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- Author:
- Xie, Linglin; Wu, Dayong; Bundy, Amy; Claycombe, Kate
- Source:
- Journal of nutrition 2017 v.12 no.1
- ISSN:
- 0022-3166
- Subject:
- adipocytes; adipose tissue; adiposity; analysis of variance; animal models; energy; gene expression; high fat diet; inflammation; insulin resistance; interleukin-1beta; interleukin-6; macrophages; malnutrition; neonates; obesity; phenotype; progeny; protein intake; proteins; rats
- Abstract:
- ... Adipose tissue macrophages (ATM) are implicated in adipose tissue inflammation and obesity-related insulin resistance. Maternal low protein models result in fetal programming of obesity. The study aims to answer whether maternal undernutrition by protein restriction affects the ATM M1 or M2 phenotype under postnatal high fat diet in F1 offspring. Using a rat model of prenatal low protein (LP, 8% p ...
- Handle:
- 10113/5661745
- DOI:
- 10.1371/journal.pone.0169581
- PubMed:
- 28141871
- PubMed Central:
- PMC5283658
- CHORUS:
- 10.1371/journal.pone.0169581
-
http://dx.doi.org/10.1371/journal.pone.0169581
- Author:
- Hileman, Corrilynn O.; Dirajlal-Fargo, Sahera; Lam, Suet Kam; Kumar, Jessica; Lacher, Craig; Combs Jr., Gerald F.
- Source:
- Journal of nutrition 2015 v.145 no.10 pp. 2293-2299
- ISSN:
- 0022-3166
- Subject:
- CD8-positive T-lymphocytes; HIV infections; Human immunodeficiency virus 1; RNA; adults; antioxidants; antiretroviral agents; atherosclerosis; blood plasma; body mass index; immune response; inflammation; linear models; nutrient deficiencies; placebos; proteinase inhibitors; regression analysis; selenium; selenoproteins; therapeutics
- Abstract:
- ... Background: Selenium is an essential constituent of selenoproteins, which play a substantial role in antioxidant defense and inflammatory cascades. Selenium deficiency is associated with disease states characterized by inflammation, including cardiovascular disease (CVD). Although HIV infection has been associated with low selenium, the role ofselenium status in HIV-related CVD is unclear. Objecti ...
- Handle:
- 10113/61453
- DOI:
- 10.3945/jn.115.214577
- PubMed:
- 26269240
- PubMed Central:
- PMC4580958
- CHORUS:
- 10.3945/jn.115.214577
-
http://dx.doi.org/10.3945/jn.115.214577
- Author:
- Gaffney-Stomberg, Erin; Cao, Jay J.; Lin, Gregory G.; Wulff, Charles R.; Murphy, Nancy E.; Young, Andrew J.; McClung, James P.; Pasiakos, Stefan M.
- Source:
- Journal of nutrition 2014 v.144 no.6 pp. 821-829
- Subject:
- animal models; biomarkers; bone density; bone resorption; calcium; calcium channels; dairy protein; dietary restriction; duodenum; energy; femur; high protein diet; low calorie diet; protein intake; protein sources; rats; soy protein
- Abstract:
- ... High protein diets may attenuate bone loss during energy restriction (ER). The objective of the current study was to determine whether high protein diets suppress bone turnover and improve bone quality in rats during ER and whether dietary protein source affects this relationship. Eighty 12-week old male Sprague Dawley rats were randomized to receive one of 4 study diets: 10% milk protein (CP-MP), ...
- DOI:
- 1 0.3945/Jn .113.188532.
-
http://dx.doi.org/1 0.3945/Jn .113.188532.
- Author:
- Claycombe, Kate J.; Uthus, Eric O.; Roemmich, James N.; Johnson, LuAnn K.; Johnson, W. Thomas
- Source:
- Journal of nutrition 2013 v.143 pp. 1533
- ISSN:
- 1541-6100
- Subject:
- adipocytes; adipose tissue; conception; dietary protein; energy; fat intake; genes; high fat diet; insulin resistance; insulin-like growth factor II; lactation; low protein diet; maternal nutrition; messenger RNA; mitochondrial DNA; obesity; pregnancy; prenatal development; progeny; protein intake; rats; weaning
- Abstract:
- ... Maternal low protein diets during prenatal development contribute to the development of obesity and insulin resistance in offspring. In this study, obese-prone Sprague -Dawley rats were fed diets having either 8% (low protein, LP) or 20% (normal protein, NP) protein for 3-wk prior to conception and throughout pregnancy and lactation. At weaning, their offspring were fed diets for 12 wk having norm ...
