PubAg

Main content area

You searched for: Journal Journal of functional foods Remove constraint Journal: Journal of functional foods Publication Year 2018 Remove constraint Publication Year: 2018 Source 2018 v.48 Remove constraint Source: 2018 v.48 Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
Start Over

Search

73  Search Results

« Previous | 1 - 50 of 73 |
Number of results to display per page

Search Results

1. Analysis of health-related biomarkers between vegetarians and non-vegetarians: A multi-biomarker approach

Author:
Gajski, Goran; Gerić, Marko; Vučić Lovrenčić, Marijana; Božičević, Sandra; Rubelj, Ivica; Nanić, Lucia; Škrobot Vidaček, Nikolina; Bendix, Laila; Peraica, Maja; Rašić, Dubravka; Domijan, Ana-Marija; Gluščić, Valentina; Jurasović, Jasna; Orct, Tatjana; Cvijetić Avdagić, Selma; Jurak, Gordana; Bošnir, Jasna; Garaj-Vrhovac, Vera
Source:
Journal of functional foods 2018 v.48 pp. 643-653
ISSN:
1756-4646
Subject:
DNA damage; adults; animal-based foods; antioxidant activity; arsenic; biomarkers; calcium; copper; genome; glutathione; homocysteine; mercury; nutrients; nutritional status; telomeres; toxicity; vegetarian diet; zinc
Abstract:
... This study was performed in a group of adult vegetarians (N = 40) and matched non-vegetarian subjects (N = 40) in order to analyse differences in health-related biomarkers. Obtained results revealed differences in various biomarkers between subjects on a traditional mixed and vegetarian diet, indicating that vegetarians have a lower nutritional status of some nutrients (Ca, Cu and Zn, and vitamins ...
DOI:
10.1016/j.jff.2018.07.054

2. Anthocyanins from Hibiscus sabdariffa calyx attenuate in vitro and in vivo melanoma cancer metastasis

Author:
Su, Ching-Chuan; Wang, Chau-Jong; Huang, Kai-Hsun; Lee, Yi-Ju; Chan, Wei-Ming; Chang, Yun-Ching
Source:
Journal of functional foods 2018 v.48 pp. 614-631
ISSN:
1756-4646
Subject:
anthocyanins; lungs; cell movement; melanoma; body weight; hemoglobin; metastasis; blood vessels; Hibiscus sabdariffa; patients; vascular endothelial growth factors; oral administration; mitogen-activated protein kinase; calyx
Abstract:
... Melanoma cell metastasis is the main cause of patient death. To develop more effective strategies for the prevention or treatment of melanoma, we investigated the inhibitory effects of HAs (the anthocyanin-rich extract from Hibiscus sabdariffa calyx) and explored underlying molecular mechanisms. In this study, we found that HAs significantly inhibited B16-F1 cell migration and suppressed HUVECs tu ...
DOI:
10.1016/j.jff.2018.07.032

3. Antibacterial activity and mechanism of Chuzhou chrysanthemum essential oil

Author:
Cui, Haiying; Bai, Mei; Sun, Yanhui; Abdel-Samie, Mohamed Abdel-Shafi; Lin, Lin
Source:
Journal of functional foods 2018 v.48 pp. 159-166
ISSN:
1756-4646
Subject:
Chrysanthemum; DNA topoisomerase; DNA topoisomerase (ATP-hydrolysing); Escherichia coli; antibacterial properties; bacteria; cell membranes; enzyme activity; enzyme inhibition; essential oils; glycolysis; oils; polyacrylamide gel electrophoresis; protein content; proteins; tea; China
Abstract:
... Chuzhou chrysanthemum is well-known in China and has been used to make tea over centuries. However, neither integrated background about the antibacterial activity nor the antibacterial mechanism of Chuzhou chrysanthemum oil (CCO) is available. SDS-PAGE analysis, oxidative respiratory metabolism measurement and the DNA topoisomerase activity were employed to investigate the antibacterial mechanism ...
DOI:
10.1016/j.jff.2018.07.021

4. Antioxidant peptides derived from the hydrolyzate of purple sea urchin (Strongylocentrotus nudus) gonad alleviate oxidative stress in Caenorhabditis elegans

Author:
Zhao, Sixu; Cheng, Qiong; Peng, Qiong; Yu, Xuesong; Yin, Xiquan; Liang, Ming; Ma, Chung Wah; Huang, Zebo; Jia, Weizhang
Source:
Journal of functional foods 2018 v.48 pp. 594-604
ISSN:
1756-4646
Subject:
Caenorhabditis elegans; RNA interference; Strongylocentrotus nudus; Strongylocentrotus purpuratus; antioxidant activity; gel chromatography; genes; heat stress; high performance liquid chromatography; hydrolysates; oxidative stress; papain; peptides; reactive oxygen species; signal transduction; superoxide dismutase; tandem mass spectrometry; ultrafiltration
Abstract:
... The papain hydrolyzate prepared from purple sea urchin (Strongylocentrotus nudus) gonad exerts significant antioxidant activity. Through ultrafiltration, gel filtration and high performance liquid chromatography, the active fractions from the hydrolyzate were screened by alleviating paraquat-induced oxidative stress in Caenorhabditis elegans, and the peptide components were identified by liquid ch ...
DOI:
10.1016/j.jff.2018.07.060

5. Apigenin: A natural bioactive flavone-type molecule with promising therapeutic function

Author:
Kashyap, Dharambir; Sharma, Ajay; Tuli, Hardeep Singh; Sak, Katrin; Garg, Vivek Kumar; Buttar, Harpal Singh; Setzer, William N.; Sethi, Gautam
Source:
Journal of functional foods 2018 v.48 pp. 457-471
ISSN:
1756-4646
Subject:
antineoplastic activity; antineoplastic agents; antioxidants; apigenin; biochemical mechanisms; cardiovascular diseases; cell lines; cell proliferation; citrus fruits; herbs; neoplasm cells; neoplasms; neurodegenerative diseases; signal transduction; spices; therapeutics; tissues; vegetables
Abstract:
... There exist overwhelming evidence that plant-derived bioactive flavonoids possess strong therapeutic activities against cancer, cardiovascular diseases, and age-related neurodegenerative disorders. Several drug discovery studies have suggested the therapeutic potential of apigenin (APG) are due to its strong anti-inflammatory, anti-oxidant, and anti-tumor properties. APG is found in citrus fruits, ...
DOI:
10.1016/j.jff.2018.07.037

6. A pivotal peptide (Val-Ser-Glu-Glu) from duck egg white promotes calcium uptake and structure-activity relationship study

Author:
Hou, Tao; Lu, Yulin; Guo, Danjun; Liu, Weiwei; Shi, Wen; He, Hui
Source:
Journal of functional foods 2018 v.48 pp. 448-456
ISSN:
1756-4646
Subject:
active sites; alkaline phosphatase; amino acids; animal models; blood serum; calcium; calcium carbonate; diet; duck eggs; egg albumen; intestinal absorption; molecular models; oral administration; osteocalcin; peptides; rats; structure-activity relationships; tibia
Abstract:
... The effects of desalted duck egg white peptides (DPs) and Val-Ser-Glu-Glu (VSEE) on calcium absorption were investigated in calcium-deficient diets rat model. Six-week oral administration results indicated DPs + CaCO3 and VSEE + CaCO3 were significantly higher than CaCO3 group in calcium absorption, serum osteocalcin, bone calcium content and max load, but lower in serum bone alkaline phosphatase ...
DOI:
10.1016/j.jff.2018.07.034

