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1. A novel property of propolis (bee glue): Anti-pathogenic activity by inhibition of N-acyl-homoserine lactone mediated signaling in bacteria

Author:
Bulman, Zackery; Le, Phuong; Hudson, André O.; Savka, Michael A.
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 788-797
ISSN:
0378-8741
Subject:
Apoidea; Chromobacterium violaceum; Escherichia coli; Pseudomonas aeruginosa; absorption; antibiotics; bacteria; bioassays; biosensors; harvesting; monitoring; pathogens; propolis; quorum sensing; therapeutics
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: An alternative approach to antibiotics is the development of anti-pathogenic agents to control the bacterial virulome. Such anti-pathogenic agents could target a phenomena known as quorum sensing (QS). MATERIALS AND METHODS: Six bacterial N-acyl-homoserine lactone (AHL)-dependent bioreporter strains were used to evaluate if bee hive glue also known as propolis conta ...
DOI:
10.1016/j.jep.2011.10.029
PubMed:
22063726

2. Antiarthritic activity of various extracts of Mesua ferrea Linn. seed

Author:
Jalalpure, Sunil S.; Mandavkar, Yuvaraj D.; Khalure, Pallavi R.; Shinde, Gulab S.; Shelar, Pournima A.; Shah, Amol S.
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 700-704
ISSN:
0378-8741
Subject:
Elapidae; Mesua; adjuvants; arthritis; body weight changes; flowers; formaldehyde; leaves; pain; protective effect; rats; saffron; seeds; tropical wood; tropics
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Mesua ferrea Linn. (Cluciaseae), Cobra's saffron, is named after the heaviness of its timber and is cultivated in tropical climates for its form, foliage, and fragrant flowers. It is prescribed in the Ayurvedic literature for the treatment of pain, inflammation, and rheumatic conditions. OBJECTIVE: In present investigation, activity of Mesua ferrea and its evaluatio ...
DOI:
10.1016/j.jep.2011.09.042
PubMed:
21986230

3. Anticonvulsant activity of the methanolic extract of Justicia extensa T. Anders

Author:
Sowemimo, Abimbola Adepeju; Adio, Olawale; Fageyinbo, Samuel
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 697-699
ISSN:
0378-8741
Subject:
Justicia; diazepam; leaf extracts; mice; models; seizures; strychnine; toxicity
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: To investigate the anticonvulsant activity of the leaf extract of Justicia extensa T. Anders used traditionally in the treatment of convulsion. MATERIALS AND METHODS: The anticonvulsant activity of the methanolic extract of Justicia extensa (50, 100 and 200mg/kg, p.o.) was assessed in strychnine-induced (STR) and picrotoxin-induced (PCT) convulsion models in mice. D ...
DOI:
10.1016/j.jep.2011.09.043
PubMed:
22004892

4. Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips

Author:
Guo, Dejian; Xu, Lijia; Cao, Xinwei; Guo, Yuqing; Ye, Yan; Chan, Chi-On; Mok, Daniel K.W.; Yu, Zhiling; Chen, Sibao
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 717-722
ISSN:
0378-8741
Subject:
Rosa multiflora; acetates; animal models; anti-inflammatory activity; dietary supplements; ears; edema; ethers; gene expression; granuloma; herbal medicines; herbs; inflammation; ingredients; mechanism of action; messenger RNA; mice; nitric oxide; nitric oxide synthase; oral administration; rats; unsaturated fatty acids
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The hip of Rosa multiflora Thunb. has been traditionally used as a dietary supplement and a herbal remedy for the treatment of various diseases including cold, flu, inflammation, osteoarthritis, rheumatoid arthritis and chronic pain in China. AIMS OF THE STUDY: To explore the anti-inflammatory ingredient of the hip of R. multiflora Thunb. and its mechanism of action ...
DOI:
10.1016/j.jep.2011.10.010
PubMed:
22019508

5. Anti-inflammatory and anti-nociceptive activities of ethanolic extract and its various fractions from Adiantum capillus veneris Linn.

Author:
Haider, Saqlain; Nazreen, Syed; Alam, Mohammad Mahboob; Gupta, Amit; Hamid, Hinna; Alam, Mohammad Sarwar
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 741-747
ISSN:
0378-8741
Subject:
Adiantum; acetates; analgesic effect; anti-inflammatory activity; anti-ulcer activity; body weight; carrageenan; edema; histopathology; ibuprofen; indomethacin
Abstract:
... AIM OF THE STUDY: To investigate the anti-inflammatory and anti-nociceptive activities of the crude ethanolic extract of Adiantum capillus veneris Linn. (Adiantaceae) and its various fractions. MATERIALS AND METHODS: The ethanolic extract and its fractions were given at a dose of 200mg/kg po and 300mg/kg po for testing their anti-inflammatory activity by carrageenan induced hind paw edema. The ana ...
DOI:
10.1016/j.jep.2011.10.012
PubMed:
22020277

6. Are there new therapeutic options for treating lung cancer based on herbal medicines and their metabolites?

Author:
Jeong, Soo-Jin; Koh, Wonil; Kim, Bonglee; Kim, Sung-Hoon
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 652-661
ISSN:
0378-8741
Subject:
drug therapy; lung neoplasms; phytochemicals; multiple drug resistance; adverse effects; metabolites; metastasis; mortality; patients; quality of life; databases; angiogenesis; herbal medicines; quality control
Abstract:
... ETHONOPHARMACOLOGICAL RELEVANCE: Lung cancer is one of the most lethal cancers in terms of mortality and incidence worldwide. Despite intensive research and investigation, treatment of lung cancer is still unsatisfactory due to adverse effects and multidrug resistance. Recently, herbal drugs have been recognized as one of attractive approaches for lung cancer therapy with little side effects. Furt ...
DOI:
10.1016/j.jep.2011.10.018
PubMed:
22032843

7. Effect of Morus nigra aqueous extract treatment on the maternal–fetal outcome, oxidative stress status and lipid profile of streptozotocin-induced diabetic rats

Author:
Volpato, G.T.; Calderon, I.M.P.; Sinzato, S.; Campos, K.E.; Rudge, M.V.C.; Damasceno, D.C.
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 691-696
ISSN:
0378-8741
Subject:
Morus nigra; antioxidant activity; blood sampling; cholesterol; diabetes; fetus; hyperglycemia; leaf extracts; mulberries; oxidative stress; pregnancy; progeny; rats; streptozotocin; traditional medicine; triacylglycerols; very low density lipoprotein; virgin females
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Morus nigra, commonly known as black mulberry, is widely used in Brazilian folk medicine for the diabetes treatment. AIM OF THIS STUDY: To evaluate the effect of Morus nigra aqueous extract treatment on maternal lipid and oxidative stress profile, reproductive outcomes, and also fetal anomaly incidence from diabetic and non-diabetic rats. MATERIALS AND METHODS: Diab ...
DOI:
10.1016/j.jep.2011.09.044
PubMed:
21986227

