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Journal of ethnopharmacology
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2014
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2014 v.152 no.1
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1. Antidepressant-like effects of Xiaochaihutang in a rat model of chronic unpredictable mild stress
- Author:
- Su, Guang Yue; Yang, Jing Yu; Wang, Fang; Ma, Jie; Zhang, Kuo; Dong, Ying Xu; Song, Shao Jiang; Lu, Xiu Mei; Wu, Chun Fu
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 217-226
- ISSN:
- 0378-8741
- Subject:
- animal models; antidepressants; dopamine; electrochemistry; food consumption; high performance liquid chromatography; hippocampus; immunohistochemistry; mechanism of action; nerve growth factor; neurotransmitters; rats; receptors; serotonin; staining; sucrose; therapeutics; traditional medicine; China
- Abstract:
- ... Xiaochaihutang (XCHT) has been used in China for thousands of years to treat “Shaoyang syndrome”, which involves depressive-like symptoms. However, few studies have investigated its antidepressant effects and pharmacological mechanism of action. The present study was designed to confirm the antidepressant effect of XCHT using a chronic unpredictable mild stress (CUMS) model and explore its potenti ...
- DOI:
- 10.1016/j.jep.2014.01.006
- http://dx.doi.org/10.1016/j.jep.2014.01.006
- Author:
- García-Galicia, Mary Carmen; Burgueño-Tapia, Eleuterio; Romero-Rojas, Andrés; García-Zebadúa, Julio César; Cornejo-Garrido, Jorge; Ordaz-Pichardo, Cynthia
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 91-98
- ISSN:
- 0378-8741
- Subject:
- Arracacia; aerial parts; alanine transaminase; animal disease models; aspartate transaminase; biometry; blood glucose; body weight changes; cytokines; diabetes mellitus; drugs; ethanol; ethyl acetate; glibenclamide; glycemic effect; hexane; histopathology; intraperitoneal injection; kidneys; lipids; liver; males; medicinal plants; pancreas; rats; spleen; streptozotocin; therapeutics; traditional medicine; Mexico
- Abstract:
- ... Arracacia tolucensis is a medicinal plant used in northeast of Mexico as a remedy to treat people with Diabetes mellitus (DM); however, there are no scientific studies that support this information. Thus, we evaluated the anti-hyperglycemic effect of the hexane, ethyl acetate and ethanol extracts from aerial parts in streptozotocin-induced diabetic rats.DM was induced in Wistar male rats by single ...
- DOI:
- 10.1016/j.jep.2013.12.031
- http://dx.doi.org/10.1016/j.jep.2013.12.031
- Author:
- Song, Hou-Pan; Li, Ru-Liu; Chen, Xu; Wang, Yi-Yu; Cai, Jia-Zhong; Liu, Jia; Chen, Wei-Wen
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 163-172
- ISSN:
- 0378-8741
- Subject:
- Atractylodes macrocephala; Oriental traditional medicine; Western blotting; alpha-difluoromethylornithine; calcium; cell movement; computer software; digestive system diseases; drugs; flow cytometry; high performance liquid chromatography; intestinal mucosa; membrane potential; messenger RNA; models; polystyrenes; potassium channels; protein content; protein synthesis; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction; spermidine
- Abstract:
- ... Atractylodes macrocephala Koidz (AMK) has been used widely as a digestive and tonic in traditional Chinese medicine. AMK has shown noteworthy promoting effect on intestinal epithelial cell migration, which might represent a promising candidate for the treatment of intestinal mucosa injury. The aim of this study was to investigate the efficacy of AMK on intestinal mucosal restitution and the underl ...
- DOI:
- 10.1016/j.jep.2013.12.049
- http://dx.doi.org/10.1016/j.jep.2013.12.049
- Author:
- Mukhija, Minky; Lal Dhar, Kanaya; Nath Kalia, Ajudhia
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 106-112
- ISSN:
- 0378-8741
- Subject:
- Zanthoxylum armatum; acridine orange; active ingredients; antineoplastic agents; apoptosis; bark; bioactive compounds; cell lines; cholera; cough; cytotoxicity; diabetes; diarrhea; ethidium; fever; fluorescence microscopy; headache; inflammation; inhibitory concentration 50; lignans; lung neoplasms; mass spectrometry; neoplasm cells; nuclear magnetic resonance spectroscopy; petroleum; silica gel; spectrophotometers; traditional medicine
- Abstract:
- ... Zanthoxylum alatum is used in traditional medicinal systems for number of disorders like cholera, diabetes, cough, diarrhea, fever, headache, microbial infections, toothache, inflammation and cancer. The aim of the present study was to evaluate Zanthoxylum alatum stem bark for its cytotoxic potential and to isolate the bioactive constitiuents.Cytotoxicity of the different extracts and isolated com ...