7. A polyphenol-rich prebiotic in combination with a novel probiotic formulation alleviates markers of obesity and diabetes in Drosophila

Author:
Westfall, Susan; Lomis, Nikita; Prakash, Satya
Source:
Journal of functional foods 2018 v.48 pp. 374-386
ISSN:
1756-4646
Subject:
Bifidobacterium; Drosophila melanogaster; Lactobacillus fermentum; Lactobacillus plantarum; diabetes; glucose; high carbohydrate diet; insulin resistance; intestinal microorganisms; lipogenesis; obesity; pathogenesis; prebiotics; probiotics; therapeutics; triacylglycerols
Abstract:
... Imbalances in the gut microbiota are directly associated with the pathogenesis of diabetes and obesity. The current study investigates how the combination of three probiotics Lactobacillus plantarum NCIMB 8826, L. fermentum NCIMB 5221 and Bifidobacteria longum subsp. infantis NCIMB 702255 with a novel polyphenol-rich prebiotic Triphala has combinatorial benefits on the symptoms and underlying mech ...
DOI:
10.1016/j.jff.2018.07.012

8. A soy-based probiotic drink modulates the microbiota and reduces body weight gain in diet-induced obese mice

Author:
de Carvalho Marchesin, Juliana; Celiberto, Larissa Sbaglia; Orlando, Allan Botinhon; de Medeiros, Alexandra Ivo; Pinto, Roseli Aparecida; Zuanon, José Antônio Sampaio; Spolidorio, Luis Carlos; dos Santos, Andrey; Taranto, Maria Pía; Cavallini, Daniela Cardoso Umbelino
Source:
Journal of functional foods 2018 v.48 pp. 302-313
ISSN:
1756-4646
Subject:
Bacteroidetes; Bifidobacterium longum; Enterococcus faecium; Lactobacillus; adipocytes; animal disease models; body weight changes; high fat diet; interleukin-10; interleukin-6; intestinal microorganisms; mice; obesity; probiotics
Abstract:
... This work investigates the effect of a soy-based probiotic drink (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) on the fecal microbiota composition, body weight and inflammatory parameters in diet-induced obese mice. The probiotic group had a lower body weight until 9th week of the study, reduced area and diameter of adipocytes, and showed a significant increase of IL-6 and I ...
DOI:
10.1016/j.jff.2018.07.010

9. Beneficial changes of gut microbiota and metabolism in weaned rats with Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 supplementation

Author:
Wang, Mengxia; Chen, Yongxiong; Wang, Yuanyuan; Li, Yuan; Zhang, Xiaojun; Zheng, Haihui; Ma, Fangli; Ma, ChungWah; Lu, Biyu; Xie, Zhiyong; Liao, Qiongfeng
Source:
Journal of functional foods 2018 v.48 pp. 252-265
ISSN:
1756-4646
Subject:
Acinetobacter; Bifidobacterium animalis subsp. lactis; Enterococcus; Jeotgalicoccus; Lactobacillus acidophilus; Oligella; bacterial communities; choline; creatine; digestive system; intestinal microorganisms; ketone bodies; laboratory animals; lactic acid; males; metabolism; probiotics; rats; short chain fatty acids
Abstract:
... To investigate the effect of Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 (1:1) on microbiota composition and function, metabolism as well as microbiota-metabolite relationships of weaned rats, four groups of male Sprague-Dawley rats were orally supplemented with either probiotics (2.5 × 1010 cfu/kg, 5.0 × 1010 cfu/kg, 1.0 × 1011 cfu/kg) or vehicle (water) for 28 days. Lactobaci ...
DOI:
10.1016/j.jff.2018.07.008

10. Beneficial effects of Aloe vera gel on lipid profile, lipase activities and oxidant/antioxidant status in obese rats

Author:
Rahoui, Walid; Merzouk, Hafida; El Haci, Imad Abdelhamid; Bettioui, Reda; Azzi, Rachid; Benali, Mohamed
Source:
Journal of functional foods 2018 v.48 pp. 525-532
ISSN:
1756-4646
Subject:
Aloe vera; adipose tissue; animal models; antioxidant activity; antioxidants; carboxylic ester hydrolases; enzyme activity; functional foods; gels; hyperlipidemia; lipid composition; lipids; lipolysis; obesity; oxidants; oxidative stress; protective effect; rats
Abstract:
... Natural products can be very effective in the prevention of obesity-related metabolic disorders. The aim of the present study was to investigate the anti-obesity effects of Aloe vera (Aloe barbadensis Miller) gel administration at 100 and 200 mg/kg/day, in a diet-induced obesity rat model. The whole gel was used. Plasma and tissue parameters and adipose lipase activities were determined. Our resul ...
DOI:
10.1016/j.jff.2018.07.050

11. Combination of pH-controlled fermentation in mild acidic conditions and enzymatic hydrolysis by Savinase to improve metabolic health-promoting properties of lentil

Author:
Bautista-Expósito, Sara; Martínez-Villaluenga, Cristina; Dueñas, Montserrat; Silván, Jose Manuel; Frias, Juana; Peñas, Elena
Source:
Journal of functional foods 2018 v.48 pp. 9-18
ISSN:
1756-4646
Subject:
4-hydroxybenzoic acid; Lactobacillus plantarum; alpha-glucosidase; antioxidant activity; antioxidants; digestion; enzymatic hydrolysis; enzyme activity; enzyme inhibition; fermentation; flavonols; gastrointestinal system; health promotion; ingredients; lentils; metabolic syndrome; peptides; peptidyl-dipeptidase A; sucrose alpha-glucosidase
Abstract:
... This work evaluated the feasibility of pH-controlled fermentation by Lactobacillus plantarum CECT 748 combined with Savinase-hydrolysis (LPHS) for producing multifunctional lentil ingredients targeted for metabolic syndrome (MetS) relieving. LPHS process was compared with L. plantarum-fermentation (LP) and Savinase-hydrolysis (HS), applied separately. LPHS soluble fraction exhibited higher peptide ...
DOI:
10.1016/j.jff.2018.06.019

12. Comparative bio-accessibility, bioavailability and bioequivalence of quercetin, apigenin, glucoraphanin and carotenoids from freeze-dried vegetables incorporated into a baked snack versus minimally processed vegetables: Evidence from in vitro models and a human bioavailability study

Author:
Perez-Moral, Natalia; Saha, Shikha; Philo, Mark; Hart, Dave J.; Winterbone, Mark S.; Hollands, Wendy J.; Spurr, Mike; Bows, John; van der Velpen, Vera; Kroon, Paul A.; Curtis, Peter J.
Source:
Journal of functional foods 2018 v.48 pp. 410-419
ISSN:
1756-4646
Subject:
apigenin; bioavailability; carotenes; freeze drying; glucoraphanin; models; pharmacokinetics; phytopharmaceuticals; quercetin; snacks; vegetables
Abstract:
... The aim was to incorporate vegetables containing the phytochemicals quercetin, apigenin, glucoraphanin and carotenoids into a processed potato-based snack and assess their bioaccessibility and bioavailability. Three different processing routes were tested for incorporation and retention of phytochemicals in snacks using individually quick frozen or freeze-dried vegetables. No significant differenc ...
DOI:
10.1016/j.jff.2018.07.035