8. Effects of puerarin on expression of cardiac Smad3 and Smad7 mRNA in spontaneously hypertensive rat

Author:
Zhang, Nian-Bao; Huang, Zheng-Gui; Cui, Wei-Dong; Ding, Bo-Ping
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 737-740
ISSN:
0378-8741
Subject:
Pueraria montana var. lobata; gene expression; hypertension; messenger RNA; myocardium; protective effect; rats; roots; traditional medicine; transforming growth factors
Abstract:
... AIM OF THE STUDY: Puerarin is a pure extract from traditional Chinese medicine Kudzu root. It has been used to treat hypertension and angina pectoris. In our previous study, it showed a protective effect against cardiac hypertrophy in rats. This study was to observe effects of puerarin on expression of cardiac transforming growth factor β₁ (TGF-β₁), Smad3 and Smad7 mRNA in the spontaneously hypert ...
DOI:
10.1016/j.jep.2011.10.013
PubMed:
22027447

9. Eupatorium perfoliatum L.: Phytochemistry, traditional use and current applications

Author:
Hensel, Andreas; Maas, Mareike; Sendker, Jandirk; Lechtenberg, Matthias; Petereit, Frank; Deters, Alexandra; Schmidt, Thomas; Stark, Timo
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 641-651
ISSN:
0378-8741
Subject:
Eupatorium; Plasmodium falciparum; analytical methods; anti-inflammatory activity; antioxidant activity; caffeic acid; control methods; fever; flavonoids; in vitro studies; plant extracts; polysaccharides; quality control; sesquiterpenoid lactones; surveys; tannins; North America
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Eupatorium perfoliatum L. originates from North America, where it has been widely used since centuries by native Indians. Additionally extracts are used also in Europe as immunostimulating agent for treatment of fever and cold. The following review summarizes published data on phytochemistry, ethnopharmacological use, as well as clinical and preclinical data. MATERI ...
DOI:
10.1016/j.jep.2011.10.002
PubMed:
22004891

10. Evaluation of antihyperglycemic activity of Cocos nucifera Linn. on streptozotocin induced type 2 diabetic rats

Author:
Naskar, Sagar; Mazumder, Upal K.; Pramanik, Goutam; Gupta, Malaya; Suresh Kumar, R.B.; Bala, Asis; Islam, Aminul
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 769-773
ISSN:
0378-8741
Subject:
Cocos nucifera; adverse effects; antioxidants; biomarkers; blood glucose; cardioprotective effect; cholesterol; coconuts; diabetes; diarrhea; glibenclamide; hypoglycemic agents; inflorescences; juices; lipid peroxidation; rats; streptozotocin; sugars; superoxide dismutase; triacylglycerols
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The plant Cocos nucifera Linn. (Arecaceae) is commonly known as coconut. Traditionally the juice of the young spadix when fresh is used in diarrhea and diabetes. The objective of the present study was to investigate the effect of antidiabetic activity and effect on lipid profile as well as cardioprotective effect of hydro-methanol extract of Cocos nucifera (HECN) on ...
DOI:
10.1016/j.jep.2011.10.021
PubMed:
22041106

11. Gastrointestial and respiratory activities of Acacia leucophloea

Author:
Imran, Imran; Hussain, Liaqat; Zia-Ul-Haq, M.; Janbaz, Khalid Hussain; Gilani, Anwar H.; De Feo, Vincenzo
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 676-682
ISSN:
0378-8741
Subject:
Acacia leucophloea; anthelmintics; antidiarrheal effect; antidotes; asthma; bark; bronchitis; carbachol; castor oil; cough; dental caries; dysentery; fever; guinea pigs; hemorrhage; ileum; in vitro studies; in vivo studies; jejunum; mechanism of action; methanol; mice; plant extracts; protective effect; rabbits; skin diseases; snake bites; traditional medicine; vomiting; Pakistan
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The barks of Acacia leucophloea (Fabaceae) are used in Pakistan traditional medicine as an astringent, a bitter, a thermogenic, a styptic, a preventive of infections, an anthelmintic, a vulnery, a demulcent, an expectorant, an antipyretic, an antidote for snake bites and in the treatment of bronchitis, cough, vomiting, wounds, ulcers, diarrhea, dysentery, internal a ...
DOI:
10.1016/j.jep.2011.09.019
PubMed:
21959184

12. Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats

Author:
Feng, Yibin; Wang, Ning; Ye, Xingshen; Li, Huangyun; Feng, Yigang; Cheung, Fan; Nagamatsu, Tadashi
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 683-690
ISSN:
0378-8741
Subject:
alanine transaminase; antioxidant activity; aspartate transaminase; carbon; carbon tetrachloride; chronic diseases; hepatoprotective effect; hepatotoxicity; liver; liver diseases; medicine; microscopy; models; observational studies; oxidative stress; oxides; rats; superoxide dismutase
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Coptidis rhizoma is traditionally used for heat-clearing and toxic-scavenging and it belongs to liver meridian in Chinese medicine practice. Clinically, Coptidis rhizoma can be used for hepatic and biliary disorders, yet details in the therapies of liver diseases and underlying mechanism(s) remain unclear. Our previous study demonstrated that Coptidis rhizoma aqueou ...
DOI:
10.1016/j.jep.2011.09.032
PubMed:
21963555

13. Immunomodulatory properties of Xylaria nigripes in peritoneal macrophage cells of Balb/c mice

Author:
Ko, Huey-Jiun; Song, Airong; Lai, Min-Nan; Ng, Lean-Teik
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 762-768
ISSN:
0378-8741
Subject:
RNA; Xylaria nigripes; anti-inflammatory activity; cytotoxicity; ethanol; fungi; lipopolysaccharides; macrophages; mechanism of action; mice; nitrites; oxides; phenol; phosphorylation; prostaglandins; traditional medicine; viability
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Wu Ling Shen, a folklore name for Xylaria nigripes (XN), is a high value medicinal fungus used in traditional Chinese medicine. AIM OF STUDY: The present study aimed to examine the immunomodulatory properties of aqueous (XN-H) and ethanol (XN-E) XN extracts in lipopolysaccharide (LPS)-induced peritoneal macrophage cells of Balb/c mice. MATERIALS AND METHODS: After t ...
DOI:
10.1016/j.jep.2011.10.022
PubMed:
22044578