- DOI:
- 10.1016/j.jep.2013.12.039
- http://dx.doi.org/10.1016/j.jep.2013.12.039
- Author:
- Stefkov, Gjoshe; Miova, Biljana; Dinevska-Kjovkarovska, Suzana; Stanoeva, Jasmina Petreska; Stefova, Marina; Petrusevska, Gordana; Kulevanova, Svetlana
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 71-77
- ISSN:
- 0378-8741
- Subject:
- Centaurium; aerial parts; animal disease models; bitter-tasting compounds; blood; blood glucose; blood lipids; carbohydrate metabolism; chemical composition; cholesterol; diabetes; enzyme activity; flavonoids; formic acid; freeze drying; glibenclamide; glucose-6-phosphatase; glycemic effect; glycogen; high density lipoprotein; hyperglycemia; lipid metabolism; low density lipoprotein; maceration; mechanism of action; medicinal plants; methanol; phosphorylase; rats; secoiridoids; streptozotocin; traditional medicine; triacylglycerols; ultrasonics; xanthones; Balkans
- Abstract:
- ... Centaurium erythrea L. fam. Gentianaceae (CE) has been traditionally used for centuries in folk medicine of Balkans as a bitter medicinal herb for digestive complications and for treating febrile conditions and diabetes. The aim of this study was to gain insight into the chemical composition and underlying biochemical mechanism of action of the antihyperglycemic and antilipidemic activities of the ...
- DOI:
- 10.1016/j.jep.2013.11.047
- http://dx.doi.org/10.1016/j.jep.2013.11.047
- Author:
- Hook, Ingrid L.I.
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 1-13
- ISSN:
- 0378-8741
- Subject:
- Angelica sinensis; Oriental traditional medicine; clinical trials; ethnic differences; ferulic acid; herbal medicines; herbs; menopause; nationalities and ethnic groups; phthalides; plant biochemistry; polysaccharides; stir frying; wines; women; China; Europe; Japan; Korean Peninsula
- Abstract:
- ... Danggui (Chinese Angelica root; Dong quai; Angelica sinensis (Oliv.) Diels.) is a traditional Chinese herbal remedy with a long history of use in China, Korea and Japan. Even today it is still one of the herbs most commonly used by Traditional Chinese Medicine (TCM) practitioners in China, as well as Europe. It is mainly used for the treatment of women's reproductive problems, such as dysmenorrhea ...
- DOI:
- 10.1016/j.jep.2013.12.018
- http://dx.doi.org/10.1016/j.jep.2013.12.018
7. Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis
- Author:
- Umar, Anwar; Zhou, Wenting; Abdusalam, Elzira; Tursun, Arzigul; Reyim, Nadira; Tohti, Ibadet; Moore, Nicholas
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 151-155
- ISSN:
- 0378-8741
- Subject:
- Ocimum basilicum; animal models; butanol; chloroform; ethanol; ethyl acetate; human umbilical vein endothelial cells; macrophages; metabolites; mice; petroleum; prostacyclin; thrombosis; thromboxanes; traditional medicine
- Abstract:
- ... Ocimum basilicum L. (OBL) is a plant used in traditional Uyghur medicine for the treatment and prevention of cardiovascular disease. In previous studies we had found an antihypertensive and antithrombotic effect suggestive of an effect on prostaglandins, which we attempt to document here.6-keto-PGF1α, the metabolite of prostacyclin, and PGE2 were measured in the supernatant of human umbilical vein ...
- DOI:
- 10.1016/j.jep.2013.12.051
- http://dx.doi.org/10.1016/j.jep.2013.12.051
- Author:
- Xavier, Thangaraj Francis; Kannan, Moorthy; Lija, Leyone; Auxillia, Anthonysamy; Rose, Antony Kanthi Freeda; kumar, Subburaman Senthil
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 78-90
- ISSN:
- 0378-8741
- Subject:
- Aristolochia; Artocarpus heterophyllus; Artocarpus hirsutus; Chrysopogon zizanioides; Coscinium fenestratum; Curculigo orchioides; Elephantopus scaber; Gossypium hirsutum; Helicteres isora; Justicia adhatoda; Ocimum tenuiflorum; Pergularia daemia; Plumbago zeylanica; Pyrrosia; Smilax; Strychnos nux-vomica; bioassays; chemical constituents of plants; circulatory system; climatic factors; cough; data analysis; ethnobotany; fever; first aid; headache; health services; herbal medicines; herbs; hills; indigenous knowledge; interviews; liver; medicinal plants; new drugs; nontimber forest products; rare species; shrubs; toxicity testing; traditional medicine; vegetation; India
- Abstract:
- ... India is having a rich vegetation with a wide variety of plants, because of the extreme variations in geographical and climatic conditions prevailing in the country. Plants have been used since ancient times for the treatment of various ailments. Especially, Kani tribal communities in Thodu hills of Kerala meet their healthcare needs by using non-timber minor forest products and preparations based ...
