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You searched for: Journal name Journal of medicinal food Remove constraint Journal name: Journal of medicinal food Publication year rev 7982-2018 Remove constraint Publication year rev: 7982-2018 Source 2018 v.21 no.1 Remove constraint Source: 2018 v.21 no.1
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1. Apple Cider Vinegar Attenuates Oxidative Stress and Reduces the Risk of Obesity in High-Fat-Fed Male Wistar Rats

Author:
Ben Hmad Halima; Gara Sonia; Khlifi Sarra; Ben Jemaa Houda; Ben Slama Fethi; Aouidet Abdallah
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 70-80
ISSN:
1557-7600
Subject:
animal disease models; antioxidant activity; antioxidant enzymes; apple cider; blood lipids; blood pressure; blood serum; catalase; cider vinegar; enzyme activity; glucose; glutathione peroxidase; high fat diet; hyperlipidemia; hypertension; lipid composition; lipid peroxidation; low density lipoprotein cholesterol; males; malondialdehyde; metabolic syndrome; obesity; oral administration; oxidative stress; risk factors; risk reduction; superoxide dismutase; thiols; trace elements; triacylglycerols; very low density lipoprotein; vitamin E
Abstract:
... Metabolic syndrome is a serious consequence of obesity characterized by increased cardiovascular risk factors such as hypertension, dyslipidemia, and glucose intolerance. While diets enriched with natural antioxidants showed beneficial effects on oxidative stress, blood pressure, and serum lipid composition, diet supplementation with synthetic antioxidants showed contradictive results. Thus, we te ...
DOI:
10.1089/jmf.2017.0039

2. Fermented Extraction of Citrus unshiu Peel Inhibits Viability and Migration of Human Pancreatic Cancers

Author:
Jungwhoi Lee; Jungsul Lee; Myungseung Kim; Jae Hoon Kim
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 5-12
ISSN:
1557-7600
Subject:
Citrus unshiu; adverse effects; antineoplastic activity; antineoplastic agents; byproducts; caspase-3; computer simulation; hesperetin; hesperidin; human diseases; human umbilical vein endothelial cells; juices; models; mortality; naringenin; neoplasm cells; pancreatic neoplasms; prognosis; signal transduction; viability
Abstract:
... Pancreatic cancer is one of the most dangerous cancers with high mortality rates. Despite continuous efforts, there has been limited improvement in its prognosis. In this study, we prepared fermented extract of Citrus unshiu peel (fCUP) from the by-product after juice processing and then examined the anticancer effects of fCUP on human pancreatic cancer cells. Treatment with fCUP inhibited the gro ...
DOI:
10.1089/jmf.2017.3984

3. In Vitro Bioaccessibility and Effect of Mangifera indica (Ataulfo) Leaf Extract on Induced Dyslipidemia

Author:
Eli Mireya Sandoval-Gallegos; Esther Ramírez-Moreno; Juan Gayosso De Lucio; José Arias-Rico; Nelly Cruz-Cansino; Mario I. Ortiz; Raquel Cariño-Cortés
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 47-56
ISSN:
1557-7600
Subject:
2,2-diphenyl-1-picrylhydrazyl; Mangifera indica; adverse effects; animal disease models; antioxidant activity; atherosclerosis; bioavailability; dietary supplements; eating habits; gallic acid; high fat diet; hyperlipidemia; hypertension; lifestyle; lipemic effect; obesity; polyphenols; risk factors; therapeutics; thrombosis
Abstract:
... Cardiovascular diseases (CVDs) are the leading causes of death in the world, and epidemiological evidence points to dietary habits, stress, and obesity as major risk factors promoting pathological conditions like atherosclerosis, hypertension, and thrombosis. Current therapeutic approaches for CVDs rely on lifestyle changes and/or the use of drug agents. However, since the efficacy of such interve ...
DOI:
10.1089/jmf.2017.0042

4. Metabolomic Analysis and Antioxidant Effect of Amla (Emblica officinalis) Extract in Preventing Oxidative Stress-Induced Red Cell Damage and Plasma Protein Alterations: An In Vitro Study

Author:
Rajaa Muthu Packirisamy; Zachariah Bobby; Sankar Panneerselvam; Smitha Mariam Koshy; Sajini Elizabeth Jacob
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 81-89
ISSN:
1557-7600
Subject:
2,2-diphenyl-1-picrylhydrazyl; Phyllanthus emblica; albumins; antioxidant activity; blood proteins; erythrocyte count; erythrocytes; free radicals; gallic acid; glucose; glutathione; in vitro studies; liquid chromatography; mass spectrometry; metabolomics; morphometry; plant extracts; protein content; quercetin; quinic acid; reactive oxygen species
Abstract:
... Amla (Emblica officinalis) has antidiabetic, hypolipidemic, anti-inflammatory, and antioxidant properties, but its effect on free radical induced red cell damage and membrane and plasma protein alterations has not been adequately addressed. The aim of the present study was to evaluate the antioxidant property of amla against oxidative stress-induced red cell damage and plasma protein alterations. ...
DOI:
10.1089/jmf.2017.3942

