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- Dias, Camila C.A.; Moraes, Mauro P.; Diaz-San Segundo, Fayna; De los Santos, Teresa; Grubman, Marvin J.
- Journal of interferon & cytokine research 2011 v.31 no.2 pp. 227
- swine; Foot-and-mouth disease virus; serotypes; foot-and-mouth disease; immunity; vaccination; live vaccines; genetic vectors; Adenoviridae; genes; interferons; intramuscular injection
- ... Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals. Current inactivated vaccines require approximately 7 days to induce protection, but before this time vaccinated animals remain susceptible to disease. Previously, we demonstrated that intramuscular (IM) inoculation of a replication-defective human adenovirus type 5 (Ad5) vector containing a porcine int ...