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- Barsegov, Valeri, et al. Show all 6 Authors
- Journal of the American Chemical Society 2012 v.134 no.50 pp. 20396-20402
- energy; fibrin; humans; mechanical properties; models; phase transition
- ... We characterized the α-to-β transition in α-helical coiled-coil connectors of the human fibrin(ogen) molecule using biomolecular simulations of their forced elongation and theoretical modeling. The force (F)–extension (X) profiles show three distinct regimes: (1) the elastic regime, in which the coiled coils act as entropic springs (F < 100–125 pN; X < 7–8 nm); (2) the constant-force plastic regim ...
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