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You searched for: Journal name Journal of medicinal food Remove constraint Journal name: Journal of medicinal food Publication year rev 7981-2019 Remove constraint Publication year rev: 7981-2019 Source 2019 v.22 no.12 Remove constraint Source: 2019 v.22 no.12
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1. Comparative UHPLC-HRMS Profiling, Toxicological Assessment, and Protection Against H₂O₂-Induced Genotoxicity of Different Parts of Opuntia ficus indica

Author:
Nikolaos Tsafantakis; Efrosini S. Katsanou; Katerina Kyriakopoulou; Eirini-Christina Psarou; Iliana Raptaki; Alexios L. Skaltsounis; Marc Audebert; Kyriaki A. Machera; Nikolas Fokialakis
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1280-1293
ISSN:
1557-7600
Subject:
Ficus benghalensis; Opuntia ficus-indica; antioxidant activity; antioxidants; cladodes; cytotoxicity; dietary supplements; food industry; fruits; functional foods; gallic acid; genotoxicity; glycosides; liquid chromatography; mass spectrometry; medicinal plants; protective effect; quercetin; seed extracts; seeds; toxicity testing
Abstract:
... Opuntia ficus indica has been an important dietary source and a traditionally used medicinal plant. Given the promising health-promoting properties of this plant, a comparative toxicological assessment and antioxidant bioevaluation of extracts from different parts of the plant were carried out in relation to their chemical profile. Toxicity was examined at multiple endpoints using the 3-(4,5-dimet ...
DOI:
10.1089/jmf.2019.0032

2. Identification of Angiotensin I-Converting Enzyme-Inhibitory and Anticoagulant Peptides from Enzymatic Hydrolysates of Chicken Combs and Wattles

Author:
Taliana Kênia Alencar Bezerra; José Thalles Jocelino Gomes de Lacerda; Bruno Ramos Salu; Maria Luiza Vilela Oliva; Maria Aparecida Juliano; Maria Teresa Bertoldo Pacheco; Marta Suely Madruga
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1294-1300
ISSN:
1557-7600
Subject:
amino acids; angiotensin-converting enzyme inhibitors; anticoagulants; chickens; enzymatic hydrolysis; hydrolysates; liquid chromatography; mass spectrometry; molecular weight; peptides; peptidyl-dipeptidase A; protein hydrolysates; slaughter; thromboplastin; wastes; wattles
Abstract:
... Peptides from protein hydrolysate of a mixture of chicken combs and wattles (CCWs) were obtained through enzymatic hydrolysis, and their anticoagulant and inhibitory effects on angiotensin I-converting enzyme (ACE) were investigated. The protein hydrolysate exhibited anticoagulant capacity by the intrinsic pathway (activated partial thromboplastin time) and potent ACE-inhibitory activity. The pept ...
DOI:
10.1089/jmf.2019.0066

3. Lactobacillus plantarum CQPC02-Fermented Soybean Milk Improves Loperamide-Induced Constipation in Mice

Author:
Ruokun Yi; Peng Peng; Jing Zhang; Muying Du; Lingxia Lan; Yu Qian; Jie Zhou; Xin Zhao
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1208-1221
ISSN:
1557-7600
Subject:
Bacteroides; Lactobacillus plantarum; acetylcholinesterase; blood serum; catalase; constipation; defecation; endothelial nitric oxide synthase; feces; gastrins; gastrointestinal transit; glutathione; high performance liquid chromatography; inducible nitric oxide synthase; intestines; isoflavones; malondialdehyde; motilin; myeloperoxidase; neuronal nitric oxide synthase; nitric oxide; somatostatin; soybeans; soymilk; stem cell factor; substance P; superoxide dismutase; transient receptor potential vanilloid channels; vasoactive intestinal peptide; water content
Abstract:
... This study determined the ameliorative effects of the novel microorganism, Lactobacillus plantarum CQPC02 (LP-CQPC02), fermented in soybean milk, on loperamide-induced constipation in Kunming mice. High-performance liquid chromatography revealed that LP-CQPC02-fermented soybean milk (LP-CQPC02-FSM) had six types of soybean isoflavones, whereas Lactobacillus bulgaricus-fermented soybean milk (LB-FS ...
DOI:
10.1089/jmf.2019.4467

4. Oral Administration of Hoodia parviflora Alleviates Insulin Resistance and Nonalcoholic Steatohepatitis

Author:
Meir Mizrahi; Ami Ben Ya'acov; Tomer Adar; Miriam Levy Sklair; Svetlana Gaska; Yaron Ilan
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1189-1198
ISSN:
1557-7600
Subject:
Hoodia parviflora; Psammomys obesus; Western blotting; animal disease models; blood serum; bromine; enzyme-linked immunosorbent assay; fatty liver; food intake; glucose; glucose tolerance tests; hepatitis; histology; inflammation; insulin; insulin resistance; interleukin-6; liver; metabolic syndrome; oral administration; sand; secretion; signal transduction; transactivators; triacylglycerols
Abstract:
... Metabolic syndrome is recognized as a proinflammatory condition leading to hepatic steatosis and nonalcoholic steatohepatitis (NASH). We tested the effects of a succulent species Hoodia parviflora N.E. Br., of the genus Hoodia sweetex Dence, on animal models of NASH and insulin resistance (ob/ob mouse and the sand rat Psammomys obesus). IL6 secretion was evaluated by ELISA and hepatic signal trans ...
DOI:
10.1089/jmf.2019.0093

5. Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy

Author:
Jingfang Luo; Yi Long; Guofeng Ren; Yahui Zhang; Jihua Chen; Ruixue Huang; Lina Yang
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1271-1279
ISSN:
1557-7600
Subject:
alanine transaminase; antioxidant activity; antioxidants; aspartate transaminase; autophagy; blood serum; carbon tetrachloride; cell viability; glutathione peroxidase; hepatoprotective effect; histopathology; lactate dehydrogenase; liver; liver diseases; malondialdehyde; oxidative stress; pathogenesis; polyphenols; pomegranates; proteins; signal transduction; superoxide dismutase
Abstract:
... Hepatic injury is significant in the pathogenesis and development of many types of liver diseases. Punicalagin (PU) is a bioactive antioxidant polyphenol found in pomegranates. To explore its protective effect against carbon tetrachloride (CCl₄)-induced liver injury and the mechanism, Institute of Cancer Research (ICR) mice and L02 cells were used to observe the changes of serum biochemical indica ...
DOI:
10.1089/jmf.2019.4411
PubMed:
31718395
PubMed Central:
PMC6918856

6. The Beneficial Effects of Raffinee in Permanent Occulted Stroke Mice

Author:
Chun-Ching Chiu; Jer-Min Lin; Li-Yi Wu; Tsai-Ching Hsu; Bor-Show Tzang
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1226-1234
ISSN:
1557-7600
Subject:
adjuvants; animal disease models; apoptosis; blood serum; brain; clinical trials; infarction; interleukin-10; interleukin-6; metalloproteinases; mortality; neuroprotective effect; neurotrophins; spinal cord; stroke; therapeutics; tumor necrosis factor-alpha
Abstract:
... Ischemic stroke is a major cause of disability and mortality globally. Although thrombolytic therapy is routinely adopted in cases of ischemic stroke, various alternative natural neuroprotectants are also used as effective adjuvant therapies to recover neurofunction following ischemic stroke. Raffinee, a natural fermented product with strong antioxidant and neuroprotective activities, has antiathe ...
DOI:
10.1089/jmf.2019.4438

7. Effects of Eriobotrya japonica Water Extract on Alcoholic and Nonalcoholic Fatty Liver Impairment

Author:
Jeongeun Mun; Jeongjin Park; Ho-Geun Yoon; Yanghee You; Kyung-Chul Choi; Yoo-Hyun Lee; Kyungmi Kim; Jeongmin Lee; Ok-Kyung Kim; Woojin Jun
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1262-1270
ISSN:
1557-7600
Subject:
Eriobotrya japonica; acetyl-CoA carboxylase; antioxidant activity; beta oxidation; carnitine palmitoyltransferase; ethanol; fatty liver; fatty-acid synthase; free fatty acids; gene expression; hepatocytes; messenger RNA; oleic acid; oxidative stress; peroxisome proliferator-activated receptor alpha; phosphorylation; protective effect; protein kinases; sterols
Abstract:
... The aim of this study was to investigate the potential protective effects of the hot water extract of Eriobotrya japonica (EJW) on EtOH- or free fatty acid (FFA)-induced fatty liver injury in vitro. HepG2/2E1 cells were exposed to EtOH and HepG2 cells were exposed to a mixture of FFAs (oleic acid:palmitic acid, 2:1) to stimulate oxidative stress and to induce lipid accumulation, respectively. Anti ...
DOI:
10.1089/jmf.2019.4493

8. Effects of Green Wheat (Triticum turgidum) and Common Wheat (Triticum aestivum) on the Metabolic Profile of Wistar Rats

Author:
Patrícia Cincotto dos Santos Bueno; Sandra Maria Barbalho; Élen Landgraf Guiguer; Maricelma da Silva Soares de Souza; Isabela Ramos Araújo de Medeiros; Isabella Vasconcelos Zattiti; Manuela dos Santos Bueno; Giovanna Soares Nutels; Ricardo de Alvares Goulart; Adriano Cressoni Araújo
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1222-1225
ISSN:
1557-7600
Subject:
CCR1 receptor; CCR2 receptor; Triticum aestivum; Triticum turgidum; antioxidants; blood glucose; cardiovascular diseases; diabetes; diet; health promotion; high density lipoprotein cholesterol; homeostasis; laboratory animals; low density lipoprotein cholesterol; neoplasms; obesity; phytochemicals; rats; risk factors; triacylglycerols; visceral fat; wheat; whole grain foods
Abstract:
... Studies have shown that the consumption of a diet containing whole grains may improve metabolic homeostasis and is related to the reduction of risk factors for the development of obesity, diabetes, cardiovascular diseases, and cancer. We aimed to investigate the effects of Triticum aestivum and Triticum turgidum on the metabolic profile of Wistar rats. Animals were divided into G1 (control group), ...
DOI:
10.1089/jmf.2019.0089

