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You searched for: Journal name Journal of medicinal food Remove constraint Journal name: Journal of medicinal food Publication year rev 7981-2019 Remove constraint Publication year rev: 7981-2019 Publication Year 2019 Remove constraint Publication Year: 2019 Subject term antineoplastic activity Remove constraint Subject term: antineoplastic activity Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. Assessing Anticancer Potential of Blueberry Flavonoids, Quercetin, Kaempferol, and Gentisic Acid, Through Oxidative Stress and Apoptosis Parameters on HCT-116 Cells

Author:
Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
Source:
Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
ISSN:
1557-7600
Subject:
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
DOI:
10.1089/jmf.2019.0098

2. Gamma-Irradiated Chrysin Improves Anticancer Activity in HT-29 Colon Cancer Cells Through Mitochondria-Related Pathway

Author:
Ha-Yeon Song; Hye-Min Kim; Sajid Mushtaq; Woo Sik Kim; Young Jun Kim; Seung-Taik Lim; Eui-Baek Byun
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 713-721
ISSN:
1557-7600
Subject:
B-lymphocytes; NAD ADP-ribosyltransferase; adenosine; antineoplastic activity; apoptosis; caspase-9; chrysin; colorectal neoplasms; cytotoxicity; gamma radiation; human cell lines; irradiation; membrane potential; mitochondrial membrane; neoplasm cells; reactive oxygen species; signal transduction
Abstract:
... Irradiation technology can improve the biological activities of natural molecules through a structural modification. This study was conducted to investigate the enhancement of the anticancer effects of chrysin upon exposure to gamma irradiation. Gamma irradiation induces the production of new radiolytic peaks simultaneously with the decrease of the chrysin peak, which increases the cytotoxicity in ...
DOI:
10.1089/jmf.2018.4320

3. The Extract of Cordyceps Militaris Inhibited the Proliferation of Cisplatin-Resistant A549 Lung Cancer Cells by Downregulation of H-Ras

Author:
Mi-Kyung Jeong; Hwa-Seung Yoo; In-Cheol Kang
Source:
Journal of medicinal food 2019 v.22 no.8 pp. 823-832
ISSN:
1557-7600
Subject:
Cordyceps militaris; Western blotting; antineoplastic activity; apoptosis; cell cycle checkpoints; lung neoplasms; neoplasm cells; proteomics
Abstract:
... We investigated the antitumor effect of Cordyceps militaris extract (CME) on A549 cisplatin-resistant (CR) lung cancer cells. The proliferation of A549/CR cells was suppressed by CME. Apoptosis of the cells was induced by CME. The cell cycle arrest was observed in the sub-G1 phase in the cells treated with CME. Proteomic profile analysis showed that H-Ras was downregulated in CME-treated cells and ...
DOI:
10.1089/jmf.2018.4232