ocimum suave Willd (Lamiaceae) and the root barks of Plectranthus barbatus Andrews (Lamiaceae) and Zanthoxylum chalybeum Engl. (Rutaceae) were studied to ascertain the ethnopharmacological standing of their antimalarial usage in Kenyan folk medicine.Aqueous and Chloroform: Methanol (1:1) extracts of the plants were used in this study. Toxicity of the extracts was ...
- DOI:
- 10.1016/j.jep.2015.12.013
-
https://dx.doi.org/10.1016/j.jep.2015.12.013
- Author:
- Wu, Hongzhong; Ren, Chunyan; Yang, Fang; Qin, Yufeng; Zhang, Yuanxing; Liu, Jianwen
- Source:
- Journal of ethnopharmacology 2016 v.182 pp. 129-136
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; cation exchange chromatography; peptides; hydrophobicity; hematopoietic stem cells; oral administration; anemia; dose response; neoplasms; blood sampling; bone marrow; patients; leukocyte count; irradiation; radiotherapy; females; reversed-phase liquid chromatography; sodium phosphate; hematopoiesis; body weight; acetonitrile; fluorouracil; mice; bioactive compounds; ionic strength; proteomics; monocytes; erythrocytes; tandem mass spectrometry; gamma radiation; Oriental traditional medicine; Show all 31 Subjects
- Abstract:
- ... Colla Corii Asini is a widely used traditional Chinese medicine to treat anemia with a long history due to its stimulating effect in hematopoiesis, but the components contributing to this effect are still unknown. In this study, we aimed to establish a methodology to isolate the bioactive components and provide pharmacological basis for its usage in treating anemia.5-FU and γ-ray radiation induced ...
- DOI:
- 10.1016/j.jep.2016.02.019
-
https://dx.doi.org/10.1016/j.jep.2016.02.019
- Author:
- Xu, Wei; Huang, Mingqing; Zhang, Yuqin; Li, Huang; Zheng, Haiyin; Yu, Lishuang; Chu, Kedan
- Source:
- Journal of ethnopharmacology 2016 v.185 pp. 140-146
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Bauhinia; IKappaB kinase; edema; ethyl acetate; gene expression regulation; in vitro studies; interleukins; messenger RNA; minorities (people); necrosis; neoplasms; rheumatoid arthritis; traditional medicine; transcription factor NF-kappa B; tumor necrosis factor-alpha; Show all 16 Subjects
- Abstract:
- ... Bauhinia championii (Benth.) Benth. is used in Chinese traditional medicine to treat arthritis, especially has been used a long time ago on rheumatoid arthritis (RA) in She ethnic minority group.To investigate the anti-RA effect of Bauhinia championii (Benth.) Benth ethyl acetate extract (BCBEE) and the molecular bases of it.BCBEE was studied on a rat model of RA induced by Ⅱcollagen in vivo, as w ...
- DOI:
- 10.1016/j.jep.2016.03.035
-
https://dx.doi.org/10.1016/j.jep.2016.03.035
- Author:
- Sung, Yoon-Young; Lee, A Yeong; Kim, Ho Kyoung
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 49-56
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; interferon-gamma; high performance liquid chromatography; Dermatophagoides farinae; skin lesions; ears; methylene chloride; gene expression; traditional medicine; messenger RNA; blood serum; anti-allergic agents; mites; mice; immunoglobulin E; topical application; histamine; fruits; Forsythia suspensa; fruit extracts; inflammation; atopic dermatitis; mast cells; interleukin-4; matairesinol; Show all 25 Subjects
- Abstract:
- ... Forsythia suspensa is used in traditional medicine to treat inflammation. To clarify the anti-inflammatory and anti-allergic effects of F. suspensa fruits, we determined the therapeutic effects of crude extract, fractions, and a constituent from F. suspensa fruits on a murine atopic dermatitis (AD) model.We investigated the inhibitory effects of F. suspensa extract (FSE), extract fractions, and th ...
