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Journal of ethnopharmacology
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7985-2015
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2015 v.166
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- Author:
- Jingjing Wei; Limei Yao; Lei Yang; Wei Zhao; Si Shi; Qingyan Cai; Dingsheng Chen; Weirong Li; Qi Wang
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 333-339
- ISSN:
- 0378-8741
- Subject:
- Food and Drug Administration; Oriental traditional medicine; ethanol; fluorescence; gamma-aminobutyric acid; gene expression; high performance liquid chromatography; intraperitoneal injection; males; mechanism of action; messenger RNA; microdialysis; models; neurotransmitters; poisoning; rats; receptors; reverse transcriptase polymerase chain reaction; stroke; China
- Abstract:
- ... Xingnaojing Injection (XNJI) is a modern Chinese formula came from famous Chinese medicine An Gong Niu Huang Pill. XNJI has been used for treatment of cerebral diseases and stroke in China, and is approved by the State Food and Drug Administration of China for the treatment of acute alcohol intoxication (AAI). XNJI belongs to the ethnopharmacological family of medicines. In this study, we investig ...
- DOI:
- 10.1016/j.jep.2015.03.038
- https://doi.org/10.1016/j.jep.2015.03.038
- Author:
- H.O.B. Oloyede; T.O. Bello; T.O. Ajiboye; M.O. Salawu
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 313-322
- ISSN:
- 0378-8741
- Subject:
- Dioscoreophyllum cumminsii; animal disease models; blood glucose; blood serum; body weight; catalase; diabetes; dose response; glibenclamide; glucose 6-phosphate; glutathione peroxidase; glutathione-disulfide reductase; glycemic effect; high density lipoprotein cholesterol; hyperlipidemia; insulin; leaf extracts; leaves; liver; low density lipoprotein cholesterol; malondialdehyde; oxidative stress; pancreas; rats; superoxide dismutase; traditional medicine; triacylglycerols; Nigeria
- Abstract:
- ... Dioscoreophyllum cumminsii (Stapf) Diels leaves are used in the management of diabetics in Nigeria. Thus, the antidiabetic activity of aqueous D. cumminsii leaf extract and its capability to halt oxidative stress and dyslipidemia in alloxan-induced diabetic rats was investigated.Antidiabetic was evaluated in alloxan-induced diabetes rats. Diabetic rats were treated with 50, 100 and 200mg/kg body w ...
- DOI:
- 10.1016/j.jep.2015.02.049
- https://doi.org/10.1016/j.jep.2015.02.049
- Author:
- Yonglan Ma; Cuihua Jiang; Nan Yao; Yue Li; Qingqing Wang; Shengzuo Fang; Xulan Shang; Ming Zhao; Chuntao Che; Yicheng Ni; Jian Zhang; Zhiqi Yin
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 286-296
- ISSN:
- 0378-8741
- Subject:
- Cyclocarya paliurus; Western blotting; antioxidants; blood serum; diabetes; ethanol; glutathione peroxidase; high density lipoprotein cholesterol; high fat diet; hyperlipidemia; indigenous species; kidneys; leaves; liver; low density lipoprotein cholesterol; malondialdehyde; mice; mitogen-activated protein kinase; obesity; phosphorylation; quantitative polymerase chain reaction; renal function; reverse transcriptase polymerase chain reaction; staining; superoxide dismutase; traditional medicine; trees; triacylglycerols; tumor necrosis factor-alpha; China
- Abstract:
- ... Cyclocarya paliurus (CP) Batal., the sole species in its genus, is a native plant to China. As a traditional Chinese folk medicine, the tree leaves have been widely used for the treatment of metabolic disorders, including hyperlipidemia, obesity, diabetes and hypertension.The study aimed to evaluate the antihyperlipidemic effect of CP ethanol extract, as well as its inhibitory activity on apolipop ...
