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- Author:
- Ko, Byoung-Seob; Ryuk, Jin Ah; Hwang, Joo Tae; Zhang, Ting; Wu, Xuangao; Kim, Hye Jin; Yi, Qiu Jing; Park, Sunmin
- Source:
- Journal of functional foods 2019 v.58 pp. 151-160
- ISSN:
- 1756-4646
- Subject:
- Allium fistulosum; Japanese bunching onions; Portulaca oleracea; adolescence; cell proliferation; femur; growth plate; insulin-like growth factor I; legs; males; osteoblasts; rats; roots; somatotropin; tibia; transforming growth factor beta; weanlings
- Abstract:
- ... Longitudinal bone growth mainly occurs during adolescence and can be enhanced by growth hormones. We hypothesized that water extracts from roots of Allium fistulosum L. (Welsh onion, WO; 15 or 45 mg/kg bw/day) and Portulaca oleracea L. (PO; 15 or 45 mg/kg bw/day) can stimulate longitudinal bone growth in weanling male rats for 4 weeks. Femur and tibia lengths were higher in the WO-H and PO-H group ...
- DOI:
- 10.1016/j.jff.2019.04.061
-
https://dx.doi.org/10.1016/j.jff.2019.04.061
- Author:
- Liu, Yixiang; Zhang, Di; Liu, Guang-Ming; Chen, Qingchou; Lu, Zhenhua
- Source:
- Journal of functional foods 2019 v.58 pp. 44-55
- ISSN:
- 1756-4646
- Subject:
- Laminaria; Saccharina japonica; beta oxidation; blood lipids; body weight changes; carnitine; fatty acids; fatty liver; high fat diet; lipid composition; liver; mice; peroxisome proliferator-activated receptor alpha; polyphenols; protein kinases; spectral analysis; visceral fat
- Abstract:
- ... An increasing number of studies indicate that dietary polyphenols are beneficial to non-alcoholic fatty liver (NAFL) disease. However, the published reports about marine polyphenols are still limited. In this work, the ameliorative effect of polyphenols from Laminaria (L.) japonica on NAFL was investigated in vivo. According to the spectral analyses, dieckol was identified from L. japonica. After ...
- DOI:
- 10.1016/j.jff.2019.04.051
-
https://dx.doi.org/10.1016/j.jff.2019.04.051
- Author:
- Mwakalukwa, Rogers; Ashour, Ahmed; Amen, Yhiya; Niwa, Yasuharu; Tamrakar, Sonam; Miyamoto, Tomofumi; Shimizu, Kuniyoshi
- Source:
- Journal of functional foods 2019 v.58 pp. 207-217
- ISSN:
- 1756-4646
- Subject:
- acetates; anti-allergic agents; calcium; calcium channels; food processing wastes; inhibitory concentration 50; luteolin; mast cells; oleuropein; polyphenols; stabilizers
- Abstract:
- ... We report the isolation and anti-allergic activity (degranulation reduction) of six polyphenolic compounds, one of them being novel, from olive mill wastes (OMW). Additionally, we evaluated their ability to reduce; intracellular Ca2+ levels and expression of calcium channel proteins in RBL-2H3 cells, to assist the possible characterization of the mechanisms involved. The novel compound, new hemial ...
- DOI:
- 10.1016/j.jff.2019.04.058
-
https://dx.doi.org/10.1016/j.jff.2019.04.058
- Author:
- Xu, Shiwei; Shen, Yanting; Xu, Jingwen; Qi, Guangyan; Chen, Gengjun; Wang, Weiqun; Sun, Xiuzhi; Li, Yonghui
- Source:
- Journal of functional foods 2019 v.58 pp. 374-382
- ISSN:
- 1756-4646
- Subject:
- antineoplastic activity; antioxidant activity; antioxidants; cell growth; emulsions; food industry; fractionation; ground meat; hepatoma; human cell lines; hydrolysates; hydrolysis; kafirins; lipid peroxidation; oxidation; peptides; reversed-phase high performance liquid chromatography; turbidity; ultrafiltration
- Abstract:
- ... Peptide antioxidants are becoming increasingly popular in the food industry. This study reported antioxidant and anticancer properties of papain-hydrolyzed sorghum kafirin. The optimum hydrolysis conditions were determined to be 360 kU/g enzyme-to-substrate ratio, and 4 h of reaction time. After ultrafiltration, the 1–3 kDa hydrolysate fraction demonstrating promising antioxidative activities as w ...