- DOI:
- 10.1016/j.jep.2016.04.015
-
https://dx.doi.org/10.1016/j.jep.2016.04.015
- Author:
- Nascimento, André L.B.; Lozano, Alejandro; Melo, Joabe G.; Alves, Rômulo R.N.; Albuquerque, Ulysses Paulino
- Source:
- Journal of ethnopharmacology 2016 v.194 pp. 348-357
- ISSN:
- 0378-8741
- Subject:
- animals, etc ; data collection; interviews; medicinal plants; models; people; rural communities; semiarid zones; traditional medicine; Brazil; Show all 10 Subjects
- Abstract:
- ... This study sought to understand the role of plants and animals in traditional medical systems and evaluate the capacity of these systems to absorb impacts and maintain their identity by determining the existence of functional substitutes.Ethnobiological data were collected through semi-structured interviews and free lists at a rural community in the semiarid region of northeastern Brazil. The data ...
- DOI:
- 10.1016/j.jep.2016.08.017
-
https://dx.doi.org/10.1016/j.jep.2016.08.017
- Author:
- Liu, Na; Yang, Hua Li; Wang, Pu; Lu, Yu Cheng; Yang, Ying Juan; Wang, Lan; Lee, Shao Chin
- Source:
- Journal of ethnopharmacology 2016 v.189 pp. 210-217
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Annona muricata; Western blotting; apoptosis; bioinformatics; cell viability; endoplasmic reticulum; endoplasmic reticulum stress; ethanol; flow cytometry; human cell lines; leaves; liver neoplasms; neoplasm cells; protein content; proteins; proteomics; traditional medicine; Show all 18 Subjects
- Abstract:
- ... Annona muricata L. is used to treat cancer in some countries. Extracts of Annona muricata have been shown to cause apoptosis of various cancer cells in vitro, and inhibit tumor growth in vivo in animal models. However, the molecular mechanisms underlying its anti-cancer and apoptotic effects of the herb remain to be explored.The study investigated the molecular mechanisms underlying liver cancer c ...
- DOI:
- 10.1016/j.jep.2016.05.045
-
https://dx.doi.org/10.1016/j.jep.2016.05.045
- Author:
- Mohod, Smeeta M.; Kandhare, Amit D.; Bodhankar, Subhash L.
- Source:
- Journal of ethnopharmacology 2016 v.182 pp. 150-159
- ISSN:
- 0378-8741
- Subject:
- laboratory animals, etc ; Fourier transform infrared spectroscopy; Madhuca longifolia; acetic acid; analgesics; anti-ulcer activity; antioxidants; chloroform; flavones; histopathology; interleukin-1; leaves; liquid chromatography; males; mass spectrometry; molecular weight; nuclear magnetic resonance spectroscopy; prostaglandins; rats; spectral analysis; stomach; superoxide dismutase; traditional medicine; tumor necrosis factor-alpha; Show all 24 Subjects
- Abstract:
- ... Madhuca indica J. F. Gmel. (Sapotaceae) has shown antioxidant, anti-inflammatory, analgesic, anti-diabetic and hepatoprotective potential. It has been traditionally used as laxative, tonic, anti-burn, anti-earthworm, wound healing and headache.To investigate the efficacy and possible mechanism of Madhuca indica J. F. Gmel. leaves methanolic extract (MI-ALC) and its isolated chloroform fraction (D3 ...
- DOI:
- 10.1016/j.jep.2016.02.026
-
https://dx.doi.org/10.1016/j.jep.2016.02.026
- Author:
- Zhang, Yan; Pi, Zifeng; Song, Fengrui; Liu, Zhiqiang
- Source:
- Journal of ethnopharmacology 2016 v.194 pp. 188-195
- ISSN:
- 0378-8741
- Subject:
- animal behavior; animal models, etc ; Alzheimer disease; Panax ginseng; acetylcholine; aluminum chloride; amyloid; aspartic acid; cortex; crossing; dopamine; galactose; gamma-aminobutyric acid; ginsenosides; glutamic acid; herbal medicines; hippocampus; histopathology; immunohistochemistry; liquid chromatography; mass spectrometry; memory; neurotransmitters; rats; serotonin; staining; traditional medicine; Show all 27 Subjects
- Abstract:
- ... Panax ginseng C.A.Mey. is a traditional Chinese herbal medicine, which has been used to treat Alzheimer's disease (AD) for thousands of years. Ginsenoside is one of the major compounds found in P. ginseng. This study aimed to explore the attenuation of spatial memory impairment by ginsenosides and its correlation with restoring the dysfunction of the neurotransmitter systems in AD model rats to un ...
