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- Author:
- Yamanaka, Hideharu; Okada, Shingo; Sanada, Hiromi
- Source:
- Journal of nutrition & intermediary metabolism 2017 v.8 pp. 51-59
- ISSN:
- 2352-3859
- Subject:
- collagen; dietary supplements; fibroblasts; metabolism; nutritional status; patients; peptides; pressure ulcers
- Abstract:
- ... Since collagen peptide stimulates fibroblast growth in skin, it may accelerate the healing of pressure ulcers. Therefore, the purpose of our study was to verify whether the intake of collagen peptides in the form of a supplement drink facilitates the healing of pressure ulcers. We conducted a multicenter, randomized, controlled trial in patients with pressure ulcers. Patients were randomized into ...
- DOI:
- 10.1016/j.jnim.2017.05.001
-
https://dx.doi.org/10.1016/j.jnim.2017.05.001
- Author:
- Iyaswamy, Ashok; Wankhar, Dapkupar; Loganathan, Sundareswaran; Shanmugam, Sambantham; Rajan, Ravindran; Rathinasamy, Sheeladevi
- Source:
- Journal of nutrition & intermediary metabolism 2017 v.8 pp. 41-50
- ISSN:
- 2352-3859
- Subject:
- B-cell lymphoma; acidosis; alanine transaminase; albino; alkaline phosphatase; animal models; apoptosis; aspartame; aspartate transaminase; caspase-3; caspase-9; folic acid; functional status; gene expression regulation; genes; hepatotoxicity; histopathology; homeostasis; immunohistochemistry; lactate dehydrogenase; liver; liver function; metabolites; methanol; methotrexate; necrosis; protein synthesis; rats; signal transduction; vacuoles; vitamin B deficiency
- Abstract:
- ... This study assesses the effect of long-term intake of aspartame on liver function and apoptosis signaling pathway in the Wistar albino rats. Several reports have suggested that methanol is one of the major metabolites of Aspartame. Non-primate animals are usually resistant to methanol-induced metabolic acidosis due to high levels of hepatic folate content; hence a folate deficiency model was induc ...
- DOI:
- 10.1016/j.jnim.2017.06.002
-
https://dx.doi.org/10.1016/j.jnim.2017.06.002
- Author:
- Nakamura, M.; Sugiura, M.; Shibata, Y.; Ojima, T.
- Source:
- Journal of nutrition & intermediary metabolism 2017 v.8 pp. 8-13
- ISSN:
- 2352-3859
- Subject:
- beta-cryptoxanthin; biomarkers; blood serum; cohort studies; long term effects; mandarin juice; men; metabolism; oxidative stress; randomized clinical trials; risk; satsumas; women; Japan
- Abstract:
- ... Cohort studies in Japan indicate that citrus fruit and β-cryptoxanthin–rich Satsuma mandarin are candidate foods for lowering cardiovascular risk; however, there have been few intervention studies of β-cryptoxanthin and Satsuma mandarin supplementation.A randomized, placebo-controlled, double-blind parallel trial was performed. Apparently healthy men and women were randomly assigned to two groups: ...
- DOI:
- 10.1016/j.jnim.2017.03.001
-
http://dx.doi.org/10.1016/j.jnim.2017.03.001
- Author:
- Aslibekyan, Stella; Irvin, Marguerite R.; Hidalgo, Bertha A.; Perry, Rodney T.; Jeyarajah, Elias J.; Garcia, Erwin; Shalaurova, Irina; Hopkins, Paul N.; Province, Michael A.; Tiwari, Hemant K.; Ordovas, Jose M.; Absher, Devin M.; Arnett, Donna K.