14. In vitro chemo-preventative activity of Crotalaria agatiflora subspecies agatiflora Schweinf

Author:
Le Roux, Karlien; Hussein, Ahmed A.; Lall, Namrita
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 748-755
ISSN:
0378-8741
Subject:
Crotalaria; antioxidant activity; bacterial infections; bioassays; cytotoxicity; ethanol; flow cytometry; fractionation; iodides; leaf extracts; light microscopy; mechanism of action; medicinal plants; medicinal properties; necrosis; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Crotalaria species have been widely used in Chinese traditional medicine to treat several types of internal cancers. Crotalaria agatiflora is used as a medicinal plant in several African countries for the treatment of bacterial and viral infections as well as for cancer. MATERIALS AND METHODS: Water and ethanol extracts of the leaves of Crotalaria agatiflora were ev ...
DOI:
10.1016/j.jep.2011.10.011
PubMed:
22041105

15. Iridoids as chemical markers of false ipecac (Ronabea emetica), a previously confused medicinal plant

Author:
Berger, Andreas; Fasshuber, Hannes; Schinnerl, Johann; Robien, Wolfgang; Brecker, Lothar; Valant-Vetschera, Karin
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 756-761
ISSN:
0378-8741
Subject:
Carapichea ipecacuanha; Psychotria; acids; additives; adulterated products; drugs; fruits; high performance liquid chromatography; indole alkaloids; iridoids; leaves; mass spectrometry; medicinal plants; nuclear magnetic resonance spectroscopy; rhizomes; roots; traditional medicine; Colombia; Panama
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Several roots or rhizomes of rubiaceous species are reportedly used as the emetic and antiamoebic drug ipecac. True ipecac (Carapichea ipecacuanha) is chemically well characterized, in contrast to striated or false ipecac derived from the rhizomes of Ronabea emetica (syn. Psychotria emetica). Besides its previous use as substitute of ipecac, the latter species is ap ...
DOI:
10.1016/j.jep.2011.10.024
PubMed:
22041104

16. Khat (Catha edulis) alters the phenotype and anti-microbial activity of peripheral blood mononuclear cells

Author:
Murdoch, Craig; Aziz, Hesham Abdul; Fang, Hsin-Yu; Jezan, Hussun; Musaid, Raga; Muthana, Munitta
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 780-787
ISSN:
0378-8741
Subject:
Catha edulis; apoptosis; bacteria; cytokines; cytotoxicity; dextran; epithelial cells; gene expression regulation; mastication; mitogen-activated protein kinase; monitoring; mononuclear leukocytes; mouth diseases; phenotype; reactive oxygen species; receptors; risk; secretion; transcription factors
Abstract:
... AIMS OF STUDY: The habit of khat chewing has been associated with increased risk of systemic and oral disease. Although research has been conducted on the affects of khat on oral epithelial cells, little is known about its influence on immune cells. This study examined the biological effects of khat on the phenotype and function of peripheral blood mononuclear cells (PBMCs). MATERIAL AND METHODS: ...
DOI:
10.1016/j.jep.2011.10.030
PubMed:
22063724

17. Neuroprotective effects of a traditional herbal prescription on transient cerebral global ischemia in gerbils

Author:
Cai, Mudan; Shin, Bum Young; Kim, Dong Hyun; Kim, Jong Min; Park, Se Jin; Park, Chan Sung; Won, Do Hee; Hong, Nam Doo; Kang, Dong Hyo; Yutaka, Yamamoto; Ryu, Jong Hoon
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 723-730
ISSN:
0378-8741
Subject:
gerbils; memory; ischemia; anti-inflammatory activity; neuroprotective effect; dementia; immunohistochemistry; Lycium chinense; mice; Panax ginseng; brain damage; oral administration; carotid arteries; Wolfiporia cocos; honey; Rehmannia glutinosa
Abstract:
... AIM OF THE STUDY: Kyung-Ok-Ko (KOK), a traditional herbal prescription composed of Rehmannia glutinosa var. purpurae, Panax ginseng, Poria cocos, Lycium chinense, Aquillaria agallocha and honey, has been used to treat age-related symptoms, such as amnesia or dementia, and has been shown to ameliorate scopolamine-induced memory impairment in mice. However, the effects of KOK on transient cerebral g ...
DOI:
10.1016/j.jep.2011.10.016
PubMed:
22020275

18. Novel use patterns of Salvia divinorum: Unobtrusive observation using YouTube™

Author:
Casselman, Ivan; Heinrich, Michael
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 662-667
ISSN:
0378-8741
Subject:
sage; humans; Salvia; methodology; world wide web; researchers; Mexico
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE AND AIMS: The traditional use of the Hallucinogenic sage, Salvia divinorum has been of ethnopharmalogical interest for some time. This plant, endemic to Oaxaca Mexico and traditionally used by the Mazatec, is now utilized worldwide for its psychoactive effects. This use demonstrates a novel use pattern which is distinctly different from Mazatec use. This study offers ...
DOI:
10.1016/j.jep.2011.07.065
PubMed:
21843613

19. Preliminary study of antidiabetic activity of the methanolic leaf extract of Axonopus compressus (P. Beauv) in alloxan-induced diabetic rats

Author:
Ibeh, Bartholomew O.; Ezeaja, Maxwell I.
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 713-716
ISSN:
0378-8741
Subject:
Axonopus; alloxan; blood; blood glucose; cold; diabetes; glibenclamide; glucose; leaf extracts; people; rats; reference standards; tail; Nigeria
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Axonopus Compressus is commonly used by the people of Southern Nigeria to treat different ailment such as common cold and diabetes. This study therefore, evaluated the anti-diabetic effect of the methanolic leaf extract of the plant. MATERIALS AND METHODS: Diabetes was induced in the rats by intraperitoneal (i.p.) injection of alloxan monohydrate at the dose of 180m ...
DOI:
10.1016/j.jep.2011.10.009
PubMed:
22032842