- Handle:
- 10113/58304
- DOI:
- 10 3945/in 113.178038
-
http://dx.doi.org/10 3945/in 113.178038
- Author:
- Chiuve, Stephanie E.; Fung, Teresa T.; Rimm, Eric B.; Hu, Frank B.; McCullough, Marjorie L.; Wang, Molin; Stampfer, Meir J.; Willett, Walter C.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1009-1018
- ISSN:
- 0022-3166
- Subject:
- Dietary Guidelines; breast feeding; chronic diseases; death; diabetes; foods; healthy diet; men; myocardial ischemia; nutrients; prediction; professionals; risk; stroke; women
- Abstract:
- ... The Healthy Eating Index-2005 (HEI-2005) measures adherence to the 2005 Dietary Guidelines for Americans, but the association between the HEI-2005 and risk of chronic disease is not known. The Alternative Healthy Eating Index (AHEI), which is based on foods and nutrients predictive of chronic disease risk, was associated inversely with chronic disease risk previously. We updated the AHEI, includin ...
- DOI:
- 10.3945/jn.111.157222
- PubMed:
- 22513989
- PubMed Central:
- PMC3738221
-
http://dx.doi.org/10.3945/jn.111.157222
- Author:
- Black, Lucinda J.; Seamans, Kelly M.; Cashman, Kevin D.; Kiely, Mairead
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1102-1108
- ISSN:
- 0022-3166
- Subject:
- adults; food fortification; fortified foods; meta-analysis; models; population distribution; public health; systematic review; vitamin D; vitamin deficiencies
- Abstract:
- ... Food fortification is a potentially effective public health strategy to increase vitamin D intakes and circulating 25-hydroxyvitamin D [25(OH)D] concentrations. We updated a previous systematic review to evaluate current evidence from randomized controlled intervention studies in community-dwelling adults of the effect of fortified foods on 25(OH)D concentrations. Ovid MEDLINE, PubMed, CINAHL, Emb ...
- DOI:
- 10.3945/jn.112.158014
- PubMed:
- 22513988
-
http://dx.doi.org/10.3945/jn.112.158014
- Author:
- Bork, Kirsten; Cames, Cécile; Barigou, Sabah; Cournil, Amandine; Diallo, Aldiouma
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1116-1122
- ISSN:
- 0022-3166
- Subject:
- foods; appetite; infancy; toddlers; preschool children; child nutrition; infants; Africa; Latin America
- Abstract:
- ... Several studies have shown an association between an infant and young child feeding index (ICFI) and height-for-age Z-score (HAZ) in Latin America and Africa. A previous study was unable to reproduce these findings in 500 rural Senegalese 12–42-mo-old children. The relationship of ICFI, dietary diversity index (DDI), food variety index (FVI), meal frequency index (MFI), and breastfeeding (BF) to H ...
- DOI:
- 10.3945/jn.112.157602
- PubMed:
- 22535757
-
http://dx.doi.org/10.3945/jn.112.157602
- Author:
- Shea, M. Kyla; Booth, Sarah L.; Nettleton, Jennifer A.; Burke, Gregory L.; Chen, Haiying; Kritchevsky, Stephen B.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1060-1066
- ISSN:
- 0022-3166
- Subject:
- African Americans; Hispanic Americans; Whites; adults; atherosclerosis; body mass index; cholesterol; chronic diseases; clinical trials; detection limit; ethnic differences; phylloquinone; races; United States
- Abstract:
- ... Differences in micronutrient status are reported to contribute to racial and ethnic differences in chronic diseases. Diseases related to vitamin K are reported to differ by race and ethnicity, but it is unclear if circulating vitamin K concentrations similarly differ. We examined racial and ethnic differences in serum phylloquionone (K1) in the Multiethnic Study of Atherosclerosis (MESA) (mean ± S ...