- Source:
- Journal of nutrition & intermediary metabolism 2017 v.8 pp. 1-7
- ISSN:
- 2352-3859
- Subject:
- CD4-positive T-lymphocytes; DNA methylation; cardiovascular diseases; cytokines; diet; drugs; environmental factors; epigenetics; family relations; genome; heritability; humans; intergenic DNA; lipids; loci; metabolism; metabolites; risk factors
- Abstract:
- ... Trimethylamine-N-oxide (TMAO), an atherogenic metabolite species, has emerged as a possible new risk factor for cardiovascular disease. Animal studies have shown that circulating TMAO levels are regulated by genetic and environmental factors. However, large-scale human studies have failed to replicate the observed genetic associations, and epigenetic factors such as DNA methylation have never been ...
- DOI:
- 10.1016/j.jnim.2017.03.002
- PubMed:
- 28439531
- PubMed Central:
- PMC5400362
-
https://dx.doi.org/10.1016/j.jnim.2017.03.002
- Author:
- Matsui, Tatsunobu; Ichikawa, Hiroshi; Fujita, Tomoka; Takagi, Tomohisa; Osada-Oka, Mayuko; Minamiyama, Yukiko
- Source:
- Journal of nutrition & intermediary metabolism 2017 v.8 pp. 21-28
- ISSN:
- 2352-3859
- Subject:
- Western blotting; apoptosis; caspase-3; caspase-8; cell viability; histidine; intestinal mucosa; kidney cells; kidneys; membrane potential; metabolism; mitochondria; mitochondrial membrane; patients; quality of life; rats
- Abstract:
- ... To reveal the importance of histidine in intestinal epithelial cells, we investigated whether reduction in histidine concentration affects cell viability and apoptosis in rat intestinal epithelial cells (IEC-6).Culture cells were incubated in DMEM with or without histidine. Cell viability was measured by the MTT assay. The expression of caspase-3, -8, -9, and -12 was evaluated by western blot anal ...
- DOI:
- 10.1016/j.jnim.2017.05.002
-
https://dx.doi.org/10.1016/j.jnim.2017.05.002
- Author:
- Martin Manuel, Palomar; Elena, Bru; Carolina, Maldonado Galdeano; Gabriela, Perdigón
- Source:
- Journal of nutrition & intermediary metabolism 2017 v.8 pp. 29-40
- ISSN:
- 2352-3859
- Subject:
- animal models; antigens; bacteria; blood serum; body weight; cholesterol; digestive system; fermented milk; food deprivation; glucose; goblet cells; histology; humoral immunity; immune response; immunization; intestinal microorganisms; macrophages; metabolism; mice; microvilli; ovalbumin; phagocytosis; probiotics; salmonellosis; spleen; triacylglycerols; villi
- Abstract:
- ... In a bifactorial stress mouse model we studied the effect of probiotic supplementation on biochemical parameter in serum, the intestinal impairment of the villi induced by stress, the systemic immune response and the susceptibility to intestinal infections. Probiotic effect was also evaluated on cells from the innate immunity. Mice were subjected to a stress protocol based on food deprivation and ...
- DOI:
- 10.1016/j.jnim.2017.06.001
-
https://dx.doi.org/10.1016/j.jnim.2017.06.001
- Author:
- Beckett, Emma Louise; Martin, Charlotte; Boyd, Lyndell; Porter, Teagan; King, Katrina; Niblett, Suzanne; Yates, Zoe; Veysey, Martin; Lucock, Mark
- Source:
- Journal of nutrition & intermediary metabolism 2017 v.8 pp. 14-20
- ISSN:
- 2352-3859
- Subject:
- Australians; blood serum; breadmaking; demographic statistics; eating habits; elderly; folic acid; food intake; homocysteine; issues and policy; metabolism; neural tube defects; risk factors; vitamin status; wheat flour; women; Australia
- Abstract:
- ... In 2009, Australia implemented mandatory folic acid fortification in wheat flour for bread-making. The primary aim was to improve folate status in reproductive-aged women to reduce neural tube defect incidence. However, folic acid consumption has consequently increased in all demographics. Blood folate is inversely associated with homocysteine levels, a risk factor for multiple diseases. Therefore ...
- DOI:
- 10.1016/j.jnim.2017.04.001
-
https://dx.doi.org/10.1016/j.jnim.2017.04.001