- DOI:
- 10.1016/j.jff.2019.05.016
-
https://dx.doi.org/10.1016/j.jff.2019.05.016
- Author:
- Kim, Sunggun; Kim, Soo Jeong; Jo, Eun-Sang; Gil, Kicheol; Kim, Na-Yeon; Park, Ji Sung; Park, Dongbok; Park, So-Young; Hwang, Kwang Woo
- Source:
- Journal of functional foods 2019 v.58 pp. 301-310
- ISSN:
- 1756-4646
- Subject:
- antineoplastic activity; beta-carotene; cabbage; functional foods; immunity; in vitro studies; mechanism of action; mice; models; pancreatic neoplasms; spleen; viability
- Abstract:
- ... We aimed to investigate possible anticancer effects of Amtak-ssamchae (a newly bred cabbage line containing more carotenoids) in an in vitro pancreatic-tumor cell model and an in vivo model (Panc02 cells). In an in vitro assay, Amtak-ssamchae significantly reduced the viability of Panc02 cells relative to normal ssamchae. Furthermore, an Amtak-ssamchae extract significantly reduced the tumor size ...
- DOI:
- 10.1016/j.jff.2019.05.006
-
https://dx.doi.org/10.1016/j.jff.2019.05.006
- Author:
- Lee, Na-Kyoung; Hong, Ji-Young; Yi, Sung-Hun; Hong, Sang-Pil; Lee, Jang-Eun; Paik, Hyun-Dong
- Source:
- Journal of functional foods 2019 v.58 pp. 324-329
- ISSN:
- 1756-4646
- Subject:
- DNA; Saccharomyces cerevisiae; acid phosphatase; alpha-glucosidase; beta-glucans; bile; bioactive compounds; cell adhesion; cucumbers; epithelial cells; functional foods; glutathione; leucine; probiotics; spermidine; starter cultures; toxicity
- Abstract:
- ... The bioactive compounds and probiotic properties of three Saccharomyces cerevisiae strains isolated from cucumber jangajji were investigated. The β-glucan contents of S. cerevisiae KU200270, KU200280, and KU200284 were 4.09%, 7.45%, and 13.97%, respectively, and the glutathione contents of the strains were in the range of 3.19–6.03 mg/g dry cells. The l-ornithine and spermidine contents were 2.98– ...
- DOI:
- 10.1016/j.jff.2019.04.059
-
https://dx.doi.org/10.1016/j.jff.2019.04.059
- Author:
- Lin, Shaoling; Wang, Zhenyu; Lin, Yilin; Ge, Shenghan; Hamzah, Siti Sarah; Hu, Jiamiao
- Source:
- Journal of functional foods 2019 v.58 pp. 74-84
- ISSN:
- 1756-4646
- Subject:
- adipocytes; polyphenols; foods; high fat diet; adiponectin; lipid composition; signal transduction; lipids; genes; obesity; phosphorylation; oral administration; body weight changes; peroxisome proliferator-activated receptor gamma; gene expression regulation; blood lipids; seeds; ellagic acid; mice; AMP-activated protein kinase
- Abstract:
- ... Polyphenols are found in free and bound forms in foods, both of which exert a wide range of pharmacological and therapeutic effects. Here, 3T3-L1 pre-adipocytes and high-fat diet (HFD)-induced mice were used to investigate the potential anti-obesity effect of bound phenolics extracted from lotus seeds (LBP). Phenolic compounds including protocatechuic, caffeic and ellagic acids were identified in ...
- DOI:
- 10.1016/j.jff.2019.04.054
-
https://dx.doi.org/10.1016/j.jff.2019.04.054
- Author:
- Gut, Abraham Majak; Vasiljevic, Todor; Yeager, Thomas; Donkor, Osaana N.
- Source:
- Journal of functional foods 2019 v.58 pp. 56-66
- ISSN:
- 1756-4646
- Subject:
- Kluyveromyces marxianus var. lactis; Saccharomyces cerevisiae var. cerevisiae; bacteria; enzyme activity; exopolysaccharides; gastrointestinal system; hydrophobicity; internal transcribed spacers; intestinal microorganisms; kefir; phospholipases; probiotics; proteolysis; ribosomal DNA; survival rate; yeasts
- Abstract:
- ... Kefir is a mixed fermented product with numerous attributed health benefits due to presence of a complex culture composed of bacteria and yeasts in an exopolysaccharide matrix. This work aimed at isolating and identifying yeast species from two types of traditional kefir grains and establishing some potential probiotic properties including survival in the gastrointestinal tract, auto-aggregation, ...
