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Journal name
Journal of medicinal food
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Publication Year
2019
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Subject term
polyphenols
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- Author:
- Yousef A. Al-Dashti; Roberta R. Holt; John G. Carson; Carl L. Keen; Robert M. Hackman
- Source:
- Journal of medicinal food 2019 v.22 no.10 pp. 982-992
- ISSN:
- 1557-7600
- Subject:
- animal models; blood serum; bone health; bone resorption; cardiovascular diseases; cross-over studies; experimental design; lipid metabolism; osteoporosis; oxidants; postmenopause; prunes; women
- Abstract:
- ... Osteoporosis and cardiovascular disease are global health burdens, with postmenopausal women being at great risk. Dried plums/prunes (DPs) have been reported to provide bone health benefits in animal models, which is consistent with in vitro models. Data from human studies suggest that DP intake can enhance lipid metabolism, anti-inflammatory, and oxidant defense systems, which can impact cardiova ...
- DOI:
- 10.1089/jmf.2018.0209
- https://doi.org/10.1089/jmf.2018.0209
- Author:
- Yon-Suk Kim; Eun-Kyung Kim; Xin Dong; Jin-Su Park; Woen-Bin Shin; Su-Jin Kim; Eun-Ae Go; Pyo-Jam Park; Beong-Ou Lim
- Source:
- Journal of medicinal food 2019 v.22 no.5 pp. 508-520
- ISSN:
- 1557-7600
- Subject:
- Danio rerio; Lindera glauca; antioxidant activity; catalase; cell viability; enzyme activity; flavonoids; gene expression; glutathione peroxidase; glutathione transferase; lipid peroxidation; models; oxidative stress; polyphenols; protective effect; reactive oxygen species; sulfonic acids; superoxide dismutase; therapeutics; thiobarbituric acid; thiocyanates
- Abstract:
- ... In this study, we investigated the antioxidant and protective effect of Lindera glauca stem (LGS) extracts against oxidative stress. We compared antioxidant properties of water extract (LGSW) with ethanol extract (LGSE) by determining the contents responsible for antioxidant activities such as polyphenols and flavonoids. Antioxidant properties were also determined by 2,2′-azinobis-(3-ethylbenzothi ...
- DOI:
- 10.1089/jmf.2018.4289
- https://doi.org/10.1089/jmf.2018.4289
- Author:
- Nara Rúbia Rodrigues do Nascimento-Silva; Maria Margareth Veloso Naves
- Source:
- Journal of medicinal food 2019 pp. -
- ISSN:
- 1557-7600
- Subject:
- Caryocar brasiliense; Caryocar villosum; almonds; animal models; anticarcinogenic activity; antioxidants; ash content; byproducts; calcium; carotenoids; cerrado; dietary fiber; ellagic acid; energy; exocarp; fruit pulp; functional foods; gallic acid; in vivo studies; magnesium; mesocarp; oleic acid; palmitic acid; polyphenols; quercetin; seed oils; zinc
- Abstract:
- ... Pequi (Caryocar) pulp, the most consumed component of pequi fruit, is one of the richest Brazilian carotenoid sources, and the most important carotenoid food source native to the Cerrado. However, there are considerable differences among pequi species regarding total carotenoids content and carotenoids profile. Caryocar brasiliense Camb. pulp presents higher content of total carotenoids than Caryo ...
- DOI:
- 10.1089/jmf.2018.0149
- https://doi.org/10.1089/jmf.2018.0149
- Author:
- Jingfang Luo; Yi Long; Guofeng Ren; Yahui Zhang; Jihua Chen; Ruixue Huang; Lina Yang
- Source:
- Journal of medicinal food 2019 v.22 no.12 pp. 1271-1279
- ISSN:
- 1557-7600
- Subject:
- alanine transaminase; antioxidant activity; antioxidants; aspartate transaminase; autophagy; blood serum; carbon tetrachloride; cell viability; glutathione peroxidase; hepatoprotective effect; histopathology; lactate dehydrogenase; liver; liver diseases; malondialdehyde; oxidative stress; pathogenesis; polyphenols; pomegranates; proteins; signal transduction; superoxide dismutase
- Abstract:
- ... Hepatic injury is significant in the pathogenesis and development of many types of liver diseases. Punicalagin (PU) is a bioactive antioxidant polyphenol found in pomegranates. To explore its protective effect against carbon tetrachloride (CCl₄)-induced liver injury and the mechanism, Institute of Cancer Research (ICR) mice and L02 cells were used to observe the changes of serum biochemical indica ...
- DOI:
- 10.1089/jmf.2019.4411
- PubMed:
- 31718395
- PubMed Central:
- PMC6918856
- https://doi.org/10.1089/jmf.2019.4411
- Author:
- Hae-Rim Kim; Bo-Mi Kim; Ji-Yeon Won; Kyung-Ann Lee; Hyun Myung Ko; Young Sun Kang; Sang-Heon Lee; Kyoung-Woon Kim
- Source:
- Journal of medicinal food 2019 v.22 no.2 pp. 152-161
- ISSN:
- 1557-7600
- Subject:
- CD4-positive T-lymphocytes; acid phosphatase; coculture; enzyme activity; enzyme-linked immunosorbent assay; flow cytometry; gene expression; interleukin-17; ligands; macrophage colony-stimulating factor; mammals; messenger RNA; mitogen-activated protein kinase; monocytes; osteoclasts; polyphenols; protein content; quantitative polymerase chain reaction; quercetin; rapamycin; rheumatoid arthritis; secretion; therapeutics; transcription factor NF-kappa B
- Abstract:
- ... We investigated the immune-regulatory function of quercetin, in interleukin (IL)-17-produced osteoclastogenesis in rheumatoid arthritis (RA). RA fibroblasts-like synoviocytes (RA-FLS) were stimulated with IL-17, and the mRNA expression and secretion of receptor activator of nuclear factor kappa-B ligand (RANKL) were detected by real-time polymerase chain reaction and enzyme-linked immunosorbent as ...