20. Protective effect of hexane extracts of Uncaria sinensis against photothrombotic ischemic injury in mice

Author:
Park, Sun Haeng; Kim, Ji Hyun; Park, Se Jin; Bae, Sun Sik; Choi, Young Whan; Hong, Jin Woo; Choi, Byung Tae; Shin, Hwa Kyoung
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 774-779
ISSN:
0378-8741
Subject:
Uncaria sinensis; acetates; aorta; brain; edema; herbal medicines; hexane; infarction; ischemia; mechanism of action; methanol; mice; nitric oxide synthase; phosphorylation; protective effect; stroke; therapeutics; traditional medicine; vasodilation; United States
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Uncaria sinensis (US) has been used in traditional Korean medicine to treat vascular disease and to relieve various neurological symptoms. AIM OF THE STUDY: Scientific evidence related to the effectiveness or action mechanism of US on cerebrovascular disease has not been examined experimentally. Here, we investigated the cerebrovascular protective effect of US extra ...
DOI:
10.1016/j.jep.2011.10.026
PubMed:
22051882

21. Protective effect of Icariin on the early stage of experimental diabetic nephropathy induced by streptozotocin via modulating transforming growth factor β₁ and type IV collagen expression in rats

Author:
Qi, Min-You; Kai-Chen,; Liu, Hao-Ran; Su, Yan-hui; Yu, Su-Qing
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 731-736
ISSN:
0378-8741
Subject:
Western blotting; blood; blood glucose; collagen; creatinine; diabetic nephropathy; immunohistochemistry; kidneys; light microscopy; malondialdehyde; protective effect; rats; streptozotocin; superoxide dismutase; traditional medicine; transforming growth factors; urea nitrogen
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Icariin is a major constituent of flavonoid isolated from the plant Herba epimedii, which is used as a traditional Chinese medicine to nourish the kidney and reinforce yang. Therefore, the pharmacological studied of its diabetic nephropathy effect was undertaken to validate its traditional use. MATERIALS AND METHODS: Diabetes was induced in male Sprague–Dawley rats ...
DOI:
10.1016/j.jep.2011.10.015
PubMed:
22027446

22. Screening of a polar extract of Paeonia rockii: Composition and antioxidant and antifungal activities

Author:
Picerno, Patrizia; Mencherini, Teresa; Sansone, Francesca; Del Gaudio, Pasquale; Granata, Ilaria; Porta, Amalia; Aquino, Rita P.
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 705-712
ISSN:
0378-8741
Subject:
Candida albicans; Paeonia; antifungal properties; antioxidant activity; drugs; free radicals; gallic acid; monoterpenoids; nuclear magnetic resonance spectroscopy; polyphenols; reversed-phase high performance liquid chromatography; roots; screening; solvents; taxifolin; traditional medicine; triterpenoids
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The genus Paeonia (Paeoniaceae), is one of the most important source of crude drugs in traditional Chinese medicine and investigation on many species is large. Up to now studies on Paeonia rockii, one of the eight species recognized in the section Moutan, are very limited. AIM OF THE STUDY: This research aimed to investigate the composition of Paeonia rockii roots a ...
DOI:
10.1016/j.jep.2011.09.056
PubMed:
22004890

23. Transcriptional profiling of human skin fibroblast cell line Hs27 induced by herbal formula Astragali Radix and Rehmanniae Radix

Author:
Zhang, Qi; Wei, Fan; Fong, Chi Chun; Yu, Wai Kin; Chen, Yao; Koon, Chi Man; Lau, Kit Man; Leung, Ping Chung; Lau, Clara Bik San; Fung, Kwok Pui; Yang, Mengsu
Source:
Journal of ethnopharmacology 2011 v.138 no.3 pp. 668-675
ISSN:
0378-8741
Subject:
angiogenesis; cell cycle; cell proliferation; complementary DNA; extracellular matrix; fibroblasts; gene expression; genes; herbs; humans; inflammation; insulin resistance; microarray technology; rats; tissue repair; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The herbs Astragali Radix (AR) and Rehmanniae Radix (RR) have long been used in traditional Chinese Medicine and serve as the principal herbs in treating diabetic foot ulcer. AIM OF THE STUDY: Chinese herbal formulus comprising Astragali Radix (AR) and Rehmanniae Radix (RR) have been shown to improve the healing of diabetic foot ulcer through enhancing the viability ...
DOI:
10.1016/j.jep.2011.08.080
PubMed:
22075453

24. Acalypha wilkesiana extracts induce apoptosis by causing single strand and double strand DNA breaks

Author:
Lim, S.W.; Ting, K.N.; Bradshaw, T.D.; Zeenathul, N.A.; Wiart, C.; Khoo, T.J.; Lim, K.H.; Loh, H.S.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 616-623
ISSN:
0378-8741
Subject:
Acalypha wilkesiana; DNA; DNA damage; acetates; apoptosis; brain damage; breast neoplasms; carcinoma; cytotoxicity; ethanol; gel electrophoresis; hexane; humans; inflammation; lung neoplasms; lungs; natural resources; necrosis; new drugs; patients; plant extracts; powders; researchers; seeds; viability; Nigeria
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The seeds of Acalypha wilkesiana have been used empirically by traditional healers in Southwest Nigeria together with other plants as a powder mixture to treat patients with breast tumours and inflammation. AIM OF THE STUDY: There is an increasing interest among researchers in searching for new anticancer drugs from natural resources, particularly plants. This study ...
DOI:
10.1016/j.jep.2011.10.005
PubMed:
22008878

25. Acute and subchronic oral toxicity assessment of the herbal formula Kai-Xin-San

Author:
Mu, Li-Hua; Huang, Zhi-Xiong; Liu, Ping; Hu, Yuan; Gao, Yue
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 351-357
ISSN:
0378-8741
Subject:
Alzheimer disease; acute toxicity; alkaline phosphatase; blood glucose; body weight changes; food consumption; lethal dose 50; lymphocytes; mice; no observed adverse effect level; oral administration; rats; subchronic toxicity; tissue weight; toxicity testing; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Kai-Xin-San (KXS) is a famous traditional Chinese medicine (TCM) formula. It has been used in the treatment of diseases including neurasthenia, Alzheimer's disease and neurosis. AIM OF THE STUDY: To provide information on the potential toxicity of KXS, we evaluated the acute and subchronic toxicity in rodents. MATERIALS AND METHODS: In acute study, a single administ ...
DOI:
10.1016/j.jep.2011.08.033
PubMed:
21884776

26. Agrimonia pilosa ethanol extract induces apoptotic cell death in HepG2 cells

Author:
Nho, Kyoung Jin; Chun, Jin Mi; Kim, Ho Kyoung
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 358-363
ISSN:
0378-8741
Subject:
Agrimonia; Western blotting; apoptosis; caspase-3; caspase-8; caspase-9; cell cycle; cell proliferation; ethanol; neoplasms; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Agrimonia pilosa (AP) has been used as a traditional herbal medicine for treating various cancers and diseases in Asian countries. MATERIALS AND METHODS: Cell viability along with caspase-3/-7, caspase-8 and caspase-9 activity were measured to detect apoptosis. The activity of the apoptotic factors bcl-2, bcl-xl, mcl-1, XIAP, BID, BIK, caspase-3, caspase-9 and PARP ...
DOI:
10.1016/j.jep.2011.09.008
PubMed:
21945237