- DOI:
- 10.1016/j.jff.2019.04.046
-
https://dx.doi.org/10.1016/j.jff.2019.04.046
- Author:
- Li, Yanfang; Hao, Yiming; Gao, Boyan; Geng, Ping; Huang, Haiqiu; Yu, Lu; Choe, Uyory; Liu, Jie; Sun, Jianghao; Chen, Pei; Wang, Thomas T.Y.; Yu, Liangli (Lucy)
- Source:
- Journal of functional foods 2019 v.58 pp. 114-122
- ISSN:
- 1756-4646
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Bacteroidetes; Bifidobacterium; Chrysanthemum morifolium; Firmicutes; agricultural economics; antioxidant activity; drinking; ethanol; free radical scavengers; functional foods; gallic acid; glucosides; ingredients; intestinal microorganisms; reactive oxygen species; tea
- Abstract:
- ... Hot-water and ethanol extracts of Chrysanthemum morifolium cv. Fubaiju were investigated for their chemical compositions, effects on gut microbiota, anti-inflammatory, and free radical scavenging capacities. UPLC-IMS-QTOF-MS analysis detected tuberonic acid glucoside and tasumatrol B in the Fubaiju for the first time. The hot-water extract had greater anti-inflammation and free radical scavenging ...
- DOI:
- 10.1016/j.jff.2019.04.053
-
https://dx.doi.org/10.1016/j.jff.2019.04.053
- Author:
- Baião, Diego dos Santos; d'El-Rei, Jenifer; Alves, Genilton; Fritsch Neves, Mario; Perrone, Daniel; Del Aguila, Eduardo Mere; Flosi Paschoalin, Vania M.
- Source:
- Journal of functional foods 2019 v.58 pp. 85-94
- ISSN:
- 1756-4646
- Subject:
- antioxidant activity; beets; biotransformation; blood pressure; cardiovascular diseases; in vitro digestion; intestines; long term effects; nitrates; nitric oxide; nitrites; patients; placebos; polyphenols; risk factors
- Abstract:
- ... Dietary nitrate has been associated with nitric oxide bioconversion and beneficial vascular effects. A randomized, controlled, crossover and placebo 3-week supplementation trial with a beetroot-cereal bar enriched in nitrate (9.5 ± 0.05 mmol) and polyphenols was performed on patients displaying three risk factors for the development of cardiovascular diseases. The beetroot-cereal bar formulation w ...
- DOI:
- 10.1016/j.jff.2019.04.041
-
https://dx.doi.org/10.1016/j.jff.2019.04.041
- Author:
- Gandhi, Kamal; Devi, Savita; Gautam, Priyae Brath; Sharma, Rajan; Mann, Bimlesh; Ranvir, Suvartan; Sao, Khushbu; Pandey, Vanita
- Source:
- Journal of functional foods 2019 v.58 pp. 275-281
- ISSN:
- 1756-4646
- Subject:
- anemia; antioxidants; bioavailability; blood serum; catalase; digestibility; dried whey; enzyme activity; ferritin; hemoglobin; high density lipoprotein cholesterol; iron; lipid composition; lipid peroxidation; liver; low density lipoprotein; nitric oxide; nutrient deficiencies; rats; spray drying; transferrin; triacylglycerols; very low density lipoprotein; weaning; whey protein
- Abstract:
- ... The lower bioavailability of iron from the diet has led to iron deficiency and several ill-effects on health. The objective of this study was to assess the bioavailability of iron from spray dried whey protein concentrate-iron (WPC-Fe) complex in weaning and anaemic rats. Blood hemoglobin level, bioavailability, lipid profile, antioxidant status and concentration of iron delivery molecules were an ...
- DOI:
- 10.1016/j.jff.2019.05.008
-
https://dx.doi.org/10.1016/j.jff.2019.05.008
- Author:
- Graham, Ken; Rea, Rosemary; Simpson, Paul; Stack, Helena
- Source:
- Journal of functional foods 2019 v.58 pp. 292-300
- ISSN:
- 1756-4646
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Enterococcus faecalis; alpha-glucosidase; antioxidant activity; antioxidants; enzyme inhibition; fermented milk; hyperglycemia; hypertension; milk; peptidyl-dipeptidase A; therapeutics
- Abstract:
- ... In this study, Enterococcus faecalis milk fermentates were assayed for total phenolic content, related antioxidant activity and the inhibition of key enzymes linked to hypertension and hyperglycaemia. Of the 25 isolates, milk fermented with E. faecalis DPC5154 had the highest level of total phenolic compounds (739.06 µg GAE/ml) and demonstrated the highest level of Trolox Equivalent Antioxidant Ac ...
