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You searched for: Journal name Journal of medicinal food Remove constraint Journal name: Journal of medicinal food Subject term antineoplastic agents Remove constraint Subject term: antineoplastic agents Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. Assessing Anticancer Potential of Blueberry Flavonoids, Quercetin, Kaempferol, and Gentisic Acid, Through Oxidative Stress and Apoptosis Parameters on HCT-116 Cells

Author:
Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
Source:
Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
ISSN:
1557-7600
Subject:
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
DOI:
10.1089/jmf.2019.0098

2. Antiproliferative Activity of Extracts of Campomanesia adamantium (Cambess.) O. Berg and Isolated Compound Dimethylchalcone Against B16-F10 Murine Melanoma

Author:
Magalli C.B. Lima e Silva; Danielle Bogo; Caroline A.F. Alexandrino; Renata T. Perdomo; Patrícia de O. Figueiredo; Pamela R. do Prado; Fernanda R. Garcez; Monica C.T. Kadri; Thalita V.N. Ximenes; Rita de Cassia A. Guimarães; Ulana C. Sarmento; Maria Lígia R. Macedo
Source:
Journal of medicinal food 2018 v.21 no.10 pp. 1024-1034
ISSN:
1557-7600
Subject:
Campomanesia; antineoplastic activity; antineoplastic agents; apoptosis; bioactive compounds; caspase-3; cerrado; coculture; diodes; fruit pulp; fruits; high performance liquid chromatography; indigenous species; ionization; macrophages; melanoma; methylene chloride; mice; nitric oxide; phenolic compounds; spectrometers
Abstract:
... Campomanesia adamantium, a native species of the Brazilian Cerrado, is characterized as a natural source of phenolic compounds and has known potential anticancer activities. This study aimed to evaluate the chemical profile of dichloromethane extracts of pulp (DEGPU) and peel (DEGPE) from the fruits of C. adamantium and to identify compounds with antiproliferative effects in vitro against melanoma ...
DOI:
10.1089/jmf.2018.0001

3. Fermented Extraction of Citrus unshiu Peel Inhibits Viability and Migration of Human Pancreatic Cancers

Author:
Jungwhoi Lee; Jungsul Lee; Myungseung Kim; Jae Hoon Kim
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 5-12
ISSN:
1557-7600
Subject:
Citrus unshiu; adverse effects; antineoplastic activity; antineoplastic agents; byproducts; caspase-3; computer simulation; hesperetin; hesperidin; human diseases; human umbilical vein endothelial cells; juices; models; mortality; naringenin; neoplasm cells; pancreatic neoplasms; prognosis; signal transduction; viability
Abstract:
... Pancreatic cancer is one of the most dangerous cancers with high mortality rates. Despite continuous efforts, there has been limited improvement in its prognosis. In this study, we prepared fermented extract of Citrus unshiu peel (fCUP) from the by-product after juice processing and then examined the anticancer effects of fCUP on human pancreatic cancer cells. Treatment with fCUP inhibited the gro ...
DOI:
10.1089/jmf.2017.3984

4. Chlorogenic Acid-Enriched Extract of Ilex kudingcha C.J. Tseng Inhibits Angiogenesis in Zebrafish

Author:
Zhong Tao; Piao Linghua; Kim Hyun Jung; Liu Xiande; Jiang Shengnan; Liu Guomin
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1160-1167
ISSN:
1557-7600
Subject:
Danio rerio; Ilex kaushue; angiogenesis; antineoplastic activity; antineoplastic agents; apoptosis; blood; chlorogenic acid; dose response; endothelial cells; eyes; fever; high performance liquid chromatography; ingredients; magnetism; nuclear magnetic resonance spectroscopy; pruritus; tea; toxins; China
Abstract:
... Kudingcha is a particularly bitter tasting tea that has been widely used in China to eliminate fever and itching eyes, and to clear blood toxins. Kudingcha is considered of value for its potential anticancer effects that are attributed to the presence of characteristic bioactive ingredients. The chlorogenic acid (CGA) derivatives 3-0-caffeoylquinic acid, 5-0-caffeoylquinic acid, 3,5-0-dicaffeoylqu ...
DOI:
10.1089/jmf.2017.3987

5. Crude Garlic Extract Inhibits Cell Proliferation and Induces Cell Cycle Arrest and Apoptosis of Cancer Cells In Vitro

Author:
Bagul Mukta; Kakumanu Srikanth; Wilson Thomas A.
Source:
Journal of medicinal food 2015 v.18 no.7 pp. 731-737
ISSN:
1557-7600
Subject:
antineoplastic agents; apoptosis; caspases; cell cycle checkpoints; cell proliferation; coculture; colon; colorectal neoplasms; fetal bovine serum; garlic; human cell lines; humans; lipids; macrophages; mice; neoplasm cells
Abstract:
... Garlic and its lipid-based extracts have played an important medicinal role in humans for centuries that includes antimicrobial, hypoglycemic, and lipid-lowering properties. The present study was to investigate the effects of crude garlic extract (CGE) on the proliferation of human breast, prostate, hepatic, and colon cancer cell lines and mouse macrophageal cells, not previously studied. The huma ...
DOI:
10.1089/jmf.2014.0064

