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- Author:
- Sezer, Ebru Demirel; Oktay, Latife Merve; Karadadaş, Elif; Memmedov, Hikmet; Selvi Gunel, Nur; Sözmen, Eser
- Source:
- Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
- ISSN:
- 1557-7600
- Subject:
- 2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
- Abstract:
- ... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
- DOI:
- 10.1089/jmf.2019.0098
-
https://dx.doi.org/10.1089/jmf.2019.0098
- Author:
- Kaenkumchorn, Tanyaporn; Kesavan, Anil
- Source:
- Journal of medicinal food 2019 v.22 no.11 pp. 1092-1099
- ISSN:
- 1557-7600
- Subject:
- Crohn disease; adverse effects; carbohydrates; colitis; curcumin; databases; dietary supplements; enteral feeding; environmental factors; inflammation; intestines; malnutrition; omega-3 fatty acids; pathogenesis; prospective studies
- Abstract:
- ... Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a life-long relapsing and remitting condition characterized by inflammation of the intestine. While the exact pathogenesis of IBD is unclear, the current belief is that both genetic and environmental factors play a role in development of disease. Management options include nutritional, pharmacological, and ...
- DOI:
- 10.1089/jmf.2019.0063
-
https://dx.doi.org/10.1089/jmf.2019.0063
- Author:
- Cadiz, Mikaela P.; Schara, Mackenzie R.; Kemp, Bailey H.; Gibbons Johnson, Rachel M.
- Source:
- Journal of medicinal food 2019 v.22 no.11 pp. 1146-1150
- ISSN:
- 1557-7600
- Subject:
- Echinacea purpurea; concanavalin A; dose response; immune system; immunomodulators; interferon-gamma; interleukin-2; mice; splenocytes; traditional medicine; tumor necrosis factors
- Abstract:
- ... Echinacea purpurea is a common herbal remedy used to treat a variety of illnesses, though its health benefits and effects on the immune system have not been fully elucidated. In this study, we investigated the effect of E. purpurea root extract on the survival of concanavalin A (ConA)-activated murine splenocytes and the production of the cytokines interferon-gamma (IFN-γ), interleukin-2 (IL-2), a ...
- DOI:
- 10.1089/jmf.2019.0065
-
https://dx.doi.org/10.1089/jmf.2019.0065
- Author:
- Jesuz, Vanessa Azevedo de; Elias Campos, Monique de Barros; Rosse de Souza, Vanessa; Bede, Teresa Palmiciano; Moraes, Bianca Portugal Tavares de; Silva, Adriana Ribeiro; de Albuquerque, Cassiano Felippe Gonçalves; Blondet de Azeredo, Vilma; Teodoro, Anderson Junger
- Source:
- Journal of medicinal food 2019 v.22 no.11 pp. 1175-1182
- ISSN:
- 1557-7600
- Subject:
- biomarkers; blood glucose; blood serum; cardiovascular diseases; enzymes; fatty liver; flow cytometry; heart; hepatocytes; high density lipoprotein cholesterol; high fat diet; interleukin-1beta; interphase; liver; lycopene; metabolism; mitosis; neoplasms; rats; tomato sauce; tumor necrosis factor-alpha
- Abstract:
- ... This study evaluated the effects of tomato sauce and lycopene on hepatic and cardiac cell biomarkers in rats fed a high-fat diet. Animals were split into five groups: control group, high-fat group (HG), high-fat tomato sauce group, high-fat lycopene 2 mg, and high-fat lycopene 4 mg. Food and water were offered ad libitum, whereas tomato sauce and lycopene (2 and 4 mg/day) were offered daily for 60 ...
- DOI:
- 10.1089/jmf.2019.0014
-
https://dx.doi.org/10.1089/jmf.2019.0014
- Author:
- Kim, Ye Jin; Ryu, Ri; Choi, Ji-Young; Choi, Myung-Sook
- Source:
- Journal of medicinal food 2019 v.22 no.11 pp. 1100-1109
- ISSN:
- 1557-7600
- Subject:
- Platycodon grandiflorus; adipocytes; animal disease models; beta oxidation; blood; carnitine palmitoyltransferase; diabetes; energy requirements; enzyme activity; epididymis; ethanol; excretion; fatty acid composition; fatty acids; fatty liver; free fatty acids; heat production; high fat diet; hyperlipidemia; lipolysis; obesity; transcriptome; white adipose tissue
- Abstract:
- ... Adipocytes regulate lipid metabolism according to physiological energy requirements. A dysfunctional lipid metabolism can lead to obesity and its complications such as hepatic steatosis, diabetes, and hyperlipidemia. In our study, the impact of Platycodon grandiflorus root ethanol extract (PGH) on lipid excretion and thermogenesis-related markers in diet-induced obesity mice was analyzed. Our data ...
- DOI:
- 10.1089/jmf.2019.4443
-
https://dx.doi.org/10.1089/jmf.2019.4443
- Author:
- Kim, Mi-Bo; Kim, Changhee; Hwang, Jae-Kwan
- Source:
- Journal of medicinal food 2019 v.22 no.11 pp. 1159-1167
- ISSN:
- 1557-7600
- Subject:
- AMP-activated protein kinase; Sigesbeckia; adenosine triphosphate; anti-allergic agents; biogenesis; exercise; high fat diet; immunosuppression; mitochondria; myotubes; peroxisome proliferator-activated receptor gamma; regulator genes; signal transduction; skeletal muscle
- Abstract:
- ... Siegesbeckia orientalis has been reported to exhibit anti-allergic, anti-infertility, anti-inflammatory, anti-rheumatic, and immunosuppressive activities. However, there are very few studies describing its stimulatory effects on exercise capacity. This study elucidated whether S. orientalis extract (SOE) standardized to kirenol content can enhance exercise endurance by increasing mitochondrial bio ...
- DOI:
- 10.1089/jmf.2019.4485
-
http://dx.doi.org/10.1089/jmf.2019.4485