Jump to Main Content
- Kwon, So Hee, et al. Show all 6 Authors
- Journal of proteomics 2014 v.102 pp. 137-147
- Drosophila melanogaster; binding proteins; epigenetics; eukaryotic cells; gene silencing; genes; heterochromatin; mass spectrometry; proteomics
- ... Heterochromatin protein 1 (HP1) was first described in Drosophila melanogaster as a heterochromatin associated protein required for epigenetic gene silencing. Most eukaryotes have at least three HP1 homologs that play differential roles in heterochromatin and euchromatin. However, despite the fact that the three HP1 proteins bind to different regions of the genome, several studies show that most o ...