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You searched for: Journal name Journal of ethnopharmacology Remove constraint Journal name: Journal of ethnopharmacology Publication year rev 7988-2012 Remove constraint Publication year rev: 7988-2012 Source 2012 v.142 no.1 Remove constraint Source: 2012 v.142 no.1
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1. Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes

Author:
Feng-Ming Ho; Yi-Hsiang Liao; Ai-Jen Yang; Pei-Dawn Lee Chao; Yu-Chi Hou; Chen-Tsung Huang; Shu-Rung Lin; Kueir-Rarn Lee; Kuo-Chin Huang; Wan-Wan Lin
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 175-187
ISSN:
0378-8741
Subject:
atherosclerosis; berberine; blood lipids; cell proliferation; cholesterol; collagen; daidzein; daidzin; diet; glucose; glycyrrhizin; hepatocytes; herbal medicines; high density lipoprotein; high performance liquid chromatography; lipemic effect; low density lipoprotein; macrophages; mechanism of action; medicine; mice; models; myocytes; smooth muscle
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The Ger-Gen-Chyn-Lian-Tang (GGCLT), an officially standardized mixture of Chinese herbal medicines, consists of Puerariae Radix, Scutellariae Radix, Coptidis Rhizoma and Glycyrrhizae Radix in a ratio of 8:3:3:2. In this study, we evaluated the benefits of GGCLT in atherosclerotic progression. METHODS: The major constituents of GGCLT were analyzed by HPLC. ApoE⁻/⁻ mi ...
DOI:
10.1016/j.jep.2012.04.034
PubMed:
22543166

2. Anti-hyperuricemic and nephroprotective effects of Modified Simiao Decoction in hyperuricemic mice

Author:
Jian Hua; Ping Huang; Chong-Mei Zhu; Xiao Yuan; Chen-Huan Yu
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 248-252
ISSN:
0378-8741
Subject:
Western blotting; allopurinol; anions; creatinine; excretion; kidneys; liver; mice; models; oxidative stress; protein synthesis; superoxide dismutase; transporters; uric acid; urine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Modified Simiao Decoction (MSD), based on clinical experience, has been used for decades and famous for its efficiency in treating hyperuricemic and gouty diseases. AIM OF THE STUDY: To investigate the effects of MSD on anti-hyperuricemic and nephroprotective effects are involved in potassium oxonate-induced hyperuricemic mice. MATERIALS AND METHODS: The effects of ...
DOI:
10.1016/j.jep.2012.04.052
PubMed:
22575704

3. Antibiotics attenuate anti-scratching behavioral effect of ginsenoside Re in mice

Author:
Se-Eun Jang; Il-Hoon Jung; Eun-Ha Joh; Myung Joo Han; Dong-Hyun Kim
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 105-112
ISSN:
0378-8741
Subject:
Panax ginseng; diabetes; histamine; mice; microorganisms; oral administration; oxytetracycline; roots; streptomycin; tetracycline; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The root of Panax ginseng CA Meyer (ginseng) has been used for diabetes, cancer, stress and allergic diseases in the traditional Chinese medicine. AIM OF THE STUDY: To understand the role of intestinal microflora in the pharmacological effect of ginsenoside Re, which is a main constituent of ginseng, we investigated its anti-scratching behavioral effect in the mice ...
DOI:
10.1016/j.jep.2012.04.022

4. Anticonvulsant and antioxidative activity of hydroalcoholic extract of tuber of Orchis mascula in pentylenetetrazole and maximal electroshock induced seizures in rats

Author:
Monika Pahuja; Jogender Mehla; Yogendra Kumar Gupta
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 23-27
ISSN:
0378-8741
Subject:
Orchis; anticonvulsants; antioxidant activity; brain; glutathione; lipid peroxidation; memory; nerve tissue; oral administration; oxidative stress; rats; seizures; tubers; India
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Orchis mascula tuber is used in many polyherbal formulations as a nerve tonic in India. AIM OF THE STUDY: In the present study, effect of hydroalcholic extract of O. mascula (HEOM) tuber was evaluated against seizures, seizure-induced oxidative stress and cognitive deficit in pentylenetetrazole and maximal electroshock-induced seizures in rats. MATERIALS AND METHODS ...
DOI:
10.1016/j.jep.2012.04.006
PubMed:
22575841