13. Components of heat-treated Helianthus annuus L. pectin inhibit tumor growth and promote immunity in a mouse CT26 tumor model

Author:
Guan, Yuan; Zhang, Zhongyu; Yu, Xiyao; Yan, Jingmin; Zhou, Yifa; Cheng, Hairong; Tai, Guihua
Source:
Journal of functional foods 2018 v.48 pp. 190-199
ISSN:
1756-4646
Subject:
Helianthus annuus; antineoplastic activity; apoptosis; colorectal neoplasms; fluorouracil; galacturonic acid; heat treatment; immunity; mechanism of action; mice; models; pectins; spleen; thymus gland; toxicity
Abstract:
... Heat-treated pectin is known to have anti-tumor activity. The present study was designed to identify its active components and mechanism of action. Here, we investigated the anti-tumor effect of heat-treated Helianthus annuus L. pectin (HT-HAP), alkali-inactivated HT-HAP representing the pectin fragment fraction (HT-HAP-P), and heat-treated galacturonic acid representing the small molecule fractio ...
DOI:
10.1016/j.jff.2018.07.001

14. Consumption of virgin coconut oil in Wistar rats increases saturated fatty acids in the liver and adipose tissue, as well as adipose tissue inflammation

Author:
de Moura e Dias, Mariana; Pais Siqueira, Nathane; Lopes da Conceição, Lisiane; Aparecida dos Reis, Sandra; Xavier Valente, Flávia; Maciel dos Santos Dias, Manoela; de Oliveira Barbosa Rosa, Carla; Oliveira de Paula, Sérgio; da Matta, Sérgio Luís Pinto; Licursi de Oliveira, Leandro; Bressan, Josefina; Gouveia Peluzio, Maria do Carmo
Source:
Journal of functional foods 2018 v.48 pp. 472-480
ISSN:
1756-4646
Subject:
adipocytes; adipose tissue; antimicrobial properties; antioxidants; blood lipids; body measurements; coconut oil; dose response; food intake; genes; inflammation; laboratory animals; lipid composition; liver; morphometry; rats; saturated fatty acids; soybean oil
Abstract:
... The recommended amount of intake of virgin coconut oil (VCO) for health benefits has not been defined. This study aims to evaluate the effects of partial dietary substitution of lipid source by VCO in the health of Wistar rats. The animals were divided as: G1, 100% of soybean oil; G2, 10.4% of VCO; G3, 50% of VCO; and G4, 95% of VCO. Weight and body measurements were not affected by substitution, ...
DOI:
10.1016/j.jff.2018.07.036

15. Defatted walnut powder extract reduces cholesterol gallstones formation in C57BL/6 mice by downregulating the levels of ABCG5/8 in the liver and NPC1L1 in the intestine

Author:
Ren, Shumeng; Yan, Xiaowei; Ma, Jing; Pan, Yingni; Zhang, Wei; Wang, Dongmei; Fei, Zhongping; Liu, Xiaoqiu
Source:
Journal of functional foods 2018 v.48 pp. 85-91
ISSN:
1756-4646
Subject:
absorption; bile; cholelithiasis; cholesterol; diet; ellagic acid; ethyl gallate; intestines; liver; methyl gallate; mice; protective effect; proteins; seeds; walnut oil; walnuts; China
Abstract:
... Walnut kernel is often used to treat cholesterol gallstones (CGS) in China. Few studies have reported the effect of DWPE (defatted walnut powder extract) or walnut oil (WO) on anti-CGS and effect mechanism. In this studies, there were glansreginin A, ellagic acid, gallic acid, methyl gallate, and ethyl gallate in DWPE. Then, inhibitory effects of DWPE and WO on CGS were compared in C57BL/6 mice wi ...
DOI:
10.1016/j.jff.2018.06.017

16. Different oils used as supplement during lactation causes endocrine-metabolic dysfunctions in male rats

Author:
Quitete, Fernanda Torres; Lisboa, Patricia C.; de Moura, Egberto Gaspar; de Oliveira, Elaine
Source:
Journal of functional foods 2018 v.48 pp. 43-53
ISSN:
1756-4646
Subject:
cholesterol; coconut oil; fish; fish oils; lactation; males; metabolism; milk; milk composition; obesity; olive oil; olives; overeating; progeny; pups; rats; soybean oil; soybeans; triacylglycerols; weaning
Abstract:
... Some oils considered healthy are commonly used, even in critical periods of life. We studied the effects of maternal supplementation with soybean, olive, fish and coconut oils during lactation on the male rat offspring metabolism. Dams and pups were divided: Soybean oil (control); Olive Oil (OO); Fish Oil (FO) and Coconut Oil (CO). Dams received the oils through gavage (0.5 g/kg BW) during lactati ...
DOI:
10.1016/j.jff.2018.06.027

17. Does gamma-aminobutyric acid have a potential role on the antihypertensive effect of fermented milk with Lactococcus lactis NRRL B-50571?

Author:
Beltrán-Barrientos, Lilia María; Estrada-Montoya, Carmen; Reyes-Díaz, Ricardo; Hernández-Mendoza, Adrián; González-Córdova, Aarón Fernando; Vallejo-Córdoba, Belinda
Source:
Journal of functional foods 2018 v.48 pp. 297-301
ISSN:
1756-4646
Subject:
Lactococcus lactis; animal disease models; antagonists; antihypertensive effect; blood pressure; fermentation; fermented milk; gamma-aminobutyric acid; hypertension; metabolites; milk; rats; receptors; water solubility
Abstract:
... Gamma-aminobutyric acid (GABA) may be generated during milk fermentation, and this metabolite may have antihypertensive effect in spontaneously hypertensive rats (SHR). We determined the potential role of GABA on the antihypertensive effect of the water-soluble extract obtained from fermented milk with Lactococcus lactis NRRL B-50571 (WSE-FM). First, GABA concentration from WSE-FM was analyzed. Th ...
DOI:
10.1016/j.jff.2018.07.016

18. Donkey milk lysozyme ameliorates dextran sulfate sodium-induced colitis by improving intestinal barrier function and gut microbiota composition

Author:
Jiang, Lun; Lv, Jiayi; Liu, Jingwen; Hao, Xianghui; Ren, Fazheng; Guo, Huiyuan
Source:
Journal of functional foods 2018 v.48 pp. 144-152
ISSN:
1756-4646
Subject:
lysozyme; intestinal microorganisms; ass milk; dextran sulfate; colon; inflammation; interleukin-13; mice; tumor necrosis factor-alpha; probiotics; myeloperoxidase; active sites; oral administration; colitis; binding capacity; weight loss; bacteria; X-radiation
Abstract:
... Donkey milk lysozyme (DML) is a potential therapeutic agent for inflammatory bowel disease (IBD), while the mechanism remains obscure. Here, we reported that DML ameliorated weight loss, colon damage and mucosal inflammation in colitis mice. Additionally, DML increased the expression of occluding and zonula occludens-1, and reduced that of claudin-2, thus improving mechanical barrier function. It ...
DOI:
10.1016/j.jff.2018.07.005