27. An ethnobotanical survey of medicinal plants used in the Siwai and Buin districts of the Autonomous Region of Bougainville

Author:
Waruruai, Julie; Sipana, Beulah; Koch, Michael; Barrows, Louis R.; Matainaho, Teatulohi K.; Rai, Prem P.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 564-577
ISSN:
0378-8741
Subject:
World Health Organization; developing countries; islands; languages; medicinal plants; multicultural diversity; plant health; questionnaires; rural health care; surveys; traditions; universities; university programs; Papua New Guinea
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Traditional knowledge of medicinal plant use in many regions of Papua New Guinea and the Autonomous Region of Bougainville is poorly described and rapidly disappearing. A program initiated by the University of Papua New Guinea to systematically document and preserve traditional knowledge of medicinal plant use was initiated with WHO help in 2001. AIM OF THE STUDY: T ...
DOI:
10.1016/j.jep.2011.09.052
PubMed:
22004894
PubMed Central:
PMC3245962

28. An ethnobotany of Western Cape Rasta bush medicine

Author:
Aston Philander, Lisa
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 578-594
ISSN:
0378-8741
Subject:
Apiaceae; Asteraceae; Euphorbiaceae; Fabaceae; Lamiaceae; Rutaceae; cardiovascular diseases; ethnobotany; herbs; invasive species; inventories; leaves; medicinal plants; medicine; multicultural diversity; physicians; type collections; South Africa
Abstract:
... AIMS OF THIS STUDY: This descriptive ethnobiological research is the first documentation of the materials utilized in the pharmacopeia of a novel group of herbalists, Rasta bush doctors, found in the botanically diverse Western Cape of South Africa. This article suggests that medicinal plants used by bush doctors unite the disparate ethnomedicines found in South Africa. MATERIALS AND METHODS: Ethn ...
DOI:
10.1016/j.jep.2011.10.004
PubMed:
22004893

29. An inventory of the ethnobotanicals used as anti-diabetic by a rural community of Dhemaji district of Assam, Northeast India

Author:
Tarak, Doi; Namsa, Nima D.; Tangjang, Sumpam; Arya, S.C.; Rajbonshi, Bhaskar; Samal, P.K.; Mandal, M.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 345-350
ISSN:
0378-8741
Subject:
Amomum; Cinnamomum; Colocasia esculenta; Dillenia; Euphorbia; Garcinia; Ligularia; Solanum anguivi; Sterculia; Tabernaemontana divaricata; diabetes mellitus; households; indigenous knowledge; interviews; medicinal plants; people; questionnaires; rural communities; rural health care; surveys; India
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Traditional remedies used for treating diabetic ailments are very important in the primary health care of the people living in rural Dhemaji district of Assam, north-east India. Novel information gathered from the current survey is important in preserving folk indigenous knowledge. MATERIALS AND METHODS: Interviews were conducted amongst 80 households comprising of ...
DOI:
10.1016/j.jep.2011.08.018
PubMed:
21871548

30. Anti-inflammatory activity of an ethanolic Caesalpinia sappan extract in human chondrocytes and macrophages

Author:
Wu, Shengqian Q.; Otero, Miguel; Unger, Frank M.; Goldring, Mary B.; Phrutivorapongkul, Ampai; Chiari, Catharina; Kolb, Alexander; Viernstein, Helmut; Toegel, Stefan
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 364-372
ISSN:
0378-8741
Subject:
Caesalpinia sappan; anti-inflammatory activity; cartilage; chondrocytes; enzyme-linked immunosorbent assay; extracellular matrix; gene expression; humans; inflammation; lipopolysaccharides; luciferase; macrophages; messenger RNA; models; nitric oxide; nitric oxide synthase; osteoarthritis; patients; polymerase chain reaction; traditional medicine; transcriptional activation; tumor necrosis factor-alpha; viability
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Caesalpinia sappan is a common remedy in Traditional Chinese Medicine and possesses diverse biological activities including anti-inflammatory properties. Osteoarthritis (OA) is a degenerative joint disease with an inflammatory component that drives the degradation of cartilage extracellular matrix. In order to provide a scientific basis for the applicability of Caes ...
DOI:
10.1016/j.jep.2011.09.011
PubMed:
21963554
PubMed Central:
PMC3282169

31. Anti-inflammatory effect of extract and fractions from the leaves of Byrsonima intermedia A. Juss. in rats

Author:
Moreira, Lucimara Q.; Vilela, Fabiana C.; Orlandi, Lidiane; Dias, Danielle F.; Santos, Ana Laura A.; da Silva, Marcelo A.; Paiva, Renato; Alves-da-Silva, Geraldo; Giusti-Paiva, Alexandre
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 610-615
ISSN:
0378-8741
Subject:
Byrsonima; acetates; animal models; anti-inflammatory activity; catechin; dysentery; edema; high performance liquid chromatography; inflammation; leaves; pellets; phenolic compounds; rats; traditional medicine
Abstract:
... AIM OF THE STUDY: Byrsonima intermedia is commonly used for its antiseptic, antimicrobial, and anti-inflammatory properties in the treatment of diarrhea and dysentery in Brazilian folk medicine. The purpose of this study was to examine the anti-inflammatory activity of the aqueous extract and fractions of Byrsonima intermedia leaves. MATERIALS AND METHODS: Rats with carrageenan-induced paw edema a ...
DOI:
10.1016/j.jep.2011.10.006
PubMed:
22008877

32. Aqueous fraction from Costus spiralis (Jacq.) Roscoe leaf reduces contractility by impairing the calcium inward current in the mammalian myocardium