- DOI:
- 10.1016/j.jep.2015.03.030
- https://doi.org/10.1016/j.jep.2015.03.030
- Author:
- Emeline Houël; Marie Fleury; Guillaume Odonne; Flore Nardella; Geneviève Bourdy; Catherine Vonthron-Sénécheau; Pascal Villa; Adeline Obrecht; Véronique Eparvier; Eric Deharo; Didier Stien
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 279-285
- ISSN:
- 0378-8741
- Subject:
- American Indians; Plasmodium falciparum; Psidium acutangulum; aerial parts; anti-inflammatory activity; antioxidants; antiplasmodial properties; bioassays; chloroquine; cytotoxicity; dose response; inhibitory concentration 50; interleukin-1beta; interleukin-6; interleukin-8; macrophages; malaria; medicinal plants; mice; models; mononuclear leukocytes; nitric oxide; parasites; qualitative analysis; secretion; traditional medicine; trees; tritium; tumor necrosis factor-alpha; French Guiana
- Abstract:
- ... Field investigations highlighted the use of Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh), a small tree used by the Wayana Amerindians in Twenke–Taluhwen and Antecume–Pata, French Guiana, for the treatment of malaria, and administered either orally in the form of a decoction or applied externally over the whole body. This use appears limited to the Wayana cultural group in French Gui ...
- DOI:
- 10.1016/j.jep.2015.03.015
- https://doi.org/10.1016/j.jep.2015.03.015
- Author:
- Gang Chen; Yang Yang; Moli Liu; Zhiying Teng; Juan Ye; Yuehua Xu; Xueting Cai; Xiaolan Cheng; Jie Yang; Chunping Hu; Min Wang; Peng Cao
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 149-156
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Western blotting; body weight; colitis; dextran sulfate; diarrhea; drinking water; enzyme-linked immunosorbent assay; gastroenteritis; histology; interleukin-10; interleukin-17; interleukin-1beta; interleukin-23; interleukin-4; males; mice; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; superoxide dismutase; therapeutics; tissues; tumor necrosis factor-alpha
- Abstract:
- ... Banxia Xiexin decoction (BXD), one of a traditional Chinese medicine chronicled in Shang Han Lun, is commonly used to treat gastroenteritis, ulcerative colitis and diarrhea. In our study, we used current biomedical approaches to investigate the therapeutic efficacy of BXD and possible protective mechanism involved in inhibiting dextran sulfate sodium (DSS)-induced chronic ulcerative colitis model. ...
- DOI:
- 10.1016/j.jep.2015.03.027
- https://doi.org/10.1016/j.jep.2015.03.027
- Author:
- Nouhoum Diarra; Charlotte van’t Klooster; Adiaratou Togola; Drissa Diallo; Merlin Willcox; Joop de Jong
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 352-360
- ISSN:
- 0378-8741
- Subject:
- Anogeissus leiocarpa; Cassia; Cochlospermum; Culicidae; Entada; Guiera senegalensis; Mitragyna; Sarcocephalus latifolius; Trichilia emetica; antimalarials; chemical constituents of plants; children; cost effectiveness; death; ethnobotany; food security; interviews; malaria; medicinal plants; pregnant women; questionnaires; surveys; traditional medicine; villages; Mali
- Abstract:
- ... Plants have contributed to food security and disease treatments to rural populations in sub Saharan Africa for many centuries. These plants occupy a significant place in the treatment of diseases, such as malaria. In Mali, malaria is the leading cause of medical consultation and death. This infection is particularly dangerous for pregnant women and children under 5 years. The general aim of this r ...