- DOI:
- 10.1016/j.jep.2016.09.007
-
https://dx.doi.org/10.1016/j.jep.2016.09.007
- Author:
- Choi, Sang-Pil; Choi, Chang-Yong; Park, Kyungmin; Kim, Nahyun; Moon, Hyun-Seuk; Lee, Dongho; Chun, Taehoon
- Source:
- Journal of ethnopharmacology 2016 v.178 pp. 13-16
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; B-lymphocytes; Dictamnus dasycarpus; T-lymphocytes; bark; herbal medicines; immunosuppression; interphase; lymphocyte proliferation; macrophages; mice; rheumatoid arthritis; splenocytes; therapeutics; traditional medicine; transcription factor NF-kappa B; triterpenoids; East Asia; Show all 18 Subjects
- Abstract:
- ... The root bark of Dictamnus dasycarpus Turcz. (Rutaceae) has been used as a traditional herbal medicine to treat various inflammatory diseases in East Asia. We have showed previously that a glabretal type triterpenoid (dictabretol A) from D. dasycarpus root bark has immunosuppressive activity.This study was conducted to define the molecular mechanism of how dictabretol A inhibits lymphocyte prolife ...
- DOI:
- 10.1016/j.jep.2015.10.043
-
https://dx.doi.org/10.1016/j.jep.2015.10.043
- Author:
- Lakshmanan, Hariprasath; Raman, Jegadeesh; David, Pamela; Wong, Kah-Hui; Naidu, Murali; Sabaratnam, Vikineswary
- Source:
- Journal of ethnopharmacology 2016 v.194 pp. 1051-1059
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Hericium; Oriental traditional medicine; adverse effects; antioxidants; behavior change; blood sampling; blood serum; body weight; electrolytes; fruiting bodies; heart; histopathology; ingestion; liver; morbidity; mortality; mushrooms; oral administration; rats; stomach; toxicity; toxicity testing; Show all 23 Subjects
- Abstract:
- ... Hericium erinaceus is a culinary-medicinal mushroom and has a long history of usage in traditional Chinese medicine as a tonic for stomach disorders, ulcers and gastrointestinal ailments.The present investigation was aimed to evaluate the potential toxic effects of the aqueous extract from the fruiting bodies of H. erinaceus in rats by a sub-chronic oral toxicity study.In this sub-chronic toxicity ...
- DOI:
- 10.1016/j.jep.2016.10.084
-
https://dx.doi.org/10.1016/j.jep.2016.10.084
- Author:
- Luo, Lan; Zhen, Lifeng; Xu, Yatao; Yang, Yongxia; Feng, Suxiang; Wang, Shumei; Liang, Shengwang
- Source:
- Journal of ethnopharmacology 2016 v.186 pp. 257-269
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Oriental traditional medicine; amino acid metabolism; biochemical pathways; brain; death; energy metabolism; histopathology; ischemia; metabolic diseases; metabolites; metabolomics; multivariate analysis; neuroprotective effect; nuclear magnetic resonance spectroscopy; oxidative stress; rats; staining; stroke; urine; Show all 20 Subjects
- Abstract:
- ... Stroke is a leading cause of death and disability in the world. However, current therapies are limited. Naodesheng, a widely used traditional Chinese medicine prescription, has shown a good clinical curative effect on ischemic stroke. Also, Naodesheng has been suggested to have neuroprotective effect on focal cerebral ischemia rats, but the underlying molecular mechanism remains unclear.The presen ...