Author:
Britto, Raquel Moreira; Santos, André Luiz; Cruz, Jader Santos; Gondim, Antonio Nei Santana; Lauton-Santos, Sandra; Lara, Aline; Guatimosim, Silvia; Vasconcelos, Carla Maria Lins; Estevam, Charles dos Santos; Dias, Antonio Santos; Oliveira, Evaleide Diniz; Lima, Adriana Karla; Souza, Rejane Cardoso; Conde-Garcia, Eduardo Antonio
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 382-389
ISSN:
0378-8741
Subject:
Costus; acetates; atropine; calcium; calcium chloride; chloroform; flavonols; fluorescence; fluorescence microscopy; guinea pigs; hypertension; leaves; mechanism of action; mice; myocardium; phenols; potassium; sodium; tannins; traditional medicine; xanthones
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Brazilian folk medicine uses infusion of Costus spiralis leaf to help people to treat arterial hypertension and syndromes of cardiac hyperexcitability. AIM OF THE STUDY: Evaluate the aqueous fraction (AqF) effect on atrial contractility and investigate its mechanism of action. MATERIALS AND METHODS: The AqF effect on the cardiac contractility was studied on isolated ...
DOI:
10.1016/j.jep.2011.09.013
PubMed:
21963557

33. A traditional Chinese herbal preparation, Er-Zhi-Wan, prevent ovariectomy-induced osteoporosis in rats

Author:
Cheng, Min; Wang, Qingwei; Fan, Yinke; Liu, Xueying; Wang, Lu; Xie, Renmin; Ho, Charlene C.; Sun, Wenji
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 279-285
ISSN:
0378-8741
Subject:
alkaline phosphatase; alternative medicine; bone density; bone resorption; calcium; estradiol; femur; kidney diseases; kidneys; oral administration; osteocalcin; osteoporosis; phosphorus; rats; tibia; urine; uterus; vertebrae; weight gain
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Er-Zhi-Wan (EZW), a classic Chinese formulation, which contains Fructus Ligustri Lucidi (FLL) and Herba Ecliptae (HE). EZW is widely used to prevent and treat various kidney diseases for its actions of nourishing the kidney and strengthening tendon and bone. Although recent reports indicate that EZW restrains osteoclastic bone resorption, its effects on the protecti ...
DOI:
10.1016/j.jep.2011.09.030
PubMed:
22001072

34. Baicalein, isolated from Scutellaria baicalensis, protects against endothelin-1-induced pulmonary artery smooth muscle cell proliferation via inhibition of TRPC1 channel expression

Author:
Lin, Yi-Ling; Lin, Rong-Jyh; Shen, Kuo-Pyng; Dai, Zen-Kong; Chen, Ing-Jun; Wu, Jiunn-Ren; Wu, Bin-Nan
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 373-381
ISSN:
0378-8741
Subject:
Scutellaria baicalensis; Western blotting; calcium; cell culture; cell proliferation; flow cytometry; interphase; membrane proteins; myocytes; protein kinase C; protein synthesis; pulmonary artery; rats; receptors; smooth muscle
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: We investigated the antiproliferative effects of baicalein, isolated from Scutellaria baicalensis (Huang-qin), on ET-1-mediated pulmonary artery smooth muscle cells (PASMCs) proliferation and the mechanisms underlying these effects. MATERIALS AND METHODS: Intrapulmonary artery smooth muscle cells were isolated and cultured from female Sprague-Dawley rats and used du ...
DOI:
10.1016/j.jep.2011.09.014
PubMed:
21963569

35. Biomarkers in the early period of acute myocardial infarction in rat serum and protective effects of Shexiang Baoxin Pill using a metabolomic method

Author:
Jiang, Peng; Dai, Weixing; Yan, Shikai; Chen, Zhongliang; Xu, Ruilin; Ding, Jianmi; Xiang, Li; Wang, Shuping; Liu, Runhui; Zhang, Weidong
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 530-536
ISSN:
0378-8741
Subject:
acids; aldosterone; biomarkers; biosynthesis; corticosterone; cortisol; cystathionine; desoxycorticosterone; epinephrine; hypertrophy; inflammation; mass spectrometry; myocardial infarction; protective effect; rats; reversed-phase liquid chromatography; steroid hormones; thymidine; traditional medicine; uric acid
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: To identify the biomarkers in early period of acute myocardial infarction (AMI) in rat serum and reveal the effective mechanism of a Traditional Chinese Medicine (TCM) named Shexiang Baoxin Pill (SBP). MATERIAL AND METHOD: A metabolomic approach using reversed-phase liquid chromatography/quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS) was developed. RESULT ...
DOI:
10.1016/j.jep.2011.09.049
PubMed:
22001859

36. Black cohosh (Cimicifuga racemosa) relaxes the isolated rat thoracic aorta through endothelium-dependent and -independent mechanisms

Author:
Kim, Eun-Young; Lee, Young Joo; Rhyu, Mee-Ra
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 537-542
ISSN:
0378-8741
Subject:
Actaea racemosa; agonists; aorta; calcium; cyclic GMP; endothelium; mechanism of action; methylene blue; norepinephrine; potassium channels; rats; receptors; rhizomes; serotonin; vasodilation; Europe; North America
Abstract:
... AIM OF THE STUDY: The rhizome of the Cimicifuga racemosa (commonly known as black cohosh) has been used in treatment of climacteric complaints for decades in North America and Europe. A number of studies investigated the estrogenic potential of black cohosh, but its effectiveness is still controversial. Recently, it was reported that the extract of black cohosh acted as an agonist at the serotonin ...
DOI:
10.1016/j.jep.2011.09.048
PubMed:
22001858

37. Brazilian green propolis and its constituent, Artepillin C inhibits allogeneic activated human CD4 T cells expansion and activation

Author:
Cheung, Ka-Wai; Sze, Daniel Man-Yuen; Chan, Wing Keung; Deng, Rui-Xia; Tu, Wenwei; Chan, Godfrey Chi-Fung
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 463-471
ISSN:
0378-8741
Subject:
mechanism of action; traditional medicine; human cell lines; humans; T-lymphocytes; interferon-gamma; cytotoxicity; hosts; interleukins; enzyme-linked immunosorbent assay; propolis; cell proliferation; apoptosis
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Propolis has long been used as a popular folk medicine by various ethnic groups due to its wide spectrum of alleged biological and pharmaceutical properties including anti-microbial, anti-cancer and anti-inflammatory functions. All these can be linked to the modulation of immune function. Therefore, it will be relevant for us to find out whether there is any novel c ...
DOI:
10.1016/j.jep.2011.09.031
PubMed:
21964192

38. Chemical composition, antinociceptive and anti-inflammatory effects in rodents of the essential oil of Peperomia serpens (Sw.) Loud