- DOI:
- 10.1016/j.jep.2015.02.054
- https://doi.org/10.1016/j.jep.2015.02.054
- Author:
- Prakash Roy Choudhury; Manabendra Dutta Choudhury; Sanjoy Singh Ningthoujam; Dipan Das; Deepa Nath; Anupam Das Talukdar
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 135-148
- ISSN:
- 0378-8741
- Subject:
- Catharanthus roseus; Justicia adhatoda; chemical constituents of plants; counseling; digestive system diseases; herbal medicines; indigenous knowledge; leaves; medicinal plants; questionnaires; respiratory tract diseases; surveys; therapeutics; traditional medicine; India
- Abstract:
- ... Information about ethnomedicinal plants used by traditional healers in Tripura, India is very much limited. As there is rapid erosion of traditional knowledge in the state, needs has arisen to document the diversity of medicinal plants, their preparation and associated diseases.Attempts have been made to explore the herbal medicines used by the traditional healers belonging to the various communit ...
- DOI:
- 10.1016/j.jep.2015.03.026
- https://doi.org/10.1016/j.jep.2015.03.026
- Author:
- Sikiru Olaitan Balogun; Amilcar Sabino Damazo; Domingos Tabajara de Oliveira Martins
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 176-184
- ISSN:
- 0378-8741
- Subject:
- Helicteres; acidity; antagonists; antioxidants; catalase; enzyme activity; ethanol; gastric juice; glibenclamide; indomethacin; inflammation; laboratory animals; leaves; maceration; mechanism of action; mice; models; mucus; myeloperoxidase; pylorus; rats; secretion; stomach ulcers; traditional medicine; yohimbine; Brazil
- Abstract:
- ... Helicteres sacarolha A. St.- Hil. et al. popularly known in Brazil as ‘semente-de-macaco’, is widely employed in the popular medicine in many of parts of Brazil in the alleviation of symptoms of ailments such as peptic ulcer and inflammation. Up to the present, there is no study addressing the gastroprotective activity of the hydroethanolic extract of H. sacarolha and its possible mechanism of act ...
- DOI:
- 10.1016/j.jep.2015.03.021
- https://doi.org/10.1016/j.jep.2015.03.021
- Author:
- Shamika Ranasinghe; Rashid Ansumana; Joseph M. Lamin; Alfred S. Bockarie; Umaru Bangura; Jacob A.G. Buanie; David A. Stenger; Kathryn H. Jacobsen
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 200-204
- ISSN:
- 0378-8741
- Subject:
- Cassia; Morinda; Moringa oleifera; Sarcocephalus latifolius; Senna siamea; Uvaria; adults; antimalarials; herbs; malaria; phytotherapy; traditional medicine; Sierra Leone
- Abstract:
- ... Most adults in West Africa treat acute febrile illnesses with local herbs, but the patterns of herbs used for malaria have not been recently described in Sierra Leone.We used a population-based cross-sectional approach to interview 810 randomly-sampled rural and urban adult residents of Bo, Sierra Leone, in December 2013 and January 2014 about their use of herbal remedies when they suspect they ha ...
- DOI:
- 10.1016/j.jep.2015.03.028
- https://doi.org/10.1016/j.jep.2015.03.028
- Author:
- Hassan Sher; Ali Aldosari; Ahmad Ali; Hugo J. de Boer
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 157-167
- ISSN:
- 0378-8741
- Subject:
- Avena sativa; Celtis australis; Cynodon dactylon; Datura stramonium; Ficus palmata; Lathyrus; Plantago lanceolata; Rumex; Skimmia laureola; Solanum nigrum; Spiraea; Ziziphus jujuba; education; focus groups; forests; gender; health services; herbs; indigenous knowledge; marketing; medicinal plants; men; questionnaires; surveys; traditional medicine; women; Pakistan
- Abstract:
- ... Mapping ethnomedicinal plants and associated indigenous knowledge of folk medicines can provide a comprehensive overview of individual herbs employed in health care. Reliance on medicinal plants in remote parts of northern Pakistan is high, especially among women, but no research has investigated specifically which plants are used. This study investigated indigenous knowledge of folk medicines amo ...