5. Neuroprotective Effects of Luteolin Against Spinal Cord Ischemia–Reperfusion Injury by Attenuation of Oxidative Stress, Inflammation, and Apoptosis

Author:
Jian Fu; Haibin Sun; Yongzhe Zhang; Wei Xu; Chuan Wang; Yanwei Fang; Jianhui Zhao
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 13-20
ISSN:
1557-7600
Subject:
Western blotting; animal disease models; apoptosis; biotin; cell viability; enzyme activity; enzyme-linked immunosorbent assay; glutathione peroxidase; hindlimbs; inflammasomes; inflammation; interleukin-18; luteolin; malondialdehyde; neurons; neuroprotective effect; oxidative stress; protein synthesis; spinal cord; staining; superoxide dismutase; tissues; tumor necrosis factor-alpha; xanthine oxidase
Abstract:
... Luteolin (LU) is a widely distributed flavonoid with multitarget effects. The objective of this study was to determine whether LU could reduce the ischemia–reperfusion injury of the spinal cord (SCII) in a rat model. Forty-eight rats were divided into four groups: sham, SCII, SCII+L-LU (50 mg/kg), and SCII+H-LU (100 mg/kg). Abdominal aortic occlusion was carried out for 40 min in all groups. Hindl ...
DOI:
10.1089/jmf.2017.4021

6. Sea Cucumber Lipid-Soluble Extra Fraction Prevents Ovalbumin-Induced Allergic Airway Inflammation

Author:
Da-In Lee; Shin Ae Kang; Anisuzzaman Md; U-Cheol Jeong; Feng Jin; Seok-Joong Kang; Jeong-Yeol Lee; Hak Sun Yu
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 21-29
ISSN:
1557-7600
Subject:
Apostichopus japonicus; alcohols; animal disease models; asthma; culture media; eicosapentaenoic acid; fatty acid composition; fractionation; hexane; hyperplasia; inflammation; interleukin-10; interleukin-13; interleukin-17; interleukin-4; interleukin-5; lungs; ovalbumin; spleen; splenocytes; transforming growth factor beta
Abstract:
... In a previous study, our research group demonstrated that sea cucumber (Apostichopus japonicus) extracts ameliorated allergic airway inflammation through CD4⁺CD25⁺Foxp3⁺ T (regulatory T; Treg) cell activation and recruitment to the lung. In this study, we aimed to determine which components of sea cucumber contribute to the amelioration of airway inflammation. We used n-hexane fractionation to sep ...
DOI:
10.1089/jmf.2017.3994

7. Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial

Author:
Gian Carlo Tenore; Domenico Caruso; Giuseppe Buonomo; Maria D'Avino; Rita Santamaria; Carlo Irace; Marialuisa Piccolo; Maria Maisto; Ettore Novellino
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 90-103
ISSN:
1557-7600
Subject:
adults; alopecia; apples; bioactive properties; biosynthesis; cell growth; dietary supplements; drugs; epithelial cells; females; keratin; males; metadata; procyanidins; randomized clinical trials; Italy
Abstract:
... Several pharmaceutical products have been formulated over the past decades for the treatment of male and female alopecia, and pattern baldness, but relatively few metadata on their efficacy have been published. For these reasons, the pharmaceutical and medical attention has recently focused on the discovery of new and safer remedies. Particularly, great interest has been attracted by oligomeric pr ...
DOI:
10.1089/jmf.2017.0016
PubMed:
28956697
PubMed Central:
PMC5775114

8. A Combination with Probiotic Complex, Zinc, and Coenzyme Q10 Attenuates Autoimmune Arthritis by Regulation of Th17/Treg Balance

Author:
Seon-Young Lee; Seung Hoon Lee; JooYeon Jhun; Hyeon-Beom Seo; Kyung Ah Jung; Chul Woo Yang; Sung-Hwan Park; Mi-La Cho
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 39-46
ISSN:
1557-7600
Subject:
blood serum; cartilage; coenzyme Q10; dietary supplements; immunoglobulin G; inflammation; interleukin-17; interleukin-6; probiotics; rheumatoid arthritis; synergism; therapeutics; tumor necrosis factor-alpha; vascular endothelial growth factors; zinc
Abstract:
... Probiotic complex, zinc, and coenzyme Q10 (CoQ10) are recognized dietary supplements with an anti-inflammatory role. Although these supplementations are individually known to benefit rheumatoid arthritis (RA), there is no evidence suggesting any synergic effect. The primary goal of this study is to determine whether probiotic complex, zinc, and CoQ10 attenuate the development of collagen-induced a ...
DOI:
10.1089/jmf.2017.3952

