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You searched for: Journal Journal of medicinal food Remove constraint Journal: Journal of medicinal food Publication Year 2019 Remove constraint Publication Year: 2019 Source 2019 v.22 no.7 Remove constraint Source: 2019 v.22 no.7
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1. Allicin Inhibits Glutamate Release from Rat Cerebral Cortex Nerve Terminals Through Suppressing Ca²⁺ Influx and Protein Kinase C Activity

Author:
Lu, Cheng-Wei; Hung, Chi-Feng; Lin, Tzu-Yu; Hsieh, Ting Yang; Wang, Su Jane
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 696-702
ISSN:
1557-7600
Subject:
4-aminopyridine; Western blotting; allicin; cAMP-dependent protein kinase; calcium; calcium channels; cerebral cortex; enzyme inhibitors; garlic; glutamic acid; membrane potential; mitogen-activated protein kinase; nerve tissue; neuroprotective effect; phosphorylation; plasma membrane; protein kinase C; rats; synaptosomes
Abstract:
... Evidence indicates that indirect inhibitory regulation of glutamatergic transmission, via reducing glutamate release, may induce neuroprotection. The present work was designed to examine whether allicin, a major component of garlic with neuroprotective effects, affected the release of glutamate evoked by 4-aminopyridine in rat cerebrocortical nerve terminals (synaptosomes). Allicin caused a potent ...
DOI:
10.1089/jmf.2018.4337

2. Antioxidant Activity of Collagen Extracts Obtained from the Skin and Gills of Oreochromis sp.

Author:
Medina-Medrano, José Roberto; Quiñones-Muñoz, Tannia Alexandra; Arce-Ortíz, Abel; Torruco-Uco, Juan Gabriel; Hernández-Martínez, Ricardo; Lizardi-Jiménez, Manuel Alejandro; Varela-Santos, Elizabeth
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 722-728
ISSN:
1557-7600
Subject:
2,2-diphenyl-1-picrylhydrazyl; Oreochromis; active ingredients; antioxidant activity; ascorbic acid; chelating agents; chelation; chemical analysis; collagen; dietary supplements; drugs; evisceration; filleting; flour; free radical scavengers; functional foods; galls; hydrolysis; metal ions; pepsin; raw materials; silage; value-added products; wastes
Abstract:
... Efforts aimed at reduction of fishing waste generated during the evisceration and filleting are scarce. The fishing waste is used in the production of low value-added products, such as flours or silages. It is important to visualize an alternative and profitable use of this waste, as it constitutes a serious environmental problem. This research determined the antioxidant properties of collagenous ...
DOI:
10.1089/jmf.2019.0013

3. Aster glehni Extract Ameliorates Scopolamine-Induced Cognitive Impairment in Mice

Author:
Liao, Yulan; Bae, Ho Jung; Park, Jong Hun; Zhang, Jiabao; Koo, Bokyung; Lim, Mi Kyung; Han, Eun Hye; Lee, Sang Ho; Jung, Seo Yun; Lew, Jae Hwan; Ryu, Jong Hoon
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 685-695
ISSN:
1557-7600
Subject:
Alzheimer disease; Aster glehnii; Western blotting; acetylcholinesterase; adverse effects; cognition; cognitive disorders; cyclic AMP; glycogen synthase kinases; leaves; mechanism of action; memory disorders; mice; mitogen-activated protein kinase; non-specific serine/threonine protein kinase; phosphatidylinositol 3-kinase; phosphorylation; signal transduction; sleep deprivation; tau-protein kinase; therapeutics; Korean Peninsula
Abstract:
... The leaves of Aster glehni Fr. Schm. (Asteraceae) have been used to treat insomnia in Korea. Insomnia is a common adverse effect of therapeutic agents for Alzheimer's disease (AD), and the control of sleep disturbance may prevent dementia. We hypothesized that the leaves of A. glehni can attenuate cognitive dysfunctions observed in AD. We observed the ameliorating effects of the ethanolic extract ...
DOI:
10.1089/jmf.2018.4302

4. Basal and Spasmolytic Effects of a Hydroethanolic Leaf Extract of Melissa officinalis L. on Intestinal Motility: An Ex Vivo Study

