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You searched for: Journal name Journal of medicinal food Remove constraint Journal name: Journal of medicinal food Publication year rev 7983-2017 Remove constraint Publication year rev: 7983-2017 Source 2017 v.20 no.12 Remove constraint Source: 2017 v.20 no.12
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1. Alzheimer's Disease—Current Status and Future Directions

Author:
Bhardwaj Deepshikha; Mitra Connie; Narasimhulu Chandrakala Aluganti; Riad Aladdin; Doomra Mitsushita; Parthasarathy Sampath
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1141-1151
ISSN:
1557-7600
Subject:
Alzheimer disease; alleles; antioxidants; apolipoprotein E; brain; diagnostic techniques; etiology; memory disorders; neurodegenerative diseases; neurons; nutrition; oxidative stress; pathophysiology; patients; risk factors; sensation; synapse
Abstract:
... Alzheimer's disease (AD) is an age-related neurodegenerative disorder of the brain. The presence of amyloid-beta (Aβ) plaques, neurofibrillary tangles (NFTs), loss of neurons, synapses, and altered sensory perceptions, including memory loss, delineate AD. However, the cause of AD is not clearly known. Several genetic and nongenetic factors have been implicated in the disease. Of the genes, the ɛ4 ...
DOI:
10.1089/jmf.2017.0093

2. Curcumin Alleviates the Functional Gastrointestinal Disorders of Mice In Vivo

Author:
Yu Jing; Xu Wen-hua; Sun Wei; Sun Yi; Guo Zhi-li; Yu Xiao-ling
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1176-1183
ISSN:
1557-7600
Subject:
acetylcholine; arginine; atropine; bioactive properties; curcumin; digestive system diseases; gastric emptying; in vitro studies; in vivo studies; intragastric administration; jejunum; mice; nitric oxide; peristalsis; polyphenols; rhizomes; turmeric
Abstract:
... Curcumin is a natural polyphenol extracted from the turmeric rhizome, which has a wide range of biological activities, but until now the effects of curcumin on the gastrointestinal peristalsis have not been fully understood. In vivo study, we observed the effects of curcumin on gastric emptying and intestinal propulsion rates of mice in normal state and in delayed state by atropine (ATR) or nitric ...
DOI:
10.1089/jmf.2017.3964

3. Extracts of Porphyra tenera (Nori Seaweed) Activate the Immune Response in Mouse RAW264.7 Macrophages via NF-κB Signaling

Author:
Song Ji-Hye; Kang Hee-Bum; Park Seung-Ho; Jeong Ji-Hoon; Park Jeongjin; You Yanghee; Lee Yoo-Hyun; Lee Jeongmin; Kim Eungpil; Choi Kyung-Chul; Jun Woojin
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1152-1159
ISSN:
1557-7600
Subject:
IKappaB kinase; Porphyra; cell viability; cytotoxicity; edible seaweed; ethanol; immune response; interferon-gamma; interleukin-10; interleukin-6; macroalgae; macrophages; mice; phosphorylation; signal transduction; transcription factor NF-kappa B; tumor necrosis factor-alpha; Asia
Abstract:
... Porphyra tenera, also known as nori, is a red algal species of seaweed. It is cultivated in Asia for culinary purposes. We report that P. tenera extract (PTE) enhances the immune response in mouse macrophages. We found that P. tenera extract regulates the NF-κB IκB kinase (IKK) signaling pathway, and we assessed the expression and translocation of p65, a subunit of NF-κB, in RAW264.7 mouse macroph ...
DOI:
10.1089/jmf.2017.4014

4. Long-Term Dietary Supplementation with Yerba Mate Ameliorates Diet-Induced Obesity and Metabolic Disorders in Mice by Regulating Energy Expenditure and Lipid Metabolism

Author:
Choi Myung-Sook; Park Hyo Jin; Kim Sang Ryong; Kim Do Yeon; Jung Un Ju
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1168-1175
ISSN:
1557-7600
Subject:
adipocytes; adiposity; animal disease models; blood lipids; cholesterol; dietary supplements; droplets; energy expenditure; epididymis; excretion; experimental diets; fatty liver; fatty-acid synthase; free fatty acids; gastric inhibitory polypeptide; gene expression; genes; glucose tolerance; high fat diet; homeostasis; hyperlipidemia; insulin; insulin resistance; leptin; lipid content; lipid metabolism; liver; messenger RNA; mice; obesity; phosphatidate phosphatase; resistin; triacylglycerols; white adipose tissue; yerba mate
Abstract:
... This study evaluated whether long-term supplementation with dietary yerba mate has beneficial effects on adiposity and its related metabolic dysfunctions in diet-induced obese mice. C57BL/6J mice were randomly divided into two groups and fed their respective experimental diets for 16 weeks as follows: (1) control group fed with high-fat diet (HFD) and (2) mate group fed with HFD plus yerba mate. D ...
DOI:
10.1089/jmf.2017.3995

