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- Basu, Arpita; Du, Mei; Leyva, Misti J.; Sanchez, Karah; Betts, Nancy M.; Wu, Mingyuan; Aston, Christopher E.; Lyons, Timothy J.
- Journal of nutrition 2010 v.140 no.9 pp. 1582-1587
- blueberries; cardiovascular diseases; risk factors; obesity; men; women; metabolic syndrome; functional foods; dietary supplements; randomized clinical trials; cardioprotective effect
- ... Among all fruits, berries have shown substantial cardio-protective benefits due to their high polyphenol content. However, investigation of their efficacy in improving features of metabolic syndrome and related cardiovascular risk factors in obesity is limited. We examined the effects of blueberry supplementation on features of metabolic syndrome, lipid peroxidation, and inflammation in obese men ...
- PubMed Central:
- Wu, Xianli; Kang, Jie; Xie, Chenghui; Burris, Ramona; Ferguson, Matthew E.; Badger, Thomas M.; Nagarajan, Shanmugam
- Journal of nutrition 2010 v.140 no.9 pp. 1628-1632
- blueberries; atherosclerosis; protective effect; apolipoproteins; mice; animal models; physiological regulation; protein synthesis; enzyme activity; oxidative stress; lipid peroxidation; biomarkers; experimental diets
- ... Protective effects of blueberries (BB) against atherosclerosis and potential underlying mechanisms in reducing oxidative stress were examined in apoE-deficient (apoE⁻ / ⁻) mice. ApoE⁻ / ⁻ mice were fed an AIN-93G diet (CD) or CD formulated to contain 1% freeze-dried whole BB for 20 wk. The mean lesion area for apoE⁻ / ⁻ mice fed BB was reduced by 39% (P lt 0.001) in the aorta sinus and 58% (P lt 0 ...