- DOI:
- 10.1016/j.jep.2013.12.016
- http://dx.doi.org/10.1016/j.jep.2013.12.016
- Author:
- Kwon, Seung-Hwan; Ma, Shi-Xun; Hong, Sa-Ik; Kim, Sun Yeou; Lee, Seok-Yong; Jang, Choon-Gon
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 173-182
- ISSN:
- 0378-8741
- Subject:
- Eucommia ulmoides; Parkinson disease; abortion (animals); apoptosis; bark; chlorogenic acid; cytotoxicity; glycogen (starch) synthase; kidneys; liver; longevity; lungs; mitochondria; mitochondrial membrane; mitogen-activated protein kinase; muscles; neurons; neuroprotective effect; neurotoxins; oxidative stress; phosphatidylinositol 3-kinase; phosphorylation; reactive oxygen species; traditional medicine; transcription factor NF-kappa B; Korean Peninsula
- Abstract:
- ... Eucommia ulmoides Oliv. Bark. (EUE) has commonly been used to fortify the muscles and lungs, lower blood pressure, prevent miscarriage, improve liver and kidney tone, and promote longevity as a traditional tonic medicine in Korea, China, and Japan.In this study, we investigated the mechanisms by which EUE protects neuronal cells from apoptosis induced by the Parkinson's disease (PD)-related neurot ...
- DOI:
- 10.1016/j.jep.2013.12.048
- http://dx.doi.org/10.1016/j.jep.2013.12.048
- Author:
- Dong, Yizhu; Huang, Jianchun; Lin, Xing; Zhang, Shijun; Jiao, Yang; Liang, Tao; Chen, Zhaoni; Huang, Renbin
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 201-206
- ISSN:
- 0378-8741
- Subject:
- Millettia; alanine transaminase; animal models; aspartate transaminase; drugs; glutathione peroxidase; hepatoprotective effect; ingredients; intragastric administration; isoniazid; lipid peroxidation; liver; memory; mice; polysaccharides; rifampicin; superoxide dismutase; traditional medicine; China
- Abstract:
- ... Yulangsan polysaccharide (YLSPS) is often used in popular folk medicine in the Guangxi Zhuang Autonomous Region of China as a chief ingredient of Millettia pulchra, which is used as an hepatic protection, anti-aging and memory improving agent. In this study, the hepatoprotective effects of YLSPS against isoniazid (INH) or rifampicin and isoniazid (RFP+INH)-induced liver injury were investigated in ...
- DOI:
- 10.1016/j.jep.2014.01.001
- http://dx.doi.org/10.1016/j.jep.2014.01.001
- Author:
- Shil, Sanjib; Dutta Choudhury, Manabendra; Das, Soumita
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 135-141
- ISSN:
- 0378-8741
- Subject:
- Cyathea; acculturation; blood coagulation; chemical constituents of plants; deforestation; fever; flora; health services; indigenous knowledge; inflammation; leaves; medicinal plants; nationalities and ethnic groups; pain; questionnaires; surveys; traditional medicine; traditions; tree ferns; India
- Abstract:
- ... Traditional remedies used for the treatment of various ailments are considered to be very important in the primary health care of Reang people living in Tripura state of Northeast India. Novel information gathered from the present investigation is important in preserving folk indigenous knowledge of Reang tribe.Systematic and exhaustive field surveys were conducted during 2003 to 2004 in Reang inh ...
- DOI:
- 10.1016/j.jep.2013.12.037
- http://dx.doi.org/10.1016/j.jep.2013.12.037
- Author:
- Shang, Xiaofei; Pan, Hu; Wang, Xuezhi; He, Hua; Li, Maoxing
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 14-32
- ISSN:
- 0378-8741
- Subject:
- Internet; Leonurus japonicus; Oriental traditional medicine; active ingredients; aerial parts; alkaloids; amenorrhea; cardioprotective agents; diterpenoids; edema; flavones; health services; pharmacology; therapeutics; toxicity; toxicology; uterus; women; China
- Abstract:
- ... Leonurus japonicus Houtt. (Labiatae), commonly called Chinese motherwort (▪▪▪), is an herbaceous flowering plant native to Asia. For thousands of years in China, the aerial part of Leonurus japonicus has been used to treat menoxenia, dysmenorrhea, amenorrhea, lochia, edema of the body, oliguresis, sores, ulcerations and other diseases in women. Now, Leonurus japonicus is listed in the Pharmacopoei ...