6. Production of Bioactive Compounds with Antitumor Activity Against Sarcoma 180 by Pleurotus sajor-caju

Author:
Assis Ivaneliza Simionato; Chaves Mariane Bonatti; Silveira Marcia Luciane Lange; Gern Regina Maria Miranda; Wisbeck Elisabeth; Júnior Agenor Furigo; Furlan Sandra Aparecida
Source:
Journal of medicinal food 2013 v.16 no.11 pp. 1004-1012
ISSN:
1557-7600
Subject:
Pleurotus sajor-caju; ammonium sulfate; antineoplastic activity; antineoplastic agents; biomass; bioreactors; calcium carbonate; containers; culture media; exopolysaccharides; glucose; growth retardation; mice; mycelium; pH; peptones; sarcoma; yeast extract
Abstract:
... This work studied the influence of culture medium composition and pH on exopolysaccharide (EPS) production by Pleurotus sajor-caju and validates the antitumor activity of the produced EPSs and of the mycelial biomass (intracellular polysaccharides [IPSs]) against Sarcoma 180 (S180) cells. The effect of the initial concentrations of (NH₄)₂SO₄, yeast extract and soy peptone on EPS production by P. s ...
DOI:
10.1089/jmf.2012.0267

7. Anti-Invasive Activity of Anthocyanins Isolated from Vitis coignetiae in Human Hepatocarcinoma Cells

Author:
Shin, Dong Yeok; Lee, Won Sup; Kim, Seok Hyun; Kim, Min Jeong; Yun, Jeong Won; Lu, Jing Nan; Lee, Sung Joong; Tsoy, Irina; Kim, Hye Jung; Ryu, Chung Ho; Kim, Gi Young; Kang, Ho Sung; Shin, Sung Chul; Choi, Yung Hyun
Source:
Journal of medicinal food 2009 v.12 no.5 pp. 967-972
ISSN:
1096-620X
Subject:
anthocyanins; human diseases; human cell lines; dose response; quantitative analysis; hepatoma; cell growth; metalloproteinases; medicinal plants; Vitis; plant extracts; bioassays; antineoplastic agents; tumor necrosis factor-alpha; growth retardation; chemical constituents of plants; enzyme activity; gene expression regulation; South Korea
DOI:
10.1089/jmf.2008.1338
PubMed:
19857058

8. The Grape Component Piceatannol Induces Apoptosis in DU145 Human Prostate Cancer Cells via the Activation of Extrinsic and Intrinsic Pathways

Author:
Kim, Eun Ji; Park, Heesook; Park, So Young; Jun, Jong-Gab; Park, Jung Han Yoon
Source:
Journal of medicinal food 2009 v.12 no.5 pp. 943-951
ISSN:
1096-620X
Subject:
grapes; stilbenes; disease prevention; plant extracts; dose response; antineoplastic agents; mitochondria; prostatic neoplasms; Vitis vinifera; medicinal properties; apoptosis; human diseases; quantitative analysis; seeds; enzyme inhibitors; enzyme activity; membrane permeability; biochemical pathways; cytochrome c; chemical constituents of plants; protein content
DOI:
10.1089/jmf.2008.1341
PubMed:
19857055

9. Treatment with Astragali Radix and Angelicae Radix Enhances Erythropoietin Gene Expression in the Cyclophosphamide-Induced Anemic Rat

Author:
Chang, Mun Seog; Kim, Do Rim; Ko, Eun Bit; Choi, Bong Jae; Park, Soo Yeon; Kang, Soon Ah; Park, Seong Kyu
Source:
Journal of medicinal food 2009 v.12 no.3 pp. 637-642
ISSN:
1096-620X
Subject:
anemia; rats; Astragalus; drug therapy; dose response; disease prevention; cytotoxicity; medicinal plants; Angelica; plant extracts; bioassays; animal models; cyclophosphamide; chemical constituents of plants; medicinal properties; gene expression regulation; roots; erythropoietin
DOI:
10.1089/jmf.2007.0727
PubMed:
19627214

10. Cytokine-Mimetic Properties of Some Philippine Food and Medicinal Plants

Author:
Tulin, E.E.; Ecleo, Z.T.
Source:
Journal of medicinal food 2007 v.10 no.2 pp. 290-299
ISSN:
1096-620X
Subject:
interspecific variation; bone marrow cells; medicinal plants; cytokines; plant extracts; antineoplastic agents; splenocytes; pH; traditional foods; indigenous species; chemical constituents of plants; temperature; molecular weight; cell proliferation; chemical structure; chemical degradation; anticarcinogenic activity; Philippines
DOI:
10.1089/jmf.2006.067
PubMed:
17651065

11. Cytotoxic effect of buckwheat (Fagopyrum esculentum Moench) hull against cancer cells

Author:
Kim, S.H.; Cui, C.B.; Kang, I.J.; Kim, S.Y.; Ham, S.S.
Source:
Journal of medicinal food 2007 v.10 no.2 pp. 232-238
ISSN:
1096-620X
Subject:
sarcoma; fractionation; cytotoxicity; anticarcinogenic activity; plant extracts; dosage; mice; Fagopyrum esculentum; animal models; antineoplastic agents; in vitro studies; cell lines; hulls; buckwheat
DOI:
10.1089/jmf.2006.1089
PubMed:
17651057