- DOI:
- 10.1016/j.jep.2016.03.059
-
https://dx.doi.org/10.1016/j.jep.2016.03.059
- Author:
- Ge, Jing; Miao, Jun-Jun; Sun, Xin-Yi; Yu, Jiang-Yi
- Source:
- Journal of ethnopharmacology 2016 v.189 pp. 238-249
- ISSN:
- 0378-8741
- Subject:
- laboratory animals, etc ; Abelmoschus manihot; agonists; blood chemistry; blood serum; body weight; cholesterol; collagen; cultured cells; diabetic nephropathy; endoplasmic reticulum; endoplasmic reticulum stress; enzymes; inflammation; interleukin-6; intraperitoneal injection; kidneys; liver; males; medicinal plants; noninsulin-dependent diabetes mellitus; peroxisome proliferator-activated receptor alpha; peroxisome proliferator-activated receptor gamma; proteinuria; rats; reporter genes; streptozotocin; therapeutics; traditional medicine; transcription (genetics); transforming growth factor beta; triacylglycerols; tumor necrosis factor-alpha; Show all 33 Subjects
- Abstract:
- ... Abelmoschus manihot (L.) medic (AM) is a natural medicinal plant used for the treatment of chronic kidney disease (CKD) in China. Huangkui capsule (HKC), an extract from AM, has been proved clinically effective in improving renal inflammation and glomerular injury in CKD. However, the mechanisms of HKC are still not fully understood.Peroxisome proliferator–activated receptor (PPAR)-α/γ dual agonis ...
- DOI:
- 10.1016/j.jep.2016.05.033
-
https://dx.doi.org/10.1016/j.jep.2016.05.033
- Author:
- Li, Lei; Dong, Pengda; Hou, Congjia; Cao, Fangyuan; Sun, Shouli; He, Fa; Song, Yanping; Li, Sen; Bai, Yuhua; Zhu, Daling
- Source:
- Journal of ethnopharmacology 2016 v.186 pp. 224-233
- ISSN:
- 0378-8741
- Subject:
- animal models; laboratory animals, etc ; Carthamus tinctorius; adults; blood circulation; blood stasis; cell cycle; eosin; flowers; herbal medicines; hypertension; hypertrophy; hypoxia; immunohistochemistry; males; myocytes; proliferating cell nuclear antigen; pulmonary artery; quality control; rats; smooth muscle; staining; traditional medicine; China; Show all 24 Subjects
- Abstract:
- ... Carthamus tinctorius L. is a traditional herbal medicine native to China with properties of promoting blood circulation and removing blood stasis, which is used for the treatment of cerebrovascular and cardiovascular diseases. Hydroxysafflor yellow A (HSYA) is the main constituent isolated from the flower of Carthamus tinctorius L. which is used as a marker substance in the quality control of Cart ...
- DOI:
- 10.1016/j.jep.2016.04.004
-
https://dx.doi.org/10.1016/j.jep.2016.04.004
- Author:
- Cifuentes, Fredi; Paredes, Adrián; Palacios, Javier; Muñoz, Fernanda; Carvajal, Lorena; Nwokocha, Chukwuemeka R.; Morales, Glauco
- Source:
- Journal of ethnopharmacology 2016 v.179 pp. 367-374
- ISSN:
- 0378-8741
- Subject:
- animal disease models, etc ; Senecio; angiotensin II; antihypertensive effect; blood pressure; dose response; heart; heart rate; hypertension; indigenous species; mechanism of action; mice; muscles; oxygen; plants (botany); rats; therapeutics; traditional medicine; Andes region; South America; Show all 20 Subjects
- Abstract:
- ... Senecio nutans Sch. Bip. (Compositae) is an endemic plant of South America used in the management of acute mountain sickness in the Andean communities. Currently, the direct effects of hydroalcoholic extract from S. nutans on the cardiovascular system are unknown. The aim of this study was to determine the effects and mechanism of action of S. nutans on cardiovascular function in normotensive and ...