- DOI:
- 10.1016/j.jep.2013.12.052
- http://dx.doi.org/10.1016/j.jep.2013.12.052
- Author:
- Jin, Gui-Lin; Su, Yan-Ping; Liu, Ming; Xu, Ying; Yang, Jian; Liao, Kai-Jun; Yu, Chang-Xi
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 33-52
- ISSN:
- 0378-8741
- Subject:
- Gelsemium sempervirens; Oriental traditional medicine; analgesics; anxiety; asthma; chemical constituents of plants; databases; indole alkaloids; mechanism of action; medicinal plants; migraine; monoterpenoids; neoplasms; pain; pharmacology; poisonous plants; surveys; therapeutics; toxicity; toxicology; tranquilizers; whooping cough; North America; South East Asia
- Abstract:
- ... In the genus Gelsemium, Gelsemium elegans (Gardn. & Champ.) Benth. has been recognized as a toxic plant that is widely distributed in Southeast Asia and has been used as traditional Chinese medicine for the treatment of rheumatoid pain, neuropathic pain, spasticity, skin ulcers and cancers for many years. Gelsemium sempervirens (L.) J.St.-Hil. has been used since the nineteenth century in homeopat ...
- DOI:
- 10.1016/j.jep.2014.01.003
- http://dx.doi.org/10.1016/j.jep.2014.01.003
- Author:
- Menendez-Baceta, Gorka; Aceituno-Mata, Laura; Molina, María; Reyes-García, Victoria; Tardío, Javier; Pardo-de-Santayana, Manuel
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 113-134
- ISSN:
- 0378-8741
- Subject:
- Anagallis arvensis; Chamaemelum nobile; Chelidonium majus; Coronopus; Helleborus; Internet; Liliaceae; Plantago; Urtica dioica; Verbena officinalis; data collection; developed countries; drugs; environmental factors; ethnobotany; indigenous knowledge; interviews; leaves; medicinal plants; men; new species; public health; surveys; traditional medicine; Iberian Peninsula
- Abstract:
- ... Many ethnobotanical studies show that people in industrial countries still rely on their traditional knowledge of medicinal plants for self-treatment, although the trend might not be as common as some decades ago. Given the social and public health implications of ethnopharmacological practices, this survey aims at recording and analysing the medicinal plants used in the folk medicine of the North ...
- DOI:
- 10.1016/j.jep.2013.12.038
- http://dx.doi.org/10.1016/j.jep.2013.12.038
- Author:
- Hannan, Md. Abdul; Kang, Ji-Young; Mohibbullah, Md.; Hong, Yong-Ki; Lee, HyunSook; Choi, Jae-Suk; Choi, In Soon; Moon, Il Soo
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 142-150
- ISSN:
- 0378-8741
- Subject:
- Ayurvedic medicine; Moringa oleifera; animal models; beta-carotene; cell death; computer software; ethanol; lactate dehydrogenase; leaves; lipophilicity; morphometry; nerve tissue; neurites; neuroprotective effect; nutrition; paralysis; synaptogenesis; viability
- Abstract:
- ... Moringa oleifera Lam. (Moringaceae) by virtue of its high nutritional as well as ethnomedical values has been gaining profound interest both in nutrition and medicinal research. The leaf of this plant is used in ayurvedic medicine to treat paralysis, nervous debility and other nerve disorders. In addition, research evidence also suggests the nootropic as well as neuroprotective roles of Moringa ol ...
- DOI:
- 10.1016/j.jep.2013.12.036
- http://dx.doi.org/10.1016/j.jep.2013.12.036
- Author:
- Bin Sayeed, Muhammad Shahdaat; Shams, Tahiatul; Fahim Hossain, Sarder; Rahman, Md. Rezowanur; Mostofa, AGM; Fahim Kadir, Mohammad; Mahmood, Sharif; Asaduzzaman, Md.
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 156-162
- ISSN:
- 0378-8741
- Subject:
- Nigella sativa; adolescents; anxiety; cognition; inventories; males; memory; seeds; traditional medicine; Bangladesh; California
- Abstract:
- ... Previous studies conducted on animals linked consumption of Nigella sativa L. seeds (NS) to decreased anxiety and improved memory. The present study, which was carried out at a boarding school in Bangladesh, was designed to examine probable effect of NS on mood, anxiety and cognition in adolescent human males.Forty-eight healthy adolescent human males aged between 14 to 17 years were randomly recr ...