- DOI:
- 10.3945/jn.111.154278
- PubMed:
- 22496402
- PubMed Central:
- PMC3349976
-
http://dx.doi.org/10.3945/jn.111.154278
- Author:
- Frith, Amy L.; Naved, Ruchira T.; Persson, Lars Ake; Rasmussen, Kathleen M.; Frongillo, Edward A.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1095-1101
- ISSN:
- 0022-3166
- Subject:
- breast feeding; child development; dietary supplements; food and nutrition programs; food groups; food security; governmental programs and projects; infants; linear models; mothers; nutritional intervention; pregnancy; questionnaires; satellites; women; Bangladesh
- Abstract:
- ... Food insecurity is detrimental to child development, yet little is known about the combined influence of food insecurity and nutritional interventions on child development in low-income countries. We proposed that women assigned to an early invitation time to start a prenatal food supplementation program could reduce the negative influence of food insecurity on maternal-infant interaction. A cohor ...
- DOI:
- 10.3945/jn.111.155358
- PubMed:
- 22496401
- PubMed Central:
- PMC3349981
-
http://dx.doi.org/10.3945/jn.111.155358
- Author:
- Qin, Bo; Xun, Pengcheng; He, Ka
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1067-1073
- ISSN:
- 0022-3166
- Subject:
- case-control studies; cohort studies; fish; fish consumption; meta-analysis; pancreatic neoplasms; polyunsaturated fatty acids; risk; systematic review
- Abstract:
- ... Long-chain (n-3) PUFA (LC-PUFA) have been hypothesized to be beneficial in preventing pancreatic carcinogenesis, but the associations of fish or LC-PUFA intake with pancreatic cancer found in epidemiologic studies have been controversial and inconclusive. To estimate the overall association of LC-PUFA or fish intake with pancreatic cancer, we performed a systematic literature search of English-lan ...
- DOI:
- 10.3945/jn.111.156711
- PubMed:
- 22535760
- PubMed Central:
- PMC3349977
-
http://dx.doi.org/10.3945/jn.111.156711
- Author:
- Derom, Marie-Laure; Martínez-González, Miguel AÁ.; Sayón-Orea, Maria del Carmen; Bes-Rastrollo, Maira; Beunza, Juan J.; Sánchez-Villegas, Almudena
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1053-1059
- ISSN:
- 0022-3166
- Subject:
- antagonists; behavior disorders; calcium; cations; cohort studies; dose response; drugs; enzymatic reactions; magnesium; mental depression; neurons; nutrient density; physicians; regression analysis; risk; universities
- Abstract:
- ... Magnesium is the second most predominant intracellular cation and it is an important cofactor in over 300 enzymatic reactions. It is a calcium antagonist and a voltage-dependant blocker of the N-methyl-D-aspartate channel, which plays a role in the entrance of calcium into the neuron. Other mechanisms also add biological plausibility to neuro-protective properties for magnesium, including an inver ...
- DOI:
- 10.3945/jn.111.155572
- PubMed:
- 22513990
-
http://dx.doi.org/10.3945/jn.111.155572
- Author:
- Gernand, Alison D.; Christian, Parul; Schulze, Kerry J.; Shaikh, Saijuddin; Labrique, Alain B.; Shamim, Abu Ahmed; West, Keith P., Jr
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1109-1115
- ISSN:
- 0022-3166
- Subject:
- bioelectrical impedance; body mass index; body water; fetal development; hematocrit; hemoglobin; nutritional status; pregnancy; pregnant women; regression analysis; risk; weight gain; Bangladesh
- Abstract:
- ... Plasma volume expansion has been associated with fetal growth. Our objective was to examine the associations between maternal nutritional status in early pregnancy and extracellular water (ECW), total body water (TBW), and percentage plasma volume change across pregnancy. In a subsample of 377 pregnant women participating in a cluster-randomized trial of micronutrient supplementation, hemoglobin, ...