5. The Anti-Inflammatory and Antioxidant Effects of Salvia officinalis on Lipopolysaccharide-Induced Inflammation in Rats

Author:
Kolac Umut Kerem; Ustuner Mehmet Cengiz; Tekin Neslihan; Ustuner Derya; Colak Emine; Entok Emre
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1193-1200
ISSN:
1557-7600
Subject:
Salvia officinalis; albino; antioxidant activity; antioxidants; blood serum; catalase; enzyme activity; erythrocytes; females; flavonoids; glutathione peroxidase; inflammation; kidneys; lipopolysaccharides; liver; lungs; malondialdehyde; models; nitric oxide; oxidative stress; pathophysiology; rats; superoxide dismutase; tissues; tomography; transcription factor NF-kappa B; tumor necrosis factor-alpha
Abstract:
... Salvia officinalis, which has a high phenolic acid and flavonoid content, is a powerful antioxidant and anti-inflammatory herb. Inflammation plays an important role in the pathophysiology of many diseases and could cause damage by means of oxidative stress. The aim of this study was to investigate the anti-inflammatory and antioxidant activity of S. officinalis formed lipopolysaccharide (LPS)-indu ...
DOI:
10.1089/jmf.2017.0035

6. The Edible Mushroom Pleurotus djamor Produces Metabolites with Lethal Activity Against the Parasitic Nematode Haemonchus contortus

Author:
Pineda-Alegría Jesús Antonio; Sánchez-Vázquez José Ernesto; González-Cortazar Manases; Zamilpa Alejandro; López-Arellano María Eugenia; Cuevas-Padilla Edgar Josúe; Mendoza-de-Gives Pedro; Aguilar-Marcelino Liliana
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1184-1192
ISSN:
1557-7600
Subject:
Haemonchus contortus; Pleurotus djamor; anthelmintics; beta-sitosterol; eggs; gas chromatography-mass spectrometry; hatching; larvae; maceration; medicinal properties; metabolites; mortality; mushrooms; stearic acid
Abstract:
... Pleurotus djamor is an edible mushroom that has medicinal properties. This study aimed to assess the in vitro activity of P. djamor extracts and fractions against Haemonchus contortus eggs and exsheathed infective larvae (L₃). Crude hydroalcoholic extracts were obtained by maceration and fractions were obtained through chromatography. Metabolite identity was determined using gas chromatography/mas ...
DOI:
10.1089/jmf.2017.0031

7. Low-Molecular-Weight Oligonol, a Polyphenol Derived from Lychee Fruit, Attenuates Experimental Reflux Esophagitis and HCl/Ethanol-Induced Gastric Ulcer

Author:
Roh Seong-Soo; Shin Mi-Rae; Shin Sung Ho; Lee Joo Young; Song Yeong Ok; Woo Minji; Jeong Kap-Seop; Noh Jeong Sook
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1214-1221
ISSN:
1557-7600
Subject:
2,2-diphenyl-1-picrylhydrazyl; anti-inflammatory activity; antioxidant activity; ascorbic acid; catalase; esophageal diseases; ethanol; free radicals; hydrochloric acid; in vitro studies; in vivo studies; inducible nitric oxide synthase; interleukin-1beta; litchis; mice; models; oligomerization; oxidative stress; polymers; polyphenols; protective effect; rats; reactive oxygen species; stomach ulcers; superoxide dismutase; tumor necrosis factor-alpha
Abstract:
... Oligonol, a polyphenol derived from lychee fruit, is produced by an oligomerization process that converts high-molecular-weight polyphenol polymers into low-molecular-weight oligomers. Evidence suggests that oligonol exerts its beneficial effects based on antioxidant and anti-inflammatory properties. This study was the first to investigate the antioxidative and anti-inflammatory effects of oligono ...
DOI:
10.1089/jmf.2017.3972

8. Overview of Signaling Mechanism Pathways Employed by BPAid in Vasodilatory Activity

Author:
Loh Yean Chun; Tan Chu Shan; Ch'ng Yung Sing; Ahmad Mariam; Ng Chiew Hoong; Yam Mun Fei
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1201-1213
ISSN:
1557-7600
Subject:
Alisma; Fourier transform infrared spectroscopy; Gastrodia elata; Oriental traditional medicine; Panax notoginseng; Pueraria montana var. thomsonii; Uncaria rhynchophylla; action potentials; calcium channels; cyclic GMP; etiology; guanylate cyclase; herbs; hypertension; inositols; nitric oxide; physicochemical properties; potassium; prostacyclin; saponins; vasodilation
Abstract:
... Hypertension, one of the famous “silent killers” that can attack people at any age, is a current hot topic among scientists due to multiple syndromic behavior and concomitant diseases. The new scientific-based Traditional Chinese Medicine (TCM) formulation approach was used in a previous study by combining five TCM herbs, including Gastrodia elata Bl., Uncaria rhynchophylla (Miq.) Miq. ex Havil., ...
DOI:
10.1089/jmf.2017.3958

