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Journal of proteomics
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7980-2020
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2020 v.216
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- Author:
- Guillem Estruch; Silvia Martínez-Llorens; Ana Tomás-Vidal; Raquel Monge-Ortiz; Miguel Jover-Cerdá; Paul B. Brown; David S. Peñaranda
- Source:
- Journal of proteomics 2020 v.216 pp. 103672
- ISSN:
- 1874-3919
- Subject:
- Sparus aurata; amino acids; aquaculture; aquaculture feeds; biometry; cytoskeleton; digestion; digestive tract; enterocytes; feed conversion; fish; fish meal; immune system; inflammation; ingredients; intestinal absorption; long term effects; nutrients; permeability; physiological transport; plant source protein; protein metabolism; proteome
- Abstract:
- ... The digestive tract, particularly the intestine, represents one of the main sites of interactions with the environment, playing the gut mucosa a crucial role in the digestion and absorption of nutrients, and in the immune defence. Previous researches have proven that the fishmeal replacement by plant sources could have an impact on the intestinal status at both digestive and immune level, compromi ...
- DOI:
- 10.1016/j.jprot.2020.103672
- https://doi.org/10.1016/j.jprot.2020.103672
- Author:
- C. Ruth Wang; Emily R. Bubner; Blagojce Jovcevski; Parul Mittal; Tara L. Pukala
- Source:
- Journal of proteomics 2020 v.216 pp. 103680
- ISSN:
- 1874-3919
- Subject:
- Bitis arietans; L-amino-acid oxidase; Pseudechis; amino acids; bioactive compounds; chromatography; drug design; fractionation; geometry; lectins; mass spectrometry; medicinal properties; phospholipase A2; phospholipases; protein composition; protein structure; proteomics; snake venoms; snakes; therapeutics
- Abstract:
- ... Snake venoms contain complex mixtures of proteins vital for the survival of venomous snakes. Aligned with their diverse pharmacological activities, the protein compositions of snake venoms are highly variable, and efforts to characterise the primary structures of such proteins are ongoing. Additionally, a significant knowledge gap exists in terms of the higher-order protein structures which modula ...
- DOI:
- 10.1016/j.jprot.2020.103680
- https://doi.org/10.1016/j.jprot.2020.103680
- Author:
- Jessica Gonnet; Lauranne Poncelet; Celine Meriaux; Elena Gonçalves; Lina Weiss; Nicolas Tchitchek; Eric Pedruzzi; Angele Soria; David Boccara; Annika Vogt; Olivia Bonduelle; Gregory Hamm; Rima Ait-Belkacem; Jonathan Stauber; Isabelle Fournier; Maxence Wisztorski; Behazine Combadiere
- Source:
- Journal of proteomics 2020 v.216 pp. 103670
- ISSN:
- 1874-3919
- Subject:
- antigen presentation; antigen-presenting cells; biomarkers; cell movement; chemoattractants; chemokine CXCL10; dermis; erythema; gene expression regulation; humans; image analysis; influenza vaccines; interleukin-8; lipids; metabolites; models; neutrophils; proteins; tandem mass spectrometry; vaccination
- Abstract:
- ... The skin plays a crucial role in host defences against microbial attack and the innate cells must provide the immune system with sufficient information to organize these defences. This unique feature makes the skin a promising site for vaccine administration. Although cellular innate immune events during vaccination have been widely studied, initial events remain poorly understood. Our aim is to d ...
- DOI:
- 10.1016/j.jprot.2020.103670
- https://doi.org/10.1016/j.jprot.2020.103670
- Author:
- Kuai Yu; Manolis Matzapetakis; Anita Horvatić; Marta Terré; Alex Bach; Josipa Kuleš; Natalia Yeste; Néstor Gómez; Laura Arroyo; Elisabet Rodríguez-Tomàs; Raquel Peña; Nicolas Guillemin; André M. de Almeida; Peter David Eckersall; Anna Bassols
- Source:
- Journal of proteomics 2020 v.216 pp. 103677
- ISSN:
- 1874-3919
- Subject:
- blood; dairy calves; diet; essential amino acids; leucine; metabolism; metabolome; milk replacer; nutritional status; proteome; skeletal muscle; threonine
- Abstract:
- ... In pre-weaning calves, both leucine and threonine play important roles in growth and muscle metabolism. In this study, metabolomics, proteomics and clinical chemistry were used to assess the effects of leucine and threonine supplementation added to milk replacer on 14 newborn Holstein male calves: 7 were fed a control diet (Ctrl) and 7 were fed the Ctrl diet supplemented with 0.3% leucine and 0.3% ...
- DOI:
- 10.1016/j.jprot.2020.103677
- https://doi.org/10.1016/j.jprot.2020.103677
- Author:
- Giulia Usai; Simona Cirrincione; Angela Re; Marcello Manfredi; Andrea Pagnani; Enrica Pessione; Roberto Mazzoli
- Source:
- Journal of proteomics 2020 v.216 pp. 103667
- ISSN:
- 1874-3919
- Subject:
- Clostridium cellulovorans; acetates; adenosine triphosphate; bacteria; biofuels; butanol; butyrates; carbon; carbon metabolism; cellulases; cellulolytic microorganisms; cellulose; ethanol production; fermentation; formates; genes; glucose; glutamate dehydrogenase; glycolysis; hemicellulose; lignocellulose; metabolic engineering; nitrogen; pectins; phosphates; proteomics; pyruvic acid; secretion
- Abstract:
- ... Clostridium cellulovorans is among the most promising candidates for consolidated bioprocessing (CBP) of cellulosic biomass to liquid biofuels (ethanol, butanol). C. cellulovorans metabolizes all the main plant polysaccharides and mainly produces butyrate. Since most butyrate and butanol biosynthetic reactions from acetyl-CoA are common, introduction of single heterologous alcohol/aldehyde dehydro ...