- DOI:
- 10.1016/j.jff.2019.04.052
-
https://dx.doi.org/10.1016/j.jff.2019.04.052
- Author:
- de los Santos, Sergio; Coral-Vázquez, Ramón Mauricio; Menjivar, Marta; Granados-Silvestre, María de los Ángeles; Tejeda, María Elena; Reyes-Castro, Luis Antonio; Méndez, Juan Pablo; Zambrano, Elena; Canto, Patricia
- Source:
- Journal of functional foods 2019 v.58 pp. 367-373
- ISSN:
- 1756-4646
- Subject:
- animal disease models; bone density; high fat diet; males; muscles; obesity; progeny; rats; visceral fat
- Abstract:
- ... The aim of our study was to determine if two protocols of (−)-epicatechin (Epi) (short and long) can modify fat, muscle and bone mass, in the male offspring of the maternal rat obesity model induced by high-fat diet (HFD). Four male offspring per group from different litters were randomly selected to the control or Epi intervention groups. We administered Epi twice daily/13 weeks (long) or for two ...
- DOI:
- 10.1016/j.jff.2019.05.014
-
https://dx.doi.org/10.1016/j.jff.2019.05.014
- Author:
- de Sousa, Andressa Rodrigues; de Castro Moreira, Maria Eliza; Grancieri, Mariana; Toledo, Renata Celi Lopes; de Oliveira Araújo, Fernanda; Mantovani, Hilário Cuquetto; Queiroz, Valéria Aparecida Vieira; Martino, Hercia Stampini Duarte
- Source:
- Journal of functional foods 2019 v.58 pp. 282-291
- ISSN:
- 1756-4646
- Subject:
- Bacteroidetes; Firmicutes; Sorghum bicolor; animal disease models; antioxidant activity; cellulose; corn starch; dysbiosis; heat shock proteins; high fat diet; inflammation; intestinal microorganisms; intestines; laboratory animals; lipid peroxidation; liver; males; obesity; oxidative stress; rats; resistin; sorghum flour; superoxide dismutase; transcription factor NF-kappa B
- Abstract:
- ... The aim of this study was to investigate the effects of extruded sorghum flour (ESF) on rats fed with a high-fat diet (HFD) on gut microbiota modulation, inflammation, and oxidative stress. Male Wistar rats were fed a normal diet (AIN-93 M, n = 8), HFD (n = 8), or HFD plus ESF replacing 50% cellulose and 100% corn starch (HFDS50, n = 8) or HFD plus ESF replacing 100% cellulose and 100% corn starch ...
- DOI:
- 10.1016/j.jff.2019.05.009
-
https://dx.doi.org/10.1016/j.jff.2019.05.009
- Author:
- Alongi, Marilisa; Calligaris, Sonia; Anese, Monica
- Source:
- Journal of functional foods 2019 v.58 pp. 130-137
- ISSN:
- 1756-4646
- Subject:
- alpha-glucosidase; bioavailability; chlorogenic acid; coffee (beverage); enzyme inhibition; homogenization; in vitro digestion; lipid content; milk; zeta potential
- Abstract:
- ... This study aimed at investigating the effect of coffee formulation and high-pressure homogenization (HPH) on chlorogenic acid bioaccessibility and α-glucosidase inhibition.Coffee was added with milk (1:1) containing 0.1, 3.6 or 7.1% fat, homogenized at increasing pressure (0–150 MPa) and in vitro digested. Using milk with the highest fat concentration (7.1%) promoted the formation of smaller parti ...
- DOI:
- 10.1016/j.jff.2019.04.057
-
https://dx.doi.org/10.1016/j.jff.2019.04.057
- Author:
- Song, Ru; Jia, Ze; Shi, Qingqing; Wei, Rongbian; Dong, Shiyuan
- Source:
- Journal of functional foods 2019 v.58 pp. 161-170
- ISSN:
- 1756-4646
- Subject:
- Maillard reaction products; Setipinna taty; anchovies; antibacterial properties; glycosylation; hydrolysates; hydrophilicity; hydrophobicity; melanoidins; synthetic peptides
- Abstract:
- ... This study investigated the effect of Maillard reaction (MR) on the antibacterial activity of half-fin anchovy hydrolysates (HAHp)-derived peptides. Eighty-two peptides (450–1400 Da) were identified from the peptidic-fraction F3 and were classified into five groups according to the presence of W, F, Y, K, H, and R residues in sequences. Increases of antibacterial activity and glycosylation content ...