5. Antidiabetic and antioxidant potential of Emblica officinalis Gaertn. leaves extract in streptozotocin-induced type-2 diabetes mellitus (T2DM) rats

Author:
Parminder Nain; Vipin Saini; Sunil Sharma; Jaspreet Nain
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 65-71
ISSN:
0378-8741
Subject:
Phyllanthus emblica; alkaline phosphatase; antioxidant activity; bark; blood glucose; blood serum; catalase; cholesterol; creatinine; diabetes mellitus; diarrhea; flowers; free radical scavengers; fruits; glutathione; glutathione peroxidase; glycemic effect; insulin; kidneys; leaf extracts; leaves; lipid peroxidation; liver; oral administration; oxidative stress; protective effect; rats; risk; roots; seeds; streptozotocin; superoxide dismutase; traditional medicine; transaminases; triacylglycerols; urea
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: In traditional Indian medicine, all parts of Emblica officinalis Gaertn plant including the fruit, seed, leaves, root, bark and flowers are used in various herbal preparations for the treatment of diabetes mellitus, chronic diarrhea, anti-inflammatory and antipyretic. AIM OF THE STUDY: To evaluate the hypoglycemic and antioxidants effects of the hydro-methanolic (20 ...
DOI:
10.1016/j.jep.2012.04.014

6. Antihistaminic and antiallergic actions of extracts of Solanum nigrum berries: Possible role in the treatment of asthma

Author:
S.A. Nirmal; A.P. Patel; S.B. Bhawar; S.R. Pattan
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 91-97
ISSN:
0378-8741
Subject:
Solanum nigrum; allergens; asthma; clonidine; eosinophilia; ethanol; ethers; guinea pigs; haloperidol; histamine; ileum; leukocyte count; mast cells; mice; petroleum; small fruits; smooth muscle; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Berries of the plant Solanum nigrum Linn (Solanaceae) are used for the treatment of asthma in folk medicine and ancient books. AIM OF STUDY: To evaluate potential of the plant berries in the treatment of asthma. MATERIALS AND METHODS: Petroleum ether, ethanol and aqueous extracts of S. nigrum berries (50, 100 and 200mg/kg, i.p.) were screened for the treatment of as ...
DOI:
10.1016/j.jep.2012.04.019
PubMed:
22564816

7. Antitumor activity of the methanolic extract of Ammannia baccifera L. against Dalton's ascites lymphoma induced ascitic and solid tumors in mice

Author:
Nataraj Loganayaki; Sellamuthu Manian
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 305-309
ISSN:
0378-8741
Subject:
Ammannia; Ayurvedic medicine; albino; antineoplastic agents; antioxidants; ascites; bromides; cytotoxicity; erythrocytes; fasting; growth models; hemoglobin; humans; lipid peroxidation; longevity; lymphocyte count; lymphoma; medicinal plants; methanol; mice; plant development; plant extracts; therapeutics; uterine cervical neoplasms; India
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: India is a rich source of medicinal plants and a number of plant extracts are used against diseases in various systems of medicine such as Ayurveda, Unani and Siddha. Only a few of them have been scientifically explored. One of such plants is Ammannia baccifera L., traditionally used as an antitumor agent. AIM OF THE STUDY: The objective of the present study was to ...
DOI:
10.1016/j.jep.2012.05.008
PubMed:
22613234

8. Effect of Sophora flavescens Aiton extract on degranulation of mast cells and contact dermatitis induced by dinitrofluorobenzene in mice

Author:
Hyungwoo Kim; Mi Ran Lee; Guem San Lee; Won Gun An; Su In Cho
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 253-258
ISSN:
0378-8741
Subject:
histamine; traditional medicine; anti-inflammatory activity; reaction inhibition; topical application; fever; interferon-gamma; ears; models; mice; tumor necrosis factor-alpha; edema; mast cells; patients; paints; roots; Sophora flavescens; contact dermatitis; hyperplasia
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The dried root of Sophora flavescens Aiton (Sophorae radix, SR) has long been used in traditional medicine for the treatment of fever and swelling in eastern countries. MATERIALS AND METHODS: The present study investigated the anti-allergic and anti-inflammatory effects of SR using 1-fluoro-2,4-dinitrofluorobenzene (DNFB)-induced contact dermatitis mouse model and i ...
DOI:
10.1016/j.jep.2012.04.053
PubMed:
22580027

9. Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats

Author:
Hsien-Tsung Yao; Yi-Wei Chang; Naoto Uramaru; Yoko Watanabe; Shigeyuki Kitamura; Yueh-Hsiung Kuo; Chong-Kuei Lii; Teng-Kuang Yeh
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 121-128
ISSN:
0378-8741
Subject:
blood glucose; enzyme activity; glutathione transferase; high performance liquid chromatography; liver; liver microsomes; liver protein; mass spectrometry; medicinal plants; oral administration; protein synthesis; rats; tolbutamide; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Bu-Zhong-Yi-Qi-Tang (BT) is the dry powder derived from the aqueous extract of a mixture of 10 medicinal herbs. It is a traditional Chinese medicine being used for the treatment of various immune-related diseases. AIM OF THE STUDY: To investigate the effect of BT on hepatic drug-metabolizing enzymes and its effect on plasma concentrations of tolbutamide, a substrate ...
DOI:
10.1016/j.jep.2012.04.024
PubMed:
22564357

10. Effects of Schisandra chinensis Baillon (Schizandraceae) on lipopolysaccharide induced lung inflammation in mice

Author:
Hyunsu Bae; Ranah Kim; Youngeun Kim; Euijeong Lee; Hye Jin Kim; Young Pyo Jang; Sung-Ki Jung; Jinju Kim
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 41-47
ISSN:
0378-8741
Subject:
Schisandra chinensis; enzyme-linked immunosorbent assay; herbs; humans; in vivo studies; inflammation; lipopolysaccharides; lungs; mice; nitric oxide; oral administration; pneumonia; secretion; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Schisandra chinensis Baillon (Sc), an anti-inflammatory herb that has been used in traditional Chinese medicine for thousands of years, is frequently used to treat upper respiratory tract infections. AIM OF THE STUDY: This study was conducted to evaluate the ability of a water extract of Sc to prevent airway inflammation both in vitro and in vivo. MATERIALS AND METH ...
DOI:
10.1016/j.jep.2012.04.009
PubMed:
22543173

11. Evaluation of antimicrobial activity of ethanol extract and compounds isolated from Trichodesma indicum (Linn.) R. Br. root

Author:
James B. Perianayagam; S.K. Sharma; K.K. Pillai; A. Pandurangan; D. Kesavan
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 283-286
ISSN:
0378-8741
Subject:
Trichodesma; antibacterial properties; dysentery; ethanol; fever; in vitro studies; leprosy; microorganisms; minimum inhibitory concentration; roots; skin diseases; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The roots are reportedly used to treat diarrhoea, dysentery, leprosy, skin diseases and fever. AIM OF STUDY: The aim of present study was to investigate the in vitro antimicrobial potential of ethanol extract of Trichdesma indicum root, and its purified compounds and to validate scientifically its use in traditional medicine. MATERIAL AND METHODS: The root of Trichd ...
DOI:
10.1016/j.jep.2012.04.020
PubMed:
22543169

12. Food- and gender-dependent pharmacokinetics of paeoniflorin after oral administration with Samul-tang in rats

Author:
Youn-Hwan Hwang; Taesoo Kim; Won-Kyung Cho; Doorye Jang; Jung-Ho Ha; Jin Yeul Ma
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 161-167
ISSN:
0378-8741
Subject:
Angelica gigas; Cnidium; Paeonia lactiflora; Rehmannia glutinosa; absorption; analysis of variance; bioavailability; food intake; gender differences; high performance liquid chromatography; neuroprotective effect; oral administration; pharmacokinetics; rats; research methods; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Samul-tang (Si-Wu-tang in Chinese, Shimotsu-to in Japanese), widely used in eastern Asia, is composed of Angelica gigas (Angelicae Gigantis Radix), Cnidium officinale (Cnidii Rhizoma), Paeonia lactiflora (Paeonia Radix) and Rehmannia glutinosa (Rehmanniae Radix Preparata). Paeoniflorin, one of active components in Samul-tang has anti-platelet, anti-inflammation, ant ...
DOI:
10.1016/j.jep.2012.04.032
PubMed:
22543167