Author:
Pinheiro, B.G.; Silva, A.S.B.; Souza, G.E.P.; Figueiredo, J.G.; Cunha, F.Q.; Lahlou, S.; da Silva, J.K.R.; Maia, J.G.S.; Sousa, P.J.C.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 479-486
ISSN:
0378-8741
Subject:
Peperomia; acetic acid; adhesion; analgesic effect; anti-inflammatory activity; asthma; carrageenan; cell movement; chemical composition; dextran; ears; edema; essential oils; formalin; gas chromatography; inflammation; leaves; leukocytes; mass spectrometry; mice; models; nociception; pain; rats; rolling; traditional medicine; trees; Amazonia
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Peperomia serpens (Piperaceae), popularly known as “carrapatinho”, is an epiphyte herbaceous liana grown wild on different host trees in the Amazon rainforest. Its leaves are largely used in Brazilian folk medicine to treat inflammation, pain and asthma. AIM OF THE STUDY: This study investigated the effects of essential oil of Peperomia serpens (EOPs) in standard ro ...
DOI:
10.1016/j.jep.2011.09.037
PubMed:
21971207

39. Detection of antifungal compounds in Polygonum ferrugineum Wedd. extracts by bioassay-guided fractionation. Some evidences of their mode of action

Author:
López, S.N.; Furlan, R.L.E.; Zacchino, S.A.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 633-636
ISSN:
0378-8741
Subject:
Epidermophyton floccosum; Neurospora crassa; Polygonum; aerial parts; agar; antibiotics; antifungal agents; antifungal properties; chalcone; fractionation; fungi; hyphae; mechanism of action; scanning electron microscopy; tissue repair; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Polygonum ferrugineum Wedd. (Polygonaceae) is used to heal infected wounds and as antiseptic, antibiotic or antifungal in the traditional Argentinean medicine. The present investigation was carried out to evaluate the antifungal properties of different extracts of aerial parts of Polygonum ferrugineum, in order to give support to its ethnopharmacological use and to ...
DOI:
10.1016/j.jep.2011.09.038
PubMed:
22001591

40. Double directional adjusting estrogenic effect of naringin from Rhizoma drynariae (Gusuibu)

Author:
Guo, Dongyan; Wang, Junzhi; Wang, Xingqin; Luo, Huajun; Zhang, Hongqi; Cao, Dan; Chen, Lei; Huang, Nianyu
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 451-457
ISSN:
0378-8741
Subject:
active ingredients; agitation; amino acids; antagonists; binding capacity; binding sites; bones; cell proliferation; computers; drugs; estradiol; estrogenic properties; hydrogen bonding; mice; naringenin; naringin; osteoporosis; oxygen; receptors; traditional medicine; uterus; weight gain; yeasts
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Chinese traditional medicine Rhizoma drynariae (Gusuibu) is widely used for clinically treating osteoporosis and bone non-union. Naringin and its active metabolite naringenin are the main active ingredients of Rhizoma drynariae total flavonoids. AIM OF THE STUDY: The purpose of this paper is to confirm estrogenic and anti-estrogenic activity of naringin and naringen ...
DOI:
10.1016/j.jep.2011.09.034
PubMed:
21964193

41. Effectiveness of Vernonia scorpioides ethanolic extract against skin inflammatory processes

Author:
Rauh, Laryssa K.; Horinouchi, Cíntia D.S.; Loddi, Alliete M.V.; Pietrovski, Evelise F.; Neris, Rosalina; Souza-Fonseca-Guimarães, Fernando; Buchi, Dorly F.; Biavatti, Maique W.; Otuki, Michel F.; Cabrini, Daniela A.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 390-397
ISSN:
0378-8741
Subject:
Vernonia; acetates; anti-inflammatory activity; anti-inflammatory agents; arachidonic acid; ears; edema; histology; hypersensitivity; inflammation; medicinal plants; mice; models; skin diseases; topical application
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Vernonia scorpioides (Asteraceae) is a native Brazilian medicinal plant that is commonly used to treat skin disorders. Considering the traditional use of Vernonia scorpioides and the lack of information about its pharmacological properties, we investigated the topical anti-inflammatory effect of the ethanolic extract of Vernonia scorpioides (EEVS) on acute and chron ...
DOI:
10.1016/j.jep.2011.09.012
PubMed:
21959183

42. Effects of Cistanche deserticola on behavior and signs of cataract and retinopathy in senescence-accelerated OXYS rats

Author:
Stefanova, Natalia A.; Fursova, Anzhela Zh.; Sarsenbaev, Kanat N.; Kolosova, Nataliya G.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 624-632
ISSN:
0378-8741
Subject:
Cistanche; Oxalis; animal behavior; anxiety; body weight; cataract; decline; homeostasis; medicine; memory; rats; retinal diseases; vasodilator agents
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Cistanche deserticola (СD) has been traditionally used in the Chinese medicine as a tonic, vasodilator and neuroprotective agent. AIM OF THE STUDY: To investigate the effect of CD on the age-related behavior decline and cataract and retinopathy development in senescent accelerated OXYS rats. MATERIALS AND METHODS: OXYS and Wistar (control) rats were supplemented wit ...
DOI:
10.1016/j.jep.2011.10.017
PubMed:
22020276

43. Effects of Rubus coreanus extract on visual processes in bullfrog's eye

Author:
Wahid, Fazli; Jung, Hyuk; Khan, Taous; Hwang, Kyung-hee; Park, Jong Seok; Chang, Su-Chan; Khan, Mir Azam; Kim, You Young
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 333-339
ISSN:
0378-8741
Subject:
Rubus coreanus; antagonists; ejaculation; electroretinography; fruits; gamma-aminobutyric acid; kidneys; lipid peroxidation; liver diseases; receptors; retina; vertebrates; vision
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: The fruit of Rubus coreanus (Rosaceae) is traditionally used as an aphrodisiac, astringent, restorative and tonic in Asian countries. It is advised for treating diseases related to liver, kidney and urinary dysfunction, premature greying, blurred vision, infertility, impotence and premature ejaculation. Additionally, there is a long history of different parts of the ...
DOI:
10.1016/j.jep.2011.07.027
PubMed:
21787855

44. Fructus panax ginseng extract promotes hair regeneration in C57BL/6 mice

Author:
Park, Soojin; Shin, Weon-Sun; Ho, Jinnyoung
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 340-344
ISSN:
0378-8741
Subject:
Panax ginseng; alopecia; apoptosis; bromides; cell proliferation; ethanol; hairs; humans; mice; tetrazolium
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Radix panax ginseng (Panax ginseng C.A. Meyer, Araliaceae, RPG) has been documented to possess hair growth activity and widely used to treat alopecia, while no report has been issued to date on the effect of Fructus panax ginseng (FPG) on hair regeneration. MATERIALS AND METHODS: To investigate the effects of FPG extract on the proliferation of human hair dermal pap ...
DOI:
10.1016/j.jep.2011.08.013
PubMed:
21959181