- DOI:
- 10.1016/j.jep.2015.03.022
- https://doi.org/10.1016/j.jep.2015.03.022
- Author:
- Jhi Biau Foo; Latifah Saiful Yazan; Yin Sim Tor; Agustono Wibowo; Norsharina Ismail; Chee Wun How; Nurdin Armania; Su Peng Loh; Intan Safinar Ismail; Yoke Kqueen Cheah; Rasedee Abdullah
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 270-278
- ISSN:
- 0378-8741
- Subject:
- Dillenia suffruticosa; Western blotting; apoptosis; betulinic acid; bioactive compounds; breast neoplasms; breasts; caspase-3; cell cycle checkpoints; cytotoxicity; gene expression; genes; high performance liquid chromatography; interphase; messenger RNA; methylene chloride; mitochondria; neoplasm cells; nuclear magnetic resonance spectroscopy; post-translational modification; protein content; roots; signal transduction; solvents; traditional medicine; Malaysia
- Abstract:
- ... Dillenia suffruticosa (Family: Dilleniaceae) or commonly known as “Simpoh air” in Malaysia, is traditionally used for treatment of cancerous growth including breast cancer.D. suffruticosa root dichloromethane extract (DCM-DS) has been reported to induce G0/G1 phase cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 breast cancer cells. The present study was designed to investigate the in ...
- DOI:
- 10.1016/j.jep.2015.03.039
- https://doi.org/10.1016/j.jep.2015.03.039
- Author:
- Yinghao Wang; Shuisheng Wu; Zhichun Chen; Hua Zhang; Wanli Zhao
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 66-73
- ISSN:
- 0378-8741
- Subject:
- Gelsemium; arthritis; catalytic activity; chemical composition; coumarin; cytochrome P-450; enzyme activity; enzyme inhibition; enzymes; ethyl acetate; indole alkaloids; inhibitory concentration 50; methylene chloride; neoplasms; pain; petroleum; poisonous plants; psoriasis; roots; testosterone; traditional medicine; South East Asia
- Abstract:
- ... Gelsemium elegans (GE), widely distributed in East Asia, South East Asia and Northern America, is a kind of well-known toxic plant throughout the world. Yet it has been used as a Chinese folk medicine for treatment of malignant tumors, pain, rheumatic arthritis, psoriasis and immune function.The present study was to investigate the potential inhibitory effects of G. elegans (GE) roots on four majo ...
- DOI:
- 10.1016/j.jep.2015.03.002
- https://doi.org/10.1016/j.jep.2015.03.002
- Author:
- Tie Zhao; Haojun Zhang; Xianglin Zhang; Tingting Zhao; Hui-Yao Lan; Qionglin Liang; Guoan Luo; Ping Li
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 31-41
- ISSN:
- 0378-8741
- Subject:
- animal disease models; cortex; diabetic nephropathy; drugs; intraperitoneal injection; liquids; mass spectrometry; metabolites; metabolomics; phospholipids; protective effect; rats; renoprotective effect; streptozotocin; therapeutics; toxins; traditional medicine
- Abstract:
- ... Chaihuang-Yishen formula (CHYS) is a Chinese herbal formula that has been shown clinically to effectively treat chronic kidney disease including diabetic nephropathy (DN), also known as diabetic kidney disease. Our previous animal studies showed that numerous intrarenal metabolites were associated with the development of DN. In the present work, an integrated metabolomic and lipidomic analysis was ...
- DOI:
- 10.1016/j.jep.2015.02.019
- https://doi.org/10.1016/j.jep.2015.02.019
14. Metabolomics study of hematopoietic function of Angelica sinensis on blood deficiency mice model
- Author:
- Peng-ling Li; Hong-guo Sun; Yong-li Hua; Peng Ji; Ling Zhang; Jin-xia Li; Yanming Wei
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 261-269
- ISSN:
- 0378-8741
- Subject:
- Angelica sinensis; Oriental traditional medicine; animal models; arachidonic acid; arginine; biochemical pathways; biomarkers; biosynthesis; cyclophosphamide; erythrocytes; gas chromatography-mass spectrometry; hemoglobin; isoleucine; leucine; leukocytes; metabolites; metabolomics; principal component analysis; proline; serine; spleen; threonine; valine
- Abstract:
- ... Angelica sinensis (AS) has been used in traditional Chinese medicine for thousands of years to enrich and invigorate blood. In this study, the aim is to investigate the influence of AS on metabolism of blood deficiency mice model and to explore its anti-blood deficiency mechanism.The blood deficiency mice model was induced by being hypodermically injected with N-acetyl phenylhydrazine (APH) and be ...