19. Edible bird’s nest improves motor behavior and protects dopaminergic neuron against oxidative and nitrosative stress in Parkinson’s disease mouse model

Author:
Yew, Mei Yeng; Koh, Rhun Yian; Chye, Soi Moi; Othman, Iekhsan; Soga, Tomoko; Parhar, Ishwar; Ng, Khuen Yen
Source:
Journal of functional foods 2018 v.48 pp. 576-585
ISSN:
1756-4646
Subject:
Parkinson disease; animal models; antioxidants; brain; glutathione peroxidase; lipid peroxidation; locomotion; mice; neuroglia; neurons; neuroprotective effect; nitric oxide; oral administration
Abstract:
... Parkinson’s disease (PD) is a neurological disorder originated from the death of dopaminergic neurons in the midbrain. Evidences showed that oxidative and nitrosative stress play a central role in neurodegeneration. In this study, we examine the neuroprotective effects of EBN (20 mg/kg and 100 mg/kg) in 6-hydroxydopamine (6-OHDA)-treated C57BL/6J mice. Twenty eight days of EBN oral administration ...
DOI:
10.1016/j.jff.2018.07.058

20. Effects of anthocyanins from the fruit of Lycium ruthenicum Murray on intestinal microbiota

Author:
Yan, Yamei; Peng, Yujia; Tang, Jilong; Mi, Jia; Lu, Lu; Li, Xiaoying; Ran, Linwu; Zeng, Xiaoxiong; Cao, Youlong
Source:
Journal of functional foods 2018 v.48 pp. 533-541
ISSN:
1756-4646
Subject:
Bifidobacterium; Clostridium; Dialister; Lycium ruthenicum; Megamonas; Prevotella; anthocyanins; butyric acid; fermentation; fruits; in vitro digestion; intestinal microorganisms; inulin; saliva; small intestine
Abstract:
... Simulated digestion and fermentation in vitro by human intestinal microbiota of anthocyanins from Lycium ruthenicum Murray were investigated in this study. It was shown that the anthocyanins from L. ruthenicum were not digested in simulated saliva, gastric and small intestine fluids. Under fermentation in vitro, the anthocyanins from L. ruthenicum interacted with intestinal microbiota and promoted ...
DOI:
10.1016/j.jff.2018.07.053

21. Effects of omega-3 fatty acids and sugar on attention in the spontaneously hypertensive rat

Author:
Hauser, Joachim; Stollberg, Ewelina; Reissmann, Andreas; Kaunzinger, Ivo; Lange, Klaus W.
Source:
Journal of functional foods 2018 v.48 pp. 676-681
ISSN:
1756-4646
Subject:
animal disease models; cognition; diet; glucose; hypertension; omega-3 fatty acids; progeny; rats; sucrose
Abstract:
... Dietary omega-3 fatty acids and sugar may potentially influence cognition. The effects of reduced omega-3 PUFA and high sugar intakes in rats on attentional functions were investigated. Two groups of rat dams and their offspring were fed either an omega-3 adequate or an omega-3 deficient diet, both with high sucrose/glucose content. A control group was fed an omega-3 adequate diet containing stand ...
DOI:
10.1016/j.jff.2018.07.057

22. Effects of oral administration of peptides with low molecular weight from Alaska Pollock (Theragra chalcogramma) on cutaneous wound healing

Author:
Yang, Tingting; Zhang, Kai; Li, Bafang; Hou, Hu
Source:
Journal of functional foods 2018 v.48 pp. 682-691
ISSN:
1756-4646
Subject:
Gadus chalcogrammus; collagen; ingredients; models; molecular weight; mothers against decapentaplegic homolog proteins; oral administration; protein supplements; rats; signal transduction; tensile strength; tissue repair; transforming growth factor beta 1
Abstract:
... Protein supplements play an important role in wound healing. The effect of collagen peptide (PCP) and flesh protein peptide (FPP) from Alaska Pollock on wound healing was investigated. The molecular weight distributions of PCP and FPP were in a range of 430–1000 Da and 100–1000 Da, respectively. Compared to vehicle group, the wound healing activities in PCP and FPP were significantly enhanced, whi ...
DOI:
10.1016/j.jff.2018.08.006

23. Effects of prebiotic inulin addition to low- or high-fat diet on maternal metabolic status and neonatal traits of offspring in a pregnant sow model

Author:
Zhou, Pan; Wang, Yongsheng; Li, Shuang; Zhao, Yang; Deng, Kai; Chao, Dandan; Jin, Chao; Zhuo, Yong; Che, Lianqiang; Li, Jian; Lin, Yan; Xu, Shengyu; Feng, Bin; Fang, Zhengfeng; Wu, De
Source:
Journal of functional foods 2018 v.48 pp. 125-133
ISSN:
1756-4646
Subject:
bile acids; blood lipids; blood serum; body mass index; butyrates; calcium; digestibility; excretion; glucose tolerance; high fat diet; insulin resistance; inulin; lipid composition; models; piglets; prebiotics; pregnancy; progeny; propionic acid; sows
Abstract:
... The effects of adding inulin to low- or high-fat diet on the metabolic status and nutrient digestibility in gestating sows and the neonatal traits of their offspring were examined. Sixty sows were allocated to a 2 × 2 factorial treatment design with levels of inulin (0% or 1.5%) and fat (0% or 5%) addition as the fixed factors during gestation. Inulin supplementation resulted in the following: imp ...
DOI:
10.1016/j.jff.2018.07.004

24. Encapsulation of natural active compounds, enzymes, and probiotics for fruit juice fortification, preservation, and processing: An overview

Author:
Ephrem, Elissa; Najjar, Amal; Charcosset, Catherine; Greige-Gerges, Hélène
Source:
Journal of functional foods 2018 v.48 pp. 65-84
ISSN:
1756-4646
Subject:
active ingredients; anti-infective agents; beverages; encapsulation; enzymes; fruit juices; lactose free diet; probiotics; raw fruit; shelf life; solubility; vitamins
Abstract:
... Fruit juices are low-fat, non-alcoholic, lactose-free, and nutritious beverages that are highly desired by consumers. However, fruit juices undergo microbial, enzymatic, and chemical deterioration, which shortens their shelf-life. The demand for healthy fresh fruit juice has encouraged the use of natural agents (such as antimicrobials, vitamins, anti-browning agents, and probiotics) for the protec ...
DOI:
10.1016/j.jff.2018.06.021

25. Endogenousn-3polyunsaturated fatty acids prevent azoxymethane-induced colon tumorigenesis in mice fed a high-fat diet