- DOI:
- 10.1016/j.jep.2015.12.048
-
https://dx.doi.org/10.1016/j.jep.2015.12.048
- Author:
- Rasheed, Hafiz Muhammad Farhan; Rasheed, Fahad; Qureshi, Abdul Wahid; Jabeen, Qaiser
- Source:
- Journal of ethnopharmacology 2016 v.186 pp. 244-250
- ISSN:
- 0378-8741
- Subject:
- laboratory animals, etc ; Leptadenia; adhesion; aerial parts; albino; antibodies; cough; delayed hypersensitivity; diabetes; disease control; dose response; erythrocytes; evaporation; fever; flora; hemagglutination; hematologic tests; immunostimulants; infectious diseases; kidneys; maceration; neutrophils; nylon; pellets; phagocytosis; rats; rhinitis; sheep; shrubs; stomach; traditional medicine; Pakistan; Show all 32 Subjects
- Abstract:
- ... Leptadenia pyrotechnica (Forssk.) Decne (Asclepiadaceae) is a well-renowned medicinal shrub, used by herbal practitioners for various ailments including allergic rhinitis, productive cough, abortion, diabetes, stomach disorders, fever, kidney disorders, stones and cancerOn the basis of folkloric uses, L. pyrotechnica was selected from the wide medicinal flora of the Cholistan desert of Pakistan, f ...
- DOI:
- 10.1016/j.jep.2016.03.039
-
https://dx.doi.org/10.1016/j.jep.2016.03.039
- Author:
- Lee, Hye Ji; Kim, Mi Hye; Choi, You Yeon; Kim, Eun Hye; Hong, Jongki; Kim, Kyuseok; Yang, Woong Mo
- Source:
- Journal of ethnopharmacology 2016 v.180 pp. 12-17
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Spirodela polyrhiza; Western blotting; atopic dermatitis; blood serum; dermis; eosin; histology; hyperplasia; immunoglobulin E; inflammation; interleukin-6; mast cells; mice; mitogen-activated protein kinase; nephritis; secretion; skin lesions; staining; toluidine blue; topical application; traditional medicine; transcription factor NF-kappa B; tumor necrosis factor-alpha; Show all 24 Subjects
- Abstract:
- ... Spirodela polyrhiza has been used as a traditional remedy for the treatment of urticarial, acute nephritis, inflammation, as well as skin disease.Atopic dermatitis (AD) is characterized hyperplasia of skin lesion and increase of serum immunoglobulin E (IgE) level. In this study, the topical effects of S. polyrhiza (SP) on 2, 4-dinitrochlorobenzene (DNCB)-induced AD mice model were investigated by ...
- DOI:
- 10.1016/j.jep.2016.01.010
-
https://dx.doi.org/10.1016/j.jep.2016.01.010
- Author:
- Zhang, Bei; Zhang, Rong-weng; Yin, Xi-quan; Lao, Zi-zhao; Zhang, Zhe; Wu, Qing-guang; Yu, Liang-wen; Lai, Xiao-ping; Wan, Yu-hua; Li, Geng
- Source:
- Journal of ethnopharmacology 2016 v.177 pp. 1-9
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Cynomorium songaricum; Ganoderma lucidum; Oriental traditional medicine; Platycladus orientalis; Polygonum; alopecia; blood serum; color; dihydrotestosterone; enzyme-linked immunosorbent assay; enzymes; epididymis; estradiol; ethanol; fluorescent antibody technique; hair follicles; herbal medicines; herbs; histology; hormone antagonists; leaves; maceration; metabolism; mice; morphogenesis; pharmacodynamics; rats; screening; testosterone; Show all 30 Subjects
- Abstract:
- ... Many traditional Chinese medicines (TCM) have been used for hundreds of years for hair blackening and hair nourishing, and now many of them are commonly used in Chinese herbal shampoo to nourish the hair and promote hair growth.The present study was performed to screen 5α-reductase (5αR) inhibitors from traditional Chinese medicines, evaluate its hair growth promoting activity in vivo, and further ...