- DOI:
- 10.1016/j.jff.2019.05.001
-
https://dx.doi.org/10.1016/j.jff.2019.05.001
- Author:
- Qiu, Zhixia; Liu, Qiuyan; Yu, Jiaojiao; Dai, Yu; Li, Xiaonan; Huang, Fang; Li, Ning
- Source:
- Journal of functional foods 2019 v.58 pp. 311-323
- ISSN:
- 1756-4646
- Subject:
- excretion; glucose; glucuronosyltransferases; health promotion; homeostasis; insulin resistance; pharmacokinetics; polyphenols; rats; resveratrol; sulfotransferases; tissues; transporters; urine
- Abstract:
- ... Trans-resveratrol (RES), a well-known polyphenol exerts various health-promoting benefits, including glucose homeostasis maintenance. Here, we have investigated the impact of insulin resistance (IR) on RES disposition. Rats were fed with 10%-fructose-water for 8 weeks for developing IR. The systemic exposure to RES significantly decreased (IR vs normal, AUC0-24h, 1.73, 3.79, 9.27 vs 2.50, 6.12, 12 ...
- DOI:
- 10.1016/j.jff.2019.05.007
-
https://dx.doi.org/10.1016/j.jff.2019.05.007
- Author:
- Lee, Wonkyung; Lee, Doik; Han, Euna; Choi, Junjeong
- Source:
- Journal of functional foods 2019 v.58 pp. 330-337
- ISSN:
- 1756-4646
- Subject:
- body fat; body mass index; databases; females; green tea; males; meta-analysis; obesity; placebos; systematic review; waist circumference; waist-to-hip ratio
- Abstract:
- ... Previous studies, involving males and females, evaluated the effectiveness of green tea (GT) products in obesity. However, the evidence for its health benefits was lacking when considering females, only. The objective is to examine its effectiveness in the following indicators of obesity: body mass index (BMI), body weight, waist circumference, waist-to-hip ratio, and % body fat upon the intervent ...
- DOI:
- 10.1016/j.jff.2019.05.010
-
https://dx.doi.org/10.1016/j.jff.2019.05.010
- Author:
- Li, Ze-hua; Cai, Ming; Yang, Kai; Sun, Pei-long
- Source:
- Journal of functional foods 2019 v.58 pp. 67-73
- ISSN:
- 1756-4646
- Subject:
- Citrus medica; bioactive properties; dietary supplements; droplet size; essential oils; food industry; hydrophobicity; intestines; limonene; models; mouth; nanoemulsions; oils; water solubility
- Abstract:
- ... Nanoemulsion loading finger citron essential oil (FCEO) can maintain bioactivities of FCEO and increase its water solubility. In this study, stability of FCEO nanoemulsions during digestion in vitro were evaluated and the release kinetics of d-limonene (the main component in the oil) were developed. Compared with free oil released to maximum for 6 min, all nanoemulsions kept sustainably releasing ...
- DOI:
- 10.1016/j.jff.2019.04.056
-
https://dx.doi.org/10.1016/j.jff.2019.04.056
- Author:
- Kim, Yerin; Kim, Eunju; Kim, Yuri
- Source:
- Journal of functional foods 2019 v.58 pp. 227-237
- ISSN:
- 1756-4646
- Subject:
- cadherins; carnosine; collagen; corticosterone; elderly; galactose; histidine; keratinocytes; mice; models; mortality; phosphorylation; tissue repair
- Abstract:
- ... Impaired skin wound healing in the elderly can lead to medical issues and increased mortality. Although l-histidine and l-carnosine are potent anti-aging amino acids, the wound healing effects of these amino acids in aging remain to be elucidated. Here, we investigated the regenerative potential of l-histidine and l-carnosine in in vitro and in vivo aging models. l-histidine (1 mM), l-carnosine (1 ...
- DOI:
- 10.1016/j.jff.2019.04.060
-
https://dx.doi.org/10.1016/j.jff.2019.04.060