45. Furfuran lignans and a flavone from Artemisia gorgonum Webb and their in vitro activity against Plasmodium falciparum

Author:
Ortet, Risoleta; Prado, Soizic; Regalado, Erik L.; Valeriote, Frederick A.; Media, Joseph; Mendiola, Judith; Thomas, Olivier P.
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 637-640
ISSN:
0378-8741
Subject:
Artemisia; Plasmodium falciparum; aerial parts; chemical composition; colon; cytotoxicity; humans; indigenous species; lignans; mice; neoplasms
Abstract:
... The chemical composition of the aerial parts of the Cape Verdean endemic shrub Artemisia gorgonum Webb (Asteraceae) was careful investigated, which led to the isolation and identification of six known furfuran lignans: eudesmin (1), magnolin (2), epimagnolin A (3), aschantin (4), kobusin (5), sesamin (6) and a flavone: artemetin (7). Compounds 1–7 were evaluated in vitro for their cytotoxicity in ...
DOI:
10.1016/j.jep.2011.09.039
PubMed:
21982788

46. Gastroprotective activity of hydroalcoholic extract obtained from the leaves of Brassica oleracea var. acephala DC in different animal models

Author:
Lemos, Marivane; Santin, José Roberto; Júnior, Luiz Carlos Klein; Niero, Rivaldo; Andrade, Sérgio Faloni de
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 503-507
ISSN:
0378-8741
Subject:
Brassica oleracea; acute toxicity; animal models; anti-ulcer activity; cimetidine; ions; leaves; mucus; nonsteroidal anti-inflammatory agents; pH; pylorus; secretion; stomach ulcers; toxicity testing; traditional medicine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Brassica oleracea var. acephala DC has been extensively used in Brazilian traditional medicine to treat gastric ulcer. AIM OF THE STUDY: This study was conducted to evaluate the antiulcerogenic property of hydroalcoholic extract obtained from the leaves of Brassica oleracea. MATERIALS AND METHODS: Antiulcer assays were performed using the protocol of ulcer induced b ...
DOI:
10.1016/j.jep.2011.09.046
PubMed:
21986229

47. Ginsenoside Rg1 inhibits vascular intimal hyperplasia in balloon-injured rat carotid artery by down-regulation of extracellular signal-regulated kinase 2

Author:
Gao, Yang; Deng, Jiang; Yu, Xue-Fang; Yang, Dan-Li; Gong, Qi-Hai; Huang, Xie-Nan
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 472-478
ISSN:
0378-8741
Subject:
Panax ginseng; animal models; carotid arteries; catheters; drug therapy; gene expression; herbal medicines; histopathology; hyperplasia; immunohistochemistry; messenger RNA; mitogen-activated protein kinase; myocytes; necrosis; neoplasms; phosphoprotein phosphatase; proliferating cell nuclear antigen; protein synthesis; proto-oncogenes; rats; smooth muscle
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Ginsenoside Rg1 (Rg1) is one of the main active components of Panax ginseng a well-known herbal medicine. It has been demonstrated to inhibit proliferation of vascular smooth muscle cells (VSMCs) induced by tumor necrosis factor-αin vitro. The present study is aimed to examine the possible effects of Rg1 on vascular neointimal hyperplasia in balloon-injured carotid ...
DOI:
10.1016/j.jep.2011.09.029
PubMed:
21964194

48. Helichrysum plicatum DC. subsp. plicatum extract as a preventive agent in experimentally induced urolithiasis model

Author:
Bayir, Yasin; Halici, Zekai; Keles, Mevlut Sait; Colak, Suat; Cakir, Ahmet; Kaya, Yusuf; Akçay, Fatih
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 408-414
ISSN:
0378-8741
Subject:
Helichrysum; calcium; calcium oxalate; drugs; ethylene glycol; kidneys; magnesium; models; phosphorus; rats; renal calculi; urea nitrogen; uric acid; urine
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Since ancient times, various herbal preparations have been used in treatment of urolithiasis, which is basically formation of calcium oxalate stones in kidney. The aim of our study is to assess the effects of Helichrysum plicatum DC. subsp. plicatum (HP) as a preventive agent in experimentally induced urolithiasis model in rats. MATERIALS AND METHODS: The efficacy o ...
DOI:
10.1016/j.jep.2011.09.026
PubMed:
21963562

49. Inhibitory effects of Chelidonium majus extract on atopic dermatitis-like skin lesions in NC/Nga mice

Author:
Yang, Gabsik; Lee, Kyungjin; Lee, Mi-Hwa; Kim, So-Hyung; Ham, In-Hye; Choi, Ho-Young
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 398-403
ISSN:
0378-8741
Subject:
Chelidonium majus; atopic dermatitis; ears; histology; immunoglobulin E; mice; models; skin lesions
Abstract:
... AIM OF THE STUDY: Chelidonium majus (CM) has traditionally been used for treatment of various inflammatory diseases including atopic dermatitis (AD). However its action on atopic dermatitis (AD) is unclear. Therefore, we investigated the effect of CM on AD using NC/Nga mice as an AD model. MATERIALS AND METHODS: The effect of CM on 1-chloro-2,4-dinitrobenzene (DNCB) induced NC/Nga mice was evaluat ...
DOI:
10.1016/j.jep.2011.09.028
PubMed:
21963561

50. Intracellular replication inhibitory effects of Galla Rhois ethanol extract for Brucella abortus infection

Author:
Lee, Jin Ju; Bae, Jae Hyung; Kim, Dong Hyeok; Lim, Jeong Ju; Kim, Dae Geun; Lee, Hu Jang; Min, Wongi; Rhee, Man Hee; Chang, Hong Hee; Park, Hyun; Kim, Suk
Source:
Journal of ethnopharmacology 2011 v.138 no.2 pp. 602-609
ISSN:
0378-8741
Subject:
Brucella melitensis biovar Abortus; Oriental traditional medicine; antibacterial properties; bacteria; brucellosis; ethanol; macrophages; mice; monitoring; parasitoses; phagosomes; spleen; viability
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Galla Rhois (GR) has long been applied in traditional Korean and Oriental medicine. Although GR has an anti-bacterial effect, the anti-bacterial mechanism and therapeutic efficiency of GR for intracellular parasitic Brucella infection are still unclear. AIM OF THE STUDY: The objective of this study was to investigate the antibacterial and therapeutic effects of GR e ...
DOI:
10.1016/j.jep.2011.10.007
PubMed:
22008879