13. High molecular weight polysaccharides are key immunomodulators in North American ginseng extracts: Characterization of the ginseng genetic signature in primary human immune cells

Author:
Holly R. Lemmon; Jane Sham; Luan A. Chau; Joaquín Madrenas
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 1-13
ISSN:
0378-8741
Subject:
Panax quinquefolius; cytokines; enzyme-linked immunosorbent assay; fractionation; humans; immune response; immunomodulators; ingredients; microarray technology; mitogen-activated protein kinase; molecular weight; mononuclear leukocytes; phosphatidylinositol 3-kinase; polysaccharides; traditional medicine; North America
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Ginseng (GS) has played a pivotal role in traditional Chinese medicine for thousands of years. Its use has become increasingly popular in North America, in part due to the many claims of its immune-enhancing properties. The immunopharmacology of the North American variety of GS and its extracts is needed to substantiate these claims. MATERIALS AND METHODS: Human per ...
DOI:
10.1016/j.jep.2012.04.004
PubMed:
22521964

14. In vitro anti-breast cancer activity of ethanolic extract of Wrightia tomentosa: Role of pro-apoptotic effects of oleanolic acid and urosolic acid

Author:
Bandana Chakravarti; Ranjani Maurya; Jawed Akhtar Siddiqui; Hemant Kumar Bid; S.M. Rajendran; Prem P. Yadav; Rituraj Konwar
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 72-79
ISSN:
0378-8741
Subject:
DNA fragmentation; Wrightia; apoptosis; breast neoplasms; cell cycle; cell proliferation; ethanol; hexane; leaves; membrane potential; oleanolic acid; reactive oxygen species; snake bites; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Wrightia tomentosa Roem. & Schult. (Apocynaceae) is known in the traditional medicine for anti-cancer activity along with other broad indications like snake and scorpion bites, renal complications, menstrual disorders etc. However, the anti-cancer activity of this plant or its constituents has never been studied systematically in any cancer types so far. AIM OF THE ...
DOI:
10.1016/j.jep.2012.04.015

15. Neuroprotective activity of Cymbopogon martinii against cerebral ischemia/reperfusion-induced oxidative stress in rats

Author:
Prakruti Buch; Vishal Patel; Vishavas Ranpariya; Navin Sheth; Sachin Parmar
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 35-40
ISSN:
0378-8741
Subject:
Cymbopogon martinii; albino; anorexia; brain; brain damage; carotid arteries; catalase; essential oils; glutathione; histopathology; ischemia; lipid peroxidation; neuroprotective effect; oxidative stress; rats; stroke; superoxide dismutase; thiols
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Cymbopogon martinii (Roxb.) Watson (Family: Graminae), commonly known as Palmarosa, is traditionally prescribed for central nervous system (CNS) disorders such as neuralgia, epileptic fits and anorexia. Although the plant possesses diverse pharmacological actions, the neuroprotective action has got little attention. AIM OF THE STUDY: The present study evaluated neur ...
DOI:
10.1016/j.jep.2012.04.007

16. Pharmacological basis for the medicinal use of muskmelon base (Pedicellus Melo.) for abdominal distention and constipation

Author:
Yuan Gao; Run-Lan Cai; Chen Xie; Yu-Lin Lin; Lei Zhang; Yun Qi
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 129-135
ISSN:
0378-8741
Subject:
acute toxicity; atropine; colon; constipation; drug therapy; gastric emptying; guinea pigs; in vivo studies; mice; muscle strength; muskmelons; purgative properties; rats; smooth muscle; stomach; toxicity testing; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Muskmelon base (Pedicellus Melo.) has a long history (Ming Dynasty) as a Chinese traditional medicine. According to traditional use, it was prepared as rectal suppositories for treating abdominal distention and constipation. The present study was carried out on the pharmacological basis for the medicinal use of muskmelon base. AIM OF THE STUDY: The objective of this ...
DOI:
10.1016/j.jep.2012.04.025
PubMed:
22543170