Author:
Yao, An-Jun; Chen, Jia-Hui; Xu, Yan; Zhang, Zhuang-Wei; Zou, Zu-Quan; Yang, Hai-Tao; Hua, Qi-Hang; Zhao, Jin-Shun; Kang, Jing-Xuan; Zhang, Xiao-Hong
Source:
Journal of functional foods 2018 v.48 pp. 439-447
ISSN:
1756-4646
Subject:
carcinogenesis; cell proliferation; colon; colorectal neoplasms; high fat diet; mice; neoplasm cells; omega-3 fatty acids; polyunsaturated fatty acids; protective effect; signal transduction
Abstract:
... Literature suggests important roles of a high-fat diet (HFD) in tumour development, but the underlying mechanisms remain poorly understood. This study assessed the protective effect of n-3 polyunsaturated fatty acids (PUFAs) on HFD-enhanced colon tumours and the underlying mechanism. WT mice were fed a normal fat diet or HFD and Fat-1 mice were fed a HFD for 22 weeks. For weeks 1–6, all mice were ...
DOI:
10.1016/j.jff.2018.07.042

26. Enhanced estrogenic effects of biotransformed soy extracts

Author:
de Ávila, Amanda Rejane Alves; de Queirós, Lívia Dias; Lopes, Danielle Branta; Barin, Clara Guido; Ueta, Tatiane Mayumi; Ruiz, Ana Lúcia Tasca Gois; Macedo, Gabriela Alves; Macedo, Juliana Alves
Source:
Journal of functional foods 2018 v.48 pp. 117-124
ISSN:
1756-4646
Subject:
bioprocessing; biotransformation; cell lines; estrogenic properties; functional foods; hormone replacement therapy; human health; in vitro studies; intestinal microorganisms; isoflavones; menopause; metabolites; polyphenols; risk; soymilk; tannase; women
Abstract:
... Soy isoflavones have been associated with several beneficial effects to human health including estrogenic action. Due to the risks associated with pharmaceutical hormone replacement therapy, soy extracts rich in isoflavones and metabolites appear as a safe alternative for menopausal women. This study aimed to improve the process conditions for biotransformation of soymilk polyphenols by tannase to ...
DOI:
10.1016/j.jff.2018.06.026

27. Enhancement of cognitive functions by rice bran extract in a neuroinflammatory mouse model via regulation of PPARγ

Author:
Mostafa, A.O.; Abdel-Kader, R.M.; Heikal, O.A.
Source:
Journal of functional foods 2018 v.48 pp. 314-321
ISSN:
1756-4646
Subject:
animal models; antagonists; brain; cognition; inflammation; memory; mice; neurodegenerative diseases; peroxisome proliferator-activated receptors; polyunsaturated fatty acids; rice bran oil
Abstract:
... Activation of the peroxisome proliferator-activated receptor gamma (PPARγ), has been recently demonstrated to attenuate inflammatory response and improve cognitive dysfunction in neurodegenerative diseases. RBE is rich in polyunsaturated fatty acids, which were recently considered as new PPARγ modulators. Accordingly, the effect of RBE on memory and cognition in a neuroinflammatory mouse model was ...
DOI:
10.1016/j.jff.2018.07.023

28. Evaluating the behaviour of curcumin nanoemulsions and multilayer nanoemulsions during dynamic in vitro digestion

Author:
Silva, Hélder D.; Poejo, Joana; Pinheiro, Ana C.; Donsì, Francesco; Serra, Ana Teresa; Duarte, Catarina M.M.; Ferrari, Giovanna; Cerqueira, Miguel A.; Vicente, António A.
Source:
Journal of functional foods 2018 v.48 pp. 605-613
ISSN:
1756-4646
Subject:
alginates; antioxidant activity; bioactive compounds; bioavailability; chitosan; curcumin; digestibility; electrolytes; free fatty acids; functional foods; gastrointestinal system; in vitro digestion; lipid metabolism; lipophilicity; nanoemulsions; nanotechnology; obesity; satiety; sodium dodecyl sulfate; toxicity; toxicity testing
Abstract:
... Nanoemulsions can be used to improve the bioaccessibility of lipophilic bioactive compounds, such as curcumin, being their behaviour highly influenced by their interfacial properties. The effect of chitosan and alginate layers’ deposition on curcumin nanoemulsions’ behaviour during in vitro digestion was evaluated using a dynamic gastrointestinal system. Results showed that polyelectrolyte layers’ ...
DOI:
10.1016/j.jff.2018.08.002

29. Exploring inhibitory mechanism of gallocatechin gallate on a-amylase and a-glucosidase relevant to postprandial hyperglycemia

Author:
Wu, Xiaqing; Ding, Huafang; Hu, Xing; Pan, Junhui; Liao, Yijing; Gong, Deming; Zhang, Guowen
Source:
Journal of functional foods 2018 v.48 pp. 200-209
ISSN:
1756-4646
Subject:
acarbose; active sites; alpha-amylase; alpha-glucosidase; amino acids; diabetes; enzyme activity; enzyme inhibition; enzyme inhibitors; epigallocatechin; functional foods; hyperglycemia; patients
Abstract:
... The postprandial hyperglycemia of diabetic patients is associated with a-amylase and a-glucosidase, searching safer enzyme inhibitors and deciphering their inhibition mechanism are important. In this study, gallocatechin gallate (GCG) was found to exert strong inhibition on α-amylase and α-glucosidase in the mixed-type and non-competitive manners, respectively. GCG could bind with α-amylase and α- ...
DOI:
10.1016/j.jff.2018.07.022

30. Extracts of Cerbera manghas L. effectively inhibit the viability of glioblastoma cell lines and their cancer stemloids in vitro and in mouse xenograft model

Author:
Tsai, Jui-Cheng; Liu, Wen-Shan; Tseng, Ying-Ting; Lam, Hoi-Ian; Chen, Szu-Ying; Fang, Cheng-Li; Tong, Tien-Soung; Lai, Yun-Ju
Source:
Journal of functional foods 2018 v.48 pp. 283-296
ISSN:
1756-4646
Subject:
Cerbera manghas; apoptosis; cell lines; mice; models; neoplasms; prognosis; stem cells; viability
Abstract:
... Glioblastoma multiforme (GBM), a highly recurrent malignant disease, is a grade IV glioma with poor prognosis. Glioblastoma stem cells (GSCs) are the new potential target for GBM intervention. To develop an improved treatment by targeting GSCs, we identified neriifolin, an active principle in extracts of Cerbera manghas L., as an effective inhibitor for the growth and migration of GBM cell lines a ...
DOI:
10.1016/j.jff.2018.07.017

31. Ferulic acid inhibits advanced glycation end products (AGEs) formation and mitigates the AGEs-induced inflammatory response in HUVEC cells

Author:
Liu, Jian-li; He, Yong-lin; Wang, Shuai; He, Yin; Wang, Wei-yu; Li, Qi-jiu; Cao, Xiang-yu
Source:
Journal of functional foods 2018 v.48 pp. 19-26
ISSN:
1756-4646
Subject:
advanced glycation end products; atherosclerosis; caspase-1; ferulic acid; gene expression; glycation; human umbilical vein endothelial cells; inflammation; intercellular adhesion molecule-1; interleukin-18; interleukin-1beta; messenger RNA; mitogen-activated protein kinase; molecular models; patients; protective effect; signal transduction; spectroscopy; transcription factor NF-kappa B; vascular cell adhesion molecules
Abstract:
... Advanced glycation end products (AGEs) are complex and heterogeneous compounds, which play an important role in diabetic-related vascular complications, especially in atherosclerosis. In this study, the effects of ferulic acid (FA) on glucose-related protein glycation were investigated in vitro by various spectroscopic techniques and molecular docking methods. In order to study the protective effe ...
DOI:
10.1016/j.jff.2018.06.024