- DOI:
- 10.3945/jn.111.155978
- PubMed:
- 22535759
- PubMed Central:
- PMC3349982
-
http://dx.doi.org/10.3945/jn.111.155978
- Author:
- Daniel, Carrie R.; Sinha, Rashmi; Park, Yikyung; Graubard, Barry I.; Hollenbeck, Albert R.; Morton, Lindsay M.; Cross, Amanda J.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1074-1080
- ISSN:
- 0022-3166
- Subject:
- animal fats and oils; animal models; diet study techniques; fish; heme iron; heterocyclic amines; lifestyle; lymphocytic leukemia; meat; meat consumption; meat processing; men; nitrates; nitrites; non-Hodgkin lymphoma; poultry; proteins; questionnaires; regression analysis; risk; temperature; women; United States
- Abstract:
- ... Meat intake has been inconsistently associated with risk of non-Hodgkin lymphoma (NHL), a heterogeneous group of malignancies of the lymphoid tissue etiologically linked to immunomodulatory factors. In a large U.S. cohort, we prospectively investigated several biologically plausible mechanisms related to meat intake, including meat-cooking and meat-processing compounds, in relation to NHL risk by ...
- DOI:
- 10.3945/jn.112.158113
- PubMed:
- 22535761
- PubMed Central:
- PMC3349978
-
http://dx.doi.org/10.3945/jn.112.158113
- Author:
- Fernstrom, John D.; Munger, Steven D.; Sclafani, Anthony; de Araujo, Ivan E.; Roberts, Ashley; Molinary, Samuel
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1134S-1141S
- ISSN:
- 0022-3166
- Subject:
- brain; gastrointestinal system; mouth; rodents; sweeteners; sweetness; taste
- Abstract:
- ... A remarkable amount of information has emerged in the past decade regarding sweet taste physiology. This article reviews these data, with a particular focus on the elucidation of the sweet taste receptor, its location and actions in taste transduction in the mouth, its nontaste functions in the gastrointestinal tract (e.g., in enteroendocrine cells), and the brain circuitry involved in the sensory ...
- DOI:
- 10.3945/jn.111.149567
- PubMed:
- 22573784
- PubMed Central:
- PMC3738222
-
http://dx.doi.org/10.3945/jn.111.149567
- Author:
- Lin, Gang; Liu, Chuang; Feng, Cuiping; Fan, Zhiyong; Dai, Zhaolai; Lai, Changhua; Li, Zhen; Wu, Guoyao; Wang, Junjun
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 990-998
- ISSN:
- 0022-3166
- Subject:
- adverse effects; amino acids; ammonia; animal and human health; animal production; body weight; energy metabolism; fetal development; fetus; foods; gestational age; gilts; glucose; growth retardation; hormones; humans; lipids; metabolites; neonatal mortality; postnatal development; pregnancy; progeny; umbilical veins; urea
- Abstract:
- ... Intrauterine growth restriction (IUGR) remains a major problem for both human health and animal production due to its association with high rates of neonatal morbidity and mortality, low efficiency of food utilization, permanent adverse effects on postnatal growth and development, and long-term health and productivity of the offspring. However, the underlying mechanisms for IUGR are largely unknow ...
- DOI:
- 10.3945/jn.111.153411
- PubMed:
- 22513987
-
http://dx.doi.org/10.3945/jn.111.153411
- Author:
- Tetrick, Mark A.; Crenshaw, Thomas D.; Benevenga, Norlin J.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 999-1003
- ISSN:
- 0022-3166
- Subject:
- carbon; glucose; medium chain fatty acids; metabolism; muscles; oxidation; piglets; tricarboxylic acid cycle
- Abstract:
- ... An in vitro muscle strip incubation system was developed to measure the rate of catabolism of 1 mmol/L [1-14C]octanoate, 1 mmol/L [1-14C]nonanoate, 1 mmol/L [9-14C]nonanoate, and 10 mmol/L [U-14C]glucose by measuring the recovery of 14CO2. Muscle strips (13 mm x 1.5 mm, approximately 50 mg) were isolated from triceps brachii and gracilis muscles of newborn and 2-d-old, small (<950 g) and large (>1 ...