- DOI:
- 10.1089/jmf.2018.4259
- https://doi.org/10.1089/jmf.2018.4259
- Author:
- Jefferson Romáryo Duarte da Luz; Thayse Evellyn Silva do Nascimento; Leandro Vinicius Fernandes de Morais; Ana Katarina Menezes da Cruz; Adriana Augusto de Rezende; José Brandão Neto; Marcela Abbott Galvão Ururahy; André Ducati Luchessi; Jorge A. López; Hugo Alexandre Oliveira Rocha; Maria das Graças Almeida
- Source:
- Journal of medicinal food 2019 v.22 no.4 pp. 384-392
- ISSN:
- 1557-7600
- Subject:
- Turnera subulata; active ingredients; adverse effects; anticoagulant activity; anticoagulants; blood coagulation; coagulation; ethyl acetate; etiology; flavones; glycosides; heparin; leaves; mechanism of action; phytotherapy; polyphenols; prothrombin; thrombin; thromboplastin; thrombosis; toxicity
- Abstract:
- ... Cardiovascular and thromboembolic disturbances are the main causes of disease-related deaths worldwide. Regardless of the etiological factors involved in thrombus formation, coagulation is mainly activated by thrombin, one of the most important blood clotting molecules. Thus, this study evaluated the Turnera subulata leaf crude extract, its ethyl acetate fraction effect on the coagulation cascade, ...
- DOI:
- 10.1089/jmf.2018.0141
- https://doi.org/10.1089/jmf.2018.0141
- Author:
- Matthew L. Tripp; Clinton J. Dahlberg; Sarah Eliason; Joseph J. Lamb; Joseph J. Ou; Wei Gao; Jay Bhandari; David Graham; Enkhmart Dudleenamjil; John G. Babish
- Source:
- Journal of medicinal food 2019 v.22 no.5 pp. 479-489
- ISSN:
- 1557-7600
- Subject:
- C-reactive protein; Mediterranean diet; adverse effects; biomarkers; body fat; body mass index; cardiovascular diseases; comorbidity; constipation; diastolic blood pressure; dietary supplements; flatulence; high density lipoprotein; inflammation; lifestyle; longevity; low density lipoprotein cholesterol; nitric oxide; nitrites; nitrogen dioxide; noninsulin-dependent diabetes mellitus; observational studies; overweight; oxidation; risk factors; triacylglycerols; waist circumference
- Abstract:
- ... Among the comorbidities of high body mass index, cardiovascular disease continued to be the leading cause of death and disability globally in 2015, while type 2 diabetes remained second. The primary objectives of this observational study were to confirm the safety, tolerability, and efficacy of our calorie-restricted Mediterranean diet with targeted dietary supplementation (PROG1) using globally r ...
- DOI:
- 10.1089/jmf.2018.0063
- https://doi.org/10.1089/jmf.2018.0063
- Author:
- Sanique South; Jacquelynn Lucero; Parakat Vijayagopal; Shanil Juma
- Source:
- Journal of medicinal food 2019 v.22 no.10 pp. 1032-1040
- ISSN:
- 1557-7600
- Subject:
- adults; anti-inflammatory activity; bioactive compounds; blueberries; cartilage; cell proliferation; dose response; etiology; fruits; gene expression regulation; in vivo studies; inflammation; interleukin-1; polyphenols; rabbits; reverse transcriptase polymerase chain reaction; rheumatoid arthritis; stromelysin 1; therapeutics; transcription factor NF-kappa B; tumor necrosis factor-alpha; vegetables
- Abstract:
- ... Rheumatoid arthritis (RA) is an autoimmune and chronic inflammatory disease resulting in joint destruction and disability in the adult population. The etiology of RA is not well understood and presently there is no known cure for this disease. The accumulation and proliferation of fibroblast-like synoviocytes may be involved in cartilage destruction. Both in vitro and in vivo studies support an an ...
- DOI:
- 10.1089/jmf.2019.0046
- https://doi.org/10.1089/jmf.2019.0046
- Author:
- Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
- Source:
- Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
- ISSN:
- 1557-7600
- Subject:
- 2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
- Abstract:
- ... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
- DOI:
- 10.1089/jmf.2019.0098
- https://doi.org/10.1089/jmf.2019.0098
- Author:
- Catalina Carrasco-Pozo; María Jose Cires; Martin Gotteland
- Source:
- Journal of medicinal food 2019 v.22 no.8 pp. 753-770
- ISSN:
- 1557-7600
- Subject:
- Western diets; adipocytes; adipose tissue; adverse effects; animal models; bariatric surgery; bioactive compounds; body weight changes; cardiovascular diseases; clinical trials; drug therapy; drugs; energy expenditure; enzymes; epigallocatechin gallate; flavanols; food intake; genetic polymorphism; green tea; lipogenesis; lipolysis; medicinal plants; mortality; obesity; plant extracts; polyphenols; quercetin; weight loss
- Abstract:
- ... Obesity is a worldwide epidemic, which is characterized by the excess accumulation of adipose tissue and to an extent that impairs both the physical and psychosocial health and well-being. There are several weight-loss strategies available, including dietary modification, pharmacotherapy, and bariatric surgery, but many are ineffective or not a long-term solution. Bioactive compounds present in me ...
- DOI:
- 10.1089/jmf.2018.0193
- https://doi.org/10.1089/jmf.2018.0193