32. Fucoidan alleviates dyslipidemia and modulates gut microbiota in high-fat diet-induced mice

Author:
Liu, Min; Ma, Lin; Chen, Qichao; Zhang, Pengyu; Chen, Chao; Jia, Lilin; Li, Huajun
Source:
Journal of functional foods 2018 v.48 pp. 220-227
ISSN:
1756-4646
Subject:
Bacteroidetes; Staphylococcus; Streptococcus; Undaria pinnatifida; bioactive properties; blood serum; cholesterol; fucoidan; functional foods; high fat diet; hyperlipidemia; intestinal microorganisms; lactic acid bacteria; liver; mice; proteins; ribosomal RNA; sequence analysis
Abstract:
... Fucoidan is a functional food that possesses various biological activities. This study aims to determine the effects of fucoidan from Undaria pinnatifida on gut microbiota and dyslipidemia in BALB/c mice. In vitro, fucoidan could support the growth of three lactic acid bacteria strains. The test groups with high fat diet (HFD) were gavaged with fucoidan at a dose of 50 mg/kg/day or 100 mg/kg/day f ...
DOI:
10.1016/j.jff.2018.07.006

33. Fucoxanthin ameliorates hyperglycemia, hyperlipidemia and insulin resistance in diabetic mice partially through IRS-1/PI3K/Akt and AMPK pathways

Author:
Zhang, Yiping; Xu, Wen; Huang, Xiaoqiang; Zhao, Youqin; Ren, Qiangqiang; Hong, Zhuan; Huang, Mingqing; Xing, Xia
Source:
Journal of functional foods 2018 v.48 pp. 515-524
ISSN:
1756-4646
Subject:
animal disease models; blood glucose; blood lipids; carnitine palmitoyltransferase; diabetes; diet; drugs; fatty-acid synthase; functional foods; glucokinase; glucose; glucose transporters; glycogen; glycogen (starch) synthase; histology; hyperglycemia; hyperlipidemia; insulin resistance; lipid metabolism; liver; messenger RNA; mice; peroxisome proliferator-activated receptors; skeletal muscle
Abstract:
... Fucoxanthin has potential anti-diabetic activities, but its precise effects and underlying mechanisms remain unclear. In this study, C57BL/KsJ-db/db mice were fed diets containing fucoxanthin (0.2% and 0.4%, w/w) for 6 weeks. Results showed dietary fucoxanthin significantly improved glucose/lipid metabolism and insulin resistance, and prevented pancreatic histological changes in db/db mice. Moreov ...
DOI:
10.1016/j.jff.2018.07.048

34. Gastroprotective property of Pseudocydonia sinensis fruit jelly on the ethanol-induced gastric lesions in rats

Author:
Hamauzu, Yasunori; Kishida, Hiyo; Yamazaki, Nozomi
Source:
Journal of functional foods 2018 v.48 pp. 275-282
ISSN:
1756-4646
Subject:
Pseudocydonia sinensis; binding capacity; boiling; fruits; gastric mucosa; jellies; pectins; polymerization; procyanidins; rats; synergism; tumor necrosis factor-alpha
Abstract:
... The gastroprotective activity of Chinese quince (Pseudocydonia sinensis) jellies made from boiling water extracts of the fruit were investigated. Pre-administration of the jellies to rats protected gastric tissues against HCl/ethanol-induced gastric injury, demonstrated by a reduction in the gastric lesion index and TNF-α levels. The effect was stronger in the jellies made from extracts obtained b ...
DOI:
10.1016/j.jff.2018.07.026

35. Green coffee bean extract and 5-O-caffeoylquinic acid regulate fat metabolism in Caenorhabditis elegans

Author:
Farias-Pereira, Renalison; Oshiro, Jordan; Kim, Kee-Hong; Park, Yeonhwa
Source:
Journal of functional foods 2018 v.48 pp. 586-593
ISSN:
1756-4646
Subject:
Caenorhabditis elegans; chlorogenic acid; coffee beans; energy; homeostasis; lipogenesis; mammals; models; transcription factors; triacylglycerols; weight loss
Abstract:
... Green coffee bean extract (GCBE) and chlorogenic acids are known to be associated with weight loss. 5-O-caffeoylquinic acid (5-CQA) is the main form of chlorogenic acid in GCBE. This study investigated GCBE and 5-CQA’s molecular mechanisms on fat metabolism using Caenorhabditis elegans as a model system. Treatment of GCBE or 5-CQA reduced triglycerides level by 29% and 23%, respectively, compared ...
DOI:
10.1016/j.jff.2018.07.049

36. Hepatoprotective effect of flavonoid-enriched fraction from Cyclocarya paliurus leaves on LPS/D-GalN-induced acute liver failure

Author:
Hu, Wen-Bing; Ouyang, Ke-Hui; Wu, Guo-Qiang; Chen, Hui; Xiong, Lei; Liu, Xin; Wang, Ning; Wang, Wen-Jun
Source:
Journal of functional foods 2018 v.48 pp. 337-350
ISSN:
1756-4646
Subject:
B-lymphocytes; Cyclocarya paliurus; alanine transaminase; apoptosis; aspartate transaminase; chemical composition; cytokines; functional foods; hepatoprotective effect; kaempferol; leaves; liver failure; mass spectrometry; mitochondria; mortality; oxidative stress; quercetin; reactive oxygen species; transcription factor NF-kappa B; ultra-performance liquid chromatography
Abstract:
... This study aimed to investigate the chemical composition and hepatoprotective effect of flavonoid fraction from Cyclocarya paliurus leaves (CPF) on the lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced acute liver failure (ALF). UPLC-MS analysis revealed that CPF mainly contained quercetin-3-O-glycoside, quercetin-3-O-rhamnoside, kaempferol-3-O-rhamnoside, quercetin and kaempferol. CPF treat ...
DOI:
10.1016/j.jff.2018.07.031

37. Hibiscus sabdariffa polyphenol-enriched extract inhibits colon carcinoma metastasis associating with FAK and CD44/c-MET signaling

Author:
Huang, Chi-Chou; Hung, Chia-Hung; Chen, Ching-Chun; Kao, Shao-Hsuan; Wang, Chau-Jong
Source:
Journal of functional foods 2018 v.48 pp. 542-550
ISSN:
1756-4646
Subject:
Hibiscus sabdariffa; animal models; bioactive properties; cell movement; colorectal neoplasms; cytoskeleton; drug therapy; humans; liver; metastasis; neoplasm cells; patients
Abstract:
... Hibiscus sabdariffa extracts have multiple bioactivities. Here, we aimed to investigate the anti-metastatic effects of a polyphenol-enriched extract of Hibiscus sabdariffa (HPE) on colon cancer cells. We observed that HPE (≤3 mg/mL) significantly inhibited the cell migration and invasion of human colorectal cancer (CRC) cell DLD-1. In parallel, HPE altered cytoskeletal structure, downregulated the ...
DOI:
10.1016/j.jff.2018.07.055