17. Rhus parviflora and its biflavonoid constituent, rhusflavone, induce sleep through the positive allosteric modulation of GABAA-benzodiazepine receptors

Author:
Sabina Shrestha; Ji-Hae Park; Dae-Young Lee; Jin-Gyeong Cho; Suengmok Cho; Hye-Jin Yang; Hye-Im Yong; Min-Seok Yoon; Dae-Seok Han; Nam-In Baek
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 213-220
ISSN:
0378-8741
Subject:
Ayurvedic medicine; Rhus; acetates; binding sites; fruits; ketones; methanol; mice; oral administration; pentobarbital; receptors; sleep; stomach
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Rhus parviflora is referred as ‘Tintidikah’ in traditional medicinal system of south Asia (Ayurveda). It is used in treatment of Vāta vikāra, a condition related to neurological complications as well as cure for stomach disorders. MATERIALS AND METHODS: Dried and powdered fruits of R. parviflora were extracted with 80% aqueous methanol (RPME). The concentrated extra ...
DOI:
10.1016/j.jep.2012.04.047
PubMed:
22579675

18. Salacia oblonga ameliorates hypertriglyceridemia and excessive ectopic fat accumulation in laying hens

Author:
Jianwei Wang; Xianglu Rong; Wenlong Li; Johji Yamahara; Yuhao Li
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 221-227
ISSN:
0378-8741
Subject:
Ayurvedic medicine; animal models; blood glucose; diabetes; food intake; glucose; heart; hypertriglyceridemia; laying hens; lipid metabolism; liver; obesity; pullets; roots; skeletal muscle; triacylglycerols
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Salacia oblonga root (SOR) is an Ayurvedic medicine for obesity and diabetes, those are associated with glucose and lipid metabolism. AIM OF THE STUDY: SOR has been demonstrated previously to improve glucose and lipid metabolism in animal models of obesity and diabetes and to be a peroxisome proliferator-activated receptor-alpha activator. However, the anti-obesogen ...
DOI:
10.1016/j.jep.2012.04.048
PubMed:
22561158

19. Topical application of Acalypha indica accelerates rat cutaneous wound healing by up-regulating the expression of Type I and III collagen

Author:
Moorthy Ganeshkumar; Thangavel Ponrasu; Rajesh Krithika; Kuttalam Iyappan; Vinaya Subramani Gayathri; Lonchin Suguna
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 14-22
ISSN:
0378-8741
Subject:
Acalypha indica; antioxidant activity; ascorbic acid; body weight; collagen; enzyme-linked immunosorbent assay; excision; granulation tissue; histopathology; lipid peroxidation; medicine; oxidative stress; rats; shrinkage; temperature; tensile strength; tissue repair; topical application; transforming growth factors; tribal peoples; tumor necrosis factors; wound treatment; India
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Acalypha indica Linn. (Acalypha indica) vernacularly called Kuppaimeni in Tamil, has been used as a folklore medicine since ages for the treatment of wounds by tribal people of Tamil Nadu, Southern India. The present study investigates the biochemical and molecular rationale behind the healing potential of Acalypha indica on dermal wounds in rats. MATERIAL AND METHO ...
DOI:
10.1016/j.jep.2012.04.005
PubMed:
22521732

20. Vasodilatory effects of ethanol extract of Radix Paeoniae Rubra and its mechanism of action in the rat aorta

Author:
Song Nan Jin; Jin Fu Wen; Ting Ting Wang; Dae Gill Kang; Ho Sub Lee; Kyung Woo Cho
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 188-193
ISSN:
0378-8741
Subject:
Paeonia lactiflora; adrenergic receptors; aorta; ethanol; heart; liver; mechanism of action; rats; smooth muscle; traditional medicine; vasodilation; China
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Radix Paeoniae Rubra (RPR) is an important traditional Chinese medicine (TCM) commonly used in clinic for a long history in China. RPR is the radix of either Paeonia lactiflora Pall. or Paeonia veitchii Lynch. RPR has a wide variety of pharmacological actions such as anti-thrombus, anti-coagulation, and anti-atherosclerotic properties, protecting heart and liver. Ho ...
DOI:
10.1016/j.jep.2012.04.035
PubMed:
22543176