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- Sahariah, Priyanka; Snorradóttir, Bergthóra S.; Hjálmarsdóttir, Martha Á.; Sigurjónsson, Ólafur E.; Másson, Már
- Journal of materials chemistry B 2016 v.4 no.27 pp. 4762-4770
- computer software, etc ; Escherichia coli; Gram-negative bacteria; Gram-positive bacteria; Staphylococcus aureus; acetylation; antibacterial properties; biopolymers; chitosan; erythrocytes; experimental design; hemolysis; humans; models; quantitative structure-activity relationships; solubility; Show all 16 Subjects
- ... Experimental design approach was successfully used to guide the synthesis and determine the structure–activity relationship for antimicrobial derivatives of the biopolymer chitosan. Specialized software with D-optimal design capabilities was used to create a library of chitosan derivatives with optimal structural variation in order to conduct a detailed investigation of the structure–activity rela ...