38. Hypocholesterolemic effect of Spirulina platensis (SP) fortified functional soy yogurts on diet-induced hypercholesterolemia

Author:
Sengupta, Samadrita; Koley, Hemanta; Dutta, Shanta; Bhowal, Jayati
Source:
Journal of functional foods 2018 v.48 pp. 54-64
ISSN:
1756-4646
Subject:
Arthrospira platensis; alanine transaminase; alkaline phosphatase; animal models; antioxidants; aspartate transaminase; blood serum; catalase; cholesteremic effect; cholesterol; functional foods; gamma-glutamyltransferase; glutathione; hypercholesterolemia; liver function; mice; microalgae; soymilk; superoxide dismutase; thiobarbituric acid-reactive substances; yogurt
Abstract:
... The present study was designed to investigate in-vivo cholesterol lowering effect of soy yogurt fortified with Spirulina platensis. The enrichment of soy yogurt with Spirulina platensis was performed with its addition in concentrations of 0.5%, 1.0% and 1.5% of soy milk. A hypercholesterolemic mice model was established to examine the effects of microalgae supplemented soy yogurt on hypercholester ...
DOI:
10.1016/j.jff.2018.07.007

39. iCellular uptake of [1–9-NαC]-linusorb B2 and [1–9-NαC]-linusorb B3 isolated from flaxseed, and their antitumor activities in human gastric SGC-7901 cells

Author:
Zou, Xian-Guo; Hu, Jiang-Ning; Li, Jing; Yang, Jian-Yuan; Du, Ying-Xue; Yu, Yan-Fang; Deng, Ze-Yuan
Source:
Journal of functional foods 2018 v.48 pp. 692-703
ISSN:
1756-4646
Subject:
antineoplastic activity; apoptosis; caspase-3; caspase-8; caspase-9; cytochrome c; death domain receptors; human cell lines; intestinal absorption; isoleucine; linseed; membrane potential; methionine; mitochondrial membrane
Abstract:
... The aim of this study was to investigate the cellular uptake and antitumor activity of 2 different structural flaxseed orbitides ([1–9-NαC]-linusorb B2 containing methionine residue and [1–9-NαC]-linusorb B3 containing isoleucine residue) in SGC-7901 cells as well as its underlying molecule mechanism. Results showed that the absorption efficiency of [1–9-NαC]-linusorb B3 was higher than that of [1 ...
DOI:
10.1016/j.jff.2018.08.008

40. Influence of probiotics, prebiotics, synbiotics and bioactive phytochemicals on the formulation of functional yogurt

Author:
Fazilah, Nurul Farhana; Ariff, Arbakariya B.; Khayat, Mohd Ezuan; Rios-Solis, Leonardo; Halim, Murni
Source:
Journal of functional foods 2018 v.48 pp. 387-399
ISSN:
1756-4646
Subject:
functional foods; healthy diet; ingredients; longevity; nutrients; phytopharmaceuticals; prebiotics; probiotics; sensory properties; yogurt
Abstract:
... The new concept of functional foods has led to the varieties in the production of foods that deliver not only basic nutrition, but can also warrant good health and longevity. Yogurt has become one of the prevalent choices and considered as a healthy food since it provides excellent sources of essential nutrients. As the popularity of yogurt continues to grow, manufacturers and scientists continuou ...
DOI:
10.1016/j.jff.2018.07.039

41. Influence of zinc deficiency and supplementation on NK cell cytotoxicity

Author:
Rolles, Benjamin; Maywald, Martina; Rink, Lothar
Source:
Journal of functional foods 2018 v.48 pp. 322-328
ISSN:
1756-4646
Subject:
cytotoxicity; human cell lines; interleukin-2; natural killer cells; nutrient deficiencies; zinc
Abstract:
... Knowledge about the role of zinc on natural killer (NK) cell activity and function is limited and needs further instigation. Hence, in this study, the influence of interleukin (IL)-1, IL-2, zinc, and the zinc-chelator N,N,N′,N′-tetrakis(2-pyridylmethyl)ethane-1,2-diamine (TPEN) on the human NK cell line (YTS cell line) and primary NK cells were examined. We mainly focused on NK cell killing activi ...
DOI:
10.1016/j.jff.2018.07.027

42. Inhibitory effect of astaxanthin on pancreatic lipase with inhibition kinetics integrating molecular docking simulation

Author:
Du, Xiping; Bai, Manli; Huang, Ying; Jiang, Zedong; Chen, Feng; Ni, Hui; Li, Qingbiao
Source:
Journal of functional foods 2018 v.48 pp. 551-557
ISSN:
1756-4646
Subject:
active sites; astaxanthin; dose response; enzyme activity; food industry; functional foods; kinetics; molecular models; obesity; triacylglycerol lipase
Abstract:
... Astaxanthin is a natural pigment that possesses benefit potentials to prevent obesity, however, its underlying mechanism is not clarified. In the current study, Phaffia rhodozyma astaxanthin was prepared and its inhibitory effect on pancreatic lipase was evaluated. The results showed that astaxanthin significantly inhibited the activity of pancreatic lipase in a dose-dependent manner within the te ...
DOI:
10.1016/j.jff.2018.07.045

43. Inulin as microencapsulating agent improves physicochemical properties of spray-dried aspalathin-rich green rooibos (Aspalathus linearis) extract with α-glucosidase inhibitory activity

Author:
Miller, Neil; De Beer, Dalene; Aucamp, Marique; Malherbe, Christiaan J.; Joubert, Elizabeth
Source:
Journal of functional foods 2018 v.48 pp. 400-409
ISSN:
1756-4646
Subject:
Aspalathus linearis; acarbose; air temperature; alpha-glucosidase; enzyme inhibition; functional foods; glycemic index; ingredients; inulin; maltodextrins; microencapsulation; response surface methodology; spray drying; wettability
Abstract:
... Limiting aspalathin degradation during spray-drying of green rooibos extract (GRE) is crucial to produce a functional food ingredient with antidiabetic properties. Retention of aspalathin in a GRE-inulin mixture (1:1, m/m) was not affected by process conditions (inlet air temperature, feed concentration and feed flow rate) tested according to a central composite design. Powder yield could subseque ...
DOI:
10.1016/j.jff.2018.07.028

44. Isomaltulose: Recent evidence for health benefits

Author:
Shyam, Sangeetha; Ramadas, Amutha; Chang, Sui Kiat
Source:
Journal of functional foods 2018 v.48 pp. 173-178
ISSN:
1756-4646
Subject:
chronic diseases; cognition; fructose; glucose; glycemic index; isomaltulose; neoplasms; prebiotics; sucrose
Abstract:
... Isomaltulose (IM) is a naturally occurring disaccharide composed of alpha-1,6-linked glucose and fructose monomers. IM is gaining interest as an alternative sweetener to sucrose primarily because of its low glycaemic index (GI) properties. Low GI has been implicated in the prevention and management of chronic diseases such as cardio-metabolic diseases and cancers. The low glycaemic potential of IM ...
DOI:
10.1016/j.jff.2018.07.002

