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- Staley, Christopher; Sadowsky, Michael J.
- Journal of microbiological methods 2018 v.154 pp. 14-18
- DNA; algorithms; biogeography; bioinformatics; ecosystems; genetic markers; habitats; high-throughput nucleotide sequencing; interdisciplinary research; metagenomics; microbial communities; microbiome; microorganisms; research programs; statistical analysis; technology
- ... Recent advancements in metagenomic-based studies, especially analyses of amplicon-based DNA sequencing targeting taxonomic marker genes, has led to an unprecedented characterization of microbial communities from diverse ecosystems around the world. While originally constrained by a lack of appropriate analytical tools and sequencing depth, new technologies and computational and statistical algorit ...