12. Selaginella tamariscina induces apoptosis via a caspase-3-mediated mechanism in human promyelocytic leukemia cells

Author:
Ahn, S.H.; Mun, Y.J.; Lee, S.W.; Kwak, S.; Choi, M.K.; Baik, S.K.; Kim, Y.M.; Woo, W.H.
Source:
Journal of medicinal food 2006 v.9 no.2 pp. 138-144
ISSN:
1096-620X
Subject:
enzyme activation; dose response; DNA fragmentation; leukemia; humans; biomarkers; cytotoxicity; anticarcinogenic activity; reactive oxygen species; oxidative stress; medicinal plants; caspase-3; gene expression; antineoplastic agents; cultured cells; Selaginella; apoptosis; drug crops; herbal medicines
DOI:
10.1089/jmf.2006.9.138
PubMed:
16822197

13. Immunomodulating activity of arabinogalactan and fucoidan in vitro

Author:
Choi, E.M.; Kim, A.J.; Kim, Y.O.; Hwang, J.K.
Source:
Journal of medicinal food 2005 v.8 no.4 pp. 446-453
ISSN:
1096-620X
Subject:
immunomodulators; cell lines; phagocytosis; nitrites; macrophage activation; biomarkers; hydrogen peroxide; lymphocytes; cell-mediated immunity; antineoplastic agents; arabinogalactans; interleukins; cytotoxicity; fucoidan; tumor necrosis factor-alpha; mice; in vitro studies; enzyme activity; animal models; anticarcinogenic activity
DOI:
10.1089/jmf.2005.8.446
PubMed:
16379554

14. Effect of Alstonia scholaris in enhancing the anticancer activity of berberine in the Ehrlich ascites carcinoma-bearing mice

Author:
Jagetia, G.C.; Baliga, M.S.
Source:
Journal of medicinal food 2004 v.7 no.2 pp. 235-244
ISSN:
1096-620X
Subject:
mice; animal models; Alstonia scholaris; berberine; anticarcinogenic activity; antineoplastic agents; carcinoma; plant extracts; bark; ethanol; water; dose response; ascites; combination drug therapy; drug toxicity; carcinogenesis
DOI:
10.1089/1096620041224094
PubMed:
15298773

15. Effect of maitake (Grifola frondosa) D-Fraction on the activation of NK cells in cancer patients

Author:
Kodama, Noriko; Komuta, Kiyoshi; Nanba, Hiroaki
Source:
Journal of medicinal food 2003 v.6 no.4 pp. 371-377
ISSN:
1096-620X
Subject:
drug therapy; blood serum; liver; T-lymphocytes; disease surveillance; macrophage activation; immunotherapy; Grifola frondosa; interleukin-2; disease severity; enzyme-linked immunosorbent assay; antineoplastic agents; metastasis; mice; patients; mushrooms; natural killer cells; breast neoplasms
Abstract:
... Maitake D-Fraction, extracted from maitake mushroom, has been reported to exert its antitumor effect in tumor-bearing mice by enhancing the immune system through activation of macrophages, T cells, and natural killer (NK) cells. In a previous study, the combination of immunotherapy with the maitake D-Fraction and chemotherapy suggested that the D-Fraction may have the potential to decrease the siz ...
DOI:
10.1089/109662003772519949
PubMed:
14977447

16. Chemoprevention with food phytochemicals: screening, rodent studies, and action mechanisms

Author:
Murakami, A.; Koshimizu, K.; Ohigashi, H.
Source:
Journal of medicinal food 1998 v.1 no.1 pp. 29-38
ISSN:
1096-620X
Subject:
foods; chemical composition; chemoprevention; disease prevention; neoplasms; bioassays; medicinal properties; animal models; metabolites; anions; oxides; screening; mechanism of action; antineoplastic agents; carcinogenesis; plant extracts; food composition; leukocytes; inactivation; oxidation; chemical constituents of plants
DOI:
10.1089/jmf.1998.1.29

17. Garlic: medicinal food or nutritious medicine?

Author:
Nagourney, R.A.
Source:
Journal of medicinal food 1998 v.1 no.1 pp. 13-28
ISSN:
1096-620X
Subject:
antimicrobial properties; history; thrombosis; juices; antihypertensive agents; neoplasms; antilipemic agents; garlic; Allium sativum; antineoplastic agents; myocardial depressants; chemical constituents of plants; health foods
DOI:
10.1089/jmf.1998.1.13

18. Oral limonene: combined prenylation inhibitor therapy of cancer

Author:
Nagourney, R.A.
Source:
Journal of medicinal food 1998 v.1 no.2 pp. 83-88
ISSN:
1096-620X
Subject:
limonene; medicinal properties; neoplasms; ubiquinones; drug therapy; antineoplastic agents; patients; adverse effects; toxicity
DOI:
10.1089/jmf.1998.1.83