- DOI:
- 10.1016/j.jep.2015.11.012
-
https://dx.doi.org/10.1016/j.jep.2015.11.012
- Author:
- Han, Xiaoli; Su, Dan; Xian, Xiaoyan; Zhou, Mingyang; Li, Xianzhe; Huang, Jian; Wang, Jinhui; Gao, Huiyuan
- Source:
- Journal of ethnopharmacology 2016 v.194 pp. 228-235
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Saussurea involucrata; adjuvants; endangered species; altitude; oral administration; body weight changes; alcohols; aspirin; enzyme-linked immunosorbent assay; traditional medicine; blood serum; humans; tumor necrosis factor-alpha; aerial parts; rats; interleukin-1beta; histopathology; rheumatoid arthritis; interleukin-6; Show all 20 Subjects
- Abstract:
- ... Saussurea involucrate (Kar. et Kir.) Sch. -Bip is an endangered species of the Compositae family, and this species has long been used for the treatment of rheumatoid arthritis, dysmenorrhea, stomachache, and altitude sickness in Uighur folk and Chinese medicine.This study aimed to investigate the different therapeutic efficacy of alcohol infusion (SEI) and water decoction (SWD) of S. involucrata i ...
- DOI:
- 10.1016/j.jep.2016.09.008
-
https://dx.doi.org/10.1016/j.jep.2016.09.008
- Author:
- Choi, Ki-Choon; Cho, Seong-Wan; Kook, Sung-Ho; Chun, Sa-Ra; Bhattarai, Govinda; Poudel, Sher Bahadur; Kim, Min-Kook; Lee, Kyung-Yeol; Lee, Jeong-Chae
- Source:
- Journal of ethnopharmacology 2016 v.179 pp. 55-65
- ISSN:
- 0378-8741
- Subject:
- animal models, etc ; Raphanus sativus; anti-inflammatory activity; antioxidants; chemokine CCL2; colitis; colon; glutathione; histology; intercellular adhesion molecule-1; interleukin-1beta; males; malondialdehyde; myeloperoxidase; nitric oxide; oxidative stress; rats; secretion; seeds; sinapic acid; traditional medicine; tumor necrosis factor-alpha; Show all 22 Subjects
- Abstract:
- ... Water extract of Raphanus sativus L. (RSL) seeds was traditionally used to treat digestive inflammatory complaints in Korean culture. RSL seeds exerted antioxidant, anti-inflammatory, and anti-septic functions, suggesting their pharmacological potential for the treatment of inflammatory pathologies associated with oxidative stress such as inflammatory bowel disease.We evaluated the intestinal anti ...
- DOI:
- 10.1016/j.jep.2015.12.045
-
https://dx.doi.org/10.1016/j.jep.2015.12.045
- Author:
- Sheikh, Yunus; Maibam, Beebina Chanu; Talukdar, Narayan Chandra; Deka, Dibakar Chandra; Borah, Jagat Chandra
- Source:
- Journal of ethnopharmacology 2016 v.191 pp. 21-28
- ISSN:
- 0378-8741
- Subject:
- animal disease models, etc ; Parkia timoriana; alpha-amylase; alpha-glucosidase; blood glucose; blood serum; diabetes; dietary supplements; epigallocatechin; glycemic effect; hepatoprotective effect; hypertension; inhibitory concentration 50; liver function; medicinal plants; pods; quantitative analysis; rats; streptozotocin; traditional medicine; uric acid; urinary tract diseases; Show all 22 Subjects
- Abstract:
- ... Parkia roxburghii G. Don. is a traditional medicinal plant and its pods are extensively used as food and medicine. It is believed by the traditional healers to have medicinal properties to treat diabetes, hypertension and urinary tract infections (Jamaluddin et al., 1994).The methanolic extract of pods of P roxburghii and fractions were screened for their α-glucosidase and α-amylase inhibitory act ...
- DOI:
- 10.1016/j.jep.2016.06.015
-
https://dx.doi.org/10.1016/j.jep.2016.06.015