Author:
Aubert, Philippe; Guinobert, Isabelle; Blondeau, Claude; Bardot, Valérie; Ripoche, Isabelle; Chalard, Pierre; Neunlist, Michel
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 653-662
ISSN:
1557-7600
Subject:
Melissa officinalis; colon; digestive system diseases; dose response; gastrointestinal motility; ileum; jejunum; leaf extracts; mice; parasympatholytics; patients; phytochemicals; rosmarinic acid
Abstract:
... Melissa officinalis L. (lemon balm) has been used for decades with symptomatic benefits in patients with digestive disorders. However, very little is known on the effects of M. officinalis on the gastrointestinal (GI) tract. In this study, the basal and spasmolytic properties of a hydroethanolic leaf extract (HLE) of M. officinalis were assessed ex vivo on different segments of the GI tract of mic ...
DOI:
10.1089/jmf.2018.0154

5. Cottonseed Oil Protects Against Intestinal Inflammation in Dextran Sodium Sulfate-Induced Inflammatory Bowel Disease

Author:
Park, Jin-Sil; Choi, JeongWon; Hwang, Sun-Hee; Kim, Jae-Kyung; Kim, Eun-Kyung; Lee, Seon-Young; Lee, Bo-In; Park, Sung-Hwan; Cho, Mi-La
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 672-679
ISSN:
1557-7600
Subject:
actin; animal models; coconut oil; colitis; collagen; colon; corn oil; cottonseed oil; dextran; dietary fat; fibrosis; inflammation; interleukin-17; interleukin-6; intestinal microorganisms; metabolism; mice; muscles; neoplasms; olive oil; oxidative stress; protective effect; sodium; sodium sulfate; therapeutics; tumor necrosis factor-alpha; weight loss
Abstract:
... Dietary products may protect against inflammatory bowel disease (IBD) through mechanisms such as forming gut microbiota structures and providing substrates for microbial metabolism. Recently, many studies have been conducted on diets that potentially alleviate or suppress IBD development. To assess the efficacy of dietary oils in treating IBD, we examined the protective effects of olive oil, cocon ...
DOI:
10.1089/jmf.2018.4323

6. Cyanidin 3-Rutinoside, an Anthocyanin Pigment of Schisandra chinensis Baill, Inhibits Allergic Inflammation

Author:
Jeon, Yong-Deok; Aye, Aye; Song, Young-Jae; Kim, Yun-Hoe; Soh, Ju-Ryoun; Jin, Jong-Sik
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 703-712
ISSN:
1557-7600
Subject:
Schisandra chinensis; antioxidants; asthma; atopic dermatitis; bioactive properties; inflammation; interleukin-6; keracyanin; neoplasms; phosphorylation; secretion; therapeutics; transcription factor NF-kappa B; tumor necrosis factor-alpha
Abstract:
... The occurrence of allergy-mediated inflammatory diseases such as asthma and atopic dermatitis have increased, but comprehensive treatment remains difficult. Previous studies have shown that Schisandra chinensis Baill has antioxidant, antidiabetic, and antitumorigenic effects. Cyanidin 3-rutinoside (CR) is the major anthocyanin pigment of S. chinensis. However, the biological effects of CR have bee ...
DOI:
10.1089/jmf.2018.4346

7. Effects of Curcuminoids on Myocardial Injury After Percutaneous Coronary Intervention

Author:
Phrommintikul, Arintaya; Chanchai, Rattanachai; Wongcharoen, Wanwarang
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 680-684
ISSN:
1557-7600
Subject:
C-reactive protein; anti-inflammatory activity; antioxidants; electrocardiography; myocardial infarction; patients; placebos; protein content; surgery; troponin T
Abstract:
... The rise of cardiac troponin post–percutaneous coronary intervention (PCI) is associated with a high risk of long-term cardiovascular events. Previous studies have shown that curcuminoids decreased myocardial injury post–coronary bypass graft surgery through anti-oxidant and anti-inflammatory effects. We sought to examine whether curcuminoids could prevent PCI-related myocardial injury. One-hundre ...
DOI:
10.1089/jmf.2018.4321