- DOI:
- 10.1016/j.jep.2015.03.010
- https://doi.org/10.1016/j.jep.2015.03.010
- Author:
- Anwer Shah; Kumar Avinash Bharati; Javed Ahmad; M.P. Sharma
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 119-128
- ISSN:
- 0378-8741
- Subject:
- Allium; Angelica glauca; Arnebia; Asparagus racemosus; Balanophora; Cephalanthera longifolia; Cuscuta; Geranium; Gloriosa; Habenaria; Phyllanthus emblica; Ramaria; Verbascum thapsus; data analysis; herbs; leaves; livestock; medicinal plants; medicinal properties; snakes; surveys; tea; traditional medicine; tribal peoples; India
- Abstract:
- ... Medicinal plants are frequently employed by Gujjar and Bakerwal tribes in Rajouri and Poonch districts of Jammu and Kashmir, India for treatment of various ailments in humans and livestock. Hence, extensive field work was conducted to document the ethnomedicinal plants used by these tribes.Ninety one key informants were interviewed using both in situ and ex situ type of survey methods. The data we ...
- DOI:
- 10.1016/j.jep.2015.01.056
- https://doi.org/10.1016/j.jep.2015.01.056
- Author:
- J.R. Shubha; Praveena Bhatt
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 220-227
- ISSN:
- 0378-8741
- Subject:
- Escherichia coli; Lactobacillus plantarum; Plectranthus amboinicus; Salmonella Typhimurium; antimicrobial properties; bacteria; beta-galactosidase; buttermilk; chemical constituents of plants; diarrhea; digestive system; enzyme activity; ethnobotany; leaves; pathogens; phenolic acids; polyacrylamide gel electrophoresis; polyphenols; prebiotics; probiotics; selective media; sugars; traditional medicine; India
- Abstract:
- ... Leaves of Plectranthus amboinicus are consumed in India along with buttermilk (a probiotic source) during pathogen induced diarrhea. This treatment is known to reduce the number of episodes as well as duration of diarrhea.In the background of its ethnobotanical use, the present investigation was carried out to determine whether, apart from having an antimicrobial activity on pathogens, the leaves ...
- DOI:
- 10.1016/j.jep.2015.02.055
- https://doi.org/10.1016/j.jep.2015.02.055
- Author:
- Idris Ajayi Oyemitan; Omotola Aanuoluwa Olayera; Akeeb Alabi; Luqman Adewale Abass; Christianah Abimbola Elusiyan; Adebola Omowumi Oyedeji; Moses Atanda Akanmu
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 240-249
- ISSN:
- 0378-8741
- Subject:
- Piper guineense; alpha-pinene; anticonvulsants; behavior disorders; central nervous system; chemical composition; essential oils; fever; hydrodistillation; limonene; linalool; medicinal plants; mice; muscle relaxants; oils; raw fruit; rearing; sedatives; seizures; sesquiterpenoids; sleep; traditional medicine; Nigeria
- Abstract:
- ... Piper guineense Schum & Thonn (Piperaceae) is a medicinal plant used in the Southern States of Nigeria to treat fever, mental disorders and febrile convulsions.This study aims at determining the chemical composition and the central nervous system (CNS) activities of the essential oil obtained from the plant׳s fresh fruits in order to rationalize its folkloric use.Essential oil of P. guineense (EOP ...