9. The Effects of a Korean Ginseng, GINST15, on Hypo-Pituitary-Adrenal and Oxidative Activity Induced by Intense Work Stress

Author:
Shawn D. Flanagan; William H. DuPont; Lydia K. Caldwell; Vincent H. Hardesty; Emily C. Barnhart; Matthew K. Beeler; Emily M. Post; Jeff S. Volek; William J. Kraemer
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 104-112
ISSN:
1557-7600
Subject:
Panax; antioxidant activity; antioxidants; blood; cortisol; creatine kinase; dose response; ginsenosides; glutathione; humans; inflammation; men; metabolites; muscles; strength training; superoxide dismutase; women
Abstract:
... The effect of GINST15, an enzyme fermented ginseng supplement, on hormonal and inflammatory responses to physical stress in humans is unknown. The purpose of this investigation was to examine the constitutive and stress-induced effects of GINST15 supplement on hypo-pituitary-adrenal (HPA) and antioxidant activity in addition to muscle damage. Ten women (age: 38.7 ± 7.8 years; height: 163.81 ± 4.4  ...
DOI:
10.1089/jmf.2017.0071

10. Morinda citrifolia Leaf Extract Enhances Osteogenic Differentiation Through Activation of Wnt/β-Catenin Signaling

Author:
Hanna Gu; Kanitsak Boonanantanasarn; Moonkyu Kang; Ikhwi Kim; Kyung Mi Woo; Hyun-Mo Ryoo; Jeong-Hwa Baek
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 57-69
ISSN:
1557-7600
Subject:
Morinda citrifolia; alkaline phosphatase; alternative medicine; beta catenin; bone formation; bone fractures; bone morphogenetic proteins; cell differentiation; cytotoxicity; enzyme activity; enzyme inhibitors; herbal medicines; humans; leaves; ligaments; mineralization; osteoblasts; osteocalcin; patients; periodontal diseases; phosphatidylinositol 3-kinase; phosphorylation; rutin; signal transduction; tau-protein kinase; transcription (genetics)
Abstract:
... Morinda citrifolia (Noni) leaf is an herbal medicine with application in the domestic treatment of a broad range of conditions, including bone fracture and luxation. However, the basic mechanism underlying the stimulation of osteogenic differentiation by Noni leaf extract remains poorly understood. This study aimed to examine the effect of this extract on osteogenic differentiation and the mechani ...
DOI:
10.1089/jmf.2017.3933

11. Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine Bark, Pycnogenol

Author:
Peter Jörg Rohdewald
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 1-4
ISSN:
1557-7600
Subject:
Pinus pinaster; anti-inflammatory activity; blood cells; blood serum; catechin; clinical trials; hospitals; ingestion; intestinal microorganisms; intestines; metabolites; nonsteroidal anti-inflammatory agents; osteoarthritis; pain; patients; phenolic acids; plant extracts; procyanidins; proteinases; synovial fluid; taxifolin
Abstract:
... This review summarizes the effects of the standardized proprietary bark extract of the French maritime pine (Pycnogenol®) in mild osteoarthritis (OA), stage 1 and 2. The extract exerts antioxidative, anti-inflammatory, and chondroprotective effects in vitro and in vivo. Its phenolic acids as well as catechin and taxifolin are quickly absorbed. Active metabolites, produced by gut microbiota in the ...
DOI:
10.1089/jmf.2017.0015
PubMed:
28836883
PubMed Central:
PMC5775113

12. Standardized Kaempferia parviflora Extract Enhances Exercise Performance Through Activation of Mitochondrial Biogenesis

Author:
Mi-Bo Kim; Taeyoon Kim; Changhee Kim; Jae-Kwan Hwang
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 30-38
ISSN:
1557-7600
Subject:
Kaempferia parviflora; animal disease models; athletic performance; biogenesis; exercise; gene expression regulation; high fat diet; mitochondria; myotubes; obesity; peroxisome proliferator-activated receptor gamma; plant extracts; protein kinases; protein synthesis; regulator genes; signal transduction; skeletal muscle
Abstract:
... Exercise enhances mitochondrial biogenesis in skeletal muscle. Increased mitochondrial function and content can contribute to the improvement in skeletal muscle function and the benefits of exercise by increasing the response to energy demands. The effect of standardized Kaempferia parviflora extract (KPE) on exercise performance was accessed in L6 myotubes and C57BL/6J mice. KPE significantly act ...
DOI:
10.1089/jmf.2017.3989