Jump to Main Content
- Ruchirawat, Somsak, et al. Show all 6 Authors
- Journal of organic chemistry 2015 v.80 no.9 pp. 4516-4525
- alkynes; azides; diastereoselective synthesis; organic chemistry; quinoline; regioselectivity
- ... Regioselective synthesis of 3-bromoquinoline derivatives was achieved via a formal [4 + 2]-cycloaddition between N-aryliminium ion, generated from arylmethyl azides, and 1-bromoalkynes. This method could also be applied to other quinoline derivatives using appropriate alkynes. Moreover, the current strategy could be utilized for the diastereoselective synthesis of tetrahydroquinoline derivatives e ...