- DOI:
- 10.3945/jn.111.150797
- PubMed:
- 22513984
-
http://dx.doi.org/10.3945/jn.111.150797
- Author:
- Brauner, Reinhard; Johannes, Christian; Ploessl, Florian; Bracher, Franz; Lorenz, Reinhard L.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 981-989
- ISSN:
- 0022-3166
- Subject:
- ABC transporters; absorption; agonists; atherosclerosis; campesterol; cholesterol; cholesterol metabolism; enterocytes; ethanol; excretion; food marketing; gene expression; high density lipoprotein; liver; models; receptors; secretion
- Abstract:
- ... Phytosterol-enriched foods are increasingly marketed to lower cholesterol levels and atherosclerosis in the general population. Phytosterols reduce cholesterol absorption, but the molecular mechanism is controversial. We therefore investigated the phytosterol effects on cholesterol metabolism in human enterocyte, hepatocyte, and macrophage models relevant for sterol absorption, reverse transport, ...
- DOI:
- 10.3945/jn.111.157198
- PubMed:
- 22535758
-
http://dx.doi.org/10.3945/jn.111.157198
- Author:
- Naidoo, Nasheen; van Dam, Rob M.; Koh, Woon-Puay; Chen, Cynthia; Lee, Yian-Ping; Yuan, Jian-Min; Ong, Choon-Nam
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1046-1052
- ISSN:
- 0022-3166
- Subject:
- case-control studies; vitamin E; lifestyle; models; isomers; regression analysis; risk factors; case studies; myocardial infarction; antioxidant activity; adults; protective effect; Singapore
- Abstract:
- ... Vitamin E and coenzyme Q10 (CoQ10) have antioxidant effects that may benefit cardiovascular health. Meta-analyses of randomized controlled trials have not shown a protective effect of supplementation with the vitamin E isomer α-tocopherol on the risk of acute myocardial infarction (AMI), but data on other isomers and CoQ10 are limited. Our objective was to examine the association of the plasma con ...
- DOI:
- 10.3945/jn.111.155341
- PubMed:
- 22513986
- PubMed Central:
- PMC3349975
-
http://dx.doi.org/10.3945/jn.111.155341
- Author:
- Coles, Christian L.; Rahmathullah, Lakshmi; Kanungo, Reba; Katz, Joanne; Sandiford, Debora; Devi, Sheela; Thulasiraj, R. D.; Tielsch, James M.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1088-1094
- ISSN:
- 0022-3166
- Subject:
- Streptococcus pneumoniae; childhood; growth factors; growth retardation; infant growth; morbidity; mortality; neonates; nutritional status; risk factors; serotypes; vitamins; India
- Abstract:
- ... Nasopharyngeal colonization is the first step in the pathway to Streptococcus pneumoniae (Spn) infection, a leading cause of childhood morbidity and mortality. We investigated the effect of Spn colonization at ages 2 and 4 mo on growth at age 6 mo among 389 infants living in rural South India by using data from an Spn carriage study nested within a randomized, double-blind, placebo-controlled comm ...
- DOI:
- 10.3945/jn.111.156844
- PubMed:
- 22535764
- PubMed Central:
- PMC3349980
-
http://dx.doi.org/10.3945/jn.111.156844
- Author:
- Brunton, Janet A.; Baldwin, Mark P.; Hanna, Rodney A.; Bertolo, Robert F.
- Source:
- Journal of nutrition 2012 v.142 no.6 pp. 1004-1008
- ISSN:
- 0022-3166
- Subject:
- arginine; diet; free amino acids; jejunum; liver; liver protein; mucosa; muscle protein; muscles; neonates; nitrogen; nitrogen balance; piglets; proline; protein synthesis; total parenteral nutrition
- Abstract:
- ... Proline and arginine are each indispensable during parenteral feeding due to limited interconversion by an atrophied gut. Commercial amino acid parenteral products designed for neonates contain proline concentrations that differ by almost 4-fold. To assess the adequacy of the lowest concentration of proline provided in commercial total parenteral nutrition (TPN) products, we compared rates of tiss ...
- DOI:
- 10.3945/jn.111.154534
- PubMed:
- 22535763
-
http://dx.doi.org/10.3945/jn.111.154534