8. Gamma-Irradiated Chrysin Improves Anticancer Activity in HT-29 Colon Cancer Cells Through Mitochondria-Related Pathway

Author:
Song, Ha-Yeon; Kim, Hye-Min; Mushtaq, Sajid; Kim, Woo Sik; Kim, Young Jun; Lim, Seung-Taik; Byun, Eui-Baek
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 713-721
ISSN:
1557-7600
Subject:
B-lymphocytes; NAD ADP-ribosyltransferase; adenosine; antineoplastic activity; apoptosis; caspase-9; chrysin; colorectal neoplasms; cytotoxicity; gamma radiation; human cell lines; irradiation; membrane potential; mitochondrial membrane; neoplasm cells; reactive oxygen species; signal transduction
Abstract:
... Irradiation technology can improve the biological activities of natural molecules through a structural modification. This study was conducted to investigate the enhancement of the anticancer effects of chrysin upon exposure to gamma irradiation. Gamma irradiation induces the production of new radiolytic peaks simultaneously with the decrease of the chrysin peak, which increases the cytotoxicity in ...
DOI:
10.1089/jmf.2018.4320

9. Morus alba, a Medicinal Plant for Appetite Suppression and Weight Loss

Author:
Yimam, Mesfin; Jiao, Ping; Hong, Mei; Brownell, Lidia; Lee, Young-Chul; Kim, Hyun-Jin; Nam, Jeong-Bum; Kim, Mi-Ran; Jia, Qi
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 741-751
ISSN:
1557-7600
Subject:
Morus alba; animal disease models; antagonists; appetite; biomarkers; cannabinoids; dose response; drug development; energy intake; food intake; lead; ligands; medicinal plants; metabolic syndrome; mice; obesity; oral administration; rats; visceral fat; weight loss
Abstract:
... The prevalence of obesity is expanding rapidly worldwide, making the disease a global burden with limited treatment options. The current obesity drug development trends suggest the possibility of reducing weight and reverse metabolic disturbances of obesity by controlling appetite. In this study, we screened more than 8000 plants from our plant library for the cannabinoid (CB₁) receptor antagonist ...
DOI:
10.1089/jmf.2017.0142

10. Quercetin Attenuates Visceral Hypersensitivity and 5-Hydroxytryptamine Availability in Postinflammatory Irritable Bowel Syndrome Rats: Role of Enterochromaffin Cells in the Colon

Author:
Qin, Hong-Yan; Zang, Kai-Hong; Zuo, Xiao; Wu, Xin-An; Bian, Zhao-Xiang
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 663-671
ISSN:
1557-7600
Subject:
analgesic effect; cell differentiation; colon; enzymes; genes; hyperplasia; hypersensitivity; irritable bowel syndrome; models; pain; pathogenesis; quercetin; rats; serotonin; tryptophan
Abstract:
... Intestinal enterochromaffin (EC) cell hyperplasia and increased 5-hydroxytryptamine (5-HT) availability play key roles in the pathogenesis of abdominal hypersensitivity of irritable bowel syndrome (IBS). This study aims to study the effect of quercetin on visceral pain and 5-HT availability in postinflammatory IBS (PI-IBS) rats. PI-IBS model rats were administered quercetin by gavage at doses of 5 ...
DOI:
10.1089/jmf.2018.4264

11. The Bioactive Effects of Chicoric Acid As a Functional Food Ingredient

Author:
Peng, Ye; Sun, Quancai; Park, Yeonhwa
Source:
Journal of medicinal food 2019 v.22 no.7 pp. 645-652
ISSN:
1557-7600
Subject:
antioxidants; cell culture; coumaric acids; functional foods; ingredients; neuroprotective effect; obesity
Abstract:
... Chicoric acid, a hydroxycinnamic acid, has been reported to possess a variety of health benefits, including antivirus, antioxidant, anti-inflammation, obesity prevention, and neuroprotection effects. The purpose of this article is to summarize current knowledge of pharmacological and biological effects of chicoric acid. Since most studies to date on chicoric acid have limited their focus to cell c ...
DOI:
10.1089/jmf.2018.0211