9. Effects of Lactobacillus plantarum PMO 08 Alone and Combined with Chia Seeds on Metabolic Syndrome and Parameters Related to Gut Health in High-Fat Diet-Induced Obese Mice

Author:
Young Joo Oh; Hee Jung Kim; Tae Seok Kim; Ik Hyun Yeo; Guen Eog Ji
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1199-1207
ISSN:
1557-7600
Subject:
Lactobacillus plantarum; Salvia hispanica; absorption barrier; animal disease models; binding proteins; blood lipids; blood serum; cholesterol 7alpha-monooxygenase; cholesterol metabolism; gene expression; gene expression regulation; high fat diet; intestines; lipid composition; low density lipoprotein cholesterol; males; messenger RNA; metabolic syndrome; mucosa; obesity; occludins; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; risk factors; seeds; synergism; tight junctions
Abstract:
... This study researched the effects of Lactobacillus plantarum PMO 08 alone and combined with chia seeds on metabolic syndrome and parameters related to microbiota modulation and intestinal barrier integrity in obese mice fed high-fat diets (HFDs; 45% kcal fat). Male C57BL/6J mice were acclimated for a period of 2 weeks and then randomly separated into five groups depending on whether they received ...
DOI:
10.1089/jmf.2018.4349

10. Enhancement of Kidney Invigorating Function in Mouse Model by Cistanches Herba Dried Rapidly at a Medium High Temperature

Author:
Yehong Guo; Limin Wang; Qian Li; Cheng Zhao; Ping He; Xudong Ma
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1246-1253
ISSN:
1557-7600
Subject:
Cistanche; Oriental traditional medicine; animal disease models; body weight; cortisol; drying; epididymis; functional foods; intraperitoneal injection; kidneys; ovens; semen quality; sperm quality; temperature; testes; therapeutics; China
Abstract:
... Cistanches Herba is a popular Traditional Chinese Medicine and functional food that is used to treat kidney yang deficiency (KYD) in China. In this study, we investigated the effects of different drying methods for Cistanches Herba on kidney invigoration and yang strengthening. We established a mouse model of KYD by intraperitoneal injection of hydrocortisone for 8 days. We dried slices of Cistanc ...
DOI:
10.1089/jmf.2018.4354

11. Phytochemical/Antioxidant Properties and Individual/Synergistic Actions of Salvia officinalis L. Aqueous Extract and Loperamide on Gastrointestinal Altering Motor Function

Author:
Saber Jedidi; Kais Rtibi; Slimen Selmi; Foued Aloui; Houcine Selmi; Dalanda Wannes; Houcem Sammari; Nourhène Dhawefi; Abbes Chaâbane; Hichem Sebai
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1235-1245
ISSN:
1557-7600
Subject:
C-reactive protein; Salvia officinalis; alkaline phosphatase; anthocyanins; antioxidant activity; castor oil; cholesterol; colorimetry; diarrhea; digestive system diseases; dose response; flavonols; free radical scavengers; hydrogen peroxide; intestines; lipid composition; males; malondialdehyde; median effective concentration; medicinal plants; poisoning; rats; sage; synergism; tannins; transaminases; triacylglycerols
Abstract:
... Medicinal plants are known by pharmacological relevance and were used for long time to prevent/treat numerous gastrointestinal (GI) disorders. The current study focuses on the phytochemical/antioxidant characteristics of sage aqueous extract (SAE), as well as its pharmacological actions on altering motor function in the intestine and related disruptions. In vitro phytochemical/antioxidant properti ...
DOI:
10.1089/jmf.2019.0051

12. The Effects of Supplementing Hancornia speciosa (Mangaba) on Bowel Motility and Inflammatory Profile of Wistar Rats

Author:
Vitória Helena de Oliveira Teixeira Reis; Cynthia Monteiro Santee; Paulo Sérgio Loubet Filho; Thayná Gil Santos; Carolina Amianti; Wander Fernando de Oliveira Filiú; Bruna Paola Murino Rafacho; Luciane Candeloro Portugal; Elisvânia Freitas dos Santos
Source:
Journal of medicinal food 2019 v.22 no.12 pp. 1254-1261
ISSN:
1557-7600
Subject:
Hancornia speciosa; anti-inflammatory activity; blood serum; body weight; cerrado; charcoal; commercialization; constipation; digestive system diseases; drug therapy; food intake; fruits; gastrointestinal motility; genetic factors; health promotion; histopathology; industrialization; laboratory animals; large intestine; lifestyle; liver; magnesium; males; pulp; rats; small intestine; tamarinds; weight gain
Abstract:
... The prevalence of gastrointestinal disorders, such as constipation, has been increasing. Genetic factors and lifestyle are some of the etiologies of this issue, affecting the health of the population. Natural products have properties that contribute to health maintenance and health promotion, including reduction of the inflammatory process. Hancornia speciosa, popularly known as mangaba, is an abu ...
DOI:
10.1089/jmf.2018.0208