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- Li, Long, et al. Show all 11 Authors
- Journal of the American Chemical Society 2018 v.140 no.41 pp. 13335-13339
- DNA; binding capacity; blood serum; cellular microenvironment; circular dichroism spectroscopy; cytosine; energy transfer; oligonucleotides; pH; receptors; therapeutics
- ... Aptamers that recognize specific cells in a complex environment have emerged as invaluable molecular tools in bioanalysis and in the development of targeted therapeutics. The selective recognition of aptamers, however, can be compromised by the coexistence of target receptors on both target cells and other cells. To address this problem, we constructed a structure-switchable aptamer (SW-Apt) with ...