45. Jaboticaba berry peel intake increases short chain fatty acids production and prevent hepatic steatosis in mice fed high-fat diet

Author:
Batista, Ângela Giovana; da Silva-Maia, Juliana Kelly; Mendonça, Monique Culturato P.; Soares, Edilene Siqueira; Lima, Glaucia Carielo; Bogusz Junior, Stanislau; da Cruz-Höfling, Maria Alice; Maróstica Júnior, Mário Roberto
Source:
Journal of functional foods 2018 v.48 pp. 266-274
ISSN:
1756-4646
Subject:
Plinia cauliflora; adipose tissue; cytokines; excretion; fatty liver; high fat diet; hyperlipidemia; inflammation; intestinal microorganisms; liver; messenger RNA; metabolites; mice; models; obesity; oxidation; short chain fatty acids; triacylglycerols; weight gain
Abstract:
... In this study, a preventive model was proposed to check whether the intake of Myrciaria jaboticaba berry peel (MJP) could avoid harmful effects caused by a high-fat diet. The intake of the high-fat diet supplemented with MJP (HM mice) down-regulated pro-inflammatory cytokines in adipose tissue and prevented adipose tissue growth and accumulation. In addition, the intake of the high-fat diet supple ...
DOI:
10.1016/j.jff.2018.07.020

46. Konjac glucomannan improves hyperuricemia through regulating xanthine oxidase, adenosine deaminase and urate transporters in rats

Author:
Zhang, Yuan; Deng, Liling; Wu, Chunmei; Zheng, Lianji; Zhong, Geng
Source:
Journal of functional foods 2018 v.48 pp. 566-575
ISSN:
1756-4646
Subject:
adenosine deaminase; animal models; blood serum; creatinine; excretion; gene expression; gene expression regulation; hyperuricemia; kidneys; konjac mannan; liver; messenger RNA; protein synthesis; rats; transporters; urea nitrogen; uric acid; xanthine oxidase
Abstract:
... To develop a more effective and safer treatment for Hyperuricemia (HUA), this research investigated the anti-hyperuricemic mechanism of KGM from the perspectives of uric acid (UA) production and excretion in rat model. After four-week experiment, KGM at 168 mg/kg did best in reducing serum UA level. The mechanism of KGM improving HUA was related to its inhibitory capacity to the activities and mRN ...
DOI:
10.1016/j.jff.2018.07.062

47. Lactobacillus rhamnosus and Lactobacillus delbrueckii ameliorate the expression of miR-155 and miR-181a in SLE patients

Author:
Vahidi, Zohreh; Samadi, Morteza; Mahmoudi, Mahmoud; RezaieYazdi, Zahra; Sahebari, Maryam; Tabasi, Nafiseh; Esmaeili, Seyed-Alireza; Sahebkar, Amirhossein; Rastin, Maryam
Source:
Journal of functional foods 2018 v.48 pp. 228-233
ISSN:
1756-4646
Subject:
Lactobacillus delbrueckii; Lactobacillus rhamnosus; autoantibodies; complementary DNA; immune response; lupus erythematosus; microRNA; mononuclear leukocytes; patients; probiotics; quantitative polymerase chain reaction
Abstract:
... Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease characterized by the production of autoantibodies and activated immune cells against self-antigens. Probiotics are known to possess anti-inflammatory and modulatory effects on the immune responses. In this study, we evaluated the effect of probiotics Lactobacillus rhamnosus and Lactobacillus delbrueckii on the expressi ...
DOI:
10.1016/j.jff.2018.07.025

48. Melatonin increases magnesium concentrations in white adipose tissue and pancreas of diabetic obese rats

Author:
Navarro-Alarcon, Miguel; Villalón, Marina; Jiménez, Cecilia; Quesada-Granados, Javier; Agil, Ahmad
Source:
Journal of functional foods 2018 v.48 pp. 167-172
ISSN:
1756-4646
Subject:
adipokines; bioactive compounds; carbohydrate metabolism; diabetes; functional foods; glucose; gonads; homeostasis; insulin resistance; magnesium; melatonin; obesity; omentum; oxidative stress; pancreas; rats; white adipose tissue
Abstract:
... Melatonin is a natural bioactive compound, whose intake by obese diabetic Zucker (ZDF) rats improves this pathology. Hypomagnesaemia has also been observed in diabetes, and magnesium (Mg) is known to play an essential role in carbohydrate metabolism. In this study we have determined the effect of melatonin intake on Mg concentrations in white adipose tissues and organs in ZDF rats. This study reve ...
DOI:
10.1016/j.jff.2018.07.018

49. Metals in food products with rising consumption (brewer’s yeast, wheat bran, oat bran, sesame seeds, flaxseeds, chia seed). A nutritional and toxicological evaluation

Author:
Rubio, Carmen; González-Weller, Dailos; Caballero, José M.; Romano, Ana R.; Paz, Soraya; Hardisson, Arturo; Gutiérrez, Ángel J.; Revert, Consuelo
Source:
Journal of functional foods 2018 v.48 pp. 558-565
ISSN:
1756-4646
Subject:
aluminum; calcium; food intake; iron; linseed; manganese; novel foods; oat bran; risk; seeds; sesame seed; toxicity testing; wheat bran; zinc
Abstract:
... Brewer’s yeast, sesame seeds, wheat bran, oat bran, flaxseeds and chia seeds have gained popularity. Twenty metals were determined by ICP-OES for a nutritional and toxicological evaluation of the metal content of these foods. K is the most abundant macroelement in brewer’s yeast (4959 mg/kg), followed by Ca in sesame seeds (4349 mg/kg). Regarding the micronutrients, the Zn level in brewer’s yeast ...
DOI:
10.1016/j.jff.2018.07.051

50. Novel molecular mechanisms by which ginger extract reduces the inflammatory stress in TNFα – activated human endothelial cells; decrease of Ninjurin-1, TNFR1 and NADPH oxidase subunits expression

Author:
Toma, Laura; Raileanu, Mina; Deleanu, Mariana; Stancu, Camelia S.; Sima, Anca V.
Source:
Journal of functional foods 2018 v.48 pp. 654-664
ISSN:
1756-4646
Subject:
NAD(P)H oxidase (H2O2-forming); NADP (coenzyme); adhesion; advanced glycation end products; antioxidants; atherosclerosis; cell adhesion; chemokine CCL2; endothelial cells; ginger; heme oxygenase (biliverdin-producing); human cell lines; inflammation; mechanism of action; monocytes; oxidative stress; transcription factor NF-kappa B; tumor necrosis factor-alpha; vascular cell adhesion molecules
Abstract:
... Dysfunction of endothelial cells (EC) is important for atherosclerosis progression. The aim of this study was to evaluate the potential of ginger extract (GEx), 6-gingerol (6-G) and 6-shogaol (6-Sh) to reverse EC dysfunction and to investigate its mechanism of action, using cultured human EC incubated with TNFα. The results showed that GEx decreases monocyte chemoattractant protein-1, vascular cel ...
DOI:
10.1016/j.jff.2018.08.011