- DOI:
- 10.1016/j.jep.2015.03.004
- https://doi.org/10.1016/j.jep.2015.03.004
- Author:
- Nannan Lai; Zhirong Zhang; Bin Wang; Xiuming miao; Yuqi Guo; Chengfang Yao; Zhaoxia Wang; Li Wang; Ruiping Ma; Xia Li; Guosheng Jiang
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 228-239
- ISSN:
- 0378-8741
- Subject:
- Western blotting; animal models; blood proteins; blood serum; bone density; bone resorption; collagen; correlation; dual-energy X-ray absorptiometry; enzyme-linked immunosorbent assay; eosin; estrogens; flow cytometry; interleukin-6; messenger RNA; mice; ovariectomy; protein content; protein synthesis; reverse transcriptase polymerase chain reaction; staining; tibia; traditional medicine
- Abstract:
- ... Bone loss is a common pathological condition induced by estrogen deficiency. The Th17/Treg paradigm, which can be skewed by estrogen, plays an important role in regulating bone metabolismThe purpose of this study was to determine the role of the Th17/Treg shift in estrogen deficiency-induced bone loss in mouse models and to elucidate the immunopharmacologic mechanism of Zuo-Gui-Wan (ZGW) in preven ...
- DOI:
- 10.1016/j.jep.2015.03.011
- https://doi.org/10.1016/j.jep.2015.03.011
- Author:
- Amal Yamani; Valérian Bunel; Marie-Hélène Antoine; Cécile Husson; Caroline Stévigny; Pierre Duez; Mostafa Elachouri; Joëlle Nortier
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 250-260
- ISSN:
- 0378-8741
- Subject:
- Aristolochia; Bryonia dioica; actin; aristolochic acids; beta catenin; cadherins; cell viability; common names; cytotoxicity; diabetes; digestive tract; excretion; fibronectins; fibrosis; fluorescence microscopy; genes; harvesters; herbs; kidney diseases; liquid chromatography; mass spectrometry; models; muscles; neoplasms; nephrotoxicity; patients; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; secretion; surveys; traditional medicine; urinary tract; vimentin; Morocco
- Abstract:
- ... Although acknowledged as toxic herbs, Aristolochia species are still widely used worldwide. The aristolochic acids (AA) they contain can induce the so-called “aristolochic acid nephropathy”, leading to renal fibrosis and upper urinary tract cancer. Traditional Moroccan medicine still often uses Aristolochia species under the vernacular name of Bereztem for the treatment of numerous ailments, notab ...
- DOI:
- 10.1016/j.jep.2015.03.036
- https://doi.org/10.1016/j.jep.2015.03.036
- Author:
- Ji-Won Han; Do-Wan Shim; Eun-Jeong Shim; Myong-Ki Kim; Yong-Kook Shin; Su-Bin Kwak; Sushruta Koppula; Tack-Joong Kim; Tae-Bong Kang; Kwang-Ho Lee
- Source:
- Journal of ethnopharmacology 2015 v.166 pp. 1-4
- ISSN:
- 0378-8741
- Subject:
- Syneilesis palmata; adenosine triphosphate; animal models; anti-inflammatory activity; arthritis; endotoxins; inflammasomes; inflammation; interleukin-1beta; macrophages; mice; nigericin; nitric oxide; pain; secretion; sepsis (infection); therapeutics; traditional medicine
- Abstract:
- ... Syneilesis palmata (Thunb.) Maxim. (S. palmata, Asteraceae) is a traditional Korean therapeutic herb widely used to treat pain, arthritis, and other symptoms. This study provides the scientific basis for the anti-inflammatory effects of S. palmata extract (SP) in both in vitro and in vivo experimental models.Lipopolysaccharide (LPS)-stimulated murine macrophages were used to study the regulatory e ...
- DOI:
- 10.1016/j.jep.2015.02.056
- https://doi.org/10.1016/j.jep.2015.02.056
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