Author: "Ellis, Lee D." / Journal: Journal of natural products / Publication Year: 2019 / Subject: 4 selected

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Author:: Ellis, Lee D., et al. ; Rajotte, Isabelle; Rafuse, Cheryl; Wright, Elliott J.; Achenbach, John C.; McCarron, Pearse; Show all 6 Authors
Source:: Journal of natural products 2019 v.82 no.7 pp. 1945-1952
ISSN:: 1520-6025
Subject:: Danio rerio; Gonyaulax; biomass; hydroxylation; liquid chromatography; mass spectrometry; nuclear magnetic resonance spectroscopy; solvents; toxicity; yessotoxin
Abstract:: ... Liquid chromatography–high-resolution mass spectrometry (LC-HRMS) analysis of a Namibian strain of Gonyaulax spinifera showed the presence of a number of yessotoxins (YTXs). Principal among these were YTX (1), homoYTX (2), and a tentative hydroxylated analogue that did not correspond to any previously confirmed YTX structures. Culturing the G. spinifera strain afforded sufficient biomass for purif ...
DOI:: 10.1021/acs.jnatprod.9b00318
: http://dx.doi.org/10.1021/acs.jnatprod.9b00318