9. The Effect of Anthocyanin-Rich Purple Vegetable Diets on Metabolic Syndrome in Obese Zucker Rats

Author:
Ayoub Hala M.; McDonald Mary Ruth; Sullivan James Alan; Tsao Rong; Platt Mathew; Simpson Jeremy; Meckling Kelly A.
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1240-1249
ISSN:
1557-7600
Subject:
anthocyanins; bioactive compounds; bioactive properties; carrots; color; cultivars; diastolic blood pressure; fruits; functional foods; glucose; glucose tolerance; glucose tolerance tests; high fat diet; homeostasis; hypertension; insulin resistance; insulin tolerance test; metabolic syndrome; models; obesity; potatoes; rats
Abstract:
... Consumption of highly colored fruits and vegetables rich in anthocyanins has been associated with numerous health benefits. Purple carrots (PC) and purple potatoes (PP) have higher anthocyanin concentrations and higher biological activities compared with less pigmented cultivars. We hypothesized that substitution of the majority of carbohydrate in a high fat diet with PP or PC, for 8 weeks, would ...
DOI:
10.1089/jmf.2017.0025

10. Chlorogenic Acid-Enriched Extract of Ilex kudingcha C.J. Tseng Inhibits Angiogenesis in Zebrafish

Author:
Zhong Tao; Piao Linghua; Kim Hyun Jung; Liu Xiande; Jiang Shengnan; Liu Guomin
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1160-1167
ISSN:
1557-7600
Subject:
Danio rerio; Ilex kaushue; angiogenesis; antineoplastic activity; antineoplastic agents; apoptosis; blood; chlorogenic acid; dose response; endothelial cells; eyes; fever; high performance liquid chromatography; ingredients; magnetism; nuclear magnetic resonance spectroscopy; pruritus; tea; toxins; China
Abstract:
... Kudingcha is a particularly bitter tasting tea that has been widely used in China to eliminate fever and itching eyes, and to clear blood toxins. Kudingcha is considered of value for its potential anticancer effects that are attributed to the presence of characteristic bioactive ingredients. The chlorogenic acid (CGA) derivatives 3-0-caffeoylquinic acid, 5-0-caffeoylquinic acid, 3,5-0-dicaffeoylqu ...
DOI:
10.1089/jmf.2017.3987

11. Dolichos lablab Protects Against Nonalcoholic Fatty Liver Disease in Mice Fed High-Fat Diets

Author:
Im A-Rang; Kim Yun Hee; Kim Young Hwa; Yang Won-Kyung; Kim Seung Hyung; Song Kwang Hoon
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1222-1232
ISSN:
1557-7600
Subject:
Lablab purpureus subsp. purpureus; adiponectin; animal models; blood serum; body fat; body weight; cholesterol; diarrhea; droplets; fatty acids; fatty liver; forage; genes; hepatoprotective effect; high fat diet; histopathology; liver function; low fat diet; males; medicine; mice; milk; triacylglycerols; China; India
Abstract:
... Hyacinth bean, Dolichos lablab or Lablab purpureus, has been used for centuries in India and China as an edible pod and animal forage, as well as to treat diarrhea and other gastrointestinal disease in traditional Korean medicine. Recently, we have demonstrated that D. lablab extract (DLL-Ex) prevented free fatty acid-induced lipid accumulation in an in vitro cellular nonalcoholic fatty liver dise ...
DOI:
10.1089/jmf.2017.4036

12. The Effect of Experimental Supplementation with the Klamath Algae Extract Klamin on Attention-Deficit/Hyperactivity Disorder

Author:
Cremonte Maurizio; Sisti Davide; Maraucci Ilaria; Giribone Simona; Colombo Evelin; Rocchi Marco Bruno Luigi; Scoglio Stefano
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1233-1239
ISSN:
1557-7600
Subject:
abnormal behavior; childhood; data collection; dopamine; lakes; microalgae; nervous system diseases; therapeutics
Abstract:
... Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological condition with onset in childhood. The disorder is characterized by inattention, impulsivity, and/or motor hyperactivity, which often affect the development and social integration of affected subjects. Phenylethylamine (PEA), naturally contained in the Klamath Lake microalgae and concentrated in the Klamin® extract, is an ...
DOI:
10.1089/jmf.2016.0181