Author: "Chen, Yi-ping" / Journal: Journal of materials chemistry B / Subject: superoxide dismutase and Western blotting

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Author:: Chen, Yi-Ping, et al. ; Fang, Ya-Cheng; Chen, Chien-Tsu; Lin, Tien-Sung; Mou, Chung-Yuan; Show all 5 Authors
Source:: Journal of materials chemistry B 2013 v.1 no.44 pp. 6042-6052
ISSN:: 2050-7518
Subject:: Western blotting; antioxidant enzymes; catalytic activity; cell cycle; cell viability; copper; encapsulation; flow cytometry; fluorescein; human cell lines; isothiocyanates; nanocarriers; nanoparticles; paraquat; perchlorates; porous media; silica; superoxide dismutase; zinc
Abstract:: ... A new copper zinc complex (CZpbi), [(bipyridinyl)₂Cu-μ-pbi-Zn(pbi)](ClO₄)₂, pbi = 2-(2-pyridyl)-benzimidazole, was synthesized to mimic copper zinc superoxide dismutase (CuZnSOD). CZpbi was then encapsulated onto a dye (fluorescein isothiocyanate, FITC) functionalized mesoporous silica nanoparticles (MSN) where MSN serves as a nanofactory platform for delivering the catalytic action of the center ...
DOI:: 10.1039/c3tb21052a
: http://dx.doi.org/10.1039/c3tb21052a