- DOI:
- 10.1016/j.jep.2013.12.050
- http://dx.doi.org/10.1016/j.jep.2013.12.050
- Author:
- Kon, Risako; Ikarashi, Nobutomo; Nagoya, Chika; Takayama, Tomoko; Kusunoki, Yoshiki; Ishii, Makoto; Ueda, Harumi; Ochiai, Wataru; Machida, Yoshiaki; Sugita, Kazuyuki; Sugiyama, Kiyoshi
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 190-200
- ISSN:
- 0378-8741
- Subject:
- colon; colorectal neoplasms; diarrhea; epithelial cells; indomethacin; macrophage activation; macrophages; metabolites; prostaglandins; rats; rhubarb; secretion; traditional medicine; water content
- Abstract:
- ... Aquaporin-3 (AQP3) is expressed in mucosal epithelial cells in the colon and is important for regulating fecal water content. We examined the role of AQP3 in the laxative effect of rhubarb extract.After orally administering rhubarb extract or its major component (sennoside A) to rats, the fecal water content, AQP3 expression and prostaglandin E2 (PGE2) concentrations in the colon were examined. Th ...
- DOI:
- 10.1016/j.jep.2013.12.055
- http://dx.doi.org/10.1016/j.jep.2013.12.055
- Author:
- Xing, Shihua; Wang, Mengyue; Peng, Ying; Chen, Daofeng; Li, Xiaobo
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 183-189
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Scutellaria baicalensis; agar; antimicrobial properties; baicalin; cardiovascular diseases; gastric juice; gastrointestinal system; hemolysis; high performance liquid chromatography; inflammation; intestinal microorganisms; intestinal secretions; medicinal properties; metabolism; metabolites; roots; spectral analysis
- Abstract:
- ... .Georgi (Labiatae) is a well-known traditional Chinese medicine to treat inflammation, cardiovascular diseases, respiratory and gastrointestinal infections, etc. The present study was to understand the metabolism of the root of Scutellaria baicalensis (a.k.a. Huangqin in Chinese) in the gastrointestinal tract and the correlation between the metabolites and their respective pharmacological activiti ...
- DOI:
- 10.1016/j.jep.2013.12.056
- http://dx.doi.org/10.1016/j.jep.2013.12.056
- Author:
- Niu, Xiaofeng; Li, Yongmei; Li, Weifeng; Hu, Hua; Yao, Huan; Li, Huani; Mu, Qingli
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 99-105
- ISSN:
- 0378-8741
- Subject:
- Caragana; Oriental traditional medicine; acetic acid; animal models; anti-inflammatory activity; arthritis; carrageenan; dose response; ears; edema; ethyl acetate; fever; immunohistochemistry; inflammation; lungs; mice; pain; prostaglandin synthase; prostaglandins; rats
- Abstract:
- ... Caragana tangutica KOM has been used to treat arthritis, wounds, fever and other disease conditions in traditional Chinese medicine (TMC). To support the application of the plant in traditional Chinese medicine by investigating the anti-inflammatory effects of the ethyl acetate extract of Caragana tangutica.The anti-inflammatory activity was evaluated by animal models including xylene-induced ear ...
- DOI:
- 10.1016/j.jep.2013.12.026
- http://dx.doi.org/10.1016/j.jep.2013.12.026
- Author:
- Bhatia, Harpreet; Manhas, R.K.; Kumar, Kewal; Magotra, Rani
- Source:
- Journal of ethnopharmacology 2014 v.152 no.1 pp. 207-216
- ISSN:
- 0378-8741
- Subject:
- Calotropis procera; Cannabis sativa; Carica; Cuscuta reflexa; Embelia; Euphorbia helioscopia; Euphorbia hirta; Leucaena leucocephala; Parthenium hysterophorus; Prunus persica; Senna occidentalis; Solanaceae; Urtica dioica; chemical constituents of plants; data collection; death; financial economics; gastrointestinal system; herbaria; herbs; indigenous knowledge; interviews; leaves; livestock and meat industry; poisonous plants; toxicity; traditional medicine; India
- Abstract:
- ... Poisonous plants comprise the third largest category of poisons known around the world. Other than affecting the humans directly, they are the major cause of economic losses in the livestock industry since the advent of civilisation. Aim of the present study was to collect and systematically document the traditional knowledge of poisonous plants of Udhampur District for the benefit of humanity bef ...
- DOI:
- 10.1016/j.jep.2013.12.058
- http://dx.doi.org/10.1016/j.jep.2013.12.058