- DOI:
- 10.1016/j.jprot.2020.103667
- https://doi.org/10.1016/j.jprot.2020.103667
- Author:
- Cai Tie; Lili Liu; Teng Feng; Rina Sa; Qiangwei Xia; Handong Liang; Yonghui Mao
- Source:
- Journal of proteomics 2020 v.216 pp. 103676
- ISSN:
- 1874-3919
- Subject:
- albumins; antigens; biomarkers; humans; isoelectric focusing; kidney diseases; kidney function tests; mass spectrometry; patients; phospholipase A2; physicians; prognosis; urine
- Abstract:
- ... Membranous nephropathy (MN) is one of the most common causes of primary glomerular diseases worldwide. The M-type phospholipase A2 receptor (PLA2R), an antigen expressed in more than 70% of cases of idiopathic membranous nephropathy (IMN), is a biomarker which is now used by physicians for clinical diagnosis. Despite the prevalence of PLA2R in the cases of MN, it is not always effective to use PLA ...
- DOI:
- 10.1016/j.jprot.2020.103676
- https://doi.org/10.1016/j.jprot.2020.103676
- Author:
- Guomin Liu; Tiancheng Lu; Yalong Li; Yun Liu; Xuan Ji; Wenyuan Jia; Maolei Sun; Yungang Luo
- Source:
- Journal of proteomics 2020 v.216 pp. 103673
- ISSN:
- 1874-3919
- Subject:
- acne; autoimmunity; blood serum; bone marrow; catalytic activity; exosomes; gene ontology; genes; histones; immune response; inflammation; integrins; mitogen-activated protein kinase; pathogenesis; patients; phosphoprotein phosphatase; prognosis; protein subunits; protein-tyrosine kinases; proteome; proteomics; synovitis
- Abstract:
- ... Exosome proteomic analysis may reveal differentially abundant proteins that are of significance for clarifying the pathogenesis of SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) syndrome. Exosomes were isolated from the serum, bone marrow and skin tissue of the palm and toe pustular areas in a unique patient with SAPHO syndrome. The exosomes were not different from those of healthy ...
- DOI:
- 10.1016/j.jprot.2020.103673
- https://doi.org/10.1016/j.jprot.2020.103673
- Author:
- Mikel Azkargorta; Marta Bregón-Villahoz; Iraide Escobes; Jone Ibáñez-Pérez; Ibon Iloro; Maria Iglesias; Miren Diez-Zapirain; Aintzane Rabanal; Begoña Prieto; Maria-Dolores Moragues; Roberto Matorras; Felix Elortza
- Source:
- Journal of proteomics 2020 v.216 pp. 103652
- ISSN:
- 1874-3919
- Subject:
- antimicrobial peptides; antimicrobial properties; culture media; embryo culture; embryo implantation; embryo transfer; endometrium; humans; in vitro fertilization; mass spectrometry; microorganisms; nutrition; protein content; proteins; proteome; proteomics; spectrometers; superoxide dismutase
- Abstract:
- ... The composition of endometrial fluid reflects the status of the endometrium; it is a good atraumatic source of information on embryo implantation processes and possible pathological conditions. Although some attempts have been made to characterise its proteome, the catalogue of its proteins remains incomplete and little has been done to analyse the natural peptides it contains. Here, we present a ...
- DOI:
- 10.1016/j.jprot.2020.103652
- https://doi.org/10.1016/j.jprot.2020.103652
- Author:
- MHD Rami Al Shweiki; Patrick Oeckl; Petra Steinacker; Peggy Barschke; Christopher Pryce; Cornelia Dorner-Ciossek; Carlos Schönfeldt-Lecuona; Bastian Hengerer; Markus Otto
- Source:
- Journal of proteomics 2020 v.216 pp. 103679
- ISSN:
- 1874-3919
- Subject:
- amygdala; antidepressants; data collection; hippocampus; human health; image analysis; ketamine; mechanism of action; mental depression; mice; peptides; proteins; proteome; proteomics; tissues
- Abstract:
- ... Current understanding of the molecular mechanisms underlying ketamine's antidepressant effect remains largely incomplete. Recent imaging studies provide evidence for ketamine effects on amygdalo-hippocampal. This study in mice aimed to investigate acute proteomic changes after ketamine administration in various brain regions including amygdala and hippocampus. One hour after administration of s-ke ...
- DOI:
- 10.1016/j.jprot.2020.103679
- https://doi.org/10.1016/j.jprot.2020.103679
- Author:
- Renwen Zheng; Yuxian Xia; Nemat O. Keyhani
- Source:
- Journal of proteomics 2020 v.216 pp. 103681
- ISSN:
- 1874-3919
- Subject:
- Locusta migratoria; antennae; binding proteins; biochemical pathways; biomarkers; females; gene expression; genes; legs; locusts; males; melanogenesis; odor compounds; odorant receptors; palps; proteome; proteomics; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; riboflavin; ribosomes; sexual dimorphism; smell; tissues
- Abstract:
- ... Olfaction plays a critical role in mediating environmental chemical signals to affect behavior. Locusts are voracious feeders that can cause substantial agricultural and environmental damage. Here, we have identified 3473 proteins in the antennal proteome of the migratory locust, Locusta migratoria. Comparative analysis of sex variation in the antennal proteomes of male and female locusts using iT ...
- DOI:
- 10.1016/j.jprot.2020.103681
- https://doi.org/10.1016/j.jprot.2020.103681